Influence of drying on the chemical composition and bioactivity of Piper aduncum (Piperaceae) essential oil against Aedes aegypti (Diptera: Culicidae)
DOI:
https://doi.org/10.33448/rsd-v10i8.17397Keywords:
Bioinsecticide; bioinsecticide; Vector control; vector control; Eupatoriochrome.; eupatoriochromeneAbstract
Piper species are producers of essential oils with high yield and promising chemical composition for both perfumery and the pharmaceutical industry. They present bioactivity against pathogens and against insect pests, whether agricultural or medical, such as Aedes aegypti, for example, a vector of arboviruses with a high incidence in tropical and subtropical regions. In this study, an investigation was carried out to elucidate the chemical composition of essential oils from the leaves and inflorescences of Piper aduncum collected in the state of Goiás, Brazil. Evaluating the interference of the drying process on yield, chemical composition and larvicide potential against Ae. aegypti. Leaves and inflorescences of P. aduncum were collected in the rural area of the municipality of Iporá-GO. Fresh and dried samples were processed separately and subjected to hydrodistillation for two hours. The oil obtained was qualitatively evaluated by gas-coupled chromatography and mass spectrometry. Greater yield was observed in samples submitted to the drying process. Oils obtained from fresh samples had a higher percentage of monoterpene hydrocarbons. Variation was observed between the major components of samples of fresh leaves and inflorescences, with eupatoriochrome being the major component in dried samples. Larvicidal activity against Ae. aegypti was considered promising (LC50<100µg/mL) in all samples. The results obtained showed a chemical composition different from that generally presented by P. aduncum. This reinforces the idea of intraspecific variability of essential oils and the need for chemical evaluation between samples even if they belong to the same species.
References
Adams, R.P. Identification of Essential Oil Components by Gas Chromatography/Mass Spectrometry, 4º ed. Allured Publishing Corporation, Illionois, 2007.
Albuquerque, J. S. Gama, E.; França, L. P.; De-Jesus, R. P. (2020). Atividade larvicida dos óleos essenciais de Piper dilatatum e Piper hostmannianum (Piperaceae) para o controle de Aedes aegypti (Culicidae) em laboratório. DêCiência em foco, 4(1), 22-28.
Alves E. D. L.; Biudes, M. (2008). Variabilidade temporal da precipitação em Iporá, GO – Um estudo climatológico. Revista de Ciências Ambientais, 4: 1-9.
Carballo-Arce AF, Raina V, Liu S, Liu R, Jackiewicz V, Carranza D, Arnason JT, Durst T. 2019. Potent CYP3A4 inhibitors derived from dillapiol and sesamol. ACS Omega, 4, 10915–10920.
Costa, J.G.M.; et al. (2010). Composição e toxicidade de óleos essenciais de espécies de Piper frente a larvas de Aedes aegypti L. (Diptera Culicidae). Latin American Journal of Pharmacy, 29(3), 463-467.
Costa, J.G.M.; Rodrigues, F.F.G.; Angelico, E.C.; Silva, M.R.; Mota, M.L.; Santos, N.K.A.; Cardoso, A.L.H.; Lemos, T.L.G. (2005). Chemical- biological study of the essential oils of Hyptis martiusii, Lippia sidoides and Syzigium aromaticum against larvae of Aedes aegypti and Culex quinquefaciatus. Brazilian Journal of Pharmacognosy, 15(4), 304-309.
Costa, L.C. (2005). Secagem e fragmentação da matéria seca no rendimento e composição do óleo essencial de capim-limão. Horticultura Brasileira, 23(2), 956-959.
Dool, H.V.D.; Kratz, P.D. (1963). A generalization of the retention index system including linear temperature programmed gas- liquid partition chromatography. Journal of Chromatograph A.
Fazolin, M.; Estrela, J.L.V.; Catoni, V.; Costa, C.R. (2006). Potencialidades da pimenta-de-macaco (Piper aduncum L.): características gerais e resultados de pesquisa. Rio Branco, AO: Embrapa Acre, 56p.
Gainza, Y.A.; Fantatto, R.R.; Chaves, F.C.M.; Bizzo, H.R.; Esteves, S.N.; Chagas, A.C.S. (2016). Piper aduncun against Haemonchus contrortus isolates: cross resistance the research of natural bioactive compounds. Brazilian Journal of Veterinary Parasitology, 25(4), 383-393.
Gogosz, M.A. et al. (2012). Anatomia foliar comparativa de nove espécies do gênero Piper (Piperaceae), Rodriguésia, 63(2): 405-417.
Judd, W. S.; Campbell, C. S.; Kellogg, E. A.; Stevens, P. S.; Donoghue, M. J. (2009). Sistemática Vegetal: um enfoque filogenético. 3ª Ed. Porto Alegre, Artemed.
Klocke, J.A., Balandrin, M.F., Adams, R.P., Kingsford, E. (1985). Inseticidal chromenes from the volatile oil of Hemizonia fitchii. Journal of Chemical Ecology, 11(6): 701-712.
Lemos, D.R.H.; Melo, E.C.; Rocha, R.P.; Barbosa, L.C.A.; Pinheiro, A.L. (2012). Influence of drying air temeprature on the chemical composition of the essential oil of melaleuca. Engenharia na agricultura, 20(1): 5-11.
Li, X.; Schuler, M.A.; Berembaum, M.R. (2007). Molecular mechanisms of metabolic resistence to synthetic and natural xenobiotics. Annual Review of Entomology, 52, 231-253.
Lima, R. N. (2019). Antitumor and Aedes aegypti Larvicidal Activities of Essential Oils from Piper klotzschianum, P. hispidum, and P. arboreum. Natural Product Communications, 14(7), 1-6.
Maia, J.G.S.; Zoghbi, M.G.S.; Andrade, E.H.A.; Santos, A.S.; Silva, M.L.; Luz, A.I.R.; Bastos, C.N. (1998). Constituents of the essencial oil of Piper aduncum L. growing iin the Amazon Region. Flavour and Fragrance Journal, 13(4), 269-272.
NIST – National Institute of Standards and Technology. (1999). Pc version 1.7 of the NIST/EPA/NIH Mass Spectral Library Norwalk. Perkin- Elmer Corp., CT, USA.
Oliveira, G.L.; Cardoso, S.K.; Celio, R.L.J.; Vieira, T.M.; Guimarães, E.F.; Figueiredo, L.S.; Martins, E.R.; Moreira, D.L.; Kaplan, M.A. (2012). Chemical study and larvicidal activity against Aedes aegypti of essencial oil of Piper aduncum L. (Piperaceae). Anais da Academia Brasileira de Ciências, 85(4), 1227-1234.
Pereira Filho, A. A. et al., (2021). Larvicidal activity of essential oils from Piper species against strains of Aedes aegypti (Diptera: Culicidae) resistant to pyrethroids. Frontiers in Plant Science, 12, 1-13.
Pohlit, A.M.; Pinto, A.C.S.; Mause, R. (2006). Piper aduncum L.: Planta pluripotente e Fonte de Substâncias fitoquímicas importantes. Revista Fitos, 2(1), 9-18, 2006.
Proksch, P. & Rodríguez, E. (1983). Chromenes and benzofurans of the Asteraceae, their chemistry and biological significance. Phytochemistry, 22 :2335–2348.
Santana, H.T.; Trindade, F.T.T.; Stabeli, R.G.; Silva, A.A.E.; Militão, J.S.L.T.; Fagundo, V.A. (2015). Essencial oils of leaves of Piper species display larvicidal activity against the dengue vector, Aedes aegypti (Diptera: Culicidae). Revista Brasileira de Plantas Medicinais, 17(1), 105-111, 2015.
Simas, N.K.; Lima, E.C.; Conceição, S.R.; Kuster, R.M.; Oliveira Folho, A.M. (2004). Produtos naturais para o controle da transmissão da dengue-atividade larvicida de Myroxylon balsamum (óleo vermelho) e de terpenóides e fenilpropanóides. Química Nova, 27(1), 46-49.
Simões, C.M.O. (2010). Farmacognosia: do produto natural ao medicamento. Editora da UFRGS e UFSC, 2010.
Simões, C.M.O.; Schenkel, E.P.; Mello, J.C.P.; Mentz, L.A.; Petrovick, P.R. (2017). Farmacognosia: do produto natural ao medicamento. Editora: Artmed.
Souza, P.J.C.; Barros, C.A.L.; Rocha, J.C.S.; Lira, D.S.; Monteiro, G.M.; Maia, J.G.S. (2008). Avaliação toxicological do óleo essencial de Piper aduncum L. Revista Brasileira de Farmacognosia, 18 (2), p.217-221.
Souza, S.J.O.; Ferri, P.H.; Fiuza, T.S.; Borges, L.L.; Paula, J.R. (2018). Chemical composition and seasonality variability of the Spiranthera odoratissima volatile oils leaves. Revista Brasileira de Farmacognosia, 28 (1): 16-20.
Taher, M., Amri, M.S., Susanti, D., Kudos, M.B.A., Nor, N.F.A.M., Syukri, Y. (2020). Medicinal uses, phytochemistry and pharmacological properties of Piper aduncum L. Sains Malaysiana, 49(8): 1829-1851.
Torres, L., Rojas, J., Rondón, M., Morales, A., Nieves, E. (2017). Insecticide activity of Argentina jahnii and Argentina pichinchensis (Asteraceae) against Lutzomyia migonei (Diptera: Psychodidae). Advanced Biomedical Research, 6, 1-5.
Valadares, A. C. F.; Alves, C. C. F.; Alves, J. M.; De-Deus, I. P.; Oliveira-Filho, J. G.; Dos-Santos, T. C.; Dias, H. J.; Crotti, A. E. M.; Miranda, M. L. D. (2018). Essential oils from Piper aduncum inflorescences and leaves: Chemical composition and antifungal activity against Sclerotinia sclerotiorum. Anais da Academia Brasileira de Ciências, 93(3), 2691-2699.
Vila, R. (2005). Unusual composition of the essential oils from the leaves of Piper aduncum. Flavour and Fragrance Journal, 20, p.67-69.
WHO – World Health Organization. Guidelines for laboratory and fields testing of mosquito larvicides. 2005.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2021 Thais Silva Santos; Taynara Ellen Sardeiro Vieira; José Realino de Paula; Jerônimo Raimundo de Oliveira Neto; Luiz Carlos da Cunha; Adelair Helena dos Santos; Camila Aline Romano
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
