Cerebral venous thrombosis and the use oral contraceptives: An integrative review
DOI:
https://doi.org/10.33448/rsd-v10i8.17428Keywords:
Oral contraceptives;; Trombosis Intracraneal; Female contraception.Abstract
The aim of the study was to relate research on cerebral venous thrombosis with the use of combined oral contraceptives. This is an integrative literature review carried out using the following databases: LILACS, Scielo, Periódicos Capes, Medline PubMed, Cochrane Library and Science Direct, using the descriptors: "contraceptive agents", "intracranial embolism thrombosis", "thrombosis" "intracranial thrombosis". The Boolean operator "AND" was used between the descriptors to select the articles. The guiding question, elaborated through the PICO (Patient, Intervention, Control, Outcome) methodology, was: "Do oral contraceptives trigger cerebral venous thrombosis?". In the results, 47 articles were found, and 35 were excluded for not presenting a relationship between cerebral venous thrombosis and oral contraceptives. Thus, 12 articles were selected to compose this review. It can be concluded that the risk of venous thrombotic events in users of combined oral contraceptives is increased. Therefore, it is important to emphasize the rational use of these drugs, as well as the understanding for the early diagnosis of cerebral venous thrombosis.
References
Bahall, M., & Santlal, M. (2017). Norethisterone enanthate-induced cerebral venous sinus thrombosis (CVST). BMJ Case Reports, 2017, bcr-2017-222418. https://doi.org/10.1136/bcr-2017-222418
Callai, T., Daronco, F., Konrad, N. L., Wichmann, J. F., Costa, F., & Prezzi, S. H. (2017). Tabagismo e uso de anticoncepcionais orais relacionados a fenômenos tromboembólicos: Relato de caso e revisão de literatura. Reprodução & Climatério, 32(2), 138–144. https://doi.org/10.1016/j.recli.2016.11.004
Gronich, N., Lavi, I., & Rennert, G. (2011). Higher risk of venous thrombosis associated with drospirenone-containing oral contraceptives: A population-based cohort study. CMAJ: Canadian Medical Association Journal = Journal de l’Association Medicale Canadienne, 183(18), E1319-1325. https://doi.org/10.1503/cmaj.110463
Huang, Q., Chai, X., Xiao, C., & Cao, X. (2019). A case report of oral contraceptive misuse induced cerebral venous sinus thrombosis and dural arteriovenous fistula. Medicine, 98(33), e16440. https://doi.org/10.1097/MD.0000000000016440
Jick, S. S., & Hernandez, R. K. (2011). Risk of non-fatal venous thromboembolism in women using oral contraceptives containing drospirenone compared with women using oral contraceptives containing levonorgestrel: Case-control study using United States claims data. BMJ (Clinical Research Ed.), 342, d2151. https://doi.org/10.1136/bmj.d2151
Kesieme, E., Kesieme, C., Jebbin, N., Irekpita, E., & Dongo, A. (2011). Deep vein thrombosis: A clinical review. Journal of Blood Medicine, 2, 59–69. https://doi.org/10.2147/JBM.S19009
Komro, J., & Findakly, D. ([s.d.]). Cerebral Venous Sinus Thrombosis in Adults with Prothrombotic Conditions: A Systematic Review and a Case from Our Institution. Cureus, 12(4), e7654. https://doi.org/10.7759/cureus.7654
Leal, T., & Bakker, B. (2017). A mulher bioquímica: Invenções do feminino a partir de discursos sobre a pílula anticoncepcional. Revista Eletrônica de Comunicação, Informação e Inovação em Saúde, 11(3), Article 3. https://doi.org/10.29397/reciis.v11i3.1303
Lima, A. C. S., Martins, L. C. G., Lopes, M. V. de O., Araújo, T. L. de, Lima, F. E. T., Aquino, P. de S., & Moura, E. R. F. (2017). Influence of hormonal contraceptives and the occurrence of stroke: Integrative review. Revista Brasileira de Enfermagem, 70, 647–655. https://doi.org/10.1590/0034-7167-2016-0056
Luz, A. L. R., Barros, L. de S. R., & Branco, A. C. da S. C. (2021). Métodos contraceptivos: Principais riscos e efeitos adversos. Revista de Casos e Consultoria, 12(1), e24112–e24112.
Miranda, A. A. M., Silva, C. G. de O. e, Thimoteo, G. M., Assis, L. F., Del’Duca, A., Carvalho, A. R. de, & Miranda, J. P. L. de. (2016). Conhecimentos acerca de dst/aids e métodos contraceptivos dos discentes dos cursos integrados do IF sudeste MG – campus Juiz de Fora, Brasil - Knowledge of STD/AIDS and Contraceptive Methods in Students of Integrated Techinical Courses at the IF Sudeste M. Multiverso: Revista Eletrônica do Campus Juiz de Fora - IF Sudeste MG, 1(1), 25–36.
Panos, G. D., Panos, L. D., Digklia, A., Hafezi, F., & Gatzioufas, Z. (2014). Unusual Presentation of Cerebral Venous Sinus Thrombosis Associated with Contraceptive Usage. Journal of Ophthalmic & Vision Research, 9(2), 281–284.
Parkin, L., Sharples, K., Hernandez, R. K., & Jick, S. S. (2011). Risk of venous thromboembolism in users of oral contraceptives containing drospirenone or levonorgestrel: Nested case-control study based on UK General Practice Research Database. BMJ (Clinical Research Ed.), 342, d2139. https://doi.org/10.1136/bmj.d2139
Patil, V. C., Choraria, K., Desai, N., & Agrawal, S. (2014). Clinical profile and outcome of cerebral venous sinus thrombosis at tertiary care center. Journal of Neurosciences in Rural Practice, 5(3), 218–224. https://doi.org/10.4103/0976-3147.133559
Petitti, D. B. (2012). Hormonal Contraceptives and Arterial Thrombosis—Not Risk-free but Safe Enough. New England Journal of Medicine, 366(24), 2316–2318. https://doi.org/10.1056/NEJMe1204769
Renowden, S. (2004). Cerebral venous sinus thrombosis. European Radiology, 14(2), 215–226. https://doi.org/10.1007/s00330-003-2021-6
Santos, G. R., André, R., Pereira, S. L., Parreira, T., & Machado, E. (2011). Trombose Venosa Cerebral: Análise Retrospectiva de 49 Casos. https://rihuc.huc.min-saude.pt/handle/10400.4/1018
Silva, C. S. da, Sá, R., & Toledo, J. (2019). Métodos Contraceptivos e Prevalência de Mulheres Adultas e Jovens com risco de Trombose, no Campus Centro Universitário do Distrito Federal-UDF. REVISA (Online), 190–197.
Souza, N., Holanda, C., Holanda, V., Zapata, M., de Oliveira, J., & Ribeiro, C. (2018). Trombose venosa de múltiplos seios: Relato de caso. 37. https://doi.org/10.1055/s-0038-1672736
Stegeman, B. H., de Bastos, M., Rosendaal, F. R., van Hylckama Vlieg, A., Helmerhorst, F. M., Stijnen, T., & Dekkers, O. M. (2013). Different combined oral contraceptives and the risk of venous thrombosis: Systematic review and network meta-analysis. BMJ (Clinical Research Ed.), 347, f5298. https://doi.org/10.1136/bmj.f5298
Xu, F., Liu, C., & Huang, X. (2017). Oral contraceptives caused venous sinus thrombosis complicated with cerebral artery infarction and secondary epileptic seizures: A case report and literature review. Medicine, 96(51), e9383. https://doi.org/10.1097/MD.0000000000009383
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2021 Leonardo Soares Ribeiro Alves da Rocha; Maria Eduarda Barres Vieira; Angélica Augusta Grigoli Dominato
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
