Bronchiolitis obliterans in pediatric patient associated with exposure to cocaine and other abuse drugs during the gestational period
Keywords:Bronchiolitis Obliterans; Cocaine; Gestational age; Pediatrics.
There is still little information in the literature about the association between exposure of pregnant women to drugs of abuse, including cocaine, and the development of bronchiolitis obliterans (BO) in the neonate. In this case report, we covered the follow-up over the years of a male pediatric patient who was admitted as a wheezing infant and who, after evaluations and observance of suggestive clinical and imaging criteria, was diagnosed with BO. Therefore, the findings of this report foster the literature and shed light on a causal relationship between exposure of pregnant women to drugs of abuse and the development of BO in the newborn, as well as on the epidemiological profile, clinical and imaging diagnosis and therapy (medications and oxygen therapy) in the course of the disease in pediatric patients and their comorbidities, also directing future strategies for the management of patients with BO.
Aguerre, V., Castaños, C., Pena, H. G., et al. (2010). Postinfectious bronchiolitis obliterans in children: clinical and pulmonary function findings. Pediatr Pulmonol, 45, 1180-5.
Calabrese, C., Corcione, N., Rea, G., et al. (2016). Impact of long-term treatment with inhaled corticosteroids and bronchodilators on lung function in a patient with post-infectious bronchiolitis obliterans. J Bras Pneumol, 42(3), 228-31.
Callahan, S. J., Vranic, A., Flors L., et al. (2019). Sporadic Obliterative Bronchiolitis: Case Series and Systematic Review of the Literature. Mayo Clin Proc Inn Qual Out, 3(1), 86-93
Champs, N. S., Lasmar, L. M. L. B. F., Camargos, C. M., et al. (2011). Post-infectious bronchiolitis obliterans in children. Jornal de Pediatria, 87(3), 187-198.
Chang, A. B., Masel, J. P., & Masters, B. (1998). Post-infectious bronchiolitis obliterans: clinical, radiological and pulmonary function sequelae. Pediatr Radiol, 28, 23-9.
Colom, A. J., & Teper, A. M. a. (2009). Postinfectious bronchiolistis obliterans. Arch Argent Pediatr, 107, 160-7
Colom, A. J., Teper, A. M. b. (2009). Clinical prediction rule to diagnose post-infectious bronchiolitis obliterans in children. Pediatr Pulmonol, 44, 1065-9.
de Almeida, P., Guimarães, M. J. B., Costa, M. G., et al. (2002). Bronquiolite obliterante na forma nodular. J Pneumol, 28(6), 335-8.
Fischer, G. B., Sarria, E. E., Mattiello, R., et al. (2010). Post Infectious bronchiolitis obliterans in children. Paediatr Respir Rev, 11, 233-9.
Garipo, A. L., & Capelozzi, V. L. (2006). Estudo morfométrico da imunidade celular e remodelamento no eixo pré-acinar na indução do colágeno tipo V em um modelo de bronquiolite obliterante. 186 f. Tese (Doutorado) - Curso de Fisiopatologia Experimental, Faculdade de Medicina da Universidade de São Paulo, São Paulo, 2006.
Kim, M. J., & Lee, K. Y. (1996). Bronchiolitis obliterans in children with Stevens-Johnson syndrome: follow-up with high resolutions CT. Pediatr Radiol, 26, 22-5.
Lin, E., Limper, A. H., & Moua, T. (2018). Obliterative bronchiolitis associated with rheumatoid arthritis: analysis of a singlecenter case series. BMC Pulmonary Medicine, 18, 105.
Lino, C. A., Batista, A. K. M., Soares, M. A. D., et al. (2013). Bronquiolite obliterante: perfil clínico e radiológico de crianças acompanhadas em ambulatório de referência. Rev Paul Pediatr, 31(1), 10-16.
Lobo, A. L., Guardiano, M., Nunes, T., et al. (2007). Bronquiolite obliterante pós-infecciosa na criança. Revista Portuguesa de Pneumologia, 13(4), 495-509.
Santos, R. V., Rosário, N. A., Ried, C. A. (2004). Postinfectious bronchiolitis obliterans: clinical aspects and complementary tests of 48 children. J Bras Pneumol, 30, 20-5.
Sarria, E. E., Mundstock, E., Machado, D. G., et al. (2018). Health-related quality of life in patients with bronchiolitis obliterans. J Pediatr, 94(4), 374-379.
Silva, C. I. S., & Müller, N. L. (2008). Obliterative Bronchiolitis. Springer, 293-323. In: Contemporary Medical Imaging: CT of the Airways, Edited by: P. M. Boiselle and D. A. Lynch©, Humana Press, Totowa, NJ (2008).
Smith, K. J., Dishop, M. K., Fan, L. L., et al. (2010). Diagnosis of bronchiolitis obliterans with computed tomography in children. Pediatr Allergy Immunol Pulmonol, 23, 253-9.
Teper, A., Fischer, G. B., Jones, M. H. (2002). Seqüelas respiratórias de doenças virais: do diagnóstico ao tratamento. Jornal de Pediatria, 78, 187-194.
Terra Filho, M., Yen, C. C., Santos, U. P., et al. (2004). Alterações pulmonares em usuários de cocaína. Sao Paulo Medical Journal, 122(1), 26-31.
Verleden, G. M., Vanaudenaerde, B. M., Dupont, L. J., et al. (2006). Azithromycin reduces airway neutrophilia and interleukin-8 in patients with bronchiolitis obliterans syndrome. Am J Respir Crit Care Med, 174, 566-70.
Zhang, L., Silva, F. A. (2000). Bronquiolite obliterante em crianças: bronchiolitis obliterans in children. Jornal de Pediatria, 76(3), 185-192.
Zheng, Z., Yao, Z., Wu, K., et al. (2020). The diagnosis of pandemic coronavirus pneumonia: A review of radiology examination and laboratory test. Journal of Clinical Virology, 128, 104396.
Yates, B., Murphy, D. M., Forrest, I. A., et al. (2005). Azithromycin reverses airflow obstruction in established bronchiolitis obliterans syndrome. Am J Respir Crit Care Med, 172, 772-5.
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Copyright (c) 2021 Henrique Rodrigues de Souza Moraes; Matheus Henrique Defendi Barboza; Juliana Antunes Tucci; Jamil de Barros Neto; Lucas Ferreira de Carvalho; Cláudio Daniel Cerdeira; Maísa Moscardini Moreira Herker Souza
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