Psychotic disorders associated with the climate period




Menopause; Depression; Climacteric.


Menopause is a period composed of several changes and transformations in the woman's life, characterizing the end of their reproductive period. Thus, the significant decrease in hormones in the female body results in a wide range of unpleasant signs and symptoms characteristic of this phase, with emphasis on psychic manifestations. The objective of the work is to carry out a bibliographic survey about the psychiatric disorders manifested during the menopause period. A search was carried out in the Pubmed, SciELO, Lilacs and Cochrane Library databases with the descriptors “Menopause” OR “Climacteric” OR “Middle Aged” AND “Mental disorders” OR “depression” OR “anxiety” including articles published in 2010 to 2020. The results show that depression and anxiety are among the most common psychiatric disorders in the period and that economic, social and cultural factors can influence these symptoms.


Potter, B., Schrager, S., Dalby, J., Torell, E., & Hampton, A. (2018). Primary care—Clinics in office practice. Menopause, 45(4), 625-641.

Baker, F. C., De Zambotti, M., Colrain, I. M., & Bei, B. (2018). Sleep problems during the menopausal transition: prevalence, impact, and management challenges. Nature and science of sleep, 10, 73.

Prairie, B. A., Wisniewski, S. R., Luther, J., Hess, R., Thurston, R. C., Wisner, K. L., & Bromberger, J. T. (2015). Symptoms of depressed mood, disturbed sleep, and sexual problems in midlife women: cross-sectional data from the Study of Women's Health Across the Nation. Journal of women's health, 24(2), 119-126.

Monteleone, P., Mascagni, G., Giannini, A., Genazzani, A. R., & Simoncini, T. (2018). Symptoms of menopause—global prevalence, physiology and implications. Nature Reviews Endocrinology, 14(4), 199-215.

Zhu, D., Chung, H. F., Dobson, A. J., Pandeya, N., Brunner, E. J., Kuh, D., ... & Mishra, G. D. (2020). Type of menopause, age of menopause and variations in the risk of incident cardiovascular disease: pooled analysis of individual data from 10 international studies. Human Reproduction, 35(8), 1933-1943.

Riecher-Rossler, A., & De Geyter, C. (2007). O futuro papel do tratamento com estrogênios na saúde mental. Swiss Medical Weekly , 137 (41-42), 565-572.

Nazarpour, S., Simbar, M., & Tehrani, F. R. (2016). Factors affecting sexual function in menopause: A review article. Taiwanese Journal of Obstetrics and Gynecology, 55(4), 480-487.

Oppermann, K., Fuchs, S. C., Donato, G., Bastos, C. A., & Spritzer, P. M. (2012). Physical, psychological, and menopause-related symptoms and minor psychiatric disorders in a community-based sample of Brazilian premenopausal, perimenopausal, and postmenopausal women. Menopause, 19(3), 355-360.

Galvão, L. L. L. F., Farias, M. C. S., Azevedo, P. R. M. D., Vilar, M. J. P., & Azevedo, G. D. D. (2007). Prevalência de transtornos mentais comuns e avaliação da qualidade de vida no climatério. Revista da Associação Médica Brasileira, 53, 414-420.

Pertesi, S., Coughlan, G., Puthusseryppady, V., Morris, E., & Hornberger, M. (2019). Menopause, cognition and dementia–A review. Post reproductive health, 25(4), 200-206.

Stute, P., Spyropoulou, A., Karageorgiou, V., Cano, A., Bitzer, J., Ceausu, I., ... & Lambrinoudaki, I. (2020). Management of depressive symptoms in peri-and postmenopausal women: EMAS position statement. Maturitas, 131, 91-101.

Truong, D., & Marsh, W. (2019). Bipolar Disorder in the Menopausal Transition. Current psychiatry reports, 21(12), 1-7.

Yanikkerem, E., Göker, A., Çakır, Ö., & Esmeray, N. (2018). Effects of physical and depressive symptoms on the sexual life of Turkish women in the climacteric period. Climacteric, 21(2), 160-166.

Slopien, R., Pluchino, N., Warenik-Szymankiewicz, A., Sajdak, S., Luisi, M., Drakopoulos, P., & Genazzani, A. R. (2018). Correlation between allopregnanolone levels and depressive symptoms during late menopausal transition and early postmenopause. Gynecological Endocrinology, 34(2), 144-147.

Quiroga, A., Larroy, C., & González-Castro, P. (2017). Climacteric symptoms and their relation to feminine self-concept. Climacteric, 20(3), 274-279.

Chou, C. H., Ko, H. C., Wu, J. Y. W., Chang, F. M., & Tung, Y. Y. (2015). Effect of previous diagnoses of depression, menopause status, vasomotor symptoms, and neuroticism on depressive symptoms among climacteric women: A 30-month follow-up. Taiwanese Journal of Obstetrics and Gynecology, 54(4), 385-389.

Gibbs, Z., Lee, S., & Kulkarni, J. (2013). Factors associated with depression during the perimenopausal transition. Women's Health Issues, 23(5), e301-e307.

Gharaibeh, M., Al-Obeisat, S., & Hattab, J. (2010). Severity of menopausal symptoms of Jordanian women. Climacteric, 13(4), 385-394.

Tangen, T., & Mykletun, A. (2008). Depression and anxiety through the climacteric period: an epidemiological study (HUNT-II). Journal of Psychosomatic Obstetrics & Gynecology, 29(2), 125-131.

GALLICCHIO, Lisa et al. Correlates of depressive symptoms among women undergoing the menopausal transition. Journal of psychosomatic research, v. 63, n. 3, p. 263-268, 2007.

Payne, J. L., Roy, P. S., Murphy-Eberenz, K., Weismann, M. M., Swartz, K. L., McInnis, M. G., ... & Potash, J. B. (2007). Reproductive cycle-associated mood symptoms in women with major depression and bipolar disorder. Journal of affective disorders, 99(1-3), 221-229.

Amore, M., Di Donato, P., Berti, A., Palareti, A., Chirico, C., Papalini, A., & Zucchini, S. (2007). Sexual and psychological symptoms in the climacteric years. Maturitas, 56(3), 303-311.

Travers, C., O'neill, S. M., King, R., Battistutta, D., & Khoo, S. K. (2005). Greene Climacteric Scale: norms in an Australian population in relation to age and menopausal status. Climacteric, 8(1), 56-62.

Estrela, C. (2018). Metodologia Científica: Ciência, Ensino, Pesquisa. Editora Artes Médicas.

Pereira A. S. et al. (2018). Metodologia da pesquisa científica. [free e-book]. Santa Maria/RS. Ed. UAB/NTE/UFSM.



How to Cite

NEGREIROS, B. A. de .; FEITOSA, Y. P. .; RIBEIRO, Y. C. F. .; PEREIRA JUNIOR , J. L. . Psychotic disorders associated with the climate period. Research, Society and Development, [S. l.], v. 10, n. 10, p. e371101018061, 2021. DOI: 10.33448/rsd-v10i10.18061. Disponível em: Acesso em: 2 mar. 2024.



Health Sciences