Larvicidal activity of hydroalcoholic extracts of Persea americana Mill. Seeds against Aedes aegypti
DOI:
https://doi.org/10.33448/rsd-v10i10.18144Keywords:
Persea americana; Bioativos; Arboviroses; Vetores.Abstract
This study aimed to evaluate the phytochemical composition of hydroalcoholic extracts from the seeds of Persea americana (avocado) and evaluate the larvicidal activity against Aedes aegypti. The extracts were obtained by maceration in a 70% PA ethanol extractant solvent in 1:4/1:6/1:8 hydromodules (7 days), with subsequent concentration in a rotaevaporator. The larvicidal activity was performed by the method recommended by the WHO Lethal Concentration 50% against Aedes aegypti larvae with statistics by the Probit method. Toxicity to non-target organisms was verified by the Artemia salina test. Activity was observed against Aedes aegypti larvae with LC50 ranging from 181.72-401.96 mg L-1 with a 95% confidence interval. Finally, it states that the extract of P. americana has potential for larvicidal activity and does not present toxicity to target organisms, showing itself to be a sustainable alternative for the control and combat of Aedes aegypti larvae.
References
Amado, D. A. V., Helmann, G. A. B., Detoni, A. M., Carvalho, S. L. C. D., Aguiar, C. M. D., Martin, C. A., & Cottica, S. M. (2019). Antioxidant and antibacterial activity and preliminary toxicity analysis of four varieties of avocado (Persea americana Mill.). Brazilian Journal of Food Technology, 22.
Agrela, I. F., Hidalgo, Y., & Herrera, F. (2014). Efecto larvicida de extractos metanólicos obtenidos de semillas y hojas de Persea americana (Laurales: Lauraceae)(aguacate) sobre Aedes aegypti (Diptera: Culicidae). Boletín de Malariología y Salud Ambiental, 54(2), 199-207.
Chang, M. S., Christophel, E. M., Gopinath, D., & Abdur, R. M. (2011). Challenges and future perspective for dengue vector control in the Western Pacific Region. Western Pacific surveillance and response journal: WPSAR, 2(2), 9.
Colegate, S. M., & Molyneux, R. J. (Eds.). (2007). Bioactive natural products: detection, isolation, and structural determination. CRC press.
Deuschle, V. C., Brusco, I., Piana, M., Faccin, H., de Carvalho, L. M., Oliveira, S. M., & Viana, C. (2019). Persea americana Mill. crude extract exhibits antinociceptive effect on UVB radiation-induced skin injury in mice. Inflammopharmacology, 27(2), 323-338.
Dolabela, M.F. (1997) Triagem in vitro para atividade antitumoral e anti Trypanossoma cruzi de extratos vegetais, produtos naturais e substâncias sintéticas. Dissertação (Mestrado), Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais-UFMG, Belo Horizonte, 128 p.
Dabas, D., M Shegog, R., R Ziegler, G., & D Lambert, J. (2013). Avocado (Persea americana) seed as a source of bioactive phytochemicals. Current pharmaceutical design, 19(34), 6133-6140.
Farmacopeia Brasileira. (5a ed.), ANVISA, 2010.
Ferrari, R. A. (2015). Nota Científica: Caracterização físico-química do óleo de abacate extraído por centrifugação e dos subprodutos do processamento. Braz. J. Food Technol., 18, 79-84.
Finney, D. J. (1952). Probit analysis: a statistical treatment of the sigmoid response curve. Cambridge university press, Cambridge.
Gobbo-Neto, L., & Lopes, N. P. (2007). Plantas medicinais: fatores de influência no conteúdo de metabólitos secundários. Química nova, 30(2), 374-381.
Ghosh, A., Chowdhury, N., & Chandra, G. (2012). Plant extracts as potential mosquito larvicides. The Indian journal of medical research, 135(5), 581.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2021 Ana Paula Muniz Serejo; Gustavo Oliveira Everton; Helene do Carmo Castro Lacerda; Ana Patrícia Matos Pereira; João Pedro Mesquita Oliveira; Thaylanna Pinto de Lima; Maria Giulia Alves Carneiro Felizardo; Denise Fernandes Coutinho
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
