Potentially malignant lesions of the maxillofacial region

Authors

DOI:

https://doi.org/10.33448/rsd-v10i11.19452

Keywords:

Lichen Planus Oral; Oral leukoplakia; Oral Cancer; Erythroplasia.

Abstract

Oral squamous cell carcinoma (OEC) is the most common type of malignant neoplasm among head and neck tumors, accounting for more than 90% of cases and, despite advances in therapeutic measures, most tumors are diagnosed at a late stage of the disease , resulting in poor prognosis and low survival rates. Disorders with potential for malignancy (MPD) are clinical and histopathological abnormalities, at the cellular level, which can assume the character of a malignant tumor at any time, but can remain stable for a considerable time. Literature points out that about 80% of oral cancers are progressions of MPD. Knowing the lesions with potential for malignancy becomes important for early diagnosis of oral cancer, improving prognosis and survival rates. Given the above, this study aims to review the literature on lesions with potential for malignancy, addressing their main characteristics that make it possible to identify them. For the construction of this article, a bibliographic survey was carried out in the SciVerse Scopus, Scientific Electronic Library Online (Scielo), Virtual Health Library (BVS) and U.S. National Library of Medicine (PUBMED) databases. Articles from 2010 to 2021 were selected. The results of this research show that there are four main lesions with great potential to become oral cancer, namely leukoplakia, erythroplasia, actinic kielitis and oral lichen planus.

References

Arnaud, R. R., Soares, M. S. M., Paiva, M. A. F. de, Figueiredo, C. R. L. V. de, Santos, M. G. C. dos, & Lira, C. C. (2014). Queilite actínica: avaliação

histopatológica de 44 casos. Revista de Odontologia Da UNESP, 43(6), 384–389. https://doi.org/10.1590/1807-2577.1038

Ceita, J., & Pessoa, U. F. (2014). Líquen Plano Oral – Lesão Pré-Maligna ?

Chen, X., Zhao, W., Chen, S., & Yu, D. (2021). Mutation profiles of oral squamous cell carcinoma cells. Advances in Oral and Maxillofacial Surgery, 2,

https://doi.org/https://doi.org/10.1016/j.adoms.2021.100026

Dantas Da Silveira, É. J., Lopes, M. F. F., Silva, L. M. M., Ribeiro, B. F., Lima, K. C., & Queiroz, L. M. G. (2009). Potentially malignant oral lesions: Clinical

and morphological analysis of 205 cases. Jornal Brasileiro de Patologia e Medicina Laboratorial, 45(3), 233–238.

https://doi.org/10.1590/s167624442009000300008

Gonzaga, A. K. G., Mafra, R. P., da Silva, L. P., de Almeida Freitas, R., de Souza, L. B., & Pinto, L. P. (2020). Actinic cheilitis: Morphometric parameters and

its relationship with the degree of epithelial dysplasia. Acta Histochemica, 122(1), 151452. https://doi.org/https://doi.org/10.1016/j.acthis.2019.151452

Guzmán G, P., Villaseca H, M., Antonio P, L., Araya O, J., Aravena M, P., Cravero P, C., Pino M, P., & Roa S, J. (2015). Carcinoma epidermoide oral y orofaríngeo: Estudio clínico-patológico. Revista Chilena de Cirugía, 63(3), 250–256. https://doi.org/10.4067/s0718-40262011000300003

Hosni, Elaini Sickert, Fernanda Gonçalves Salum, Karen Cherubini, Liliane Soares Yurgel, and Maria Antonia Zancanaro Figueiredo. 2009. “Oral

Erythroplakia and Speckled Leukoplakia: Retrospective Analysis of 13 Cases.” Brazilian Journal of Otorhinolaryngology 75(2):295–99.

Imam, A. (2013). Alterações potencialmente malignas da mucosa oral. Journal of Chemical Information and Modeling, 53(9), 1689–1699.

José, H., Coelho, R., Macedo, C., Antonio, M., & Costa, N. (2019). Uma análise retrospectiva de lesões malignas e desordens a retrospective analysis of malignant and potentially malignant disorders diagnosed in seven years Resumo Abstract. 46(1), 5–13.

Leite, Adriana Caroline, and Nathalia Torres Assay. 2019. “Descoberta de Carcinoma de Células Escamosas Em Lesão Previamente Diagnosticada Como

Líquen Plano Oral: Malignização Ou Erro de Diagnóstico Inicial?” 8:178–81.

Maia, Haline Cunha de Medeiros, Najara Alcântara Sampaio Pinto, Joabe Dos Santos Pereira, Ana Miryam Costa de Medeiros, Éricka Janine Dantas da

Silveira, and Márcia Cristina da Costa Miguel. 2016. “Potentially Malignant Oral Lesions: Clinicopathological Correlations.” Einstein (Sao Paulo, Brazil)

(1):35–40.

Mascitti, M., Orsini, G., Tosco, V., Monterubbianesi, R., Balercia, A., Putignano, A., Procaccini, M., & Santarelli, A. (2018). An overview on current non-invasive diagnostic devices in oral oncology. Frontiers in Physiology, 9(OCT), 1–8. https://doi.org/10.3389/fphys.2018.01510

Metzger, K., Moratin, J., Horn, D., Pilz, M., Ristow, O., Hoffmann, J., Freier, K., Engel, M., & Freudlsperger, C. (2021). Treatment delay in early-stage oral squamous cell carcinoma and its relation to survival. Journal of Cranio-Maxillofacial Surgery, 49(6), 462–467. https://doi.org/https://doi.org/10.1016/j.jcms.2021.02.007

Palmerín-Donoso, Alba, Ana Margarita Cantero-Macedo, and Manuel Tejero-Mas. 2020. “Oral leukoplakia TT Leucoplasia oral.” Atencion primaria

(1):59–60.

Pereda Rojas, M. E., González Cardona, Y., & Torres Herrera, L. W. (2016). Actualización sobre liquen plano bucal. Correo Científico Médico, 20(3), 539–555.

Pereira, A., Shitsuka, D., Parreira, F., & Shitsuka, R. (2018). Método Qualitativo, Quantitativo ou Quali-Quanti. In Metodologia da Pesquisa Científica. https://repositorio.ufsm.br/bitstream/handle/1/15824/Lic_Computacao_Metodologia-Pesquisa-Cientifica.pdf?sequence=1. Acesso em: 28 março 2020.

Queiroz, S. I. M. L., De Medeiros, A. M. C., Silva, J. S. P. Da, & Silveira, É. J. D. Da. (2014). Clinical and histopathological evaluation and habits associated with the onset of oral leukoplakia and erythroplakia. Jornal Brasileiro de Patologia e Medicina Laboratorial, 50(2), 144–149. https://doi.org/10.5935/1676-2444.20140008

Ramos, Ruth Tramontani, Camilla Rodrigues Paiva, Andreza Maria De Oliveira Filgueiras, Geraldo Oliveira Silva Junior, Marília Heffer Cantisano, Dennis

De Carvalho Ferreira, and Marcia Ribeiro. 2017. “Leucoplasia Oral: Conceitos e Repercussões Clínicas.” Revista Brasileira de Odontologia 74(1):51.

Tannure, P. N., Barcelos, R., Carolina, M., & Carnasciali, G. (2012). |Eritroplasia bucal: aspectos de interesse ao cirurgião-dentista. Revista Brasileira de Pesquisa Em Saúde/Brazilian Journal of Health Research, 0(0), 94–97. https://doi.org/10.21722/rbps.v0i0.3414

Varela-Centelles, P., Seoane-Romero, J., García-Pola, M. J., Leira-Feijoo, Y., & Seoane-Romero, J. M. (2020). Therapeutic approaches for actinic cheilitis: therapeutic efficacy and malignant transformation after treatment. International Journal of Oral and Maxillofacial Surgery, 49(10), 1343–1350. https://doi.org/https://doi.org/10.1016/j.ijom.2020.02.014

Published

27/08/2021

How to Cite

BINDA, N. C. .; BINDA , A. L. C. .; PINHO , R. A. de; RAMALHO, M. A. .; LEÃO, G. C.; GIRARD, B. P.; SILVA, R. B.; SILVA, . M. K. G. da; FERNANDES, N. D. L.; FERNANDES, J. D. L.; SOUSA, Z. da S.; MONTEIRO, M. S.; COÊLHO, L. P. I.; BARROS, L. S. de A.; MOREIRA , T. P. C.; COSTA, A. M.; LEÃO , M. J. da R. . Potentially malignant lesions of the maxillofacial region. Research, Society and Development, [S. l.], v. 10, n. 11, p. e185101119452, 2021. DOI: 10.33448/rsd-v10i11.19452. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/19452. Acesso em: 16 apr. 2024.

Issue

Section

Health Sciences