Effects of photobiomodulation (low-intensity laser) on wound healing: an integrative review
DOI:
https://doi.org/10.33448/rsd-v10i11.19821Keywords:
Photobiomodulation; Nursing care; Wound healing; Clinical protocols; Laser therapy.Abstract
Objectives: To identify and analyze the existing evidence regarding the use of low-intensity light therapy in wound healing. Method: Integrative review based on the Ganong framework, with a search conducted in March 2020, with a period from January 2015 to March 2020. Results: 15 studies were selected, with different research designs. There was a difference in the parameters used with energies ranging from 1 to 20 J, the wavelength between 632.8 and 940 nm and power from 1.08 mW to 6W. Conclusions: There is no established clinical protocol for wound healing using low intensity light therapy; it is observed that there are beneficial effects of photobiomodulation with adequate wavelength, energy density and power of the device. Further studies are needed to better understand this therapy and establish clinical protocols in health practice.
References
Atasoy, K. T., Korkmaz, Y. T., Odaci, E., & Hanci, H. (2017). The efficacy of low-level 940 nm laser therapy with different energy intensities on bone healing. Brazilian oral research, 31, e7. https://doi.org/10.1590/1807-3107BOR-2017.vol31.0007
Barbosa, L. S, Parisi, J. R., Viana, L. C., Carneiro, M. B., Silva, J. R. T., Silva, M. L., Novaes, R. D. & Sousa. L. (2020). The photobiomodulation (658, 830 and 904nm) on wound healing in histomorphometric analysis. Fisioter mov 33: e003318. https://doi.org/10.1590/1980-5918.033.ao18
Beheregaray, W. K., Gianotti, G. C., Oliveira, F., Terraciano, P., Bianchi, S., Vidor, C. F., Marcolan, E. A., Contesini, E. O. & Cirne, L. (2017). Mesenchymal stem cells applied to the inflammatory and proliferative phases of wound healing Arq bras med vet zootec, 69(6), 1591-600. https://doi.org/10.1590/1678-4162-9461
Carvalho, A. F., Feitosa, M. C., Coelho, N. P., Rebêlo, V. C., Castro, J. G., Sousa, P. R., Feitosa, V. C., & Arisawa, E. A. (2016). Low-level laser therapy and Calendula officinalis in repairing diabetic foot ulcers. Revista da Escola de Enfermagem da U S P, 50(4), 628–634. https://doi.org/10.1590/S0080-623420160000500013
Chung, H., Dai, T., Sharma, S. K., Huang, Y. Y., Carroll, J. D., & Hamblin, M. R. (2012). The nuts and bolts of low-level laser (light) therapy. Annals of biomedical engineering, 40(2), 516–533. https://doi.org/10.1007/s10439-011-0454-7
Chamusca, F. V., Reis, S. R. A., Lemaire, D. & Medrado, A. P. (2012). Mediators of the systemic effects of inflammation and photobiomodulatory therapies: a literature review. R. Ci. Med. Biol, 11(1), 70-78. http://dx.doi.org/10.9771/cmbio.v11i1.5705
Cunha, J., Carvalho, F., Pereira Filho, R. N., Ribeiro, M., & de Albuquerque-Júnior, R. (2019). Effects of Different Protocols of Low-Level Laser Therapy on Collagen Deposition in Wound Healing. Brazilian dental journal, 30(4), 317–324. https://doi.org/10.1590/0103-6440201902400
Da Costa Santos, C. M., de Mattos Pimenta, C. A., & Nobre, M. R. (2007). The PICO strategy for the research question construction and evidence search. Revista latino-americana de enfermagem, 15(3), 508–511. https://doi.org/10.1590/s0104-11692007000300023
De Sousa, A., da Rocha, Í., de Carvalho, A., de Freitas Coelho, N., Feitosa, M., Barros, E., Arisawa, E., & de Amorim, M. (2018). Comparative Study Between Low Level Laser and Therapeutic Ultrasound in Second Intention Ulcers Repair in Mice. Journal of lasers in medical sciences, 9(2), 134–138. https://doi.org/10.15171/jlms.2018.25
Feitosa, M. C., Carvalho, A. F., Feitosa, V. C., Coelho, I. M., Oliveira, R. A., & Arisawa, E. Â. (2015). Effects of the Low-Level Laser Therapy (LLLT) in the process of healing diabetic foot ulcers. Acta cirurgica brasileira, 30(12), 852–857. https://doi.org/10.1590/S0102-865020150120000010
Firouzi, A., Norozian, M., Amini, A., Abdollahifar, M. A., Abbaszadeh, H. A., & Fadaei Fathabadi, F. (2018). Combined Effect of Low-Level Laser Treatment and Levothyroxine on Wound Healing in Rats With Hypothyroidism. Journal of lasers in medical sciences, 9(4), 268–273. https://doi.org/10.15171/jlms.2018.48
Filho, N. R., Ferreira, M., Pascoli, A., Viéra, R., Pazzini, J., Oliveira R, Salardani, P., Silva, L., Rosseto, S., Albernaz, R.O., Vasconcelos, A., Ferraudo, P.C. & Moraes, A. (2017). Skin graft epithelialization in rabbit fresh wounds treated with amniotic membrane and/or laser therapy. Arq bras med vet zootec, 69(3), 603-612. https://doi.org/10.1590/1678-4162-9337
Ganong L. H. (1987). Integrative reviews of nursing research. Research in nursing & health, 10(1), 1–11. https://doi.org/10.1002/nur.4770100103
Gomes, C. F. & Schapochnik, A. (2017). The therapeutic use of low intensity laser (LLLT) in some diseases and its relation to the performance in speech therapy. Distúrb comun, 29(3), 570-578. http://dx.doi.og/10.23925/2176-2724.2017v29i3p570-578
Gomes, M. T., Campos, G. R., Piccolo N., França, C. M., Guedes, G. H., Lopes, F., Renata, A., Belotto, R. A., Pavani, C., Lima, R. N. & Silva, D. F. T. (2017). Experimental burns: Comparison between silver sulfadiazine and photobiomodulation. Rev Assoc Med Bras, 63(1), 29-34. https://doi.org/10.1590/1806-9282.63.01.29
Kazemikhoo, N., Vaghardoost, R., Dahmardehei, M., Mokmeli, S., Momeni, M., Nilforoushzadeh, M. A., Ansari, F., Razagi, M. R., Razagi, Z., Amirkhani, M. A., & Masjedi, M. R. (2018). Evaluation of the Effects of Low Level Laser Therapy on the Healing Process After Skin Graft Surgery in Burned Patients (A Randomized Clinical Trial). Journal of lasers in medical sciences, 9(2), 139–143. https://doi.org/10.15171/jlms.2018.26
Lima, N. E. P., Gomes, G. M., Feitosa, A. N. A., Bezerra, A. L. D. & Sousa, M. N. A.(2018). Laser therapy low intensity in wound care and practice nurses. Rev enferm UFPI. 7(1),50-56. https://doi.org/10.26694/2238-7234.7150-56
Martelli, A., Andrade, T. A. M. de, & Santos, G. M. T. dos. (2018). Perspectivas na utilização de fitoterápicos na cicatrização tecidual: revisão sistemática. Archives Of Health Investigation, 7(8). https://doi.org/10.21270/archi.v7i8.3047
Martins, S. S., Torres, O. J. M., Santos, O. J., Limeira, F. A. Jr., Sauaia Filho, E. N, Melo, S. P. C., Pinheiro, R. P. S. & Silva, B. S. (2015). Analysis of the healing process of the wounds occurring in rats using lasertherapy in association with hydrocolloid. Acta. cir. Bras, 30(10), 681-685. https://doi.org/10.1590/S0102-865020150100000005
Medeiros, A. C., & Dantas-Filho, A. M. (2017). Cicatrização das feridas cirúrgicas. Journal Of Surgical And Clinical Research, 7(2), 87-102. https://doi.org/10.20398/jscr.v7i2.11438
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & PRISMA Group (2009). Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS medicine, 6(7), e1000097. https://doi.org/10.1371/journal.pmed.1000097
Nilforoushzadeh, M. A., Kazemikhoo, N., Mokmeli, S., Zare, S., Dahmardehei, M., Vaghar Doost, R., Momeni, M., & Ansari, F. (2019). An Open-Label Study of Low-Level Laser Therapy Followed by Autologous Fibroblast Transplantation for Healing Grade 3 Burn Wounds in Diabetic Patients. Journal of lasers in medical sciences, 10(Suppl 1), S7–S12. https://doi.org/10.15171/jlms.2019.S2
Oliveira, I. V. P. & Dias, R. V. C. (2012). Cicatrização de feridas: fases e fatores de influência. Acta Veterinaria Brasílica, 6(4), 267-271. https://doi.org/10.21708/avb.2012.6.4.2959
Scherer, N. H. B., Silva, A. M. V., Gutierres, J., Veloso, C. F., Pinfildi, C. E. & Gobbato, R. C. (2019). Laser Photobiomodulation in the acute inflammatory response of the calcaneal tendon injury in rats exposed to cigarette smoke. Fisioter Pesqui, 26(2), 164-169. https://doi.org/10.1590/1809-2950/18032726022019
Silva Neto, C. P., Freire Jr, O. (2017). A gift from Apollo: lasers, history, applications. Rev Bras Ens Fis, 39(1), e1502. https://doi.org/10.1590/1806-9126-RBEF-2016-0152
Szwed, D. N. & Santos, V. L. P. (2016). Growth factors involved in skin healing. Cad da Esc de Saúde.1 (15), 7-17. https://portaldeperiodicos.unibra sil.com.br/index.php/cadernossaude/article/view/2450/2020
Souza, M. T., Silva, M. D., & Carvalho, R. d. (2010). Integrative review: what is it? How to do it? Einstein (Sao Paulo, Brazil), 8(1), 102–106. https://doi.org/10.1590/S1679-45082010RW1134
Tacani, P. M., Tacani, R. E., Machado, A., Montezello, D., Góes, J., Marx, A. G., & Liebano, R. E. (2018). High-Frequency Generator in Wound Healing of Marjolin's Ulcer After Carcinoma Resection. Advances in wound care, 7(5), 165–170. https://doi.org/10.1089/wound.2017.0757
Taradaj, J., Shay, B., Dymarek, R., Sopel, M., Walewicz, K., Beeckman, D., Schoonhoven, L., Gefen, A., & Rosińczuk, J. (2018). Effect of laser therapy on expression of angio- and fibrogenic factors, and cytokine concentrations during the healing process of human pressure ulcers. International journal of medical sciences, 15(11), 1105–1112. https://doi.org/10.7150/ijms.25651
Ursi, E. S., & Gavão, C. M. (2006). Prevenção de lesões de pele no perioperatório: revisão integrativa da literatura [Perioperative prevention of skin injury: an integrative literature review]. Revista latino-americana de enfermagem, 14(1), 124–131. https://doi.org/10.1590/s0104-11692006000100017
Vieira, R. Q., Sanchez, B. C. S., Fernandes, R. P., Dias, T. N., Aquino, U. M. & Santos, A. E. (2017). First writings on nursing care in wounds and dressings in Brazil (1916-1947). Hist enferm Rev electronica, 8(2), 106-117. http://here.abennacional.org.br/here/v8/n2/a05.pdf
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2021 Karina Alexandra Batista da Silva Freitas; Eliana Maria Minicucci; Talita Oliveira de Lima; Karen Aline Batista da Silva; Benedito Donizete Menozzi; Valéria Flávia Batista da Silva; Regina Célia Popim
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
