Yerba mate (Ilex paraguariensis A. St. – hil.): a comprehensive review on chemical composition, health benefits and recent advances

Authors

DOI:

https://doi.org/10.33448/rsd-v10i11.20036

Keywords:

Ilex paraguariensis; Yerba mate; Polyphenols; Anti-oxidant; Antimicrobial.

Abstract

Chimarrão is a typical drink from the southern region of Brazil and produced from the leaves and branches of Ilex paraguariensis that will form the yerba mate. The purpose of this review is to provide a concise summary of research published in the last 10 years with an emphasis on the Ilex paraguariensis species, its general characteristics, chemical composition and its main health benefits. This study is an exploratory descriptive literature review regarding the biological activity and pharmacological action of the plant Ilex paraguariensis A. St. - Hill. The Scientific Electronic Library Online (Scielo), National Library of Medicine (Pubmed), Scopus and Academic Google databases were used for research. The main chemical compounds identified in the yerba mate extract are: polyphenols (chlorogenic acid) and xanthines (caffeine and theobromine). Among the potentially beneficial effects on human health are activities such as: antioxidant, anti-inflammatory, antimicrobial, anti-obesity, anti-diabetic, neuroprotective, cardiovascular protection, regulation of the intestinal microbiota and anti-cancer. Therefore, beverages produced from Ilex paraguariensis have great potential as a source of biological compounds for the pharmaceutical and nutraceutical industry.

References

Abbas, A. K., Fausto, N., Mitchell, R. N., & Kumar, V. (2008). Robbins patologia básica. Elsevier Brasil.

Afonso, M. A., Bonapaz, L. D. S., Dutra, M. S., Diel, V. B. N., Francescato, L. N., & Velho, R. V. (2017). Avaliação da atividade antimicrobiana do óleo volátil e extratos etanólicos de folhas e ramos de ilex paraguariensis a. St.-hil. (erva-mate). Revista de ciências ambientais, 11(3), 33-40.

Antunes, A., Cardoso, D. S., & da Silva Paula, C. (2017). Efeito da Ilex paraguariensis a. St. Hil.(Erva Mate) no controle da obesidade. Visão Acadêmica, 18(1).

Arçari, D. P., Porto, V. B., Rodrigues, E. R. V., Martins, F., de Lima, R. J., Sawaya, A. C. H. F., ... & de Oliveira Carvalho, P. (2011). Effect of mate tea (Ilex paraguariensis) supplementation on oxidative stress biomarkers and LDL oxidisability in normo-and hyperlipidaemic humans. Journal of Functional Foods, 3(3), 190-197.

Baeza, G., Sarriá, B., Mateos, R., & Bravo, L. (2016). Dihydrocaffeic acid, a major microbial metabolite of chlorogenic acids, shows similar protective effect than a yerba mate phenolic extract against oxidative stress in HepG2 cells. Food Research International, 87, 25-33.

Balzan, S., Hernandes, A., Reichert, C. L., Donaduzzi, C., Pires, V. A., Junior, A. G., & Junior, E. L. C. (2013). Lipid-lowering effects of standardized extracts of Ilex paraguariensis in high-fat-diet rats. Fitoterapia, 86, 115-122.

Barboza, L. M. V. (2006). Desenvolvimento de bebida à base de erva-mate (Ilex paraguariensis Saint Hilaire) adicionada de fibra alimentar.

Barg, M., Rezin, G. T., Leffa, D. D., Balbinot, F., Gomes, L. M., Carvalho-Silva, M., & Andrade, V. M. (2014). Evaluation of the protective effect of Ilex paraguariensis and Camellia sinensis extracts on the prevention of oxidative damage caused by ultraviolet radiation. Environmental toxicology and pharmacology, 37(1), 195-201.

Bastos, D. H. M., & Torres, E. A. F. D. S. (2003). Bebidas a base de erva-mate (Ilex paraguariensis) e saúde pública. Nutrire Rev. Soc. Bras. Aliment. Nutr, 77-89.

Bastos, D. H. M., Ishimoto, E. Y., Marques, M. O. M., Ferri, A. F., & Torres, E. A. (2006). Essential oil and antioxidant activity of green mate and mate tea (Ilex paraguariensis) infusions. Journal of Food Composition and Analysis, 19(6-7), 538-543.

Bastos, D. H., Fornari, A. C., Queiroz, Y. S., & Torres, E. A. (2006). Bioactive compounds content of chimarrão infusions related to the moisture of yerba maté (Ilex paraguariensis) leaves. Brazilian archives of biology and technology, 49, 399-404.

Bates, M. N., Hopenhayn, C., Rey, O. A., & Moore, L. E. (2007). Bladder cancer and mate consumption in Argentina: a case-control study. Cancer letters, 246(1-2), 268-273.

Berkai, D., & Braga, C. A. (2000). 500 anos de história da erva-mate. Editora Cone Sul.

Berté, K. A., Beux, M. R., Spada, P. K., Salvador, M., & Hoffmann-Ribani, R. (2011). Chemical composition and antioxidant activity of yerba-mate (Ilex paraguariensis A. St.-Hil., Aquifoliaceae) extract as obtained by spray drying. Journal of Agricultural and Food Chemistry, 59(10), 5523-5527.

Boaventura, B. C. B., da Silva, E. L., Liu, R. H., Prudêncio, E. S., Di Pietro, P. F., Becker, A. M., & Amboni, R. D. D. M. C. (2015). Effect of yerba mate (Ilex paraguariensis A. St. Hil.) infusion obtained by freeze concentration technology on antioxidant status of healthy individuals. LWT-Food Science and Technology, 62(2), 948-954.

Boaventura, B. C. B., Di Pietro, P. F., Klein, G. A., Stefanuto, A., de Morais, E. C., de Andrade, F., & da Silva, E. L. (2013). Antioxidant potential of mate tea (Ilex paraguariensis) in type 2 diabetic mellitus and pre-diabetic individuals. Journal of Functional Foods, 5(3), 1057-1064.

Boaventura, B. C. B., Di Pietro, P. F., Stefanuto, A., Klein, G. A., de Morais, E. C., de Andrade, F., & da Silva, E. L. (2012). Association of mate tea (Ilex paraguariensis) intake and dietary intervention and effects on oxidative stress biomarkers of dyslipidemic subjects. Nutrition, 28(6), 657-664.

Bojić, M., Simon Haas, V., Šarić, D., & Maleš, Ž. (2013). Determination of flavonoids, phenolic acids, and xanthines in mate tea (Ilex paraguariensis St.-Hil.). Journal of analytical methods in Chemistry, 2013.

Bortoli, P. M., Alves, C., Costa, E., Vanin, A. P., Sofiatti, J. R., Siqueira, D. P., & Kaizer, R. R. (2018). Ilex paraguariensis: Potential antioxidant on aluminium toxicity, in an experimental model of Alzheimer's disease. Journal of inorganic biochemistry, 181, 104-110.

Bracesco, N., Sanchez, A. G., Contreras, V., Menini, T., & Gugliucci, A. (2011). Recent advances on Ilex paraguariensis research: minireview. Journal of ethnopharmacology, 136(3), 378-384.

Burris, K. P., Davidson, P. M., Stewart Jr, C. N., Zivanovic, S., & Harte, F. M. (2012). Aqueous extracts of yerba mate (Ilex paraguariensis) as a natural antimicrobial against Escherichia coli O157: H7 in a microbiological medium and pH 6.0 apple juice. Journal of food protection, 75(4), 753-757.

Burris, K. P., Davidson, P. M., Stewart, Jr, C. N., & Harte, F. M. (2011). Antimicrobial activity of yerba mate (Ilex paraguariensis) aqueous extracts against Escherichia coli O157: H7 and Staphylococcus aureus. Journal of Food Science, 76(6), M456-M462.

Carelli, G., Macedo, S. M. D., Valduga, A. T., Corazza, M. L., Oliveira, J. V., Franceschi, E., & Jaskulski, M. R. (2011). Avaliação preliminar da atividade antimicrobiana do extrato de erva-mate (Ilex paraguariensis A. St.-Hil.) obtido por extração com CO2 supercrítico. Revista Brasileira de Plantas Medicinais, 13, 110-115.

Coelho, G. C., Rachwal, M. F., Dedecek, R. A., Curcio, G. R., Nietsche, K., & Schenkel, E. P. (2007). Effect of light intensity on methylxanthine contents of Ilex paraguariensis A. St. Hil. Biochemical systematics and ecology, 35(2), 75-80.

Contreras, P. D. (2007). Desenvolvimento de bebida à base de subprodutos da indústria da erva-mate (Ilex paraguariensis St. Hil.) e verificação de sua atividade antioxidante.

Costa, D. E. M., Racanicci, A. M. C., & Santana, Â. P. (2017). Atividade antimicrobiana da erva-mate (Ilex paraguariensis) contra microrganismos isolados da carne de frango. Ciência Animal Brasileira, 18.

Da Croce, D. M. (2000). Cadeias produtivas do Estado de Santa Catarina: erva-mate. Epagri.

da Silva Brasilino, M., Pereira, A. A. F., Zepponi, K. M. C., Neto, A. H. C., de Carvalho, A. A. F., & Nakamune, A. C. D. M. S. (2013). Erva mate minimiza as alterações do perfil lipídico promovidas por elevado consumo de sacarose. Archives of Health Investigation, 2(5).

da Silveira, T. F. F., Meinhart, A. D., Coutinho, J. P., de Souza, T. C. L., Cunha, E. C. E., de Moraes, M. R., & Godoy, H. T. (2016). Content of lutein in aqueous extracts of yerba mate (Ilex paraguariensis St. Hil). Food Research International, 82, 165-171.

Daniel, O. (2009). Erva-mate: sistema de produção e processamento industrial. Universidade Federal da Grande Dourados.

De Biasi, B., Grazziotin, N. A., & Hofmann Jr, A. E. (2009). Atividade antimicrobiana dos extratos de folhas e ramos da Ilex paraguariensis A. St.-Hil., Aquifoliaceae. Revista Brasileira de Farmacognosia, 19, 582-585.

De Bona, E. D. A. M., da Silva Pinto, F. G., Borges, A. M. C., Weber, L. D., Fruet, T. K., Alves, L. F. A., & de Moura, A. C. (2010). Avaliação da atividade antimicrobiana de erva-Mate (Ilex paraguariensis) sobre sorovares de Salmonella spp. de origem avícola. Journal of Health Sciences, 12(3).

De Morais, E. C., Stefanuto, A., Klein, G. A., Boaventura, B. C., De Andrade, F., Wazlawik, E., & da Silva, E. L. (2009). Consumption of yerba mate (Ilex paraguariensis) improves serum lipid parameters in healthy dyslipidemic subjects and provides an additional LDL-cholesterol reduction in individuals on statin therapy. Journal of Agricultural and Food Chemistry, 57(18), 8316-8324.

De Oliveira, E. P., Torezan, G. A., de Souza Gonçalves, L., Corrente, J. E., McLellan, K. C. P., & Burini, R. C. (2016). O consumo agudo de erva mate aumenta o gasto energético de homens jovens saudáveis-um estudo piloto. RBONE-Revista Brasileira de Obesidade, Nutrição e Emagrecimento, 10(59), 242-249.

De Oliveira, E., Lima, N. S., Conceição, E. P. S., Peixoto-Silva, N., Moura, E. G., & Lisboa, P. C. (2018). Treatment with Ilex paraguariensis (yerba mate) aqueous solution prevents hepatic redox imbalance, elevated triglycerides, and microsteatosis in overweight adult rats that were precociously weaned. Brazilian Journal of Medical and Biological Research, 51(6).

de Resende, M. D. V., Sturion, J. A., de Carvalho, A. P., Simeão, R. M., & Fernandes, J. S. C. (2000). Programa de melhoramento da erva-mate coordenado pela EMBRAPA: resultados da avaliação genética de populações, progênies, indivíduos e clones. Embrapa Florestas-Circular Técnica (INFOTECA-E).

Deladino, L., Anbinder, P. S., Navarro, A. S., & Martino, M. N. (2008). Encapsulation of natural antioxidants extracted from Ilex paraguariensis. Carbohydrate polymers, 71(1), 126-134.

Fagundes, A., Schmitt, V., Danguy, L. B., & Mazur, C. E. (2015). Ilex Paraguariensis: composto bioativos e propriedades nutricionais na saúde. RBONE-Revista Brasileira de Obesidade, Nutrição e Emagrecimento, 9(53), 213-222.

Gambero, A., & Ribeiro, M. L. (2015). The positive effects of yerba maté (Ilex paraguariensis) in obesity. Nutrients, 7(2), 730-750.

Gan, R. Y., Zhang, D., Wang, M., & Corke, H. (2018). Health benefits of bioactive compounds from the genus Ilex, a source of traditional caffeinated beverages. Nutrients, 10(11), 1682.

Giberti, G. C. (1995). Ilex en Sudamérica: Florística, sistemática y potencialidades con relación a un banco de germoplasma para la yerba mate. Erva-Mate: Biología e Cultura no Cono Sul. H. Winge, AG Ferreira, JE de Araujo Mariíta and L. Tarasconi, Eds. UFRGS, Brazil, 303-312.

Goldenberg, D., Golz, A., & Joachims, H. Z. (2003). The beverage mate: a risk factor for cancer of the head and neck. Head & Neck: Journal for the Sciences and Specialties of the Head and Neck, 25(7), 595-601.

Heinrichs, R., & Malavolta, E. (2001). Composição mineral do produto comercial da erva-mate (Ilex paraguariensis St. Hil.). Ciência Rural, 31, 781-785.

Hussein, G. M., Matsuda, H., Nakamura, S., Akiyama, T., Tamura, K., & Yoshikawa, M. (2011). Protective and ameliorative effects of maté (Ilex paraguariensis) on metabolic syndrome in TSOD mice. Phytomedicine, 19(1), 88-97.

Isolabella, S., Cogoi, L., López, P., Anesini, C., Ferraro, G., & Filip, R. (2010). Study of the bioactive compounds variation during yerba mate (Ilex paraguariensis) processing. Food Chemistry, 122(3), 695-699.

Isolabella, S., Cogoi, L., López, P., Anesini, C., Ferraro, G., & Filip, R. (2010). Study of the bioactive compounds variation during yerba mate (Ilex paraguariensis) processing. Food Chemistry, 122(3), 695-699.

Kang, Y. R., Lee, H. Y., Kim, J. H., Moon, D. I., Seo, M. Y., Park, S. H., & Oh, H. G. (2012). Anti-obesity and anti-diabetic effects of Yerba Mate (Ilex paraguariensis) in C57BL/6J mice fed a high-fat diet. Laboratory animal research, 28(1), 23-29.

Kim, S. Y., Oh, M. R., Kim, M. G., Chae, H. J., & Chae, S. W. (2015). Anti-obesity effects of Yerba Mate (Ilex Paraguariensis): a randomized, double-blind, placebo-controlled clinical trial. BMC complementary and alternative medicine, 15(1), 1-8.

Lima, N. D. S., Franco, J. G., Peixoto-Silva, N., Maia, L. A., Kaezer, A., Felzenszwalb, I., & Lisboa, P. C. (2014). Ilex paraguariensis (yerba mate) improves endocrine and metabolic disorders in obese rats primed by early weaning. European journal of nutrition, 53(1), 73-82.

Luz, A. B. G., da Silva, C. H. B., Nascimento, M. V. P., de Campos Facchin, B. M., Baratto, B., Fröde, T. S., & Dalmarco, E. M. (2016). The anti-inflammatory effect of Ilex paraguariensis A. St. Hil (Mate) in a murine model of pleurisy. International immunopharmacology, 36, 165-172.

Maccari Junior, A. (2005). Análise do pré-processamento da erva-mate para chimarrão.

Machado, C. C. B., Bastos, D. H. M., Janzantti, N. S., Facanali, R., Marques, M. O. M., & Franco, M. R. B. (2007). Determinação do perfil de compostos voláteis e avaliação do sabor e aroma de bebidas produzidas a partir da erva-mate (Ilex paraguariensis). Química nova, 30, 513-518.

Martin, J. G. P., Porto, E., de Alencar, S. M., da Glória, E. M., Corrêa, C. B., & Cabral, I. S. R. (2013). Antimicrobial activity of yerba mate (Ilex paraguariensis St. Hil.) against food pathogens. Revista Argentina de microbiologia, 45(2), 93-98.

Mateos, R., Baeza, G., Sarriá, B., & Bravo, L. (2018). Improved LC-MSn characterization of hydroxycinnamic acid derivatives and flavonols in different commercial mate (Ilex paraguariensis) brands. Quantification of polyphenols, methylxanthines, and antioxidant activity. Food chemistry, 241, 232-241.

Mazuchowski, J. Z., & Empresa Paranaense de Assistência Técnica e Extensão Rural. (1991). Manual da erva-mate (Ilex paraguariensis St. Hill.). EMATER/PR.

Medrado, M. J. S., & Mosele, S. H. (2004). O futuro da investigação científica em erva-mate. Embrapa Florestas-Documentos (INFOTECA-E).

Meinhart, A. D., Bizzotto, C. S., Ballus, C. A., Poloni Rybka, A. C., Sobrinho, M. R., Cerro-Quintana, R. S., & Godoy, H. T. (2010). Methylxanthines and phenolics content extracted during the consumption of mate (Ilex paraguariensis St. Hil) beverages. Journal of Agricultural and Food Chemistry, 58(4), 2188-2193.

Mendes, F. R., & Carlini, E. A. (2007). Brazilian plants as possible adaptogens: an ethnopharmacological survey of books edited in Brazil. Journal of Ethnopharmacology, 109(3), 493-500.

Molin, R. F., Dartora, N., Borges, A. C. P., Gonçalves, I. L., Di Luccio, M., & Valduga, A. T. (2014). Total phenolic contents and antioxidant activity in oxidized leaves of mate (Ilex paraguariensis St. Hil). Brazilian Archives of Biology and Technology, 57, 997-1003.

Muñoz-Culla, M., Sáenz-Cuesta, M., Guereca-Barandiaran, M. J., Ribeiro, M. L., & Otaegui, D. (2016). Yerba mate (Ilex paraguariensis) inhibits lymphocyte activation in vitro. Food & function, 7(11), 4556-4563.

Noureddine, T., El Husseini, Z., Nehme, A., & Massih, R. A. (2018). Antibacterial activity of Ilex paraguariensis (Yerba Mate) against Gram-positive and Gram-negative bacteria. The Journal of Infection in Developing Countries, 12(09), 712-719.

Pagliosa, C. M. (2012). Caracterização química do resíduo de ervais e folhas" in natura" de erva-mate (Ilex paraguariensis A. St. Hil.).

Pereira, A. A. F., Tirapeli, K. G., Chaves-Neto, A. H., da Silva Brasilino, M., da Rocha, C. Q., Belló-Klein, A., & Nakamune, A. C. D. M. S. (2017). Ilex paraguariensis supplementation may be an effective nutritional approach to modulate oxidative stress during perimenopause. Experimental gerontology, 90, 14-18.

Petrilli, A. A., Souza, S. J., Teixeira, A. M., Pontilho, P. M., Souza, J. M., Luzia, L. A., & Rondó, P. H. (2016). Effect of chocolate and yerba mate phenolic compounds on inflammatory and oxidative biomarkers in HIV/AIDS individuals. Nutrients, 8(5), 132.

Pimentel, G. D., Lira, F. S., Rosa, J. C., Caris, A. V., Pinheiro, F., Ribeiro, E. B., & Oyama, L. M. (2013). Yerba mate extract (Ilex paraguariensis) attenuates both central and peripheral inflammatory effects of diet-induced obesity in rats. The Journal of nutritional biochemistry, 24(5), 809-818.

Pomilio, A. B., Trajtemberg, S., & Vitale, A. A. (2002). High‐Performance Capillary Electrophoresis Analysis of mate infusions prepared from stems and leaves of Ilex paraguariensis using Automated Micellar Electrokinetic Capillary Chromatography. Phytochemical Analysis: An International Journal of Plant Chemical and Biochemical Techniques, 13(4), 235-241.

Przygodda, F., Martins, Z. N., Castaldelli, A. P. A., Minella, T. V., Vieira, L. P., Cantelli, K., & Padoin, M. J. (2010). Effect of erva-mate (Ilex paraguariensis A. St.-Hil., Aquifoliaceae) on serum cholesterol, triacylglycerides and glucose in Wistar rats fed a diet supplemented with fat and sugar. Revista Brasileira de Farmacognosia, 20, 956-961.

Puangpraphant, S., Berhow, M. A., & De Mejia, E. (2012). Yerba Mate (Ilex Paraguariensis St. Hilaire) saponins inhibit human colon cancer cell proliferation. In Hispanic Foods: Chemistry and Bioactive Compounds (pp. 307-321). American Chemical Society.

Racanicci, A. M., Danielsen, B., & Skibsted, L. H. (2008). Mate (Ilex paraguariensis) as a source of water extractable antioxidant for use in chicken meat. European Food Research and Technology, 227(1), 255-260.

Ramirez-Mares, M. V., Chandra, S., & De Mejia, E. G. (2004). In vitro chemopreventive activity of Camellia sinensis, Ilex paraguariensis and Ardisia compressa tea extracts and selected polyphenols. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 554(1-2), 53-65.

Rempe, C. S., Lenaghan, S. C., Burris, K. P., & Stewart, C. N. (2017). Metabolomic analysis of the mechanism of action of yerba mate aqueous extract on Salmonella enterica serovar Typhimurium. Metabolomics, 13(2), 16.

Rocha Junior, W. F. D. (2001). Análise do Agronegócio da Erva-Mate com o enfoque da Nova Economia Institucional e o uso da matriz estrutural prospectiva.

Rodríguez-Arzuaga, M., & Piagentini, A. M. (2018). New antioxidant treatment with yerba mate (Ilex paraguariensis) infusion for fresh-cut apples: Modeling, optimization, and acceptability. Food Science and Technology International, 24(3), 223-231.

SAINT-HILAIRE, A. Histoire des Plantes les plus remarquables du Brésil et du Paraguay (1824b). Chez A. Berlin. Imprimer Libraire. Paris.

Scherer, R., Janssens, M. J. J., Marx, F., Urfer, P., & Schneider, E. (2007). Saponin content and quality-related traits of mass-selected yerba maté (Ilex paraguariensis A. St.-Hil.) trees. Journal of herbs, spices & medicinal plants, 12(1-2), 73-85.

Schinella, G., Fantinelli, J. C., & Mosca, S. M. (2005). Cardioprotective effects of Ilex paraguariensis extract: evidence for a nitric oxide-dependent mechanism. Clinical Nutrition, 24(3), 360-366.

Schinella, G., Neyret, E., Cónsole, G., Tournier, H., Prieto, J. M., Ríos, J. L., & Giner, R. M. (2014). An aqueous extract of Ilex paraguariensis reduces carrageenan-induced edema and inhibits the expression of cyclooxygenase-2 and inducible nitric oxide synthase in animal models of inflammation. Planta medica, 80(12), 961-968.

Sewram, V., De Stefani, E., Brennan, P., & Boffetta, P. (2003). Mate consumption and the risk of squamous cell esophageal cancer in Uruguay. Cancer Epidemiology and Prevention Biomarkers, 12(6), 508-513.

Silva, R. D. A., Bueno, A. L. S., Gallon, C. W., Gomes, L. F., Kaiser, S., Pavei, C., & Jahn, M. P. (2011). The effect of aqueous extract of gross and commercial yerba mate (Ilex paraguariensis) on intra-abdominal and epididymal fat and glucose levels in male Wistar rats. Fitoterapia, 82(6), 818-826.

Souza, A. H., Corrêa, R. C., Barros, L., Calhelha, R. C., Santos-Buelga, C., Peralta, R. M., & Ferreira, I. C. (2015). Phytochemicals and bioactive properties of Ilex paraguariensis: An in-vitro comparative study between the whole plant, leaves and stems. Food Research International, 78, 286-294.

Toniazzo, G., Camel, M., Becegatto, M., Valduga, A., Cichoski, A., Valduga, E., & Oliveira, D. D. (2013). Influência do potencial antioxidante de extrato de erva-mate (ilex paraguariensis st. hil) em frango assado, armazenado e reaquecido* Infl uence of antioxidant potential of mate leaves extract (Ilex paraguariensis St. Hil) in cooked, stored. Alimentos e Nutrição Araraquara, 23(2), 297-305.

Valduga, A. T., Battestin, V., & Finzer, J. R. D. (2003). Secagem de extratos de erva-mate em secador por atomização. Food Science and Technology, 23, 184-189.

Valduga, E. (1995). Caracterização química e anatômica da folha de (Ilex paraguariensis St. Hil) e de algumas espécies utilizadas na adulteração do mate. 1995. 97p (Doctoral dissertation, Dissertação (Mestrado)–Universidade Federal do Paraná, Curitiba).

Vieira, M. A., Rovaris, A. A., Maraschin, M., De Simas, K. N., Pagliosa, C. M., Podestá, R., ... & Amante, E. R. (2008). Chemical characterization of candy made of erva-mate (Ilex paraguariensis A. St. Hil.) residue. Journal of agricultural and food chemistry, 56(12), 4637-4642.

Yonny, M. E., Medina, A. V., Nazareno, M. A., & Chaillou, L. L. (2018). Enhancement in the oxidative stability of green peas by Ilex paraguariensis addition in a blanching process before their refrigerated and frozen storage. LWT, 91, 315-321.

Zwyrzykowska, A.; Kupczynski, R.; Jarosz, B.; Szumny, A.; Kucharska, A. Z. (2015). Qualitative and quantitative analysis of polyphenolic compounds in Ilex Sp. Open Chemistry Journal, 1303-1312.

Published

11/09/2021

How to Cite

CARDOZO, A. G. L. .; ROSA, R. L. da; NOVAK, R. S. .; FOLQUITTO, D. G. .; SCHEBELSKI, D. J. .; BRUSAMARELLO, L. C. C. .; RIBEIRO, D. T. B. . Yerba mate (Ilex paraguariensis A. St. – hil.): a comprehensive review on chemical composition, health benefits and recent advances. Research, Society and Development, [S. l.], v. 10, n. 11, p. e590101120036, 2021. DOI: 10.33448/rsd-v10i11.20036. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/20036. Acesso em: 20 apr. 2024.

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Review Article