Maternal clinical findings of sars-cov-2 infection in pregnancy: an integrative review

Authors

DOI:

https://doi.org/10.33448/rsd-v10i12.20188

Keywords:

Coronavirus Infection; Infectious Complications in Pregnant Women; COVID-19.

Abstract

Objective: to describe evidence related to maternal complications during pregnancy due to SARS-COV-2 infection. Method: The search was conducted in Medline databases via Pubmed, Cochrane and Embase via Elsevier, whose search was carried out between March and April 2021. The descriptors used were indexed in the Medical Subject Headings (MeSH) system and in Emtree, namely: Pregnancy Complications, Infectious, COVID-19, SARS-CoV-2, pregnancy complication and coronavirus disease 2019. Articles published in Portuguese, English or Spanish, published between 2019-2021 and full articles with open access via Portal de Periódicos Capes, were included. Duplicate articles, articles focused on other themes, case reports, letter to the editor and review studies were excluded. Initially, 2,809 articles were obtained, being selected according to the following steps: identification, screening and eligibility. 18 articles were included for the synthesis of the final sample. Results: The main complications were spontaneous abortions, thrombocytpnea, perinatal deaths, premature rupture of membranes, premature birth and intrauterine fetal death. Most women were admitted to the ICU and experienced postpartum hemorrhage. There was an increase in emergency cesarean sections, and some suffered from Post Traumatic Stress Disorder, postpartum depression and post-abortion depression. Conclusion: Maternal complications were identified due to contamination by SARS-COV-2.

References

Antoun L., Taweel N. E., Ahmed I., Patni S., & Honest H. (2020). Maternal COVID-19 infection, clinical characteristics, pregnancy, and neonatal outcome: A prospective cohort study. Eur J Obstet Gynecol Reprod Biol, 252:559-562. 10.1016/j.ejogrb.2020.07.008

Andrikopoulou M. et al. (2020). Symptoms and Critical Illness Among Obstetric Patients With Coronavirus Disease 2019 (COVID-19) Infection. Obstet Gynecol, 136(2):291-299. 10.1097/AOG.0000000000003996

Askary E. et al. (2021). Coronavirus disease 2019 (COVID-19) manifestations during pregnancy in all three trimesters: A case series. Int J Reprod Biomed, 19(2):191-204. 10.18502/ijrm.v19i2.8477

Brasil (2016). Diretrizes nacionais de atenção à gestante: operação cesariana. Ministério da Saúde, Secretaria de Ciência, Tecnologia e Insumos Estratégicos, Departamento de Gestão e Incorporação de Tecnologias em Saúde, Brasília, DF.

Chen H. et al. (2020). Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records [published correction appears in Lancet, Mar 28;395(10229):1038], 10.1016/S0140-6736(20)30360-3

Dashraath P. et al. (2020). Coronavirus disease 2019 (COVID-19) pandemic and pregnancy. Am J Obstet Gynecol. 222(6):521-531, 10.1016/j.ajog.2020.03.021

Furlan M. C. R. et al. (2020). Gravidez e infecção por Coronavírus: desfechos maternos, fetais e neonatais – Revisão sistemática. Rev Cuid, Bucaramanga, 11(2), e1211, 10.15649/cuidarte.1211.

Ferrazzi E. et al. (2020). Vaginal delivery in SARS-CoV-2-infected pregnant women in Northern Italy: a retrospective analysis. BJOG, 127(9):1116-1121. 10.1111/1471-0528.16278

Gil, A. C. (2017). Como elaborar projetos de pesquisa. (6a ed.), Atlas.

Hcini N. et al. (2021). Maternal, fetal and neonatal outcomes of large series of SARS-CoV-2 positive pregnancies in peripartum period: A single-center prospective comparative study. Eur J Obstet Gynecol Reprod Biol, 257:11-18. 10.1016/j.ejogrb.2020.11.068

Kayem G. et al. (2020). A snapshot of the Covid-19 pandemic among pregnant women in France. J Gynecol Obstet Hum Reprod, 49(7):101826. 10.1016/j.jogoh.2020.101826

Knight M. et al. (2020). Characteristics and outcomes of pregnant women admitted to hospital with confirmed SARS-CoV-2 infection in UK: national population based cohort study. BMJ. 369:m2107. 10.1136/bmj.m2107

Lokken E. M.et al. (2020). Clinical characteristics of 46 pregnant women with a severe acute respiratory syndrome coronavirus 2 infection in Washington State. Am J Obstet Gynecol, 223(6):911.e1-911.e14. 10.1016/j.ajog.2020.05.031

Ozsurmeli M. et al. (2021). Clinical characteristics, maternal and neonatal outcomes of pregnant women with SARS-CoV-2 infection in Turkey. Bratisl Lek Listy, 122(2):152-157. 10.4149/BLL_2021_023

Ortiz M. E., Hernandez P. R., Pola G. M., & Pascual P. A. (2020). Rodriguez Rodriguez E, Hernandez Martinez A. COVID-19 infection in symptomatic pregnant women at the midpoint of the pandemic in Spain: a retrospective analysis. Ginekol Pol. 91(12):755-763.

Oskovi-Kaplan Z. A., Buyuk G. N., Ozgu-Erdinc A. S., Keskin H. L., Ozbas A., & Moraloglu T. O. (2021). O efeito da pandemia de COVID-19 e restrições sociais nas taxas de depressão e apego materno em mulheres no pós-parto imediato: um estudo preliminar. The Psychiatric quarterly , 92 (2), 675-682. https://doi.org/10.1007/s11126-020-09843-1

Pierce-Williams R. A. M., Burd J, Felder L, et al. (2020). Clinical course of severe and critical coronavirus disease 2019 in hospitalized pregnancies: a United States cohort study. Am J Obstet Gynecol MFM, 2(3):100134. 10.1016/j.ajogmf.2020.100134

Pereira A., Cruz-Melguizo S., Adrien M., Fuentes L., Marin E., & Perez-Medina T. (2020). Clinical course of coronavirus disease-2019 in pregnancy. Acta Obstet Gynecol Scand. 99(7):839-847. 10.1111/aogs.13921

Qiao J. (2020). What are the risks of COVID-19 infection in pregnant women? Lancet, 395(10226):760-762. 10.1016/S0140-6736(20)30365-2

Rasmussen S. A., Smulian J. C., Lednicky J. A., Wen T. S., & Jamieson D. J., (2020). Coronavirus Disease 2019 (COVID-19) and pregnancy: what obstetricians need to know. Am J Obstet Gynecol. 222(5):415-426. 10.1016/j.ajog.2020.02.017

Remaeus K., et al. (2020). Characteristics and short-term obstetric outcomes in a case series of 67 women test-positive for SARS-CoV-2 in Stockholm, Sweden. Acta Obstet Gynecol Scand, 99(12):1626-1631. 10.1111/aogs.14006

Souza, M. T. de, Silva, M. D. da, & Carvalho, R. de. (2010). Revisão integrativa: o que é e como fazer. einstein, 8(1 Pt 1), 102-6. Disponível em: http://www.scielo.br/pdf/eins/v8n1/pt_1679-4508-eins-8-1-0102.pdf

Sahin D., et al. (2021). Updated experience of a tertiary pandemic center on 533 pregnant women with COVID-19 infection: A prospective cohort study from Turkey. Int J Gynaecol Obstet., 152(3):328-334. 10.1002/ijgo.13460

Schwartz D. A., (2020). An Analysis of 38 Pregnant Women With COVID-19, Their Newborn Infants, and Maternal-Fetal Transmission of SARS-CoV-2: Maternal Coronavirus Infections and Pregnancy Outcomes. Arch Pathol Lab Med., 144(7):799-805. 10.5858/arpa.2020-0901-AS

Savasi V. M., et al. (2020). Clinical Findings and Disease Severity in Hospitalized Pregnant Women With Coronavirus Disease 2019 (COVID-19). Obstet Gynecol. 136(2):252-258. 10.1097/AOG.0000000000003979

Sentilhes L., et al. (2020). Coronavirus disease 2019 in pregnancy was associated with maternal morbidity and preterm birth. Am J Obstet Gynecol. 223(6):914.e1-914.e15. 10.1016/j.ajog.2020.06.022

Sattari M., et al. (2020). Evaluating Clinical Course and Risk Factors of Infection and Demographic Characteristics of Pregnant Women with COVID-19 in Hamadan Province, West of Iran. J Res Health Sci. 20(3):e00488. 10.34172/jrhs.2020.22

Wang Y., et al. (2020). Impact of Covid-19 in pregnancy on mother's psychological status and infant's neurobehavioral development: a longitudinal cohort study in China. BMC Med. 18(1):347. 10.1186/s12916-020-01825-1

World Association of Perinatal Medicine (2021). Working Group on COVID-19. Maternal and perinatal outcomes of pregnant women with SARS-CoV-2 infection. Ultrasound Obstet Gynecol. 57(2):232-241. 10.1002/uog.23107

Wastnedge E. A. N., et al. (2021). Pregnancy and COVID-19. Physiol Rev. 101(1):303-318. 10.1152/physrev.00024.2020

Yan J., et al. (2020). Coronavirus disease 2019 in pregnant women: a report based on 116 cases. Am J Obstet Gynecol. 223(1):111.e1-111.e14. 10.1016/j.ajog.2020.04.014

Zaigham M., & Andersson, Ó. (2020). Resultados maternos e perinatais com COVID-19: Uma revisão sistemática de 108 gestações. Acta Obstet Gynecol Scand., 99: 823 - 829. https://doi.org/10.1111/aogs.13867

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16/09/2021

How to Cite

SANTOS, J. S. .; FERNANDES, M. I. da C. D. .; CAMACHO, E. N. P. R. .; BARBOSA, L. C. F. da S. .; FARIAS, P. de M. .; LIMA, T. N. B. de .; BARROSO, T. K. P. .; FREITAS, E. M. S. .; OLIVEIRA, C. de S. .; BEZERRA, A. G. C. .; SILVA , U. C. da .; LEAL, T. A. .; SILVA, A. de A. .; MOIA, A. de F. .; SANTO, M. S. do E. .; PEREIRA , G. M. .; SILVA, L. M. da .; ALVES, B. A. V. F. .; CARDOSO, A. M. de M. . Maternal clinical findings of sars-cov-2 infection in pregnancy: an integrative review. Research, Society and Development, [S. l.], v. 10, n. 12, p. e145101220188, 2021. DOI: 10.33448/rsd-v10i12.20188. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/20188. Acesso em: 5 nov. 2024.

Issue

Vol. 10 No. 12

Section

Review Article

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Copyright (c) 2021 Joelma Sena Santos; Maria Isabel da Conceição Dias Fernandes; Elyade Nelly Pires Rocha Camacho; Luciana Conceição Ferreira da Silva Barbosa; Patricia de Melo Farias; Tereza Natália Berra de Lima; Tereza Kariny Pontes Barroso; Elizangela Maria Silva Freitas; Clerislene de Sousa Oliveira; Ana Gabriela Carvalho Bezerra; Ulisses Clemente da Silva ; Tatiana Arimatéa Leal; Adenilde de Aparecida Silva; Adriana de Freitas Moia; Maiara Santos do Espirito Santo; Giovanna Medeiros Pereira ; Lilian Madorra da Silva; Bianca Alejandra Valdivia Frazão Alves; Alessandra Maria de Melo Cardoso

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