Comparative study between Valeriana Officinalis L. and diazepam: a literature review

Authors

DOI:

https://doi.org/10.33448/rsd-v10i13.21216

Keywords:

Diazepam; Valeriana officinalis; Conscious sedation; Benzodiazepines; Dentistry.

Abstract

The purpose of this study was to carry out a bibliographic review to compare the efficacy of Valeriana officinalis L. and the benzodiazepine diazepam, in order to control anxiety during the dental treatments, analyzing existing studies in the literature. It was carried out through a literature search using the electronic databases PUBMED, SCIELO, LILACS, COCHRANE BRASIL and EBSCOhost. The descriptors used for selection, both in English and in Portuguese, were conscious sedation, diazepam, Valeriana officinalis L., anxiolytics, benzodiazepines and Dentistry. As a Boolean operator, “and” was used. The articles reached through these search strategies were evaluated and defined as compatible or not, according to their relevance, type of drug application, giving priority to oral use, and also the clarity of ideas in the articles. It was concluded that the use of herbal medicines, such as Vallerina officinalis, by dentists is still little known and explored. Probably for this reason, there is a greater use of benzodiazepines, such as diazepam, as its mechanism of action is well known, as well as its indications and contraindications. Thus, clinical, controlled and double-blind studies are important to give more support to the indications and effectiveness of herbal medicines in relation to dental procedures.

References

Abdeshahi, S. K., Hashemipour, M. A., Mesgarzadeh, V., Payam, A. S., & Monfared, A. H. (2013). Effect of hypnosis on induction of local anaesthesia, pain perception, control of haemorrhage and anxiety during extraction of third molars: a case–control study. Journal of Cranio-Maxillofacial Surgery, 41(4), 310-315.

Andrade, E. D. (2014). Terapêutica medicamentosa em odontologia. Artes Médicas Editora.

Andreatini, R., Sartori, V. A., Seabra, M. L., & Leite, J. R. (2002). Effect of valepotriates (valerian extract) in generalized anxiety disorder: a randomized placebo‐controlled pilot study. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 16(7), 650-654.

Aeschliman, S. D., Blue, M. S., Williams, K. B., Cobb, C. M., & MacNeill, S. R. (2003). A preliminary study on oxygen saturation levels of patients during periodontal surgery with and without oral conscious sedation using diazepam. Journal of periodontology, 74(7), 1056-1059.

American Dental Association. (2016). Guidelines for the use of sedation and general anesthesia by dentists. Adopted by the ADA House of Delegates.

Barros, Elvino. Medicamentos de A a Z: 2016/2018. 5 ed. Porto Alegre: Artmed, 2016. 896 p.

Bissoli, J. R. (2013). Aspectos químicos e farmacológicos do medicamento fitoterápico Valeriana officinalis L.

Benzoni, T., & Cascella, M. (2019). Procedural sedation.

Brand, H. S., & Abraham‐Inpijn, L. (1996). Cardiovascular responses induced by dental treatment. European journal of oral sciences, 104(3), 245-252.

Chadwick, B. L. Assessing the anxious patient. Dent Update, v. 29, n. 9, p.448-454, 2002.

Cogo, K., Bergamaschi, C. D. C., Yatsuda, R., Volpato, M. C., & Andrade, E. D. D. (2006). Sedação consciente com benzodiazepínicos em odontologia. Revista de Odontologia da Universidade Cidade de São Paulo, 18(2), 181-8.

Corah, N. L., O'Shea, R. M., & Ayer, W. A. (1985). Dentists' management of patients' fear and anxiety. Journal of the American Dental Association (1939), 110(5), 734-736.

de Moares, M. B., Barbier, W. S., Raldi, F. V., Nascimento, R. D., Dos Santos, L. M., & Sato, F. R. L. (2019). Comparison of three anxiety management protocols for extraction of third molars with the use of midazolam, diazepam, and nitrous oxide: a randomized clinical trial. Journal of Oral and Maxillofacial Surgery, 77(11), 2258-e1.

de Morais, H. H. A., Barbalho, J. C. M., de Holanda Vasconcellos, R. J., Landim, F. S., da Costa Araújo, F. A., & de Souza Dias, T. G. (2015). Comparative study of hemodynamic changes caused by diazepam and midazolam during third molar surgery: a randomized controlled trial. Oral and maxillofacial surgery, 19(3), 267-273.

Dhaliwal, J. S., Rosani, A., & Saadabadi, A. (2020). Diazepam. StatPearls [Internet].

Faraco, F. N., Armonia, P. L., Simone, J. L., & Tortamano, N. (2003). Assessment of cardiovascular parameters during dental procedures under the effect of benzodiazepines: A double blind study. Brazilian dental journal, 14, 215-219.

Farah, G. J., Ferreira, G. Z., Danieletto-Zanna, C. F., Luppi, C. R., & Jacomacci, W. P. (2019). Assessment of Valeriana officinalis l.(Valerian) for conscious sedation of patients during the extraction of impacted mandibular third molars: a randomized, split-mouth, double-blind, crossover study. Journal of Oral and Maxillofacial Surgery, 77(9), 1796-e1.

Folayan, M., Ufomata, D., Adekoya-Sofowora, C., Otuyemi, O., & Idehen, E. (2003). The effect of psychological management on dental anxiety in children. Journal of Clinical Pediatric Dentistry, 27(4), 365-370.

Gonçalves, S., & Martins, A. P. (2006). Valeriana officinalis.

Hakeberg, M., Hägglin, C., Berggren, U., & Carlsson, S. G. (2001). Structural relationships of dental anxiety, mood, and general anxiety. Acta odontologica scandinavica, 59(2), 99-103.

Jerez Masaquiza, N. P. (2018). Uso de plantas medicinales como tranquilizante en la parroquia Salasaca (Bachelor's thesis, Universidad Técnica de Ambato-Facultad de Ciencias de la Salud-Carrera de Enfermería).

Kuang, H., Johnson, J. A., Mulqueen, J. M., & Bloch, M. H. (2017). The efficacy of benzodiazepines as acute anxiolytics in children: A meta‐analysis. Depression and anxiety, 34(10), 888-896.

Kulka, P. J., & Lauven, P. M. (1992). Benzodiazepine antagonists. Drug safety, 7(5), 381-386.

Lader, M. (2008). Effectiveness of benzodiazepines: do they work or not?. Expert Review of Neurotherapeutics, 8(8), 1189-1191.

Litchfield, N. B. (1980). Complications of intravenous diazepam—adverse psychological reactions.(An assessment of 16,000 cases). Anesthesia progress, 27(6), 175.

Melini, M., Forni, A., Cavallin, F., Parotto, M., & Zanette, G. (2020). Conscious sedation for the management of dental anxiety in third molar extraction surgery: a systematic review. BMC Oral Health, 20, 1-10.

Morethson, P., & Junior, O. C. (2015). Farmacologia para a clínica odontológica. Grupo Gen-Livraria Santos EDa.

Moura, I. M., Rocha, V. H. C., Bergamini, G. B., Samuelsson, E., Joner, C., Schneider, L. F., & Menz, P. R. (2018). A terapia cognitivo-comportamental no tratamento do transtorno de ansiedade generalizada. Revista Científica Da Faculdade De Educação E Meio Ambiente, 9(1), 423-441.

Pereira, L. H. M. D. C., Ramos, D. L. D. P., & Crosato, E. (1995). Ansiedade e dor em odontologia: enfoque psicofisiopatológico. Rev. Assoc. Paul. Cir. Dent, 285-90.

Pinheiro, M. L. P. (2003). Avaliação dos efeitos da Valeriana officinalis L no controle da ansiedade em pacientes submetidos a exodontias de terceiros molares mandibulares inclusos.

Rother, E. T. (2007). Revisión sistemática X Revisión narrativa

Santos, T. P. D. (2019). Análise de bulas e rótulos de medicamentos fitoterápicos à base de guaco.

Scott, D. S., & Hirschman, R. (1982). Psychological aspects of dental anxiety in adults. The journal of the American dental association, 104(1), 27-31.

Simões, C. M. O., Schenkel, E. P., de Mello, J. C. P., Mentz, L. A., & Petrovick, P. R. (2016). Farmacognosia: do produto natural ao medicamento. Artmed Editora.

Sivaramakrishnan, G., & Sridharan, K. (2017). Nitrous oxide and midazolam sedation: a systematic review and meta-analysis. Anesthesia progress, 64(2), 59-65.

Vassend, O. (1993). Anxiety, pain and discomfort associated with dental treatment. Behaviour research and therapy, 31(7), 659-666.

Wick, J. (2013). The history of benzodiazepines. The Consultant Pharmacist®, 28(9), 538-548.

Wu, J., Huo, J., Yu, D., Leng, D., & Du, X. (2019). Dynamic changes of the main active constituents in valerian rhizome and root (Valeriana amurensis Smir. ex Kom.) during different harvest periods. Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas, 18(5).

Yagiela, J. et al (2000). Farmacologia e Terapêutica Para Dentistas.

Published

10/10/2021

How to Cite

CAMPOS, G. S. .; PEREIRA, P. C. de O. A. .; ANDRADE, R. S. de . Comparative study between Valeriana Officinalis L. and diazepam: a literature review. Research, Society and Development, [S. l.], v. 10, n. 13, p. e231101321216, 2021. DOI: 10.33448/rsd-v10i13.21216. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/21216. Acesso em: 8 dec. 2021.

Issue

Section

Review Article