Clinical gastrointestinal manifestations in patients with COVID-19




COVID-19; Signs and Symptoms, Digestive; Gastrointestinal tract.


Objective: To identify the clinical manifestations of the gastrointestinal tract in patients affected by COVID-19 and monitored by the Municipal Health Department of Aracaju. Methodology: retrospective, cross-sectional, survey-type study, carried out from March to July 2020, based on information contained in a database of the Health Department of Aracaju. Sample composed of 3,342 patients registered in the telemonitoring program of the Department, who were tested and confirmed by RT-PCR for SARS-CoV-2. Data analyzed using percentage frequency, Pearson, Shapiro-Wilks and Mann-Whitney tests. Adopted significance level of 5%. Results and Discussion: 938 (27.36%) patients with gastrointestinal manifestations were registered: diarrhea 637 (18.58%), abdominal pain 158 (4.61%), nausea 156 (4.55%), vomiting 89 (2 .6%) and anorexia 119 (3.47%). With a mean age of 39.1 (±14.8) years, 563 (60%) were female and 930 (99.9%) lived in Aracaju or nearby. The mean age of severe cases was 55.5 (±18.9) years and 53.9% were male. The average duration of gastrointestinal symptoms was 6.5 days. All severe cases were hospitalized and, of these, 4 (0.5%) died. Main comorbidities associated with severe cases (p<0.05): cardiovascular diseases, diabetes mellitus, chronic kidney disease, cancer and neurological diseases. Conclusion: there was an important association between gastrointestinal symptoms in patients with COVID-19, especially in young and female patients. The presence of previous comorbidities was a statistically significant factor for the appearance of digestive tract manifestations.


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How to Cite

SILVA, L. F. A. da; CARDOSO, D. S.; SOUSA, L. F. de O.; DOURADO, M. R. M.; JESUS, P. H. S. de; LIMA, E. O.; BRITTO NETO, H. S.; MEDINA, M. S. L.; SILVEIRA, L. T.; ROCHA, C. G. S.; ANDRADE, A. R. O. de; TRINDADE, L. M. D. F. Clinical gastrointestinal manifestations in patients with COVID-19. Research, Society and Development, [S. l.], v. 10, n. 13, p. e423101321542, 2021. DOI: 10.33448/rsd-v10i13.21542. Disponível em: Acesso em: 7 dec. 2021.



Health Sciences