Association between Sequential Organ Failure Assessment scores and mortality in mechanically ventilated patients admitted to an Intensive Care Unit
DOI:
https://doi.org/10.33448/rsd-v10i14.22176Keywords:
Sepsis; Organ dysfunction scores; SOFA scale; Intensive care units.Abstract
Sepsis is a syndrome defined as a systemic and disordered response to a specific infectious condition, caused by any microorganism, presenting itself in different clinical stages of the same pathophysiological process. Early identification of sepsis is essential, in addition to the use of scales to quickly identify the affected organs in order to optimize the administration of certain hospital resources. The aim of this study is to investigate the association between Sequential Organ Failure Assessment (SOFA) scale scores and mortality of patients admitted to an intensive care unit. This is a prospective cohort study with document analysis. The respiratory and coagulation systems were not associated with mortality. However, the scores of the other 4 systems (hepatic, cardiovascular, neurological and renal) showed a strong association with mortality in the study sample (p-value <0.05). It was possible to show that the SOFA scale is a predictor of mortality associated with organ dysfunction in patients with infection, hospitalized in a intensive care unit.
References
Borges, A. C. do N., Costa, A. L., Bezerra, J. B., Araújo, D. S., Soares, M. A. A., Gonçalves, J. N. de A., Rodrigues, D. T. da S., Oliveira, E. H. S. De, Luz, L. E. Da, Silva, T. R., & Silva, L. G. de S. (2020). Epidemiology and pathophysiology of sepsis: an review. Research, Society and Development, 9(2), e187922112.https://doi.org/10.33448/rsd-v9i2.2112
Brasil. Agência Nacional de Vigilância Sanitária (2010). Dispõe sobre os requisitos mínimos para funcionamento de Unidades de Terapia Intensiva e dá outras providências. https://bvsms.saude.gov.br/bvs/saudelegis/anvisa/2010/res0007_24_02_2010.html
Carvalho, P. P., Porto, M. de J., Barros, J. F., Magalhães, A. S., Nunes, L. S., Silva, I. C., Abreu, I. L. S. de, Souza, G. N., Rezende Neto, J. M. de., & Mendes, T. da S. (2021). Evaluation of critical patients with suspected sepsis in a university hospital. Research, Society and Development, 10(3), e39410313570. https://doi.org/10.33448/rsd-v10i3.13570
Chowdhury, D., & Duggal A. K. (2017). Intensive care unit models: Do you want them to be open or closed? A criticalreview. NeurolIndia, 65(1), 39-45. 10.4103/0028-3886.198205. PMID: 28084236.
de Freitas, G. R. C., Da Fonseca-Neto, O. C. L., Pinheiro, C. L. F., Araújo, L. C., Barbosa, R. E. N., & Alves, P. (2014). Relação entre o Sequential Organ Failure Assessment (SOFA) e a pressão intra-abdominal em unidade de tratamento intensivo. Arq Bras Cir Digl. 27(4). http://www.scielo.br/scielo.php?pid=S010267202014000400256&script=sci_arttext&tlng=pt
Dyusembekov, E., Akhanov, G., Aliev, M., Uteuliyev, Y., & Saktapov, A. (2018). Georgian medical news, (285), 17–20.
Hulley, S. B., Cummings, S. R., Browner, W. S., & Grady, D. G. (2014). Delineando a pesquisa, Porto Alegre, Artmed.
Instituto Americano de Sepse. (2015). Sepse: um problema de saúde pública. Brasília: CFM.
Júnior, L. C. M. C., & Da Silva, R. R. (2014). Sepse em pacientes internados em unidade de terapia intensiva com lesão cerebral traumática: fatores associados a maior mortalidade. Rev Bras Ter Intensiva, 26 (2): 148-154. http://www.rbti.org.br/artigo/detalhes/0103507X-26-2-11
Pinto, C. da S. P., Santos, M. V. dos., & Simor, A. (2021). Control factors and progression of sepsis in the Intensive Care Unit: a literature review. Research, Society and Development, 10(14), e38101421750. https://doi.org/10.33448/rsd-v10i14.21750
Raith, E. P., Udy, A. A., Bailey, M., McGloughlin, S., MacIsaac, C., Bellomo, R., Pilcher, D. V., & Australian and New Zealand Intensive Care Society (ANZICS) Centre for Outcomes and Resource Evaluation (CORE) (2017). Prognostic Accuracy of the SOFA Score, SIRS Criteria, and qSOFA Score for In-Hospital Mortality Among Adults With Suspected Infection Admitted to the Intensive Care Unit. JAMA, 317(3), 290–300. https://doi.org/10.1001/jama.2016.20328
Seymour, C. W., Liu, V. X., Iwashyna, T. J., Brunkhorst, F. M., Rea, T. D., & Scherag, A. (2016). Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). Rev JAMA. 315(8): 762-74. https://jamanetwork.com/journals/jama/fullarticle/2492875
Silva, L. E. C., Lima, M. B. e S., Silva & Államy, D. M. E. (2020). Nurse’s performance in the prevention and identification of sepsis signs and symptoms in intensive therapy: an integrative review. Research, Society and Development, 9(11), e1229119599. https://doi.org/10.33448/rsd-v9i11.9599
van Vught, L. A., Klouwenberg, P. M. K., Spitoni, C., Scicluna, B. P., Wiewel, M. A., Horn, J., Schultz, M. J., Nürnberg, P., Bonten, M. J., Cremer, O. L., & van der Poll, T. (2016), MARS Consortium. Incidence, Risk Factors, and Attributable Mortality of Secondary Infections in the Intensive Care Unit After Admission for Sepsis. JAMA. 12;315(14):1469-79. 10.1001/jama.2016.2691. PMID: 26975785
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2021 Silvio Cesar da Conceição; Luana Dias Lisboa; Thainá Araújo de Campos; Andréa da Silva Gomes Ludovico; Ádane Viana; Marcelo Dehoul
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
