Diagnosis of high-degree myofibrosarcoma in dog – case report

Authors

DOI:

https://doi.org/10.33448/rsd-v10i15.22249

Keywords:

Neoplasm; Sarcoma; Immunohistochemistry; Dog.

Abstract

Soft tissue sarcomas (STM) in veterinary oncology comprise a group of malignant mesenchymal neoplasms, mainly affecting the skin and subcutaneous tissue, with ill-defined margins with high rates of local recurrence and moderate metastatic potential. Routine diagnosis is based on the animal's history, clinical signs, but confirmation is performed through cytological and histopathological exams. In addition to chemotherapy, radiotherapy and surgical removal are used to provide greater survival for patients. The present study aims to report a case of High-Grade Myxofibrosarcoma, detected by immunohistochemical examination, a variation of (STM), in a one-year-old male patient, Brazilian row, treated at a clinic veterinarian located in the city of Vilhena- Rondônia, initially presenting a nodule in the region of the right scapula, with rapid evolution and progressive growth after surgical removal. The guardians opted for the animal's euthanasia.

References

Robert, K. Y. & Daniel, G. (2001) Estudo de caso: planejamento e métodos. 2.ed. https://saudeglobaldotorg1.files.wordpress.com/2014/02/yin-metodologia_da_pesquisa_estudo_de_caso_yin.pdf.

Bellei, M. H. M., Neves, D. S., & Gava, A. (2006) Prevalence study of canine skin tumours in Santa Catarina, Brazil, between 1998 and 2002., 73-79.

Tian, Z., Wang, J., & Yang, J. (2021) et al. Apatinib with doxorubicin and ifosfamide as neoadjuvant therapy for high-risk soft tissue sarcomas: a retrospective cohort study. Invest New Drugs 39, 1724–1731. https://doi.org/10.1007/s10637-021-01139-w

Bronden, L. B., Eriksen, T., & Kristensen, A. T. (2010) Mast cell tumours and other skin neoplasia in Danish dogs.

Carlton, W. W., & Mc Gavin, M. D. (1998) Patologia veterinária especial de Thomsom. 742-743.

Greto D, Loi M, & Saieva C, (2018) et al. Safety of concurrent adjuvant radiotherapy and chemotherapy for locally advanced soft tissue sarcoma. Tumori Journal. 104(5):322-329. 10.1177/0300891618765565

Dudgeon, L. S., & Patrick, C. V. (1927) A new method for the rapid microscopical diagnosis of tumors: with na account of 200 cases so examined. The British Journal of Surgery, p. 250-261.

Eich, C. S., Whitehair, J. G., Moroff, S. D., & Heeb, L. A (2000) The accuracy of intraoperative cytopathological dianosis compared with conventional histopathological diagnosis. Journal of the American Animal Hospital Association, 36(1), 16-8.

El-jabbbour, J. N., Akhtar, S.S., Kerr, G. R., Mclaren, K. M., Smyth, A. & Rodger F. C. Leonard. Prognostic Factors for Survival in Soft Tissue Sarcoma. Br. J. Cancer, 62, 857-61. 1990.

Enzinger, F.M., Lattes, R., & Torloni, R. (1969) Histological typing of soft tissue tumors Internacional Histological Classification of Tumors. World Health Organization.

Gardner, D. G., & Baker, D. C. (2013) Canine oral fibrosarcomas: a retrospective analysis of 65 cases (1998-2010). Veterinary and comparative oncology, 1-8.

Ginn, P. E., Mansell, J. E. K. L., Rakich, P. M. Jubb, K. V. F., Kennedy, P. C., & Palmer’s, N. C. (2007) Pathology of domestic animals. 5 ed. Philadelphia: Saunders Elsevier. 1, Cap. 5, 553-781.

Goldschmidt, M. H., & Hendrick, M. J. (2002) Tumors in domestic animals. (4a ed.) Ames: Iowa State, 2, 44-117.

Gross T. L., Ihrke P. J., Walder E. J., & Affolter V. K. (2005) Skin Disease of the Dog and Cat, Clinical Histopathologic Diagnosis. (2nd Ed) Oxford. Blackwell Publishing, 616-626.

Jones, T.C., Hunt, R. D., & King, N.W. (2000) Patologia veterinária. (4a ed.) Manole, 1053-1059.

Kaldrymidou, H., Leontides, L., & Koutinas, A. F (2002). et al. Prevalence, distribution and factors associated with the presence and the potential for malignancy of cutaneous neoplasms in 174 dogs admitted to a clinic in northern Greece. J. Vet. Med. A. Physiol. Pathol. Clin. Med., 49(2), 87-91.

Kindblom, L.G., Lodding, P., & Angervall, L. (1983) Clear cell sarcoma of tendons and aponeuroses. Virchows Arch. A, 401, 109-128.

Machado, A. V., Silva, J. M. L., & Curial, O. (1963) Incidência de blastomas em animais no Brasil. Arq. Esc. Vet., 25, 327-401.

Mcentee, M. C. (2012) Veterinary radiation therapy: review and current state of the the art. Oral and maxillofacial surgery in dogs and cats. Pennsylvania: Elsevier. 387-402.

Meirelles, A. E. W. B., Oliveira, E. C., & Rodrigues, B. A. (2010) et al. Prevalência de neoplasmas cutâneos em cães da Região Metropolitana de Porto Alegre, RS: 1.017 casos (2002-2007). Pesq. Vet. Bras., 30(11), 968-973.

Moulton, J. E. Tumors in domestic animals. (1990) 3. ed. California: university of California press, 25-27.

Parkin D. M. (1992) Cancer incidence in five Continents. Iarc Scientific Publications, 120, 456.

Pakhrin, B., Kang, M. S., Bae, I. H. et al. (2007) Retrospective study of canine cutaneous tumors in Korea. J. Vet., 8(3), 229-236.

Ramos-vara, J. A., Kiupel, M., & Baszler, T. (2008) et al. Suggested guidelines for immunohistochemical techniques in veterinary diagnostic laboratories. J. Vet. Diagn. Invest., 20(4), 393-413.

Rothman, K. (1986) Epidemiology.J.Modern Epidemiology.Brow and Company, 123, 478.

Ruiz, F. S., Alessi, A. C., & Chagas, C. A. (2005) et al. Imuno-histoquímica na patologia veterinária diagnóstica: uma revisão crítica. J. Bras. Patol. Med. Lab., 41(4), 263-270.

Santos, J. A. (1988) Patologia geral dos animais domésticos. (3a ed.) Guanabara, 314-315.

Scott, D. W., Miller, W. H., & Griffin, C. E. (2001) Muller & Kirk. Small animal dermatology. (6a ed.) Saunders Company.

Souza, T. M., Fighera, R. A., & Irigoyen, L. F. (2006) et al. Estudo retrospectivo de 761 tumores cutâneos em cães. Cienc. Rural., 36(2), 555-560.

Teixeira, T. F., da Silva, T. C., & Cogliati, B. (2010) et al. Retrospective study of melanocytic neoplasms in dogs and cats. Braz. J. Vet. Pathol., 3(2), 100-104.

Vail D. M., & Withrow S. J. Tumors of the Skin and Subcutaneous Tissues. (2001). Small Animal Clinical Oncology. (3a ed.) W. B. Saunders, 233-260.

Withrow, S. J, & Macewen’s, E. G. (2007) Small clinical veterinary oncology. Why worry about cancer in pets. (5a ed.) Saunders Elsevier.

Yager, J. A., & Wilcock, B. P. (1994) Color atlas and text of surgical pathology of the dog and cat. London: Wolfe, 1, 291-292.

Yager, J. A., & Wilcock, B. P. (1994) Tumors of the skin and associated tissues Color atlas and text of surgical pathology of the dog and cat dermatopathology and skin tumors. Wolfe. 1, 239-31.

Published

17/11/2021

How to Cite

KAVASAKI, M. L. .; BARBOZA, M. T. .; STEIN, J. A. .; RIEGER, G. .; ROCHA, L. da S. .; TROGUILHO, A. de O. . Diagnosis of high-degree myofibrosarcoma in dog – case report . Research, Society and Development, [S. l.], v. 10, n. 15, p. e36101522249, 2021. DOI: 10.33448/rsd-v10i15.22249. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/22249. Acesso em: 25 apr. 2024.

Issue

Section

Agrarian and Biological Sciences