Primary orbital melanomas: a narrative review of the literature

Authors

DOI:

https://doi.org/10.33448/rsd-v10i17.23682

Keywords:

Ocular neoplasms; Carcinoma; Conjunctival neoplasms.

Abstract

Choroidal melanoma is the most common cancer to affect the eye in adults - it is also called ocular melanoma or uveal melanoma. The annual incidence of ocular melanoma is approximately 10 cases for every million inhabitants, which means that for every million people we have 10 cases a year. In Brazil we have approximately 2,000 cases of this disease per year. To meet the objectives of the work, an integrative quantitative and qualitative literature review was carried out, in which the following steps were followed: definition of the theme and elaboration of the research question; elaboration of the eligibility, inclusion and exclusion criteria of the studies; definition of descriptors, literature search and data collection; critical analysis of included studies and discussion of results; and presentation of the review summary. Due to the high mortality that the disease presents, associated with the great importance that the visual function and visual aesthetics have in the integration of the individual with the social environment, the importance of early diagnosis and treatment of the disease is highlighted.

References

Barsotti, V., Aguiar, G. M. F., Abatti, R. E. M., Boldrini, L., Kumagai, K. M., & Freitas, J. A. H. Carcinoma espinocelular de conjuntiva. Rev Fac Cienc Med Sorocaba. 9:23-6.

Cerbone, L., Van Ginderdeuren, R., Van Den Oord, J., Fieuws, S., Spileers, W., Van Eenoo, L., Wozniak, A., Sternberg, O. N., & Schoffski, P. Clinical presentation, pathological features and natural course of metastatic uveal melanoma, an orphan and commonly fatal disease. Oncology. 2014;86(3):185-189. http://dx.doi.org/10.1159/000358729.

Crawford, J. B. (1995) Conjunctival Tumors. IN: Tasman W, & Jaeger E. A. Duane's clinical ophthalmology. Philadelphia: Lippincott. 4, 1-10.

Dutton, J. J., Fowle, R. A. M., & Proia, A. D. (2006) Dermoid cyst of conjunctival origin. Ophthal Plast Reconstr Surg., 22:137-9. https://doi.org/10.1097/01.iop.0000199251.29558.0b

Fernandes, B. F., Belfort, R. N., DI Cesare, S., & Burnier JR, M. N (2008). Circulating uveal melanoma cells: should we test for them? Can J Ophthalmol. 43(2):155-158. http://dx.doi.org/10.3129/i08-011.

Font, R. L., Del Valle, M., Aveda-O, J., Longo, M., & Boniuk, M. (2008) Primary adenoid cystic carcinoma of the conjunctiva arising from the accessory lacrimal glands: a clinicopathologic study of three cases. Cornea. 27:494-7. https://doi.org/10.1097/ICO.0b013e318162a907.

Giblin, M. E., Shields, J. A., AugsburgeR, J. J., & Brady, L. W. (1989) Episcleral plaque radiotherapy for uveal melanoma. Aust N Z J Ophthalmol. 17(2):153-156. http://dx.doi.org/10.1111/j.1442-9071.1989.tb00505.x.

Hospital Das Clínicas (São Paulo), Organizador. Clínica Oftalmológica. Anatomia e fisiologia do olho: anatomia e fisiologia [Internet]. Cap. 1 https://www.passeidireto.com/arquivo/17566215/oftalmologia ---apostila-usp.

Junqueira, L. C., & Carneiro, J. Histologia básica: texto e atlas. (10a ed.), Guanabara Koogan.

MAshayekhi, A., Shields, C. L., Rishi, P., Atalay, H. T., Pellegrini, M., Mclaughlin, J. P., et al. (2014) Primary transpupillary thermotherapy for choroidal melanoma in 391 cases: importance of risk factors in tumor control. Ophthalmology. Forthcoming. http://dx.doi.org/10.1016/j-ophtha.2014.09.029.

Onken, M. D., WOrley, L. A., Char, D. H., Augsburger, J. J., Correa, Z. M., Nudleman, E., et al. (2012) Collaborative Ocular Oncology Group report number 1: prospective validation of a multi-gene prognostic assay in uveal melanoma. Ophthalmology. 119(8):1596-1603. http://dx.doi.org/10.1016/j-ophtha.2012.02.017.

Pereira, A. P. F. Lesões não melanocíticas da conjuntiva: benigna, pré-malígna e maligna [dissertação]. Coimbra: Faculdade de Medicina. Universidade de Coimbra.

Saornil, M. A., Becerra, E., & Méndez, M. C., Blanco, G. (2009) Tumores de la conjuntiva. Arch Soc Esp Oftalmol. 84:7-22. https://doi.org/10.4321/S0365-66912009000100003

Shields, J. A., & Shields, C. L. (2015) Management of posterior uveal melanoma: past, present, and future: the 2014 Charles L. Schepens lecture. Ophthalmology. 122(2):414-428. http://dx.doi.org/10.1016/j.ophtha.2014.08.046.

Yanoff, M., & Duker, J. S. (2011) Oftalmologia. In: Goldstein MH, editor. Córnea e doenças da superfície ocular. (3a ed.), Elsevier. p. 241.

Published

25/12/2021

How to Cite

CALABRIA, A. C. .; KEMPFER, A. V. .; OMIZZOLO, J. A. E. . Primary orbital melanomas: a narrative review of the literature. Research, Society and Development, [S. l.], v. 10, n. 17, p. e103101623682, 2021. DOI: 10.33448/rsd-v10i17.23682. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/23682. Acesso em: 21 may. 2022.

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