Benefits of kojic acid in the treatment of hyperchromis
DOI:
https://doi.org/10.33448/rsd-v10i16.23841Keywords:
Kojic Acid; Hyperpigmentation; Depigmenting.Abstract
Skin hyperchromias are common sequelae due to some disorder in the physiological process, including aging, hormonal changes, inflammation, allergies and excessive sun exposure. The tissue hyperpigmentation process occurs due to increased production of melanin by cells named melanocyte, tissue abnormality that affects many people and consequently their quality of life. Its objective is to describe through existing literature the benefits of kojic acid in the treatment of cutaneous hyperchromia. This study is an integrative literature review, using scientific articles and books that already exist on online platforms as a data source. Experimental and non-experimental researches were found that prove the effectiveness of the active kojic acid in its pure concentration or in combination with other lightening substances. Although there are few studies on the subject, it is concluded that the depigmenting active of kojic acid is a safe and efficient alternative in the treatment of spots, due to its natural and non-cytotoxic formulation.
References
Al- Edresi, S., & Baie, S. (2010). In-vitro and in-vivo evaluation of a photo-protective kojic dipalmitate loaded ento nano-creams. Asian Journal of Pharmaceutical Sciences. (5a ed).
Costa, A., Arruda, A. F., Pereira, L. H., Pereira, E. S., Santos, M., Calixto, F. B., & Favaro, R. (2012). Estudo clínico para a avaliação das propriedades clareadoras da associação de ácido kójico, arbutin, sepiwhite e achromaxyl na abordagem do melasma, comparada a hidroquinona 2% e 4%. Sociedade Brasileira de Dermatologia Brasil. 4(1).
Baumann, L. M. D. (2004). Dermatologia Cosmética Princípios e Práticas. Revinter. 3-4.
Borges, F. (2010). Dermato-funcional: Modalidades Terapêuticas nas Disfunções Estéticas. Phorte.
Bauer, M. W. Gaskell, G., & Allun, N. C. (2008). Qualidade, quantidade e interesses do conhecimento: Evitando confusões. Guareschi. (7a ed.).
Callender, V.D., St Surin-Lord S., Davis, E.C & Maclin, M. (2011). Postinflammatory hyperpig: mentation: etiologic and therapeutic considerations. Am J Clin Dermatol. 12(2):87-99.
Davis, E. C., & Callender, V. D. (2010). Postinflammatory hyperpigmentation: a review of the epidemiology, clinical features, and treatment options in skin of color. J Clin Aesthet Dermatol. 3(7):20-31.
Gonchoroski, D. D. & Corrêa, M. G. (2005). Tratamento da hipercromia pós-inflamatória com diferentes formulações clareadoras. Rev. Inframa. 17(3/4).
Gil, A. C. (2008). Como elaborar projetos de pesquisa. Atlas. (4a ed.) 41-42
Gomes, A. J. (2001). The antioxidant action of Polypodium leucotomos extract and kojic acid: reactions with oxygen species. Brazilian Journal of Medical and Biological Research, 34.
Kwak, S. Y., Noh, J. M., Park, S. H., Byun, J.-W., Choi, H. R., Park, K. C., & Lee, Y. S. (2010). Enhanced cell permeability of kojic acid-phenylalanine amide with metal complex. Bioorganic & Medicinal Chemistry Letters. 20, 738–741.
Lin Jy & Fisher D.E. (2007). Melanocyte biology and skin pigmentation. Nature.
Moura, M. C. (2017). O uso de ácidos e ativos clareadores associados ao microagulhamento no tratamento de manchas hipercrômicas: estudo de caso.
Mendes, A. L. L., & Fracolli, L. A. (2008). Revisão sistemática de literatura e metassíntese qualitativa: considerações sobre sua aplicação na pesquisa em enfermagem. Texto Contexto Enfermagem, 17(4), 771–779.
Mitani, H. (2001). Prevention of the photodamage in the hairless mouse dorsal skin by kojic acid as an iron chelator. European Journal of Pharmacology. 411(1), 169–174.
Nicoletti, M. A. (2002). Hipercromias: aspectos gerais e uso de Despigmentantes cutâneos. Cosmetics & Toiletries. (14a ed.).
Oliveira, K. A., & Vieira, R. M. (2020). Eficácia do ácido kójico em associação ao ácido salicílico no tratamento de hipercromias pós-inflamatórias em diferentes fototipos de pele. Revista eletrônica interdisciplinar, 12.
Pontes, C. G. (2012). Ácido Kójico no Tratamento do Melasma. Faculdade Cambury.
Pompeo, D. A., Rossi, L. A., & Galvão, C. M. (2009). Revisão integrativa: etapa inicial do processo de validação de diagnóstico de enfermagem. Acta paul.enferm, 22(4),6.
Rodrigues, A. P. D., Carvalho, A. S. C., Santos, A. S., Alves, C. N., Nascimento, J. L. M., & Silva, E. O. (2011). Kojic acid, a secondary metabolite from aspergillus. Acts as an inducer of macrophage activation. Cell Biology International. (35a ed.).
Souza, Carvalho, L., Amurim., Pereira, N., Grignoli, Cristina, L., & Esquissato, M. (2018). O uso associado do ácido kòjico e Ácido Glicólico como alternativa à hidroquinona no Tratamento de melasma. Revista científica multidisciplinar, 2.
Saeedi, M., Eslamifar, M., & Khezri, K. (2019). Kojic acid aplications in cosmetic and pharmaceutical preparativos. Biomed Pharmacother.
Silva, L. G., Simonis., Henrique, M., & Mariana. (2015). Associação do peeling de ácido kójico e ácido Glicólico no tratamento de Melasma: um estudo de caso. 2237 Tcc (graduação)- curso de Estética e Cosmética, Unisc, Santa Cruz do sul.
Solon, L. M. D., Cordeiro, A. E., Viana F. C. S., & Barbosa Martins, A. (2020). Efeitos dos ácido kójico e belides no clareamento de hipercromias da região axilar. Revista diálogos Acadêmicos, 9(1)
Souza, Menezes L., Dias Santos, G., Silva, R. A., & Meireles Batista, C. (2021). Desenvolvimento de desodorante roll on de ácido kójico como alternativa para clareamento de axilas. Interfaces Científicas, 8(3).
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2021 Cintia da Silva Oliveira; Giovanna Inácio de Andrade; Jeane Rocha Santo
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.