Feline hyperthroidism secondary to thyroid adenocarcinoma

Authors

DOI:

https://doi.org/10.33448/rsd-v10i16.24069

Keywords:

Endocrinopathy; Adenocarcinoma; Feline.

Abstract

Hyperthyroidism refers to the increase in functional thyroid hormones, thyroxine (T4) and triiodothyronine (T3). Most cases of hyperthyroidism are caused by thyroid adenoma or multinodular adenomatous hyperplasia, affecting one or both lobes of the thyroid gland. Less than 5% of cases occur as a result of thyroid carcinoma. Thus, this study aimed to present a case report about feline hyperthyroidism caused by thyroid carcinoma, in an 11-year-old male feline. The animal had a history of anorexia, vomiting and diarrhea about a month ago. Complete blood count, biochemical, abdominal ultrasound and CT scan of the cervical region were requested. Laboratory and physical examinations indicated strong signs of hyperthyroidism, such as erythrocytosis, increase in total T4 and increase in the palpable volume of the thyroid, in addition to tomographic examination indicative of neoplastic process in the left thyroid lobe, without involvement of adjacent structures. The treatment of choice was surgery with the modified extracapsular technique with a cervical approach (thyrodectomy with preservation of the parathyroid glands). After surgical procedures and supportive treatment, the animal presented remission of clinical signs.

References

Behrend, E. N. (2006). Update on drugs used to treat endocrine diseases in small animals. Veterinary Clinics: Small Animal Practice, 36(5), 1087-1105.

Birchard, S. J. (2006). Thyroidectomy in the cat. Clinical Techniques in Small Animal Practice, 21(1), 29-33.

Borges, D. S., Casarin, C. S., Borges, L. T., & Leite, A. T. M. (2010). Tireoidectomia extracapsular com transplante de paratireóide em felino-Relato de caso. MEDVEP. Revista Científica de Medicina Veterinária, 593-597.

Bush, J. L., Nemanic, S., Gordon, J., & Bobe, G. (2016). Computed tomographic characteristics of the thyroid glands in eight hyperthyroid cats pre- and post methimazole treatment compared with seven euthyroid cats. Veterinary Radiology & Ultrasound, 1–10.

Daleck, C. R., & De Nardi, A. B. (2016). Oncologia em cães e gatos . Grupo Gen-Editora Roca Ltda.

Daminet, S., Kooistra, H. S., Fracassi, F., Graham, P. A., Hibbert, A., Lloret, A., Mooney, C. T., Neiger, R., Rosenberg D., Villard, I. & Williams, G. (2014). Best practice for the pharmacological management of hyperthyroid cats with antithyroid drugs. Journal of Small Animal Practice, 55(1), 4-13.

Gunn-Moore, D. (2005). Feline endocrinopathies. Veterinary Clinics: Small Animal Practice, 35(1), 171-210.

Hibbert, A., Gruffydd-Jones, T., Barrett, E. L., Day, M. J., & Harvey, A. M. (2009). Feline thyroid carcinoma: diagnosis and response to high-dose radioactive iodine treatment. Journal of Feline Medicine and Surgery, 11, 116-124.

Lautenschlaeger, I. E., Hartmann, A., Sicken, J., Mohrs, S., Scholz, V. B., Neiger, R., & Kramer, M. (2013). Comparison between computed tomography and 99m TC- pertechnetate scintigraphy characteristics of the thyroid gland in cats with hyperthyroidism. Veterinary Radiology & Ultrasound, 54, 666–673.

Lavallee, J., Olson, J. K., & Norsworthy, G. D. (2018). HypertireodismIn The feline patient (5a ed). Wiley Blackwell.

Little, S. E. (2015). O gato: medicina interna; tradução Roxane Gomes dos Santos Jacobson, Idilia Vanzellotti.

Macphail, C., & Fossum, T. W. (2019). Surgery of the endocrine system. In: Fossum, T. W. (Org.), Small Animal Surgery (5a ed) (Cap. 22, pp. 586-630). USA: Mosby, inc.

Mooney, C. T. (2001). Feline hyperthyroidism. Veterinary Clinics of North America: Small Animal Practice, 31(5), 963-983.

Norsworthy, G. D., Adams, V. J., McElhaney, M. R., & Milios, J. A. (2002). Relationship between semi-quantitative thyroid palpation and total thyroxine concentration in cats with and without hyperthyroidism. Journal of feline medicine and surgery, 4(3), 139-143.

North, S., & Banks, T. (2009). Introduction to small animal oncology. Saunders. California, USA, 159-160.

Peterson, M. (2012). Hyperthyroidism in cats: what’s causing this epidemic of thyroid disease and can we prevent it?. Journal of feline medicine and surgery, 14(11), 804-818.

Peterson, M. E. (2006). Diagnostic tests for hyperthyroidism in cats. Clinical techniques in small animal practice, 21(1), 2-9.

Peterson, M. E. (2020). Hyperthyroidism in cats: considering the impact of treatment modality on quality of life for cats and their owners. Veterinary Clinics: Small Animal Practice, 50(5), 1065-1084.

Vail, D. M., Thamm, D. H., & Liptak, J. M. (2019). Hematopoietic tumors. Withrow and MacEwen's small animal clinical oncology, 688.

Van, Hoek, I., & Daminet, S. (2009). Interactions between thyroid and kidney function in pathological conditions of these organ systems: a review. General and comparative endocrinology, 160(3), 205-215.

Published

19/12/2021

How to Cite

SILVA, R. B. da .; TORRES, V. L. .; RIBEIRO, A. B. F. .; SOUSA FILHO, R. P. de .; ANASTÁCIO, F. D. L. .; FREITAS, L. J. dos S. .; LIMA, G. R. F. .; SIQUEIRA, L. C. .; TEIXEIRA, G. G. . Feline hyperthroidism secondary to thyroid adenocarcinoma. Research, Society and Development, [S. l.], v. 10, n. 16, p. e304101624069, 2021. DOI: 10.33448/rsd-v10i16.24069. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/24069. Acesso em: 13 nov. 2024.

Issue

Section

Agrarian and Biological Sciences