Covid-19: an analysis of reports of positive cases in the State of Paraná in 2020, with emphasis on chronic kidney disease

Authors

DOI:

https://doi.org/10.33448/rsd-v10i17.24154

Keywords:

SARS-CoV-2; Coronavirus infections; Chronic kidney disease.

Abstract

Covid-19 is an infectious disease caused by the SARS-CoV-2 coronavirus that has resulted in a global pandemic. Its main mechanism of entry into cells is through the angiotensin-2 converting enzyme (ACE-2) and the elderly and those with chronic non-communicable diseases (NCDs) are part of the risk group, including chronic kidney disease (CKD). The objective was to characterize the sample of individuals reported with Covid-19 and CKD, according to clinical and demographic characteristics. Quantitative, cross-sectional study, with retrospective data, obtained through a secondary database, from the e-SUS NOTIFICA system, from March 2020 to December 8, 2020. For the period analyzed, the total number of notifications was of 992,911 individuals, being 110,908 tested positive. A descriptive analysis was performed and only patients with a confirmed diagnosis of Covid-19 were included. Thus, it was concluded that, among the total of positive analyzed, the majority were male (46.2%), with a mean age of 41.42 years and of these, 445 had CKD. Still, of the 110,908 cases, 52.4% had some type of symptom characteristic of Covid-19. The most used test for diagnosis was the Rapid Test – Antibody (93.3%). For patients with CKD and Covid-19, there was a predominance of females (53.0%), the mean age was 53.71 years, the majority symptomatic (59.3%), with the diagnosis confirmed by the Rapid Test - Antibody (86.5%).

References

Abreu, A. P. de, Riella, M. C., & Nascimento, M. M. do. (2020). The Brazilian Society of Nephrology and the Covid-19 Pandemic. Brazilian Journal of Nephrology, 42(2 suppl 1), 1–3.

Almeida, J. dos S., Cardoso, J. A., Cordeiro, E. C., Lemos, M., Araújo, T. M. E. de, & Sardinha, A. H. de L. (2020). EPIDEMIOLOGICAL CHARACTERIZATION OF COVID-19 CASES IN MARANHÃO: A BRIEF ANALYSIS. Revista Prevenção de Infecção E Saúde, 6(0). https://doi.org/10.26694/repis.v6i0.10477

Avesani, C. M.; Pereira, A. M. L. e Cuppari, L (2009). Nutrição: nas doenças crônicas não-transmissíveis. In L. Cuppari (Org.), Doença Renal Crônica. (267-330) Barueri, SP: Manole.

Bell, S., Campbell, J., McDonald, J., O’Neill, M., Watters, C., Buck, K., Cousland, Z., Findlay, M., Lone, N. I., Metcalfe, W., Methven, S., Peel, R., Almond, A., Sanu, V., Spalding, E., Thomson, P. C., Mark, P. B., & Traynor, J. P. (2020). COVID-19 in patients undergoing chronic kidney replacement therapy and kidney transplant recipients in Scotland: findings and experience from the Scottish renal registry. BMC Nephrology, 21(1). https://doi.org/10.1186/s12882-020-02061-8

Brasil (2020). Protocolo de manejo clínico do coronavírus (Covid-19) na Atenção Primária à Saúde. Ministério da Saúde, https://portalarquivos2.saude.gov.br/images/pdf/2020/marco/24/20200323-ProtocoloManejo-ver05.pdf

Cascella, M., Rajnik, M., Aleem, A., Dulebohn, S., & Di Napoli, R. (2021). Features, evaluation, and treatment of coronavirus (COVID-19). StatPearls. https://www.ncbi.nlm.nih.gov/books/NBK554776/

Cheng, Y., Luo, R., Wang, K., Zhang, M., Wang, Z., Dong, L., Li, J., Yao, Y., Ge, S., & Xu, G. (2020). Kidney disease is associated with in-hospital death of patients with COVID-19. Kidney International, 97(5). https://doi.org/10.1016/j.kint.2020.03.005

Cummings, M. J., Baldwin, M. R., Abrams, D., Jacobson, S. D., Meyer, B. J., Balough, E. M., Aaron, J. G., Claassen, J., Rabbani, L. E., Hastie, J., Hochman, B. R., Salazar-Schicchi, J., Yip, N. H., Brodie, D., & O’Donnell, M. R. (2020). Epidemiology, clinical course, and outcomes of critically ill adults with COVID-19 in New York City: a prospective cohort study. The Lancet, 395(10239), 1763–1770. https://doi.org/10.1016/s0140-6736(20)31189-2

Diao, B., Wang, C., Wang, R., Feng, Z., Zhang, J., Yang, H., Tan, Y., Wang, H., Wang, C., Liu, L., Liu, Y., Liu, Y., Wang, G., Yuan, Z., Hou, X., Ren, L., Wu, Y., & Chen, Y. (2021). Human kidney is a target for novel severe acute respiratory syndrome coronavirus 2 infection. Nature Communications, 12(1), 2506. https://doi.org/10.1038/s41467-021-22781-1

Dias, V. M. de C. H., Carneiro, M., Michelin, L., Vidal, C. F. de L., Costa, L. A. T. J. da, Ferreira, C. E. dos S., Welter, E. A. R., Lins, R. S., Kfouri, R., Costa, S. F., Cunha, C. A. da, Chebabo, A., Moura-Neto, J. A., Bahten, L. C. V., Oliveira, A. F., Silva, L. E. da, Ribeiro, H. S. de C., Ribeiro, R., Cohen, R., & Nascimento, M. M. do. (2020). Testes Sorológicos para COVID-19: Interpretação e Aplicações Práticas. Journal of Infection Control, 9(2), 90–101. https://jic-abih.com.br/index.php/jic/article/view/316/pdf

Farouk, S. S., Fiaccadori, E., Cravedi, P., & Campbell, K. N. (2020). COVID-19 and the kidney: what we think we know so far and what we don’t. Journal of nephrology, 33, 1-6. https://doi.org/10.1007/s40620-020-00789-y

Freire-Silva, J., Ferreira, H. dos S., Candeias, A. L. B., Pinho, M. A. B., & Oliveira, B. R. B. (2020). A utilização do planejamento territorial no combate da COVID-19: considerações sobre a situação dos leitos nos municípios de Pernambuco, Brasil. Vigilância Sanitária Em Debate, 8(2), 16–27. https://doi.org/10.22239/2317-269x.01546

Guo, Y.-R., Cao, Q.-D., Hong, Z.-S., Tan, Y.-Y., Chen, S.-D., Jin, H.-J., Tan, K.-S., Wang, D.-Y., & Yan, Y. (2020). The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak – an update on the status. Military Medical Research, 7(1). https://doi.org/10.1186/s40779-020-00240-0

Huang, C., Wang, Y., Li, X., Ren, L., Zhao, J., Hu, Y., Zhang, L., Fan, G., Xu, J., Gu, X., Cheng, Z., Yu, T., Xia, J., Wei, Y., Wu, W., Xie, X., Yin, W., Li, H., Liu, M., & Xiao, Y. (2020). Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. The Lancet, 395(10223), 497–506. https://doi.org/10.1016/s0140-6736(20)30183-5

IBGE – Instituto Brasileiro de Geografia e Estatística (2011). Sinopse do Censo Demográfico 2010. Rio de Janeiro: IBGE. https://biblioteca.ibge.gov.br/visualizacao/livros/liv49230.pdf.

IBGE – Instituto Brasileiro de Geografia e Estatística (2017). Pesquisa nacional por amostra de domicílios de 2001 a 2015. Microdados. Rio de Janeiro: IBGE.

KDIGO 2017 Clinical Practice Guideline Update for the Diagnosis, Evaluation, Prevention, and Treatment of Chronic Kidney Disease–Mineral and Bone Disorder (CKD-MBD). (2017). Kidney International Supplements, 7(1), 1–59. https://doi.org/10.1016/j.kisu.2017.04.001

Lely, A. T., Hamming, I., van Goor, H., & Navis, G. J. (2004). Renal ACE2 expression in human kidney disease. The Journal of Pathology: A Journal of the Pathological Society of Great Britain and Ireland, 204(5), 587-593. https://doi.org/10.1002/path.1670

Li, Y.-C., Bai, W.-Z., & Hashikawa, T. (2020). The neuroinvasive potential of SARS-CoV2 may be at least partially responsible for the respiratory failure of COVID-19 patients. Journal of Medical Virology, 92(6). https://doi.org/10.1002/jmv.25728

Liu, K., Fang, Y.-Y., Deng, Y., Liu, W., Wang, M.-F., Ma, J.-P., Xiao, W., Wang, Y.-N., Zhong, M.-H., Li, C.-H., Li, G.-C., & Liu, H.-G. (2020). Clinical characteristics of novel coronavirus cases in tertiary hospitals in Hubei Province. Chinese Medical Journal, 133(9), 1025–1031. https://doi.org/10.1097/cm9.0000000000000744

Lok, C. E., Huber, T. S., Lee, T., Shenoy, S., Yevzlin, A. S., Abreo, K., Allon, M., Asif, A., Astor, B. C., Glickman, M. H., Graham, J., Moist, L. M., Rajan, D. K., Roberts, C., Vachharajani, T. J., & Valentini, R. P. (2020). KDOQI Clinical Practice Guideline for Vascular Access: 2019 Update. American Journal of Kidney Diseases, 75(4), S1–S164. https://doi.org/10.1053/j.ajkd.2019.12.001

Maksimowski, N., Williams, V. R., & Scholey, J. W. (2020). Kidney ACE2 expression: Implications for chronic kidney disease. PLOS ONE, 15(10), e0241534. https://doi.org/10.1371/journal.pone.0241534

OPENDATASUS. Vigilância de Síndrome Respiratória Aguda Grave (SRAG) 23/11/2020. https://opendatasus.saude.gov.br/dataset/casos-nacionais/resource/54f5272b-259c-4f41-990d-e461a1d3a41c.

Pereira, A. S., Shitsuka, D. M., Parreira, F. J., & Shitsuka, R. (2018). Metodologia da pesquisa científica. Santa Maria, RS : UFSM, NTE. https://www.ufsm.br/app/uploads/sites/358/2019/02/Metodologia-da-Pesquisa-Cientifica_final.pdf

Poblete, G., Cox, W., Dasso, A., & Begher, S. (2021). Características epidemiológicas y clínicas de pacientes internados con COVID-19 en la Ciudad de Buenos Aires. Actualizaciones En Sida E Infectología, 29(105). https://doi.org/10.52226/revista.v29i105.53

Ronco, C., Reis, T., & Husain-Syed, F. (2020). Management of acute kidney injury in patients with COVID-19. The Lancet Respiratory Medicine, 8(7). https://doi.org/10.1016/s2213-2600(20)30229-0

Santos-Neto, A. G. dos, Santos, A. de F., Santos, J. R. dos, Alves, L. L., Ramos, A. C. S., Santana, A. A. M., Santos, I. D. D. dos, & Gaspar, L. M. do A. C. (2021). COVID-19: Metodologias de diagnóstico. Research, Society and Development, 10(5), e48810515114. https://doi.org/10.33448/rsd-v10i5.15114

Sesa-Pr. Secretaria de Saúde do Estado do Paraná (BR Informe epidemiológico Coronavírus (COVID-19). Curitiba: SESA; 2020. https://www.saude.pr.gov.br/sites/default/arquivos_restritos/files/documento/2020-12/informe_epidemiologico_09_12_2020.pdf.

Silva, F. da, Bettinelli, L. A., Bortoluzzi, E. C., Doring, M., Fortes, V. L. F., & Dobner, T. (2017). Terapia Renal Substitutiva: Perfil Sociodemográfico e Clínico Laboratorial de Paciente de um Serviço de Hemodiálise. J Nurs UFPE on Line, 11(9). https://doi.org/10.5205/reuol.11088-99027-5-ED.1109201703

Silva, A. W. C., Cunha, A. A., Alves, G. C., Corona, R. A., Dias, C. A. G. de M., Nassiri, R., Vedovelli, S., Vilhena, T. R. F., Favacho, V. B. C., Sousa, J. F., Araújo, M. H. M., Oliveira, E., Dendasck, C. V., & Fecury, A. A. (2020). Perfil epidemiológico e determinante social do COVID-19 em Macapá, Amapá, Amazônia, Brasil. Revista Científica Multidisciplinar Núcleo Do Conhecimento, 4. https://doi.org/10.32749/nucleodoconhecimento.com.br/saude/covid-19-em-macapa

Teich, V. D., Klajner, S., Almeida, F. A. S. de, Dantas, A. C. B., Laselva, C. R., Torritesi, M. G., Canero, T. R., Berwanger, O., Rizzo, L. V., Reis, E. P., & Cendoroglo, M. (2020). Epidemiologic and clinical features of patients with COVID-19 in Brazil. Einstein (São Paulo), 18. https://doi.org/10.31744/einstein_journal/2020ao6022

Teixeira Neto, F. (2012). Nutrição Clínica. Rio de Janeiro: Guanabara Koogam.

Tortonese, S., Scriabine, I., Anjou, L., Loens, C., Michon, A., Benabdelhak, M., Ouali, S., Morin, G., Laifi, M., Dobosziewicz, H., Guillet, M., Dekeyser, M., Nguyen, L. B. L., Grünenwald, A., Dang, J., Desbuissons, G., Becquemont, L., Snanoudj, R., Legendre, C., & Hebibi, H. (2020). COVID-19 in Patients on Maintenance Dialysis in the Paris Region. Kidney International Reports, 5(9), 1535–1544. https://doi.org/10.1016/j.ekir.2020.07.016

Wang, D., Hu, B., Hu, C., Zhu, F., Liu, X., Zhang, J., Wang, B., Xiang, H., Cheng, Z., Xiong, Y., Zhao, Y., Li, Y., Wang, X., & Peng, Z. (2020). Clinical Characteristics of 138 Hospitalized Patients with 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, China. JAMA, 323(11), 1061–1069. https://doi.org/10.1001/jama.2020.1585

Xiong, F., Tang, H., Liu, L., Tu, C., Tian, J.-B., Lei, C.-T., Liu, J., Dong, J.-W., Chen, W.-L., Wang, X.-H., Luo, D., Shi, M., Miao, X.-P., & Zhang, C. (2020). Clinical Characteristics of and Medical Interventions for COVID-19 in Hemodialysis Patients in Wuhan, China. Journal of the American Society of Nephrology, 31(7), 1387–1397. https://doi.org/10.1681/asn.2020030354

Published

24/12/2021

How to Cite

SILVA, C. P. da; BENVEGNÚ, D. M.; ZANELATTO, C.; NISHIYAMA, M. F. Covid-19: an analysis of reports of positive cases in the State of Paraná in 2020, with emphasis on chronic kidney disease. Research, Society and Development, [S. l.], v. 10, n. 17, p. e177101724154, 2021. DOI: 10.33448/rsd-v10i17.24154. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/24154. Acesso em: 24 jan. 2022.

Issue

Section

Health Sciences