Nutritional conduct in the care of Polycystic Ovary Syndrome manifestations
Keywords:Polycystic Ovary Syndrome; Effects; Diet; Treatment; Nutritional conduct.
The objective of this review was to evaluate the effects of nutritional patterns indicated for the management of Polycystic Ovary Syndrome (PCOS). For this purpose, a bibliographic search was carried out in the PubMed database, comprising articles published between 2018 and 2021, in English and Portuguese. A total of 1141 articles were found, and 610 articles were excluded for being unrelated to the topic studied or for not being freely available. Of the 531 articles, 41 were selected and 20 studies were included in the review. As a result, the studies suggest that nutritional interventions, such as low-carbohydrate (<45%) and low-glycemic index diets, supplementation of omega-3 and phenolic compounds, higher ingestion of legumes and vegetables, appear to have a beneficial effect, when adjusted to individual need, on clinical and biochemical manifestations in women with PCOS. The present study is in line with the evidence that a variety of balanced dietary approaches can and should be recommended for the management of these manifestations. However, the general principles of healthy eating, as recommended for the general population, are applicable to all women with PCOS. For these, it is not known so far whether or not there is limited evidence that any specific type of diet is better than another.
Barrea, L., Arnone, A., Annunziata, G., Muscogiuri, G., Laudisio, D., Salzano, C., Pugliese, G., Colao, A., & Savastano, S. (2019). Adherence to the Mediterranean Diet, Dietary Patterns and Body Composition in Women with Polycystic Ovary Syndrome (PCOS). Nutrients, 11(10), 2278. https://doi.org/10.3390/nu11102278
Calcaterra, V., Verduci, E., Cena, H., Magenes, V. C., Todisco, C. F., Tenuta, E., Gregorio, C., de Giuseppe, R., Bosetti, A., di Profio, E., & Zuccotti, G. (2021). Polycystic Ovary Syndrome in Insulin-Resistant Adolescents with Obesity: The Role of Nutrition Therapy and Food Supplements as a Strategy to Protect Fertility. Nutrients, 13(6), 1848. https://doi.org/10.3390/nu13061848
Darvishi, S., Rafraf, M., Asghari-Jafarabadi, M., & Farzadi, L. (2021). Synbiotic Supplementation Improves Metabolic Factors and Obesity Values in Women with Polycystic Ovary Syndrome Independent of Affecting Apelin Levels: A Randomized Double-Blind Placebo - Controlled Clinical Trial. International Journal of Fertility & Sterility, 15(1), 51–59. https://doi.org/10.22074/ijfs.2021.6186
Ganie, M. A., Sahar, T., Rashid, A., Wani, I. A., Nisar, S., Sathyapolan, T., Vishnubhatla, S., Ramakrishnan, L., Parvez, T., & Geer, I. (2019). Avaliação comparativa de biomarcadores de inflamação entre mulheres indianas com síndrome dos ovários policísticos (SOP) que consomem dieta vegetariana vs. dieta não vegetariana. Front Endocrinol (Lausanne), 10(2019), 10–699
Haidari, F., Banaei-Jahromi, N., Zakerkish, M., & Ahmadi, K. (2020). The effects of flaxseed supplementation on metabolic status in women with polycystic ovary syndrome: a randomized open-labeled controlled clinical trial. Nutrition Journal, 19(1), 8. https://doi.org/10.1186/s12937-020-0524-5
Hallajzadeh, J., Khoramdad, M., Karamzad, N., Almasi-Hashiani, A., Janati, A., Ayubi, E., Pakzad, R., Sullman, M. J. M., & Safiri, S. (2018). Metabolic syndrome and its components among women with polycystic ovary syndrome: a systematic review and meta-analysis. Journal of Cardiovascular and Thoracic Research, 10(2), 56–69. https://doi.org/10.15171/jcvtr.2018.10
Kazemi, M., Hadi, A., Pierson, R. A., Lujan, M. E., Zello, G. A., & Chilibeck, P. D. (2021). Effects of Dietary Glycemic Index and Glycemic Load on Cardiometabolic and Reproductive Profiles in Women with Polycystic Oçvary Syndrome: A Systematic Review and Meta-analysis of Randomized Controlled Trials. Advances in Nutrition (Bethesda, Md.), 12(1), 161-178. https://doi.org/10.1093/advances/nmaa092
Kazemi, M., Lalooha, F., Nooshabadi, M. R., Dashti, F., Kavianpour, M., & Haghighian, H. K. (2021). Randomized double blind clinical trial evaluating the Ellagic acid effects on insulin resistance, oxidative stress and sex hormones levels in women with polycystic ovarian syndrome. Journal of Ovarian Research, 14(1). https://doi.org/10.1186/s13048-021-00849-2
Kazemi, M., McBreairty, L. E., Chizen, D. R., Pierson, R. A., Chilibeck, P. D., & Zello, G. A. (2018). A Comparison of a Pulse-Based Diet and the Therapeutic Lifestyle Changes Diet in Combination with Exercise and Health Counselling on the Cardio-Metabolic Risk Profile in Women with Polycystic Ovary Syndrome: A Randomized Controlled Trial. Nutrients, 10(10), 1387. https://doi.org/10.3390/nu10101387
Kite, C., Lahart, I. M., Afzal, I., Broom, D. R., Randeva, H., Kyrou, I., & Brown, J. E. (2019). Exercise, or exercise and diet for the management of polycystic ovary syndrome: a systematic review and meta-analysis. Systematic Reviews, 8(1), 51. https://doi.org/10.1186/s13643-019-0962-3
Moran, L. J., Noakes, M., Clifton, P., Buckley, J., Brinkworth, G., Thomson, R., & Norman, R. J. (2019). Predictors of Lifestyle Intervention Attrition or Weight Loss Success in Women with Polycystic Ovary Syndrome Who Are Overweight or Obese. Nutrients, 11(3), 492. https://doi.org/10.3390/nu11030492
Saadati, N., Haidari, F., Barati, M., Nikbakht, R., Mirmomeni, G., & Rahim, F. (2021). The effect of low glycemic index diet on the reproductive and clinical profile in women with polycystic ovarian syndrome: A systematic review and meta-analysis. Heliyon, 7(11), e08338. https://doi.org/10.1016/j.heliyon.2021.e08338
Salek, M., Clark, C. C. T., Taghizadeh, M., & Jafarnejad, S. (2019). N-3 fatty acids as preventive and therapeutic agents in attenuating PCOS complications. EXCLI Journal, 18, 558–575. https://doi.org/10.17179/excli2019-1534
Shang, Y., Zhou, H., He, R., & Lu, W. (2021). Dietary Modification for Reproductive Health in Women With Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis. Frontiers in Endocrinology, 12, 735954. https://doi.org/10.3389/fendo.2021.735954
Simon, S. L., McWhirter, L., Diniz Behn, C., Bubar, K. M., Kaar, J. L., Pyle, L., Rahat, H., Garcia-Reyes, Y., Carreau, A.-M., Wright, K. P., Nadeau, K. J., & Cree-Green, M. (2019). Morning Circadian Misalignment Is Associated With Insulin Resistance in Girls With Obesity and Polycystic Ovarian Syndrome. The Journal of Clinical Endocrinology and Metabolism, 104(8), 3525–3534. https://doi.org/10.1210/jc.2018-02385
Síndrome dos ovários policísticos. São Paulo: Federação Brasileira das Associações de Ginecologia e Obstetrícia (FEBRASGO). 2018. 103p. (Série Orientações e Recomendações FEBRASGO, n.4, Comissão Nacional de Ginecologia Endócrina)
Willis, S. K., Wise, L. A., Wesselink, A. K., Rothman, K. J., Mikkelsen, E. M., Tucker, K. L., Trolle, E., & Hatch, E. E. (2020). Glycemic load, dietary fiber, and added sugar and fecundability in 2 preconception cohorts. The American Journal of Clinical Nutrition, 112(1), 27–38. https://doi.org/10.1093/ajcn/nqz312
Yonekura, T., Quintans, J. R., Soares, C. B., & Negri Filho, A. A. de. (2019). Revisão realista como metodologia para utilização de evidências em políticas de saúde: uma revisão integrativa. Revista Da Escola de Enfermagem Da USP, 53. https://doi.org/10.1590/s1980-220x2018037703515
Zhang, X., Zheng, Y., Guo, Y., & Lai, Z. (2019). The Effect of Low Carbohydrate Diet on Polycystic Ovary Syndrome: A Meta-Analysis of Randomized Controlled Trials. International Journal of Endocrinology, 2019, 4386401. https://doi.org/10.1155/2019/4386401
Zhou, L., Ni, Z., Cheng, W., Yu, J., Sun, S., Zhai, D., Yu, C., & Cai, Z. (2020). Characteristic gut microbiota and predicted metabolic functions in women with PCOS. Endocrine Connections, 9(1), 63–73. https://doi.org/10.1530/EC-19-0522
How to Cite
Copyright (c) 2021 Caroline Maria Vasconcelos Assunção; Luiza Marly Freitas de Carvalho
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.