Association between respiratory viruses and asthma in children and adolescents: a scoping review
DOI:
https://doi.org/10.33448/rsd-v11i1.24297Keywords:
Coinfection; Pediatrics; Prevention of diseases; Rhinoviruses; Hiss.Abstract
Asthma is a chronic inflammatory disease that affects the airways and causes symptoms such as dyspnea, wheezing and coughing. It estimated that there are about 339 million people living with asthma in the world and that the influence of microorganisms considered a risk factor for the onset of asthma in childhood. Therefore, this review aimed to analyze the relationship between exposure to respiratory viruses and the occurrence of asthma in children and adolescents. Were searches performed in the Pubmed and Science Direct databases for articles in English using the respiratory virus AND (children OR adolescence) AND (wheezing OR asthma) search strategy. Of the 2,717 articles found, only 17 were included in the review based on the considered inclusion and exclusion criteria. The results showed that Rhinovirus and Respiratory Syncytial Virus were the most prevalent in the articles found. Additionally, detections were found for Adenoviruses, Coronaviruses, Enteroviruses, Bocaviruses, Influenza, Metapneumoviruses and Parainfluenza, in addition to the presence of coinfection between viruses and bacteria. The findings in this review may help in the development of public health strategies to prevent exacerbations of viral-induced respiratory diseases, given that many of the infections caused by these agents are seasonal in nature.
References
Baillie, V. L., Olwagen, C. P., & Madhi, S. A. (2018). Review on Clinical and Molecular Epidemiology of Human Rhinovirus-Associated Lower Respiratory Tract Infections in African and Southeast Asian Children. Pediatr Infect Dis J., 37(7), 185-194. https://doi.org/10.1097/inf.0000000000001897
Barlotta, A., Pirillo, P., Stocchero, M., Donato, F., Giordano, G., Bont, L., Zanconato, S., Carraro, S., & Baraldi, E. (2019). Metabolomic Profiling of Infants With Recurrent Wheezing After Bronchiolitis. The Journal of infectious diseases, 219(8), 1216–1223. https://doi.org/10.1093/infdis/jiy659
Beasley, R., Semprini, A., & Mitchell, E. A. (2015). Risk factors for asthma: is prevention possible?. The Lancet, 386(9998), 1075-1085. https://doi.org/10.1016/s0140-6736(15)00156-7
Bedolla-Barajas, M., Montero, H., Morales-Romero, J., Landa-Cardeña, A., Díaz, J., Delgado-Figueroa, N., & Orozco-Alatorre, L. G. (2017). Prevalence of respiratory viruses in wheezing children not older than 24 months of age. Gac Med Mex., 153(3), 329-334.
Brooks, G. F. (2014). Microbiologia médica de Jawetz, Melnick e Adelberg (26 ed.). AMGH.
Cardoso, T. A., Roncada, C., Silva, E. R., Pinto, L. A., Jones, M. H., Stein, R. T., & Pitrez, P. M. (2017). Impacto da asma no Brasil: análise longitudinal de dados extraídos de um banco de dados governamental brasileiro. J Bras Pneumol., 43(3), 163-168.
Choi, E., Ha, K. S., Song, D. J., Lee, J. H., & Lee, K. C. (2018). Clinical and laboratory profiles of hospitalized children with acute respiratory virus infection. Korean J Pediatr., 61(6), 180-186. https://doi.org/10.3345/kjp.2018.61.6.180
Costa, E., Caetano, R., Werneck, G. L., Bregman, M., Araújo, D. V., & Rufino, R. (2018). Estimated cost of asthma in outpatient treatment: a real-world study. Rev Saúde Pública, 52(27), 1-11. https://doi.org/10.11606/S1518-8787.2018052000153
Costa, L. D., Costa, P. S., & Camargos, P. A. (2014). Exacerbation of asthma and airway infection: is the virus the villain?. Jornal de Pediatria, 90(6), 542-555. https://doi.org/10.1016/j.jped.2014.07.001
Filho, G. B. (2016). Bogliolo, Patologia (9 ed.). Guanabara Koogan.
García-García, M. L., Calvo, C., Rey, C., Díaz, B., Mollinero, M. M., Pozo, F., & Casas, I. (2017). Human metapnuemovirus infections in hospitalized children and comparison with other respiratory viruses. 2005-2014 prospective study. PLoS ONE, 12(3), Artigo e0173504. https://doi.org/10.1371/journal.pone.0173504
Gerhardsson, V. M., Gustafson, P., McCrae, C., Edsbäcker, S., & Johnston, N. (2017). Seasonal and geographic variations in the incidence of asthma exacerbations in the United States. Journal of Asthma, 54(8), 818-824. https://doi.org/10.1080/02770903.2016.1277538
Hürdum, S. H., Zhang, G., Khoo, S. K., Bizzintino, J., Franks, K. M., Lindsay, K., Keil, A. D., Cox, D. W., Goldblatt, J., Bochkov, Y. A., Gern, J., Ulrik, C. S., Souëf, P. N., & Laing, I. A. (2015). Recurrent rhinovirus detections in children following a rhinovirus-induced wheezing exacerbation: A retrospective study. International journal of pediatrics and child health, 3(1), 10-18. https://doi.org/10.12974/2311-8687.2015.03.01.2
Jackson, D. J., Sykes, A., Mallia, P., & Johnston, S. L. (2011). Asthma exacerbations: Origin, effect, and prevention. J Allergy Clin Immunol., 128(6):1165-1174. https://doi.org/10.1016/j.jaci.2011.10.024
Kato, M., Suzuki, K., Yamada, Y., Maruyama, K., Hayashi, Y., & Mochizuki, H. (2015). Virus detection and cytokine profile in relation to age among acute exacerbations of childhood asthma. Allergology international: official journal of the Japanese Society of Allergology, 64 Suppl, S64–S70. https://doi.org/10.1016/j.alit.2015.06.008
Kwon, J. M., Shim, J. W., Kim, D. S., Jung, H. L., Park, M. S., & Shim, J. Y. (2014). Prevalence of respiratory viral infection in children hospitalized for acute lower respiratory tract diseases, and association of rhinovirus and influenza virus with asthma exacerbations. Korean journal of pediatrics, 57(1), 29–34. https://doi.org/10.3345/kjp.2014.57.1.29
Leynaert, B., Le Moual, N., Neukirch, C., Siroux, V., & Varraso, R. (2019). Environmental factors favoring the development of asthma. Presse Med., 48(3), 262-273. https://doi.org/10.1016/j.lpm.2019.02.022
Liu, L., Pan, Y., Zhu, Y., Song, Y., Su, X., Yang, L., Li, M. (2017). Association between rhinovirus wheezing illness and the development of childhood asthma: a meta-analysis. BMJ Open, 7, Artigo e013034. http://doi.org/10.1136/bmjopen-2016-013034
Minor, T. E., Dick, E. C., DeMeo, A. N., Ouellette, J. J., Cohen, M., & Reed, C. E. (1974). Viruses as Precipitants of Asthmatic Attacks in Children. JAMA, 227(3), 292-298. http://doi.org/10.1001/jama.1974.03230160020004
Mummidi, P. S., Tripathy, R., Dwibedi, B., Mahapatra, A., & Baraha, S. (2017). Viral aetiology of wheezing in children under five. The Indian journal of medical research, 145(2), 189–193. https://doi.org/10.4103/ijmr.IJMR_840_15
Nenna, R., Ferrara, M., Nicolai, A., Pierangeli, A., Scagnolari, C., Papoff, P., Antonelli, G., Moretti, C., & Midulla, F. (2015). Viral load in infants hospitalized for respiratory syncytial virus bronchiolitis correlates with recurrent wheezing at thirty-six-month follow-up. The Pediatric Infectious Disease Journal, 34(10), 1131-1132. https://doi.org/10.1097/inf.0000000000000825
Neuman, Å., Hohmann, C., Orsini, N., Pershagen, G., Eller, E., Kjaer, H. F., Gehring, U., Granell, R., Henderson, J., Heinrich, J., Lau, S., Nieuwenhuijsen, M., Sunyer, J., Tischer, C., Torrent, M., Wahn, U., Wijga, A. H., Wickman, M., Keil, T., & Bergström, A. (2012). Maternal smoking in pregnancy and asthma in preschool children: a pooled analysis of eight birth cohorts. Am J Respir Crit Care Med., 186(10), 1037-1043.
Nicolai, A., Frassanito, A., Nenna, R., Cangiano, G., Petrarca, L., Papoff, P., Pierangeli, A., Scagnolari, C., Moretti, C., & Midulla, F. (2017). Risk Factors for Virus-induced Acute Respiratory Tract Infections in Children Younger Than 3 Years and Recurrent Wheezing at 36 Months Follow-Up After Discharge. Pediatr Infect Dis J., 36(2), 179-183. https://doi.org/10.1097/inf.0000000000001385
Porsbjerg, C., von Linstow, M. L., Ulrik, C. S., Nepper-Christensen, S., & Backer, V. (2006). Risk factors for onset of asthma: a 12-year prospective follow-up study. Chest., 129(2), 309-316. https://doi.org/10.1378/chest.129.2.309
Rady, H. I., & Kholy, A. E. (2018). Prevalence of Human rhinovirus infection in young children with acute wheezing. The Gazette of the Egyptian Paediatric Association, 66(2), 35–38. https://doi.org/10.1016/j.epag.2018.05.001
Régnier, S. A., Huels, J. (2013). Association Between Respiratory Syncytial Virus Hospitalizations in Infants and Respiratory Sequelae. The Pediatric Infectious Disease Journal, 32(8), 820-826. https://doi.org/10.1097/inf.0b013e31829061e8
Rosal, T., García-García, M. L., Calvo, C., Gozalo, F., Pozo, F., & Casas, I. (2016). Recurrent wheezing and asthma after bocavirus bronchiolitis. Allergologia et Immunopathologia, 44(5), 410-414. https://doi.org/10.1016/j.aller.2015.07.004
Silva, E. C. F. (2008). Bronchial Asthma. Revista do Hospital Universitário Pedro Ernesto, 7, 33-57. https://www.e-publicacoes.uerj.br/index.php/revistahupe/article/view/9249
Solé, D. (2008). Sibilância na infância. J Bras Pneumol., 34(6), 337-339. https://doi.org/10.1590/S1806-37132008000600001
Sun, H., Sun, Q., Jiang, W., Chen, Z., Huang, L., Wang, M., Ji, W., Shao, X., & Yan, Y. (2016). Prevalence of rhinovirus in wheezing children: a comparison with respiratory syncytial virus wheezing. Braz j Infect Dis., 20(2), 179–183. https://doi.org/10.1016/j.bjid.2015.12.005
Tórtora, R. P., Guimarães, M. A. A.M., Souza, L. M., Santos, I. A., Varella, R. B., Fátima, P. M. M., Cunha, A. J. L. A., & Sant' Anna, C. C. (2015). Adenovirus species C detection in children under four years of age with acute bronchiolitis or recurrent wheezing. Journal of Clinical Virology, 73, 77–80. https://doi.org/10.1016/j.jcv.2015.11.007
Wisniewski, J. A., McLaughlin, A. P., Stenger, P. J., Patrie, J., Brown, M. A., El-Dahr, J. M., Platts-Mills, T. A., Byrd, N. J., & Heymann, P. W. (2016). A comparison of seasonal trends in asthma exacerbations among children from geographic regions with different climates. Allergy and asthma proceedings, 37(6), 475–481. https://doi.org/10.2500/aap.2016.37.3994
WHO. (2021, 18 de novembro). Asthma. https://www.who.int/news-room/facts-in-pictures/detail/asthma.
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Copyright (c) 2022 Giselmo Pinheiro Lopes; Rose Daiana Cunha dos Santos; João Victor Ferreira Araújo; Vanessa Graziela da Cunha Medeiros; Alessandra Gomes Mesquita; Angela Falcai
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