Reviewing Treatment for Methicillin-Resistant Staphylococcus aureus Pneumonia
DOI:
https://doi.org/10.33448/rsd-v11i1.24338Keywords:
Pneumonia; Methicillin, Linezolid resistant Staphylococcus aureus; Vancomycin.Abstract
Introdução: O Staphylococcus aureus resistente à meticilina (MRSA) pode causar diversas infecções, tanto dermatológicas, quanto infecções invasivas, como pneumonia, empiema e sepse. Devido sua importância e patogenicidade, é considerado um problema de saúde pública mundial, o que implica em necessidade de pesquisar por esquemas terapêuticos mais eficientes. Especificamente para o tratamento de pneumonia por MRSA, à vancomicina e a linezolida são as principais drogas utilizadas. Objetivo: O objetivo principal deste estudo foi comparar os dois fármacos quanto a sua eficácia no tratamento da pneumonia por MRSA, por meio da revisão dos aspectos mais recentes da literatura. Metodologia: Por meio de revisão narrativa, foram averiguados os prós e contras de cada intervenção terapêutica, assim como os aspectos farmacológicos individuais e a fisiopatologia da infecção bacteriana em questão. Conclusão: Por fim, concluiu-se que a linezolida apresenta superioridade frente à vancomicina, com melhores taxas de redução de mortalidade e tempo de hospitalização, junto a menor risco de complicações e eventos adversos, além de maior flexibilidade terapêutica, melhor custo benefício e menores taxas de resistência.
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Copyright (c) 2022 Márcia Farsura de Oliveira; Caroline Silva de Araujo Lima; Rômulo Daniel Sanches; Jemerson Costa da Silva; Thaísa Munique Ferreira Costa de Oliveira; Isa Vitória Gonçalves Araújo; Rubenrhaon Alberto Paulino; Mona Khaled Abdul Rahim; Gabryelle Moreira Corrêa; Ana Gabrielly Masson Itacarambi; Gustavo Henrique Silva Ribeiro; Anderson Poubel Batista; Monique de Paula Pereira Grillo
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