Evaluation of the hematological and biochemical profiles of Giant Anteaters (Myrmecophaga tridactyla) with severe thermal burns: Report of six cases

Authors

DOI:

https://doi.org/10.33448/rsd-v11i2.24480

Keywords:

Anemia; SIRS; Thermal injury; Anteaters.

Abstract

Forest fires occur annually in the Pantanal Mato-grossense in periods of drought causing morbidit and mortality of numerous animal species, and the giant anteaters are among the main victims of these catastrophes. Due to the difficult breeding captivy of this specie, there are few data in the veterinary literature regarding the hematological and biochemical profiles of healthy giant anteaters and there is no description of the aletreations found in these animals with termal injuries caused by fire. Therefore, the objective was to evaluate the hematological and biochemical profiles of giant anteaters from areas on fire in the Pantanal (MT) in 2020, as well as to determine the most frequent laboratory alterations. In the Veterinary Clinical Pathology Laboratory of HOVET-UFMT, complete blood count and serum biochemistry of blood samples from six individuals of the specie Myrmecophaga tridactyla after hospital admission. Among the evaluated results, it was observed that: 83,3% (5/6) of the animals had hypochromic normocytic anemia on erythrograms, on white blood cell counts 66,7% (4/6) had left shift and neutropenia, in addition to other findings predominant in blood counts as total plasma hypoproteinemia observed in 100% (6/6) of individuals and thrombocytosis in 66,7% (4/6). Few changes were observed in serum biochemistry, unlike data found in human literature. It was concluded that giant anteaters with severe thermal burns show mainly laboratory alterations in the blood count and few biochemical alterations in a first post- rescue evaluation. Thus, stressing the need to perform these tests at various time intervals after injury to better understand the laboratory changes suffered by these patients, given that all individuals in this study died.

References

Amaral, B. P., Muller, D. C. M., Rakoski, A. S., & Basso, P. C. (2016). Manejo de queimaduras em pequenos animais. Medvep- Revista Científica de Medicina Veterinária- Pequenos Animais e Animais de Estimação, 14(44), 94-100.

Auger, C., Samadi, O., & Jeschke, M. G. (2017). The biochemical alterations underlyng post-burn hypermetabolism. Biochimica et Biophysica Acta, 1863(10), 2633-2644.

Araújo, G. R., Silva, P. M., Estrela, C. D., & Castro, A. L. S. (2015). Mamíferos de médio e grande porte em um fragmento florestal de Cerrado do município de Ipameri-GO. Multi-Science Journal, 1(1), 55-61.

Barcellos, L. G., Silva, A. P. P., Piva, J. P., Rech, L., & Brondani, T. G. (2018). Características e evolução de pacientes queimados admitidos em unidade de terapia intensiva pediátrica. Revista Brasileira de Terapia Intensiva, 30(3), 333-337.

Bateman, R. M., Sharpe, M. D., Singer, M., & Ellis, C. G. (2017). The Effect of Sepsis on the Erythrocyte. International Journal of Molecular Sciences, 18(9), 1-23.

Braga, M. S., Pantoja, L. D., Scerni, F. M., & Vasconcelos, F. C. (2015). Análise do consumo alimentar e das alterações biológicas de pacientes queimados internados em hospital de referência. Revista Brasileira de Queimaduras, 14(2) 125- 132.

Chen, Y.-F., Ma, H., Perng, C.-K., Liao, W. -C., Shih, Y. -C., Lin, C.-H., Chen, M. –C., Hsiao, F. –Y., & Wang, T. –H. (2020). Albumin supplementation may have limited effects on prolonged hypoalbuminemia in major burn patients: An outcome and prognostic factor analysis. Journal of the Chinese Medical Association, 83(2), 206-210.

Cubas, Z. S., Silva, J. C. R., & Catão-Dias, J. L. (2014). Tratado de Animais Selvagens (2a ed). São Paulo: Roca.

Diniz, M. F., & Brito, D. (2015). Protected areas effectiveness in maintaining viable giant anteater (Myrmecophaga tridactyla) populations in an agricultural frontier. Revista Natureza e Conservação, 13(2), 145-151.

Fang, F., Zhang. Y., Tang, J., Lunsford, L.D., Li, T., Tang, R., He, J., Xu, P., Faramand, A., Xu, J., & You, C. (2019). Association of Corticosteroid Treatment With Outcomes in Adult Patients With Sepsis. JAMA Internal Medicine, 179(2), 213-223.

Freitas, G. S., Carvalho, G. S. P., Sousa, L. O., Cassiano, R. P., Garcia Neto, M., & Filardi, R. S. (2018). Descrevendo o crescimento de um filhote de Tamanduá-Bandeira (Myrmecophaga tridactyla) (LINNAEUS, 1758). Archives of Veterinary Science, 23(3), 42-45.

Giordani, A. T., Sonobe, H. M., Guarini, G., & Stadler, D. V. (2016). Complicações em pacientes queimados: revisão integrativa. Revista Eletrônica Gestão & Saúde, 7(2), 535-548.

Guyton, A. C., & Hall, J. E. (2017). Tratado de Fisiologia Médica (13ª ed). Rio de Janeiro: Elsevier.

Hotchkiss, R. S., Moldawer, L. L., Opal, S. M., Reinhart, K., Turnbull, I. R., & Vincent, J. L. (2016). Sepsis and septic shock. Nature Reviews Disease Primers, 2(16045),1-21.

Hu, L., Wang, B., Hong, Y., Xu, L., Jiang, Y., Wang, C., Zhu, B., Yu, Q., Hou, W., Chen, Z., Zhu, F., Wu,G., & Sun, Y. (2021). Admission Neutrophil-Lymphocyte Ratio (NLR) Predicts Survival in Patients with Extensive. Burns, 47(3), 594-600.

Jain, N.C. (1993). Essentials of veterinary hematology. Philadelphia: Lea & Febiger.

Manning, J. (2018) Sepsis in the Burn Patient. Critical Care Nursing Clinics of North America, 30(3), 423-430.

Mariuzza, S. E., Machado, L., Schwengber, V. P., & Gonçalves, J. S. (2020). Terapia nutricional na recuperação de pacientes com queimaduras graves. Revista Destaques Acadêmicos, 12(3), 318-328.

Megahed, M. A., El-Helbawy, R. H., Gad, S. S., Mansour, M. M., & Elkandary, K. A. (2020). Base Deficit, Serum Albumin Level And Blood Haemoglobin Concentration Can Be Used As Predictor Factors For Mortality In Major Burn Patients. Annals of Burns and Fire Disasters, 33(3), 209-215.

Mokline, A., A, Abdenneji, A., I, Rahmani., L, Gharsallah, L., Tlaili, S., Harzallah, I., Gasri, B., Hamouda, R., & Messadi, A. A. (2017). Lactate: prognostic biomarker in severely burned patients. Annals of Burns and Fire Disasters, 30(1), 35-38.

Nielson, C. B., Duethman, N. C., Howard, J. M., Moncure, M., & Wood, J. G. (2017). Burns: Pathophysiology of systemic complications and current management. Journal of Burn Care & Research, 38(1), 469-481.

Oliveira, E. (2016). Hematologia, bioquímica e eletroforese de proteínas séricas de Tamanduás-bandeiras (Myrmecophaga tridactyla, LINNAEUS, 1758) em cativeiro. Dissertação de mestrado, Universidade Federal de Goiás –UFG, Goiânia, GO, Brasil. 81p.

Oliveira, W. J., Santos, A. L. Q., Souza, W. V., Custódio, A. E. I., Lux Hoppe, E. G., Tebaldi, J. H., & Rosalinski Moraes, F. (2020). Caracterização da fauna helmintológica de tamanduá-bandeira (Myrmecophaga tridactyla) e tamanduá-mirim (Tamandua tetradactyla) atropelados nas rodovias BR-050 e BR-455 (Minas Gerais, Brasil). Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 72(6), 2175-2185.

Rochwerg, B., Oczkowski, S.J., Siemieniuk, R.A.C., Agoritsas, T., Belley-Cote, E., D’Aragon, Frédérick., Duan, E., English, S., Keenan-Gossack, K., Alghuroba, M., Szczeklil, W., Menon, K., Alhazzani, W., Sevransky, J., Vandvik, P.O., Annane, D., & Guyatt, G. (2017). Corticosteroids in Sepsis: An Updated Systematic Review and Meta-Analysis. BMJ Open, 7(6), 1411-1420.

Silveira, R. C., Santos, P. P., Kutchak, F. M., & Cardoso, E. K. (2017). Perfil epidemiológico dos pacientes com lesão inalatória que foram atendidos em uma Unidade de Queimados de um Hospital de Pronto-Socorro. Revista Brasileira de Queimaduras, 16(3), 150-156.

Stockham, S. L & Scott, M. A. (2011). Fundamentos de Patologia Clínica Veterinária (2a ed.). Guanabara Koogan.

Thakkar, R. K., Diltz, Z., Drews, J. D., Wheeler, K. K., Shi, J., Devine, R., Fabia, R., & Hall, M. (2018). Abnormal lymphocyte response after pediatric thermal injury is associated with adverse outcomes. Journal of Surgical Research, 228, 221–227.

Thrall, M. A., Weiser, G., Allison, R. W & Campbell, T. W. (2015). Hematologia e Bioquímica Clínica Veterinária (2ª ed). São Paulo: Roca.

Venkatesh, B., Finfer, S., Cohen, J., Rajbhandari, Y., Arabi, Y., Bellomo, R., Correa, M., Glass, P., Harward, M., Joyce, C., Li, Q., McArthur, C., Perner, A., Rhodes, A., Thompson, K., Webb, S., & Myburgh, J. (2018). Adjunctive Glucocorticoid Therapy in Patients with Septic Shock. The New England Journal of Medicine, 378(9), 797-808.

Vorstenbosch, J. (2019). Queimaduras térmicas: Visão geral, fisiopatologia, quantificação da gravidade da queimadura. Medscape.com. https://emedicine.medscape.com/article/1278244-overview.

Wang, B., Hu, L., Chen, Y., Zhu, B., Kong, W., Zhu, Z., Wang, K., Yu, Q., Zhang, W., Wu, G., Sun, Y., & Xia, Z. (2021). Aspartate transaminase/alanine transaminase (De Ritis ratio) predicts survival in major burn patientes. Burns. https://doi.org/10.1016/j.burns.2021.08.006.

Published

01/02/2022

How to Cite

MAGALHÃES, T. B. S. .; MENDONÇA, A. J. .; ZORZO, C.; MORGADO, T. O. .; CORRÊA, S. H. R. .; PALEMO, A. L. P. .; NARDES, E. R. da S.; COSTA, K. S. . Evaluation of the hematological and biochemical profiles of Giant Anteaters (Myrmecophaga tridactyla) with severe thermal burns: Report of six cases. Research, Society and Development, [S. l.], v. 11, n. 2, p. e45911224480, 2022. DOI: 10.33448/rsd-v11i2.24480. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/24480. Acesso em: 19 apr. 2024.

Issue

Section

Agrarian and Biological Sciences