Analysis of infections caused by carbapenemase-producing gram-negative bacteria in a hospital in the Campos Gerais region

Authors

DOI:

https://doi.org/10.33448/rsd-v10i17.24819

Keywords:

Carbapenemases; Health-related infections; KPC; Risk factors.

Abstract

Objective: To determine the profile and prevalence of hospital infections caused by carbapenem-resistant Gram-negative bacteria related to healthcare. Methodology: This retrospective cross-sectional descriptive study (Yin, 2015) analyzed the profile of infections in a single public hospital by collecting data from electronic medical records. The collection included demographic data and infection-related clinical and laboratory findings. Results: We analyzed 193 acquisitions of Gram negative bacteria, 25 of which were by carbapenem-resistant microorganisms. Of these, the most common species detected was Klebsiella pneumoniae (56%, 14/25).  As for infections, the predominant hospital sector was the intensive care unit (56%, 14/25), mostly related to ventilator-associated pneumonia (40%, 10/25) and in patients submitted to some invasive procedure (72%, 18/25). About 50% of the patients had some adjacent health condition. Antimicrobial treatment prior to diagnosis was identified in 72% (19/25) of patients, with a predominance of betalactams (85.7%, 12/19) and after diagnosis, the majority used monotherapy (72%, 19/25). The impact of the infection was that 68% (17/25) were admitted to the intensive care unit, 40% (10/25) died, and 60% (15/25) were discharged. Conclusion: The results are in agreement with current literature and highlight the importance of prevention in combating the spread of these microorganisms in hospital environments.

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Published

27/12/2021

How to Cite

STÜKER, C. A. S.; BAIL, L. .; ITO, C. A. S.; MONTES, E. G. . Analysis of infections caused by carbapenemase-producing gram-negative bacteria in a hospital in the Campos Gerais region. Research, Society and Development, [S. l.], v. 10, n. 17, p. e227101724819, 2021. DOI: 10.33448/rsd-v10i17.24819. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/24819. Acesso em: 25 jan. 2022.

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Health Sciences