Study of the use of Benzodiazepines in a public institution in Teresina-PI
DOI:
https://doi.org/10.33448/rsd-v11i1.24839Keywords:
Benzodiazepine; Anxiolytic; Anxiety.Abstract
Benzodiazepines are the most used anxiolytics for the treatment of some public health problems, especially by patients who receive assistance in CAPS, but they can have dangerous effects when taken improperly. Thus, the study aimed to evaluate the Brazilian context of availability and consumption of benzodiazepines, from the point of view of users of CAPS in the city of Teresina-PI, health professionals and the dispensing of these drugs. The research was carried out at CAPS in the municipality of Teresina-PI between August and September 2021. All results were supported by approval by the ethics committee of the UNINOVAFAPI university center, the information being collected through questionnaires sent via email or whatsapp . As a profile, there was a majority of women aged 51 to 62 years, single, complete elementary school and with 3 other members in the household. As for the reasons for starting to use medication, the combination of anxiety, depression and insomnia was observed in 66.2% of patients. There was a majority of clonazepam consumption by patients among benzodiazepines. Overall, the dosage of 2mg once a day in the evening or at night was the most used dosage. Modification of the use or withdrawal of medication from patients was also observed, this measure being often taken by the user, without medical recommendation.
References
Airagnes, G., Lemogne, C., Renuy, A., Goldberg, M., Hoertel, N., Roquelaure, Y., ... & Zins, M. (2019). Prevalence of prescribed benzodiazepine long-term use in the French general population according to sociodemographic and clinical factors: findings from the CONSTANCES cohort. BMC Public Health, 19(1), 1-9.
Bernard, M. M. T., Luc, M., Carrier, J. D., Fournier, L., Duhoux, A., Côté, E., ... & Roberge, P. (2018). Patterns of benzodiazepines use in primary care adults with anxiety disorders. Heliyon, 4(7), e00688.
de Carvalho, M. C. M. (2021). Construindo o saber:: Metodologia científica-Fundamentos e técnicas. Papirus Editora.
Deka, R., Bryan, C. J., LaFleur, J., Oderda, G., Atherton, A., & Stevens, V. (2018). Benzodiazepines, health care utilization, and suicidal behavior in veterans with posttraumatic stress disorder. The Journal of clinical psychiatry, 79(6), 0-0.
Fride Tvete, I., Bjørner, T., & Skomedal, T. (2015). Risk factors for excessive benzodiazepine use in a working age population: a nationwide 5-year survey in Norway. Scandinavian journal of primary health care, 33(4), 252-259.
Gil, A. C. (2008). Métodos e técnicas de pesquisa social. 6. ed. Ediitora Atlas SA.
Hernandez, I., He, M., & Zhang, Y. (2018). Comparing state, regional, and local variation in concurrent opioid and benzodiazepine use. Drug and alcohol dependence, 191, 141-144.
Herrera-Gómez, F., Gutierrez-Abejón, E., Criado-Espegel, P., & Álvarez, F. J. (2018). The problem of benzodiazepine use and its extent in the driver population: a population-based registry study. Frontiers in pharmacology, 9, 408.
Jakobsen, L. S., Georgiadis, S., Nielsen, B. F., Bokkers, B. G., Boriani, E., Duedahl-Olesen, L., ... & Pires, S. M. (2018). Probabilistic approach for assessing cancer risk due to benzo [a] pyrene in barbecued meat: Informing advice for population groups. PloS one, 13(11), e0207032.
Laforgue, E. J., Jobert, A., Rousselet, M., Grall‐Bronnec, M., FAN network, Jolliet, P., ... & Victorri‐Vigneau, C. (2020). Do older people know why they take benzodiazepines? A national French cross‐sectional survey of long‐term consumers. International journal of geriatric psychiatry, 35(8), 870-876.
Luta, X., Bagnoud, C., Lambiris, M., Decollogny, A., Eggli, Y., Le Pogam, M. A., ... & Marti, J. (2020). Patterns of benzodiazepine prescription among older adults in Switzerland: a cross-sectional analysis of claims data. BMJ open, 10(1), e031156.
Muzaale, A. D., Daubresse, M., Bae, S., Chu, N. M., Lentine, K. L., Segev, D. L., & McAdams-DeMarco, M. (2020). Benzodiazepines, codispensed opioids, and mortality among patients initiating long-term in-center hemodialysis. Clinical journal of the American Society of Nephrology, 15(6), 794-804.
Osler, M., & Jørgensen, M. B. (2020). Associations of benzodiazepines, Z-drugs, and other anxiolytics with subsequent dementia in patients with affective disorders: a nationwide cohort and nested case-control study. American Journal of Psychiatry, 177(6), 497-505.
Sonnenberg, C. M., Bierman, E. J., Deeg, D. J., Comijs, H. C., Van Tilburg, W., & Beekman, A. T. (2012). Ten-year trends in benzodiazepine use in the Dutch population. Social psychiatry and psychiatric epidemiology, 47(2), 293-301.
Sun, G. Q., Zhang, L., Zhang, L. N., Wu, Z., & Hu, D. F. (2019). Benzodiazepines or related drugs and risk of pneumonia: A systematic review and meta‐analysis. International journal of geriatric psychiatry, 34(4), 513-521.
Torres-Bondia, F., de Batlle, J., Galván, L., Buti, M., Barbé, F., & Piñol-Ripoll, G. (2020). Trends in the consumption rates of benzodiazepines and benzodiazepine-related drugs in the health region of Lleida from 2002 to 2015. BMC Public Health, 20, 1-9.
Victorri‐Vigneau, C., Laforgue, E. J., Grall‐Bronnec, M., Guillou‐Landreat, M., Rousselet, M., Guerlais, M., ... & Jolliet, P. (2021). Are seniors dependent on benzodiazepines? A national clinical survey of substance use disorder. Clinical Pharmacology & Therapeutics, 109(2), 528-535.
Vozoris, N. T. (2019). Benzodiazepine and opioid co-usage in the US population, 1999–2014: An exploratory analysis. Sleep, 42(4), zsy264.
Wang, M. T., Wang, Y. H., Chang, H. A., Tsai, C. L., Yang, Y. S., Lin, C. W., ... & Hsu,
Y. J. (2017). Benzodiazepine and Z-drug use and risk of pneumonia in patients with chronic kidney disease: a population-based nested case-control study. PloS one, 12(7), e0179472.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 Gustavo Do Vale Batista; Glaubert Damon da Silva Santos; Williams Cardec da Silva
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.