Treatment of hemangiomas in the head and neck region: integrative literature review

Authors

DOI:

https://doi.org/10.33448/rsd-v11i1.25236

Keywords:

Hemangioma; Vascular tissue neoplasms; Sclerotherapy.

Abstract

This study aimed to identify the main forms of treatment for head and neck hemangiomas. This is an integrative literature review, whose guiding question was the therapeutic approach to hemangiomas. A bibliographic survey was carried out in the Scielo and Pubmed databases, between the years 2009 to 2019. The search resulted in the selection of 28 articles, after which the following eligibility criteria were investigated: open access, publications in Portuguese, English or Spanish and studies whose titles and abstracts were in line with the purpose of this review. At the end, 5 articles were selected. Gray literature and duplicates were excluded. Upon critical analysis of the studies, it was estimated that only 10 to 20% of hemangiomas require treatment. Therapeutic options for hemangioma are diverse, varying according to the characteristics of the patients and the peculiarities of the lesion, such as location, size, evolutionary stage and nature, arterial or venous. The treatment of minor and peripheral lesions consists mainly of sclerotherapy and surgical excision. On the other hand, larger and/or intraosseous lesions require previous embolization followed by surgical removal. There are reports of the use of drugs, such as propranolol and systemic corticosteroids, in addition to laser therapy, cryotherapy and electrocautery. Hemangiomas in the head and neck region are complex, relatively common pathologies and the therapy must be directed individually, according to the peculiarities of each case.

References

Araújo Filho, V. J. F., Cernea, C. R., & Brandão, L. G. (2013). Manual do residente de cirurgia de cabeça e pescoço. (2a ed.), Manole.

Ataş, E., Koç, O., & Artık, H. A. (2017). Clinical features and treatment results in children with hemangioma. Turk J Pediatr, 59 (3), 254-260. https://doi.org/10.24953/turkjped.2017.03.004

Azma, E., & Razaghi, M. (2018). Laser Treatment of Oral and Maxillofacial Hemangioma. J Lasers Med Sci, 9 (4), 228-232. https://doi.org/10.15171/jlms.2018.41

Bonini, F. K., Bellodi, F. S., & Souza, E. M. (2011). Hemangioma infantil tratado com propanolol. An Bras Dermatol, 86 (04), 763-766. https://doi.org/10.1590/S0365-05962011000400022

Cardoso, C. L., Fernandes, L. M. P. S. R., Rocha, J. F., Gonçalves, E. S., Júnior, O. F., & Taveira, L. A. A. (2010). Abordagem cirúrgica de hemangioma intraoral. Odontol Clin Cient, 9 (02), 177-180.

Crisan, B. V., Baciut, M., Baciut, G., Campian, R. S., & Crisan, L. (2010). Laser treatment in oral and maxillofacial hemangioma and vascular malformations. TMJ. 60 (1), 34-38.

DeHart, A., & Richter, G. (2019). Hemangioma: Recent Advances. F1000Res, 18 (08), 01-06. https://doi.org/10.12688/f1000research.20152.1

Jin, W. W., Tong, Y., Wu, J-M., Quan, H-H., & Gao, Y. (2020). Observation on the effects of 595- nm pulsed dye laser and 755- nm long-pulsed alexandrite laser on sequential therapy of infantile hemangioma. J Cosmet Laser Ther, 22 (3), 159-164. https://doi.org/10.1080/14764172.2020.1783452

Koh, S. P., Leadbitter, P., Smithers, F., & Tan, S. T. (2020). β-blocker therapy for infantile hemangioma. Expert Rev Clin Pharmacol, 13 (8), 899-915. https://doi.org/10.1080/17512433.2020.1788938

Leung, A. K. C., Lam, J. M., Leong, K. F., & Hon, K. L. (2021). Infantile hemangioma: an updated review. Curr Pediatr Rev, 17 (1), 55-69. https://doi.org/ 10.2174/1573396316666200508100038.

Marqueling, A. L., Oza, V., Frieden, I. J., & Puttgen, K. B. (2013). Propranolol and infantile hemangiomas four years later: a systematic review. Pediatr Dermatol, 30 (2), 182-191. https://doi.org/10.1111/pde.12089

Moyakine, A. V., Kerstjens, J. M., Koulil, S. S-v. & Vleuten, C. J. M. (2016). Propranolol treatment of infantile hemangioma (IH) is not associated with developmental risk or growth impairment at age 4 years. J Am Acad Dermatol, 75 (1), 59-63. https://doi.org/10.1016/j.jaad.2016.02.1218

Pereira, A. S., Shitsuka, D. M., Parreira, F. J. & Shitsuka, R. (2018). Metodologia da Pesquisa Científica. UFSM.

Pitta, G. B. B., & Gomes, R. R. (2009). Tratamento de hemangioma ulcerado: relato de caso. J Vasc Bras, 8 (03), 263-266. https://doi.org/10.1590/S1677-54492009005000010

Queiroz, S. I. M. L., Assis, G. M., Silvestre, V. D., Germano, A. R., & Silva, J. S. P. (2014). Tratamento de hemangioma oral com escleroterapia: relato de caso. J Vasc Bras, 13 (03), 249-253. https://doi.org/10.1590/jvb.2014.035

Sahin, B., Sonmez, S., Yilmazbayhan, E. D., & Orhan, K. S. (2019). Cavernous hemangioma in unusual location: pterygopalatine fossa. Braz J Otorhinolaryngol, 85 (01), 121- 124. https://doi.org/10.1016/j.bjorl.2016.02.003

Sakhiya, J., Sakhiya J, D., Virmani, N., Patel, A., Daruwala, F., & Dudhatra, N. A challenging case of cavernous hemangioma of the face treated with the combination of cryotherapy, laser, and dermatosurgery. J Clin Aesthet Dermatol, 13 (8), 14-16.

Satterfield, K. R., & Chambers, C. B. (2019). Current treatment and management of infantile hemangiomas. Surv Ophthalmol, 64 (5), 608-618. https://doi.org/ 10.1016/j.survophthal.2019.02.005

Smithson, S. L., Rademaker, M., Adams, S., Bade, S., Bekhor, P., Davidson, S., & Phillips, R. (2017). Consensus statement for the treatment of infantile haemangiomas with propranolol. Australas J Dermatol, 58 (2), 155-159. https://doi.org/10.1111/ajd.12600

Tiemann, L., & Hein, S. (2020). Infantile Hemangioma: A review of current pharmacotherapy treatment and practice pearls. J Pediatr Pharmacol Ther, 25 (7), 586-599. https://doi.org/10.5863/1551-6776-25.7.586.

Wang, Q., Xiang, B., Chen, S., & Ji, Y. (2019). Efficacy and safety of oral atenolol for the treatment of infantile haemangioma: A systematic review. Australas J Dermatol, 60 (3), 181-185. https://doi.org/10.1111/ajd.12966

Yang, H., Hu, D-L., Shu, Q., & Guo, X-D. (2019). Efficacy and adverse effects of oral propranolol in infantile hemangioma: a meta-analysis of comparative studies. World J Pediatr, 15 (6), 546-558. https://doi.org/10.1007/s12519-019-00285-9

Published

11/01/2022

How to Cite

SAMPAIO, D. B.; LIMA, W. P. de; MATIAS, I. de S.; SARAIVA, I. S.; FERREIRA, M. L.; RAMOS, V. M.; RIBEIRO, P. J. T. Treatment of hemangiomas in the head and neck region: integrative literature review. Research, Society and Development, [S. l.], v. 11, n. 1, p. e43811125236, 2022. DOI: 10.33448/rsd-v11i1.25236. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/25236. Acesso em: 23 nov. 2024.

Issue

Section

Health Sciences