Occurrence of otoneurological signs and symptoms in people living with HIV/AIDS: Integrative review

Authors

DOI:

https://doi.org/10.33448/rsd-v11i2.26002

Keywords:

HIV; Vestibular function tests; Vertigo; Antiretroviral therapy; Highly active; Vestibular diseases.

Abstract

Introduction: There is a discussion of whether HIV/AIDS or antiretroviral treatment is responsible for generalized clinical manifestations involving the auditory system and/or the vestibular system. Objective: To conduct an integrative review on the occurrence of otoneurological signs and symptoms in people living with HIV/AIDS. Method:  Utilizing the PICOS criterion to answer the following question: Are HIV/AIDS responsible for generalized clinical manifestations involving the vestibular system? Data collection from the databases:   Embase/Elsevier; Lilacs; PubMed; Scopus and Web Of Science, from 2010 to 2021. The following were included:  complete articles published Portuguese, English and Spanish, case-control study, cohort study, pilot study, with longitudinal and cross-sectional design, which report otoneurological alterations in people living with HIV/AIDS who underwent vertigo and/or dizziness tests. The key words were based on Decs - Descriptors in Health Sciences - and Mesh Terms in English. The following studies were excluded: abstracts, congress annals, case reports, studies that have a population under the age of 10 years and over 50 years, articles on HIV associated with other basic pathologies, Review articles. Results:  The research resulted in 735 studies identified in the databases   and after the application of inclusion criteria, 14 articles remained for descriptive analysis. Conclusion: After the conclusion of this literature review, it was possible to observe that there is no consensus in the literature on the effects of the use of antiretroviral therapy on the vestibular system of people living with HIV (PVHIV) or with immunodeficiency syndrome (AIDS).

References

Agu, K., & Oparah, A. (2013) Adverse drug reactions to antiretroviral therapy: Results from spontaneous reporting system in Nigeria. Perspectives in Clinical Research, 4(2) 117. 10.4103/2229-3485.111784

Berner, K, Strijdom, H., Essop, M. F., Webster, I., Morris, L., & Louw, Q. (2019) Fall History and Associated Factors Among Adults Living With HIV-1 in the Cape Winelands, South Africa: Na Exploratory Investigation. Open Forum Infectious Diseases, 6 (10) 1-7. 10.1093/ofid/ofz401

Cohen, H. S., Cox, C., Springer, G., Hoffman, H. J., Young. M. A., Margolick, J. B., & Plankey, M. W. (2012) Prevalence of Abnormalities in Vestibular Function and Balance among HIV Seropositive and HIV-Seronegative Women and Men. PLoS ONE 7(5), 5-11. 10.1371/journal.pone.0038419

Cohen H.S.; Plankey, M. W.; & Sangi-Haghpeykar, H. (2021) Vestibular Impairments on Objective Diagnostic Tests in HIV+ Women and Control Men and Women. Laryngoscope, 131(7) E2318–E2322, 2021. 10.1002/lary.29466

Erlandson, K. M. et al. (2012) Risk Factors for Falls in HIV-Infected Persons. J Acquir Immune Defic Syndr, 61(4), 484–489. 10.1097/QAI.0b013e3182716e38

Erlandson, K. M. et al. (2016) Fall Frequency among Men and Women with or at Risk for HIV Infection. HIV Med, 17(10), 740–748. 10.1111/hiv.12378.

Fokouo, J. V. F., Vokwely, J. E. E., Noubiap, J. J. N., Nouthe, B. E., Zack, J., Ngom, E. S. M. et al. (2015) Effect of HIV infection and highly active antiretroviral therapy on hearing function: A prospective case-control study from Cameroon. JAMA Otolaryngology - Head and Neck Surgery 141(5) 436–441. 10.1001/jamaoto.2015.125

Guimarães, M. D. C., Carneiro, M., Abreu, D. M. X., & França, E. B. (2017) Mortalidade por HIV/Aids no Brasil, 2000-2015: Motivos para preocupação? Revista Brasileira de Epidemiologia, (20) 182–190. 10.1590/1980-5497201700050015

Heinze, B. M, Vinck, B. M., Hofmeyr, L. M., & Swanepoel, W. (2014) Vestibular involvement in adults with HIV/AIDS. Auris Nasus Larynx (41) 160–168. http://dx.doi.org/10.1016/j.anl.2013.08.003

Heinze, B. M., Swanepoel, D. W., & Hofmeyr, L. M. (2011) Systematic review of vestibular disorders related to human immunodeficiency virus and acquired immunodeficiency syndrome. Journal of Laryngology and Otology 125(9) 881-890. 10.1017/S0022215111001423

Heinze, B. M., Vinck, B. M., & Swanepoel, D. W. (2014) Does the human immunodeficiency vírus influence the vestibulocollic reflex pathways? A comparative study. The Journal of Laryngology & Otology, 128, 772-779. 10.1017/S0022215114001996

Mahomed W., Heinze B.M., Vinck, B. H. M. E., Stoltz A. (2020) Auditory, video head impulse test and vestibular evoked myogenic potentials findings in adults with human immunodeficiency vírus. Auris Nasus Larynx, 47(3) 367–376. https://doi.org/10.1016/j.anl.2019.11.006

Matas, C. G., Samelli, A. G., Magliaro, F. C. L., & Segurado, A. (2018) Audiological and electrophysiological alterations in HIV-infected individuals subjected or not to antiretroviral therapy. Brazilian Journal of Otorhinolaryngology 84(5) 574–582. http://dx.doi.org/10.1016/j.bjorl.2017.07.003

Mathews, S. S., Albert, R.R., & Job, A. (2012) Audio-vestibular function in human immunodeficiency virus infected patients in India. Indian J Sex Transm Dis AIDS, 33(2) 98-101. 10.4103/0253-7184.102115.

Millar, A.; Joubert, K.; & Naude, A. (2021) Prevalence of Peripheral Vestibular Impairment in Adults with Human Immunodeficiency Virus. J Audiol Otolog, 25(1) 36-42. https://doi.org/10.7874/jao.2020.00164

Nguy, P. L, Ware D. C., & Plankey, M. (2021) Diagnostic Value of Screening Questions for Vestibular Dysfunction in HIV Disease: A Pilot Study. Georgetown Medical Review, 1-9. 10.52504/001c.21372

Rosario, M. G. (2020) Early signs of standing postural instability in asymptomatic people living with HIV. HIV AIDS Rev 19(3) 193-198. https://doi.org/10.5114/hivar.2020.99680

Ryan, A. S., Roy, A., & Oursler, K. K. (2019) Gait and Balance Biomechanics in Older Adults With and Without Human Immunodeficiency Virus. AIDS Research And Human Retroviruses 35(11-12) 1089-1094. 10.1089/aid.2019.0102

Shangase, K, K. (2018) Vestibular function in a group of adults with HIV/AIDS on haart. African Journal of Infectious Diseases 12(1) 7–14. 10.21010/ajid.v12i1.2

Shangase, K, K., & Van Rie., K. J. (2017) Pathological vestibular symptoms presenting in a group of adults with HIV/AIDS in Johannesburg, South Africa. Southern African Journal of Infectious Diseases 32(2) 43–53. 10.4102/sajid.v32i2.53

Yang, T. H., & Oh, S. Y. (2014) Geotropic central paroxysmal positional nystagmus in a patient with human immunodeficiency virus encephalopathy. Journal of Neuro-Ophthalmology 34(2) 159–161. 10.1097/WNO.0000000000000094

Published

04/02/2022

How to Cite

SALGUEIRO, F. H. D. .; SANTOS, T. M. M. Occurrence of otoneurological signs and symptoms in people living with HIV/AIDS: Integrative review. Research, Society and Development, [S. l.], v. 11, n. 2, p. e51411226002, 2022. DOI: 10.33448/rsd-v11i2.26002. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/26002. Acesso em: 26 nov. 2024.

Issue

Section

Review Article