Seroconversion related to Human T-Cell Lymphotropic Virus (HTLV) in a blood bank: a bibliometric study




Bibliometrics; Seroconversion; Lymphotropic virus; Blood bank; Prevalence.


The first human retrovirus isolated was the Human Cell Lymphotropic Virus (HTLV), belonging to the Retroviridae family, which infects TCD4+/TCD8+ cells. In a blood bank, seroconversion of donors by this virus is investigated by blood surveillance and some studies have shown that, despite the reduction of transfusion-transmitted diseases, the rate of seroconversion has increased. Aim: To define the portfolio of articles on HTLV seroconversion in blood banks. Methodology: This documentary-based study is based on bibliometric methodology, which uses quantitative scientific analysis methods. Data collection for this article was carried out in October and November 2021, in the Web of Science database, a platform that provides a wide range of scientific data for many academic disciplines. Results And Discussions: A low incidence of seroconversion to HTLV, either type 1 or 2, was found in blood banks. The authors described that the seroconversion rate is not high due to the methods used as barriers to transfusion safety, which are the clinical, serological, and immunological screening, methodologies used and standardized in all blood banks. Conclusion: This study allows us to help the scientific community with a documentary portfolio on the subject through mathematical and statistical aspects, the bibliometric indexes.


Brazil. (2016). Ordinance n. 158, of February 4, 2016. Redefines the technical regulation of hemotherapeutic procedures. Ministry of Health.

Brazil. (2017). Consolidation Ordinance no 5 of September 28, 2017. Consolidation of the norms on health actions and services of the Unified Health System. Ministry of Health, 926.

Brazil, M. da S. (2020). Epidemiologic Bulletin HIV / Aids | 2020. Secretariat of Health Surveillance, 1, 68.

Brown, D. (2020). A Review of the PubMed PICO Tool: Using Evidence-Based Practice in Health Education. Health Promotion Practice, 21(4), 496–498.

Caterino-de-araujo, A. (2021). Diagnóstico molecular de vírus T-linfotrópico humano ( HTLV ): histórico e estado da arte * Molecular diagnosis of human T-lymphotropic virus ( HTLV ): history and state of the art. 18(212), 14–62.

Cook, L., Melamed, A., Yaguchi, H., & Bangham, C. R. (2017). The impact of HTLV-1 on the cellular genome. Current Opinion in Virology, 26, 125–131.

Da Silva Garcia, I. F., & Hennington, É. A. (2019). HTLV: A stigmatizing infection? Cadernos de Saude Publica, 35(11), 1–14.

Guedes, V. L. S., & Borschiver, S. (2005). Bibliometrics: A Statistical Tool for Information and Knowledge Management, in Information, Communication and Information Systems. CINFORM - National Meeting of Information Science, 1–18.

Hewitt, P. E., Davison, K., Howell, D. R., & Taylor, G. P. (2013). Human T-lymphotropic virus lookback in NHS Blood and Transplant (England) reveals the efficacy of leukoreduction. Transfusion, 53(10), 2168–2175.

Iwanaga, M. (2020). Epidemiology of HTLV-1 Infection and ATL in Japan: An Update. Frontiers in Microbiology, 11(May), 1–11.

Martinez, M. P., Al-Saleem, J., & Green, P. L. (2019). Comparative virology of HTLV-1 and HTLV-2. Retrovirology, 16(1), 1–12.

Palareti, G., Legnani, C., Cosmi, B., Antonucci, E., Erba, N., Poli, D., Testa, S., & Tosetto, A. (2016). Comparison between different D-dimer cutoff values to assess the individual risk of recurrent venous thromboembolism: Analysis of results obtained in the DULCIS study. International Journal of Laboratory Hematology, 38(1), 42–49.

Pitanga, Â. F. (2020). Pesquisa Qualitativa Ou Pesquisa Quantitativa : Refletindo Sobre As Decisões Na Seleção De Determinada Abordagem Qualitative Research Or Quantitative Research : Reflecting On Decisions In Selecting A Certain Approach 1 Initial Considerations : A Brief pa. 184–201.

Rodrigues, C., & Godoy Viera, A. F. (2016). Bibliometric studies on the scientific production of Information and Communication Technologies in libraries. InCID: Journal of Information Science and Documentation, 7(1), 167.

Turato, E. R. (2005). Qualitative and quantitative methods in health care: definitions, differences, and their research objects. Journal of Public Health, 39(3), 507–514.




How to Cite

TIAGO, A. C. da S. .; CABRAL, L. J. B. .; QUINTAL, J. da S. .; CRUZ, J. de L. .; PINHEIRO, J. E. .; VALOIS, R. C. . Seroconversion related to Human T-Cell Lymphotropic Virus (HTLV) in a blood bank: a bibliometric study. Research, Society and Development, [S. l.], v. 11, n. 7, p. e21411726295, 2022. DOI: 10.33448/rsd-v11i7.26295. Disponível em: Acesso em: 4 mar. 2024.



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