Development of the Hemomonitor with an alert system for the patient using blood componentes

Authors

DOI:

https://doi.org/10.33448/rsd-v11i3.26300

Keywords:

Hemotherapy service; Blood component transfusion; Transfusion reaction; Software; Information systems; Clinical decision support systems.

Abstract

Objective: To develop the Hemomonitor software module with an alert system for monitoring patients using blood components. Methodology: This is an applied research carried out in a University Hospital, whose methodological trajectory followed three steps: 1) Characterization of the transfusion process at the study site; 2) Update on available software on the subject through a literature review; 3) Development of updated software based on specialized literature. Results: The flows of activities performed were triggered from the extraction of multivariate data from the systems, AGHUx and +Exames, used by the institution, to transform them into information. In addition, aiming at its operation, it was necessary to parameterize the alterations of the laboratory tests, to certify the HC prescription with the signature of the doctor responsible for the patient, to build a HC request sequencing, to allow the sharing of information and interface between the sectors, to standardize the supporting exams upon suspicion of transfusion, identify the patient's sample and the HC bag in an appropriate way with the legislation, parameterize the reports for the compatibility tests, allow traceability, parameterize changes in vital signs to establish a temporal link, define the audit trails, train teams in terms of speed of processes, efficiency and substantial use of resources. Conclusion: The implementation of the Hemomonitor module and its application in a pilot unit made it possible to observe that its use can improve the real-time monitoring and follow-up of patients using HC, helping to anticipate effective measures to mitigate TR.

References

Agence nationale de sécurité du medicament - ANSM. (2018). Sécurité du Médicament et des produits de Santé. ANSM. L’ANSM publie le rapport d’activité hémovigilance 2018. https://ansm.sante.fr/qui-sommes-nous/publications-institutionnelles/publications-2019.

Agência Nacional de Vigilância Sanitária - ANVISA. (2015). Marco Conceitual e Operacional de Hemovigilância: Guia para a Hemovigilância no Brasil. Brasília. https://www.gov.br/anvisa/pt-br/assuntos/fiscalizacao-e-monitoramento/hemovigilancia/publicacoes/marco-conceitual-e-operacional-de-hemovigilancia-guia-para-a-hemovigilancia-no-brasil.pdf/view

Allard, S., Cort, J., Howell, C., Sherliker, L., Miflin, G., & Toh, C. H. (2021). Transfusion 2024: A 5‐year plan for clinical and laboratory transfusion in England. Transfusion Medicine.

Alotaibi, Y. K., & Federico, F. (2017). The impact of health information technology on patient safety. Saudi Medical Journal, 38(12), 1173–1180. https://doi.org/10.15537/smj.2017.12.20631.

ANZSBT (2019). Guidelines for the administration of blood products. Australian & New Zealand Society of Blood Transfusion Ltd. 3 Ed. https://anzsbt.org.au/wp-content/uploads/2018/06/ANZSBT_Guidelines_Administration_Blood_Products_3rdEd_Jan_2018.pdf>.

Bernasinski, M., Gette, S., Malinovsky, J. M., Babel, F. V., Charpentier, C., Audibert, G., ... & Mertes, P. M. (2013). Les TRALI au CHU de Nancy: une incidence reconsidérée après l’application stricte des critères de Toronto. Transfusion clinique et biologique, 20(1), 40-45.

Bolcato, M., Russo, M., Trentino, K., Isbister, J., Rodriguez, D., & Aprile, A. (2020). Patient blood management: The best approach to transfusion medicine risk management. Transfusion and Apheresis Science, 59(4), 102779.

Brasil- Ministério da Saúde (2014). Documento de referência para o Programa Nacional de Segurança do Paciente.https://bvsms.saude.gov.br/bvs/publicacoes/documento_referencia_programa_nacional_seguranca.pdf

Cagliano, A. C., Grimaldi, S., & Rafele, C. (2021). A structured approach to analyse logistics risks in the blood transfusion process. Journal of Healthcare Risk Management.

Canadian Blood Services - CBS. (2017). System Progress Reports. https://www.blood.ca/en/about-us/publications-and-reports/system-progress-reports.

Center for Disease Control/National Healthcare Safety Network - CDC/NHSN. (2021). National Healthcare Safety Network biovigilance component hemovigilance module surveillance Protocol v2.6. The United States of America. https://www.cdc.gov/nhsn/pdfs/biovigilance/bv-hv-protocol-current.pdf.

Center for Disease Control/National Healthcare Safety Network - CDC/NHSN. (2018). NHSN Biovigilance Component, Hemovigilance Module Protocol. The United States of America. https://www.cdc.gov/nhsn/acute-care-hospital/bio-hemo/index.html.

Chasse, M., McIntyre, L., Tinmouth, A., Acker, J., English, S. W., Knoll, G., & Fergusson, D. A. (2015). Clinical effects of blood donor characteristics in transfusion recipients: protocol of a framework to study the blood donor-recipient continuum. BMJ Open, 5(1), e007412–e007412. https://doi.org/10.1136/bmjopen-2014-007412.

Dalal, A. K., Schaffer, A., Gershanik, E. F., Papanna, R., Eibensteiner, K., Nolido, N. V., ... & Schnipper, J. L. (2018). The impact of automated notification on follow-up of actionable tests pending at discharge: a cluster-randomized controlled trial. Journal of general internal medicine, 33(7), 1043-1051.

De Alcântara Oliveira, S., & Favaretto, F. (2021). Qualidade da Informação do Prontuário Eletrônico do Paciente no Processo de Apoio à Decisão Clínica. Journal of Health Informatics, 13(1).

Distler, P., & Ashford, P. (2019). Twenty‐five years later: has ISBT 128 fulfilled its promise? Transfusion, 59(12), 3776-3782.

Farokhzadian, J., Khajouei, R., Hasman, A., & Ahmadian, L. (2020). Nurses’ experiences and viewpoints about the benefits of adopting information technology in health care: a qualitative study in Iran. BMC Medical Informatics and Decision Making, 20(1), 1-12.

Forest, S. K., Shirazi, M., Wu-Gall, C., & Stotler, B. A. (2017). The impact of an electronic ordering system on blood bank specimen rejection rates. American journal of clinical pathology, 147(1), 105-109.

Garcia, J. (2020). Segurança do processo transfusional em pacientes cirúrgicos de um hospital público de ensino do interior de Minas Gerais. Dissertação do Programa de Pós-Graduação em Medicina Tropical e Infectologia. Minas Gerais: Universidade Federal do Triângulo Mineiro.

Gehrie, E. A., Savani, B. N., & Booth, G. S. (2021). Risk factors for hemolytic transfusion reactions resulting from ABO and minor red cell antigen incompatibility: From mislabeled samples to stem cell transplant and sickle cell disease. Blood reviews, 45, 100719.

Georgiou, A., Li, J., Hardie, R. A., Wabe, N., Horvath, A. R., Post, J. J., Eigenstetter, A., Lindeman, R., Lam, Q., Badrick, T., & Pearce, C. (2021). Diagnostic Informatics-The Role of Digital Health in Diagnostic Stewardship and the Achievement of Excellence, Safety, and Value. Frontiers in digital health, 3, 659652.

Georgiou, A., Li, J., Thomas, J., Dahm, M. R., & Westbrook, J. I. (2019). The impact of health information technology on the management and follow-up of test results - a systematic review. Journal of the American Medical Informatics Association: JAMIA, 26(7), 678–688.

Gonçalves, L. A. L., Pinto, A. C. S. (2018). Hemovigilância - investigação de subnotificação de reação transfusional imediata. Dissertação do Programa de Mestrado em Ciências.

Grant, A. M., Wright, F. A., & O'Brien, T. A. (2021). Rationalised premedication practice for blood product transfusions: A single‐centre quality initiative. Journal of paediatrics and child health.

Hasan, M., Siddiqui, I. A., Qamar, Z., & Hayat, A. (2021). An audit of transfusion reaction monitoring and reporting at a cancer hospital in Pakistan-a step towards hemovigilance. Journal of the Pakistan Medical Association, 71(2), 699-703.

Instituto Português do Sangue e da Transplantação - IPST. (2016). Base de dados do Instituto Português do Sangue e da Transplantação. https://www.ine.pt/xportal/xmain?xpid=INE&xpgid=ine_indicadores&indOcorrCod=0006132&contexto=bd&selTab=tab2

International Society of Blood Transfusion/International Haemovigilance Network, ISBT/IHN. (2019). Definição revisada de caso de vigilância internacional de sobrecarga circulatória associada à transfusão: uma classificação estudo de validação de contrato. https://www.isbtweb.org

Juffermans, N. P., Aubron, C., Duranteau, J., Vlaar, A. P., Kor, D. J., Muszynski, J. A., ... & Vincent, J. L. (2020). Transfusion in the mechanically ventilated patient. Intensive care medicine, 1-8.

Jug, R., Anani, W., & Callum, J. (2021). A possible case of recipient anti‐neutrophil and anti‐human leukocyte antigen antibody‐mediated fatal reverse transfusion‐related acute lung injury. Transfusion, 61(4), 1336-1340.

Karim, F., & Adil, S. N. (2017). Eliminating wrong blood transfusions-recent advances. Journal of Pakistan Medical Association, 67(5), 659-660.

Karim, F., Moiz, B., Shamsuddin, N., Naz, S., & Khurshid, M. (2014). Root cause analysis of non-infectious transfusion complications and the lessons learnt. Transfusion and Apheresis Science, 50(1), 111-117.

Kohorst, M. A., Khazal, S. J., Tewari, P., Petropoulos, D., Mescher, B., Wang, J., ... & Kelley, J. M. (2020). Transfusion reactions in pediatric and adolescent young adult haematology oncology and immune effector cell patients. EClinicalMedicine, 26, 100514.

Kracalik, I., Mowla, S., Basavaraju, S. V., & Sapiano, M. R. (2021). Transfusion‐related adverse reactions: Data from the National Healthcare Safety Network Hemovigilance Module—United States, 2013–2018. Transfusion, 61(5), 1424-1434.

Laudon, K. C., Laudon, J. P., & Marques, A. S. (2014). Sistemas de informação gerenciai. Pearson Educación.

Lee, J., & Maslove, D. M. (2015). Using information theory to identify redundancy in common laboratory tests in the intensive care unit. BMC medical informatics and decision making, 15(1), 1-8.

Lee, T. Y., Sun, G. T., Kou, L. T., & Yeh, M. L. (2017). The use of information technology to enhance patient safety and nursing efficiency. Technology and health care : official journal of the European Society for Engineering and Medicine, 25(5), 917–928.

Miller, K., Akers, C., Magrin, G., Whitehead, S., & Davis, A. K. (2013). Piloting the use of 2D barcode and patient safety‐software in an Australian tertiary hospital setting. Vox Sanguinis, 105(2), 159-166.

Lemma, S., Janson, A., Persson, L. Å., Wickremasinghe, D., & Källestål, C. (2020). Improving quality and use of routine health information system data in low-and middle-income countries: A scoping review. PloS one, 15(10), e0239683.

Mai, S., Guimarães, C. F., Silva, J. M., & Hinkel, J. H. S. (2017). O uso das tecnologias na democratização da informação em saúde. Revista de Gestão em Sistemas de Saúde, 6(3), 210-218.

Marchesan Neto, R. (2018). Desenvolvimento de um protótipo de sistema informatizado de controle para gestão da saúde. Trabalho de conclusão de curso (TCC) em Ciências da Computação.

Maskens, C., Downie, H., Wendt, A., Lima, A., Merkley, L., Lin, Y., & Callum, J. (2014). Hospital‐based transfusion error tracking from 2005 to 2010: identifying the key errors threatening patient transfusion safety. Transfusion, 54(1), 66-73.

Massey, E. J., Davenport, R. D., & Kaufman, R. M. (2017). Haemolytic transfusion reactions. Practical Transfusion Medicine, 81-96.

Mueller, M. M., Van Remoortel, H., Meybohm, P., Aranko, K., Aubron, C., Burger, R., ... & Seifried, E. (2019). Patient blood management: recommendations from the 2018 Frankfurt Consensus Conference. Jama, 321(10), 983-997.

Mueller, T. (2020). Information technology and eHealth to improve patient safety. Der Internist.

Nicanor, J. S. (2017). Desenvolvimento e aplicação de um programa computacional para armazenamento de dados e seguimento de pacientes em hemoterapia. Dissertação do Programa de Mestrado em Hemoterapia. São Paulo: Universidade de São Paulo.

Ohno-Machado, L. (2017). Using health information technology for clinical decision support and predictive analytics. Journal of the American Medical Informatics Association, 24(1), 1-1.

Ohsaka, A., Kato, H., Kino, S., Kawabata, K., Kitazawa, J., Sugimoto, T., ... & Handa, M. (2016). Recommendations for the electronic pre-transfusion check at the bedside. Blood Transfusion, 14(5), 419.

Omizzolo, J. E., & Ramos, K. S. (2021). Registros de enfermagem: um instrumento para a qualidade da assistência. Inova Saúde, 11(1), 114-129.

Orfão, N. H., Crepaldi, N. Y., Brunello, M. E. F., Andrade, R. L. D. P., Monroe, A. A., Ruffino-Netto, A., & Villa, T. C. S. (2017). Coordenação da assistência à tuberculose: registro de dados e a implementação de um sistema informatizado. Ciência & Saúde Coletiva, 22, 1969-1977.

Paranhos, L. R. L.; Paranhos, P. J. R. (2018). Metodologia da pesquisa aplicada à tecnologia. SENAI-SP Editora.

Pressman, R. S. (2009). Engenharia de Software. 7 ed.,Amgh Editora.

Pressman, R. S.; Maxim, B. R. (2020). Software engineering: a practitioner’s approach. 9 ed ed. United States of America: McGraw-Hill Education.

Ramoa, A., Condeço, J., Escoval, M. A., Faber, J. C., Fdez-Riverola, F., & Lourenço, A. (2018). The Evolving Role of Information Technology in Haemovigilance Systems. Journal of healthcare engineering.

Santos, M. C. D., & Marin, H. D. F. (2018). Análise do uso de um sistema informatizado por gestores hospitalares. Acta Paulista de Enfermagem, 31, 1-6.

Sawadogo, S., Nebie, K., Millogo, T., Sontie, S., Nana, A., Dahourou, H., ... & Deneys, V. (2018). Traceability of blood transfusions and reporting of adverse reactions in developing countries: a six-year postpilot phase experience in Burkina Faso. Advances in hematology, 2018.

Šendelj R. (2020). Information Technology and Information Management in Healthcare. Studies in health technology and informatics, 274, 139–158.

Silva, A. B., de Oliveira, A. A., Silva, J. D. O. M., Santos, G. K. D. B. B., Esteves, R. B., & da Silva, Â. M. (2021a). Caracterização epidemiológica das reações transfusionais imediatas em um hospital público de ensino. Research, Society and Development, 10(9), e5110916635-e5110916635.

Silva, A. B., Oliveira, A. A. de, Silva, J. de O. M., Santos , G. K. de B. B. ., Esteves, R. B., & Silva, Ângela M. da . (2021b). Proposal of a standard operating procedure for the mitigation of immediate transfusion reactions in a university hospital. Research, Society and Development, 10(11), e32101119257. https://doi.org/10.33448/rsd-v10i11.19257

Soares, F. M. M., Cruz, R. C., Almeida, R. D., da Silva Camilo, J. K., & Scopacasa, L. F. (2019). Avaliação Dos Registros De Enfermagem Acerca Da Reação Transfusional. Revista Enfermagem Atual In Derme, 90(28).

Staples, S., Staves, J., Davies, J., Polley, N., Boyd, J. S., Lukas, M., ... & Murphy, M. F. (2019). Electronic remote blood issue supports efficient and timely supply of blood and cost reduction: evidence from five hospitals at different stages of implementation. Transfusion, 59(5), 1683-1691.

Tamfon, B. B., Bilounga Ndongo, C., Bataliack, S. M., Ngoufack, M. N., & Nguefack-Tsague, G. (2020). Routine health information system in the health facilities in Yaoundé–Cameroon: assessing the gaps for strengthening. BMC Medical Informatics and Decision Making, 20(1), 1-11.

Tsang, H. C., Garcia, A., Scott, R., Lancaster, D., Geary, D., Nguyen, A. T., ... & Pham, T. D. (2018). Streamlining a blood center and hospital transfusion service supply chain with an informatics vendor‐managed inventory solution: development, implementation, and 3‐month follow‐up. Transfusion, 58(7), 1718-1725.

Vasudev, R., Sawhney, V., Dogra, M., & Raina, T. R. (2016). Transfusion-related adverse reactions: From institutional hemovigilance effort to National Hemovigilance program. Asian journal of transfusion science, 10(1), 31.

Wazlawick, R. (2019). Engenharia de software: conceitos e práticas. Elsevier Editora Ltda.

Webert, K. E., & Heddle, N. M. (2017). Investigation of Acute Transfusion Reactions. Practical Transfusion Medicine, 69-80.

Williams, F., Oke, A., & Zachary, I. (2019). Public health delivery in the information age: the role of informatics and technology. Perspectives in public health, 139(5), 236-254.

Published

19/02/2022

How to Cite

SILVA, A. B. .; SILVA, J. de O. M.; LIMA, V. N. B.; SILVA, G. C. da; TELES, I. L. D. .; MARTINS JÚNIOR, J. A. L.; SANTOS NETO, A. J. dos .; SILVA, Ângela M. da .; OLIVEIRA, A. A. de . Development of the Hemomonitor with an alert system for the patient using blood componentes. Research, Society and Development, [S. l.], v. 11, n. 3, p. e20911326300, 2022. DOI: 10.33448/rsd-v11i3.26300. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/26300. Acesso em: 25 nov. 2024.

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Section

Health Sciences