Surgical treatment of odontogenic keratocyst associated with cryotherapy with refrigerant gas: 10-year follow-up

Authors

DOI:

https://doi.org/10.33448/rsd-v11i3.26784

Keywords:

Bone cysts; Cryotherapy; Conservative treatment.

Abstract

Odontogenic keratocyst (OKC) is an intraosseous cystic lesion, being one of the most common cysts of the gnathic bones, responsible for 3% to 11% of all odontogenic cysts. This cyst has high recurrence rates, from 5 to 62%, and usually occurs within the first 5 years, and may be directly linked to the type of technique used to treat the lesion. The forms of treatment for OKC may vary according to its clinical and imaging presentation. Considering the high recurrence rates of this benign pathology, only enucleation may not be enough, so other forms of adjuvant treatment are proposed, such as cryotherapy. This case report aims to present the case of a 22-year-old female patient who presented an odontogenic keratocyst (OKC) in the right mandible diagnosed in 2012. Surgical treatment of enucleation and adjuvant treatment with cryotherapy using refrigerant gas were performed. The patient has been followed up for 10 years, without complaints and has not had any recurrence of the cyst.

References

Al-Moraissi, E. A., Dahan, A. A., Alwadeai, M. S., Oginni, F. O., Al-Jamali, J. M., Alkhutari, A. S., & Al-Sanabani, J. S. (2017). What surgical treatment has the lowest recurrence rate following the management of keratocystic odontogenic tumor?: A large systematic review and meta-analysis. Journal of Cranio-Maxillofacial Surgery. 45(1), 131-144.

Bansal, A., Jain, S., & Gupta, S. (2012). Cryosurgery in the treatment of oro-facial lesions. Indian Journal of Dental Research. 23(2), 297-302.

Barbosa, J. F., & Sanvitto, L. C. (1973). Crioterapia local (Criocirurgia)–denominação e histórico. Boletim de Oncologia. 3(3-4), 29-34.

Barnes, L., Eveson, J. W., Sidransky, D., & Reichart, P. (Eds.). (2005). Pathology and genetics of head and neck tumours. Vol. 9. IARC Press.

Benaglia, M. B. (2014). Estudo morfológico comparativo da crioterapia com nitrogênio líquido e gás refrigerante propano-butano na mucosa bucal de ratos. (dissertação de mestrado, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS). https://repositorio.ufms.br/browse?type=subject&value=Nitrogen

Benaglia, M. B., Jardim, E. C. G., & Mendonca, J. C. (2014). Criocirurgia em odontologia: vantagens e desvantagens. Brazilian Journal of Surgery and Clinical Research. 7(3), 58-67.

Castro, M. S., Caixeta, C. A., de Carli, M. L., Ribeiro Junior, N. V., Miyazawa, M., Pereira, A. A. C., ... & Hanemann, J. A. C. (2018). Conservative surgical treatments for nonsyndromic odontogenic keratocysts: a systematic review and meta-analysis. Clinical Oral Investigations. 22(5), 2089-2101.

Chrcanovic, B. R., & Gomez, R. S. (2017). Recurrence probability for keratocystic odontogenic tumors: an analysis of 6427 cases. Journal of cranio-Maxillofacial Surgery. 45(2), 244-251.

Costa, F. W. G., Soares, E. C. S., & Batista, S. H. B. (2010). Criocirurgia no tratamento de lesões benignas dos maxilares: revisão de literatura e análise de 103 casos previamente reportados. RSBO Revista Sul-Brasileira de Odontologia. 7(2), 208-215.

Slusarenko da Silva, Y., Stoelinga, P. J., & Naclério-Homem, M. D. G. (2019). Recurrence of nonsyndromic odontogenic keratocyst after marsupialization and delayed enucleation vs. enucleation alone: a systematic review and meta-analysis. Oral and Maxillofacial Surgery. 23(1), 1-11.

Slusarenko da Silva, Y., Stoelinga, P. J., & Naclério-Homem, M. D. G. (2019). The presentation of odontogenic keratocysts in the jaws with an emphasis on the tooth-bearing area: a systematic review and meta-analysis. Oral and Maxillofacial Surgery. 23(2), 133-147.

Oliveira, M. H., de Oliveira Aguillera, M., dos Santos, M. E. S., Figueiredo, F. T., Nejaim, Y., Antunes, D. M., & Jardim, E. C. G. (2021). Queratocisto odontogênico: índice de recorrência em função do tipo de tratamento. Archives Of Health Investigation. 10(9), 1396-1402.

Díaz-Belenguer, Á., Sánchez-Torres, A., & Gay-Escoda, C. (2016). Role of Carnoy’s solution in the treatment of keratocystic odontogenic tumor: a systematic review. Medicina Oral, Patologia Oral Y Cirugia Bucal. 21(6), 689-695.

Santos, A. O. G. M., de Mendonça, J. C. G., Pelissaro, G. S., Paiva-Oliveira, J. G., da Silva, J. C. L., de Oliveira Aguillera, M., & Jardim, E. C. G. (2021). Curetagem cirúrgica associada à crioterapia como alternativa para tratamento de mixoma odontogênico em maxila: Relato de um caso clínico. Research, Society and Development. 10(10), e103101018693-e103101018693.

Fonseca, E. V., Franzi, S. A., Marcucci, M., & De Almeida, R. C. (2010) Clinical, histopathological and treatment factor of the odontogenic keratocyst. Brazilian Journal of Head and Neck Surgery. 39(1), 57-61.

Gage, A. A., Baust, J. M., & Baust, J. G. (2009). Experimental cryosurgery investigations in vivo. Cryobiology. 59(3), 229-243.

Gaitán‐Cepeda, L. A., Quezada‐Rivera, D., Tenorio‐Rocha, F., & Leyva‐Huerta, E. R. (2010). Reclassification of odontogenic keratocyst as tumour. Impact on the odontogenic tumours prevalence. Oral Diseases. 16(2), 185-187.

Ghali, G. E., & Connor, M. S. (2003). Surgical management of the odontogenic keratocyst. Oral and Maxillofacial Surgery Clinics. 15(3), 383-392.

Gupta, A., Bansal, P., Sharma, R., & Sharma, S. D. (2016). Treatment of keratocystic odontogenic tumours: a prospective study of 30 cases. Journal of Maxillofacial and Oral Surgery, 15(4), 521-527.

Kaczmarzyk, T., Mojsa, I., & Stypulkowska, J. (2012). A systematic review of the recurrence rate for keratocystic odontogenic tumour in relation to treatment modalities. International Journal of Oral and Maxillofacial Surgery. 41(6), 756-767.

Karaca, Ç., Dere, K. A., Er, N., Aktaş, A., Tosun, E., Köseoğlu, O. T., & Usubütün, A. (2018). Recurrence rate of odontogenic keratocyst treated by enucleation and peripheral ostectomy: Retrospective case series with up to 12 years of follow-up. Medicina Oral, Patología Oral Y Cirugía Bucal. 23(4), e443.

Kinard, B. E., Chuang, S. K., August, M., & Dodson, T. B. (2013). How well do we manage the odontogenic keratocyst?. Journal of Oral and Maxillofacial Surgery. 71(8), 1353-1358.

Leopard, P. J. (1975). Cryosurgery, and its application to oral surgery. The British Journal of Oral Surgery. 13(2), 128-152.

Mendonça, J. C. G., Santos, A. A., & Lopes, H. B. (2011). Hemimaxilectomia associada à crioterapia no tratamento de ameloblastoma: relato de caso. Revista Brasileira de Cirurgia Craniomaxilofacial. 14(1), 63-6.

Morgan, T. A., Burton, C. C., & Qian, F. (2005). A retrospective review of treatment of the odontogenic keratocyst. Journal of Oral and Maxillofacial Surgery. 63(5), 635-639.

Moura-Netto, C., Yamazaki, A. K., Cardoso, L. N., Cabrales, R. J. S., & Prokopowitsch, I. (2007). Avaliação da temperatura mínima alcançada por cinco gases refrigerantes Lowest temperature reached by five cold spray gases. Revista do Instituto de Ciências da Saúde. 25(4), 403-5.

Neville, B. W., Damm, D. D., Allen, C. M., & Bouquot, J. E. (2009) Patologia Oral e Maxilofacial. Elsevier.

Osterne, R. L. V., de Matos Brito, R. G., Alves, A. P. N. N., Cavalcante, R. B., & Sousa, F. B. (2011). Odontogenic tumors: a 5-year retrospective study in a Brazilian population and analysis of 3406 cases reported in the literature. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology. 111(4), 474-481.

Pitak-Arnnop, P., Chaine, A., Oprean, N., Dhanuthai, K., Bertrand, J. C., & Bertolus, C. (2010). Management of odontogenic keratocysts of the jaws: a ten-year experience with 120 consecutive lesions. Journal of Cranio-Maxillofacial Surgery. 38(5), 358-364.

Ribeiro-Júnior, O., Borba, A. M., Alves, C. A. F., Gouveia, M. M. D., Deboni, M. C. Z., & Naclério-Homem, M. D. G. (2017). Reclassification and treatment of odontogenic keratocysts: A cohort study. Brazilian Oral Research. 31.

Schmidt, B. L. (2003). The use of liquid nitrogen cryotherapy in the management of the odontogenic keratocyst. Oral and Maxillofacial Surgery Clinics. 15(3), 393-405.

Sharif, F. N., Oliver, R., Sweet, C., & Sharif, M. O. (2015). Interventions for the treatment of keratocystic odontogenic tumours. Cochrane database of systematic reviews. 11.

Shear, M., & Speight, P. (2008). Cysts of the oral and maxillofacial regions. John Wiley & Sons.

Sigua-Rodriguez, E. A., Goulart, D. R., Sverzut, A., Asprino, L., & de Moraes, M. (2019). Is surgical treatment based on a 1-step or 2-step protocol effective in managing the odontogenic keratocyst?. Journal of Oral and Maxillofacial Surgery. 77(6), 1210-e1.

Stoelinga, P. J. (2005). The treatment of odontogenic keratocysts by excision of the overlying, attached mucosa, enucleation, and treatment of the bony defect with carnoy solution. Journal of Oral and Maxillofacial Surgery. 63(11), 1662-1666.

Tal, H. (1982). The rationale and technique of cryotherapy of superficial oral lesions. The Journal of the Dental Association of South Africa. 37(5), 335-340.

Published

01/03/2022

How to Cite

MENDONÇA, J. C. G. de; JARDIM, E. C. G. .; SILVA, J. C. L. da; VALENTE, F. R. F. .; SANTOS, M. E. S. dos . Surgical treatment of odontogenic keratocyst associated with cryotherapy with refrigerant gas: 10-year follow-up. Research, Society and Development, [S. l.], v. 11, n. 3, p. e40511326784, 2022. DOI: 10.33448/rsd-v11i3.26784. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/26784. Acesso em: 16 apr. 2024.

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Section

Health Sciences