Ozone therapy as an adjuvant method in endodontic treatment: an integrative review
DOI:
https://doi.org/10.33448/rsd-v11i4.27215Keywords:
Ozone; Dentistry; Oral Cavity; Endodontics.Abstract
Ozone therapy is an adjuvant and optional therapeutic treatment with ozone administration. In dentistry it is promising for its biological attributes such as antimicrobial effect, analgesia, anti-inflammatory property and tissue resting. The objective of this work was to carry out an integrative review of the use of ozone as an auxiliary therapy in endodontic treatment. Searches for articles were performed in the following databases: Scielo and Pubmed. Inclusion criteria published between 2016 to 2021, with online access, were considered. The search keys used were: Ozone and root canal and endodontic and Ozone and root canal. 88 articles were found in the selected databases, after screening by title and abstract 26 studies were selected, among the 26 articles, 17 of them were selected for full reading, 11 articles were excluded for not being available for full reading in PDF and 6 studies were included for this integrative review. The ways of using ozone in the present study were ozonized water and ozone gas. The use of ozone has positive results, in most studies in both forms, when compared to the use only of conventional irrigants.
References
Ajeti, N. N., Pustina, K. T., & Apostolska S. (2018). The Effect of Gaseous Ozone in Infected Root Canal. Open Access Maced J Med Sci; 14;6(2):389-396.
Azarpazhooh, A,, Limeback, H., Lawrence H. P., & Fillery E. D., (2008). Evaluatingthe effect fan ozone delivery system on there versal of dentin hypersensitivity: a randomized, double blinde clinical trial. J Endod. 35:1-9.
Beretta, M., & Federici, C. F., (2017). A new method for deep caries treatment in primary teeth using ozone: A retrospective study. Europe an Journal of Paediatric Dentistry. 2(18):111–115.
Bitter, K., Vlassakidis, A., Niepel, M., Hoedke, D., Schulze, J., Neumann, K., Moter, A., & Noetzel, J. (2017). Effects of Diode Laser, Gaseous Ozone, and Medical Dressings on Enterococcus faecalis Biofilms in the Root Canal Ex Vivo. Biomed Res Int.;2017:6321850.
Das, S. (2011). Application of ozone therapy in dentistry. Indian J Dent Adv. 3:538–542.
Doğan, M., Ozdemir, D. D,, Düger, C., Ozdemir, K., Akpinar, A., Mutaf, B., & Akar, T. (2014). Effects of high frequency bio-oxidative ozone therapy in temporomandibular disorder related pain. Med Princ Pract. 23(6):507-10.
Endo, M. S., Ferraz, C. C., Zaia, A. A., Almeida, J. F., & Gomes, B. P. (2013). Quantitative and qualitative analysis of microorganisms in root filled teeth with persistent infection: monitoring of the endodontic retreatment. Eur J Dent. 7(3):302-9.
Filippi, A. (2001). The effects of ozone zed water on epithelial wound healing (in German). Deutsche Zahna¨rztliche Zeitschrift. 56:104-8.
Halbauer, K., Prskalo, K., Jankovic, .B, Tarle, Z. ,Panduric, V., & Kalenic, S. (2013). Efficacy Of Ozone On Microorganisms In The Tooth Root Canal. Coll Antropol. 37:101-107.
Hyslop, P., A., Hinshaw, D., B., Halsey, W. A. (1988). Mechanisms of oxidant-mediated cell injury. The glycolytic and mitochondrial pathways of ADP phosphorylation are major intracellular targets inactivated by hydrogen peroxide. The Journal of Biological Chemistry. 263:1665-1675.
Kazancioglu, H. O., & Erisen, M., (2015). Comparisono flow-level laser therapy versus ozone therapy in the treatment of oral lichenplanus. Ann Dermatol. 27:485-491.
Kist, S., Kollmuss, M., Jung, J., Schubert, S., Hickel, R., & Huth, K. C. (2017). Comparison of ozone gas and sodium hypochlorite/chlorhexidine two-visit disinfection protocols in treating apical periodontitis: a randomized controlled clinical trial. Clin Oral Investig. May;21(4):995-1005.
Mehta, N., Gupta , A., Mahesh, S., Abraham, D., Singh, A., Jala, S., Chauhan, N., & Sreen, D. (2020). Comparative evaluation of antibacterial efficacy of Allium sativum extract, aqueous ozone, diode laser, and 3% sodium hypochlorite in root canal disinfection: An in vivo study. J Conserv Dent. Nov-Dec;23(6):577-582.
Moraes, M. M, Coelho, M. S., Nascimento, W. M., Nogales, C, G., de Campos, F. U., de Jesus Soares, A., & Frozoni, M. (2021). The antimicrobial effect of different ozone protocols applied in severe curved canals contaminated with Enterococcus faecalis: ex vivo study. Odontology. Jul;109(3):696-700.
Neelakantan, P., Herrera, D. R.,Pecorari, V. G. A., & Gomes, B. (2019). Endotox in level safter chemome chanical preparation of root canals withs odium hypochlorite orchlor hexidine: a systematic review of clinical trials and meta-analysis. International Endodontic Journal. 52:19-27.
Nogales C. G., Ferreira, M. B., Montemor, A. F., Rodrigues, M. F., & Marques, J. L., Antoniazzi, J. (2016). Ozone therapy as an adjuvant for endondontic protocols: microbiological – ex vivo study and citotoxicityanalyses. Original articles j. Appl. Oral sci. Nov-dec:24 (6).
Ripamonti, C. I., Maniezzo, M., Pessi, M. A., & Boldini, S., Treatment of osteonecrosis of the jaw (ONJ) by medical ozone gasinsufflation.(2012). A case report. Tumori. 98:72-75.
Santos, M. G. et al. (2017). Análise do uso da terapia fotodinâmica no tratamento endodôntico com base em um Congresso Odontológico. RFO, 1(22):49-53.
Silva, E. J., Carvalho, C. R, Belladonna, F. G., Prado, M. C., Lopes, R. T,, Deus, G. et al. (2019). Micro CT evaluation of different final irrigation protocols on there moval of hard tissue debris from is the muscontaining mesial root of mandibular molars. Clinical Oral Investigations. 23:681-7.
Siqueira, J. J. F., Rocas, I. D.N .,Marceliano, A. M. F., Perez, A. R., & Ricucci, D. (2018). Unprepared root canal surfaceareas: causes, clinical implications, and therapeutics trategies. Brazilian Oral Research. 32:65.
Sivieri, A. G, et al. (2013). Terapia fotodinâmica na endodontia: uma estratégia coadjuvante no combate à infecção endodôntica. 2 (33º Jornada Acadêmica “Prof.Dr.Edmur Aparecido Callestini”), 3.º Congresso da Faculdade de Odontologia de Araçatuba. Araçatuba, São Paulo, Brasil: Unesp - Campus de Araçatuba.
Slaughter, R. J., Watts, M., Vale, J. A., Grieve, J. R., & Schep, L.J. (2019).The clinical toxicology of sodium hypochlorite. Clinical Toxicology (Philadelphia, Pa.). 57:303-11.
Srinivasan, K., & Chitra, S. (2015). The Application of Ozone in Dentistry: A Systematic Review of Literature. Scholars Journal of Dental Sciences. 2(6):373-377.
Subiksha, P. S.(2016). Ozone and its uses in root canal therapy-areview. J PharmSci Res. 8:1073.
Suh, Y., Patel, S., Kaitlyn, R., Gandhi, J., Joshi, G.,Mith, N. L., & Khan ,S. A. (2019). Clinical utility of ozone therapy in dental and oral medicine. Med Gas Res. 9(3):163-167.
Taşdemir, Z., Alkan, B.A., & Albayrak, H. (2016). Effectsof Ozone Therapy on the Early Healing Period of Deepithelialized Gingival Grafts. A Randomized Placebo Controlled Clinical Trial. J Periodontol.87(6):663-71.
Tessier, J., Rodriguez, P. N.,Lifshitz , F., Friedman, S. M., & Lana, E. J. (2010). The use of ozone to light en teeth: An experimental study. Acta Odonto lLatinoam. 23:84-89.
Whittemore, R., & Knafl, K. (2005). The integrative review: up date methodology. J AdvNurs. 52(5):546-53.
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Copyright (c) 2022 Alynne Correia de Andrade; Myllenna Nayara de França Alves; Maria Eduarda de Araujo Cruz; Niebla Bezerra de Melo; Fernanda Clotilde Mariz Suassuna; Luiza de Almeida Souto Montenegro; Amanda Lira Rufino de Lucena; Herrison Félix Valerino da Silva; Jussara da Silva Barbosa
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