Diagnosis and management of xerostomia in patients with COVID-19

Authors

DOI:

https://doi.org/10.33448/rsd-v11i5.27894

Keywords:

Oral manifestations; Xerostomia; COVID-19.

Abstract

Xerostomia or dry mouth is a change found routinely in clinical dental practice, this change directly affects the patient's quality of life, manifesting difficulties in tasting, chewing, speaking, swallowing and causing a lot of discomfort in the oral cavity. However, after the onset of the COVID-19 pandemic, researchers noticed a large complaint of infected patients reporting the sensation of dry mouth. The main objective of this study is to evaluate the way that xerostomia affects patients with COVID-19. The study was carried out through a literature review, searching Google Scholar, PubMed, and SciELO articles using the descriptors: “Oral Manifestations”; “Xerostomia” and “COVID-19”. All articles were selected by year, title, abstract, full text and, finally, all selected articles were processed for final review. 20 selected articles were obtained from the initial bibliographic research of 295 articles, reports obtained from the selected studies demonstrate that xerostomia has a high incidence in patients who were infected by COVID-19, which directly impacts their quality of life and the way that they react to the treatments when they are submitted to hospital treatments, however, other oral manifestations appear strongly, which causes a greater debilitation in the patient's systemic health. Oral manifestations, such as xerostomia, taste problems, inflammation of the salivary glands, duly mentioned in the study, are typically reported in patients who had a viral infection by Sars-CoV-2, and it is worth noting that, regardless of the pathogenesis of these manifestations, the importance of developing specific protocols.

References

Fathi, Y., Hoseini, EG, Atoof, F., & Mottaghi, R. (2021). Xerostomia (boca seca) em pacientes com COVID-19: uma série de casos. Future Virology , 16 (5), 315-319.

Tuñas, I. T. d. C., Silva, E. T. d., Santiago, S. B. S., Maia, K. D., & Silva-Júnior, G. O. (2020). Coronavirus disease 2019 (COVID-19): One preventive approach to dentistry.

Furtado, G. S., de Siqueira Menezes, B. L., de Menezes, K. K. C., Feitosa, M. Á. L., Lima, D. M., & Casanovas, R. C. (2021). A infecção pela Covid-19 provoca manifestações bucais? Uma revisão de litertura. Research, Society and Development, 10(7), e0710716081-e0710716081.

de Sousa, F., & Paradella, T. C. (2021). Considerations on oral manifestations of COVID-19. Journal of medical virology, 93(2), 667–668.

Brandini, D. A., Takamiya, A. S., Thakkar, P., Schaller, S., Rahat, R., & Naqvi, A. R. (2021). Covid-19 and oral diseases: Crosstalk, synergy or association?. Reviews in medical virology, 31(6), e2226

Santos Júnior, J. C. C., de Souza, M. S., dos Santos, V. S., Carvalho, J. M. S., Pires, A. L. P. V., & Almeida, C. B. S. (2020). Lesões orais em pacientes com COVID-19: uma síntese de evidências atuais. Journal of Dentistry & Public Health (inactive/archive only), 11(2), 224-232.

Amorim, J. D. S., Normando, A. G. C., Carvalho da Silva, R. L., Acevedo, A. C., De Luca Canto, G., Sugaya, N., ... & Guerra, E. N. S. (2021). Oral manifestations in patients with COVID-19: a living systematic review. Journal of dental research, 100(2), 141-154.

Taques, L., Bortoluzzi, M. C., Karpinski, B. C., Brigola, S., de Mattos, J. C., & Rodachinski, P. (2020). Alterações do sistema estomatognático frente à COVID-19-uma revisão integrativa. Brazilian Journal of Health Review, 3(6), 18600-18615.

Tsuchiya, H. (2021). Characterization and Pathogenic Speculation of Xerostomia Associated with COVID-19: A Narrative Review. Dentistry Journal, 9(11), 130.

Fantozzi, P. J., Pampena, E., Di Vanna, D., Pellegrino, E., Corbi, D., Mammucari, S., ... & Villa, A. (2020). Xerostomia, gustatory and olfactory dysfunctions in patients with COVID-19. American journal of otolaryngology, 41(6), 102721.

Dos Santos, J. A., Normando, A. G. C., da Silva, R. L. C., De Paula, R. M., Cembranel, A. C., Santos-Silva, A. R., & Guerra, E. N. S. (2020). Oral mucosal lesions in a COVID-19 patient: New signs or secondary manifestations?. International Journal of Infectious Diseases, 97, 326-328.

Okada, Y., Yoshimura, K., Toya, S., & Tsuchimochi, M. (2021). Pathogenesis of taste impairment and salivary dysfunction in COVID-19 patients. Japanese Dental Science Review, 57, 111-122.

Xu, H., Zhong, L., Deng, J., Peng, J., Dan, H., Zeng, X., ... & Chen, Q. (2020). High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa. International journal of oral science, 12(1), 1-5.

Chen, L., Zhao, J., Peng, J., Li, X., Deng, X., Geng, Z., ... & Wang, S. (2020). Detection of SARS‐CoV‐2 in saliva and characterization of oral symptoms in COVID‐19 patients. Cell proliferation, 53(12), e12923.

Baeder, F. M. ., Albuquerque, A. C. L. de, Corazza, P. F. L. ., Weigert, K. . L., Puricelli, E., Pasetti, L. A., Ferreira, A. M., Serrão, M. do C. P. N. ., Cardoso, A. M. R. ., Brito Filho, M. T. de ., Teodósio, G. C., Bomfim, M. A. C., Sobrinho, A. C. P. ., Forghieri, A. A., & Silva, D. F. . (2021). Oral lesions in patients infected with SARS-CoV-2: a case series . Research, Society and Development, 10(4), e45410414349.

Rodríguez, M. D., Jimenez Romera, A., & Villarroel, M. (2020). Oral manifestations associated with COVID-19. Oral diseases, 10.1111/odi.13555. Advance online publication. https://doi.org/10.1111/odi.13555

Biadsee, A., Biadsee, A., Kassem, F., Dagan, O., Masarwa, S., & Ormianer, Z. (2020). Olfactory and Oral Manifestations of COVID-19: Sex-Related Symptoms-A Potential Pathway to Early Diagnosis. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 163(4), 722–728.

Omezli, M. M., & Torul, D. (2021). Evaluation of the xerostomia, taste and smell impairments after Covid-19. Medicina oral, patologia oral y cirugia bucal, 26(5), e568–e575.

Sinjari, B., D'Ardes, D., Santilli, M., Rexhepi, I., D'Addazio, G., Di Carlo, P., Chiacchiaretta, P., Caputi, S., & Cipollone, F. (2020). SARS-CoV-2 and Oral Manifestation: An Observational, Human Study. Journal of clinical medicine, 9(10), 3218

Capocasale, G., Nocini, R., Faccioni, P., Donadello, D., Bertossi, D., Albanese, M., & Zotti, F. (2021). How to deal with coronavirus disease 2019: A comprehensive narrative review about oral involvement of the disease. Clinical and experimental dental research, 7(1), 101–108.

Published

31/03/2022

How to Cite

FERREIRA, G. L. C.; GOMES, A. V. S. F. .; SOUSA, A. C. C. .; LOPES, E. M. .; VIEGAS, R. de O. .; FRANÇA, A. A. M. D. S. da .; CASTRO, F. Ângela S. .; CARVALHO, R. de A. .; FONTENELE , M. Éryka G. de B. .; FORTALEZA, V. G. . Diagnosis and management of xerostomia in patients with COVID-19. Research, Society and Development, [S. l.], v. 11, n. 5, p. e13111527894, 2022. DOI: 10.33448/rsd-v11i5.27894. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/27894. Acesso em: 21 nov. 2024.

Issue

Section

Health Sciences