Comparison between four hours and twenty-four hours endogenous creatinine clearances and exogenous creatinine in healthy dogs




Chronic kidney disease; Function tests; Canine.


The chronic kidney disease is the main cause of kidney illness in dogs. The evaluation of glomerular filtration rate (GFR) is essential for the diagnosis of this disease, using endogenous or exogenous creatinine clearance tests. Two methods of evaluation can be found in Brazil, the dual twenty minutes, and the twenty-four hours one. Ten healthy (verified with hematological, urinalysis, biochemical and physical evaluation) animals with ages between one and eight years and weight around twelve kilograms from the kennel of veterinary hospital of Universidade de Franca was submitted to three kinds of GFR tests (twenty-four hours endogenous creatinine clearance, clearance of exogenous creatinine and four hour endogenous creatinine clearance). Significant difference was found between the results of the methods, indicating that the four-hour endogenous creatinine clearance has potential to be utilized in the veterinarian routine.


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How to Cite

SILVA, A. C. .; STANTE, F. H. R. .; BRUM, A. M. de .; PAULINO JUNIOR, D. . Comparison between four hours and twenty-four hours endogenous creatinine clearances and exogenous creatinine in healthy dogs. Research, Society and Development, [S. l.], v. 11, n. 6, p. e18311628899, 2022. DOI: 10.33448/rsd-v11i6.28899. Disponível em: Acesso em: 14 jun. 2024.



Agrarian and Biological Sciences