Integrative review: do antihypertensive drugs have additional effects on post-exercise hypotension (PEH)?
DOI:
https://doi.org/10.33448/rsd-v11i6.29287Keywords:
Physical exercise; Antihypertensives; Hypotension.Abstract
Lifestyle and eating habits are factors that influence the quality of life of individuals and when these variables occur in a negative way, such as excessive use of alcohol and processed foods, they become factors that contribute to the emergence of Chronic Noncommunicable Diseases (CNCD), such as Arterial Hypertension (AH). Treatment can occur with the insertion of antihypertensive drugs (pharmacological route) and physical exercise (non-pharmacological route). However, there are gaps regarding investigations between the combination of these two therapies. The study aims to analyze through an integrative review whether the hypotensive effect of physical exercise is potentiated by the use of antihypertensive drugs. Method: integrative review, with research carried out in the journals: GOOGLE ACADÉMICO, MEDLINE, PUBMED, SCIELO AND LILACS, with the descriptors in Portuguese and English of the words: physical exercise, antihypertensive, hypotension. Results: The final sample consisted of 7 articles selected after the inclusion and exclusion criteria. Conclusion: The use of Angiotensin Receptor Blockers (ARB), IECA, Diuretics (thiazide and potassium sparing) and Calcium Channel Blockers (CCB) can potentiate the hypotensive effect of physical exercise. However, the number of studies on this topic is limited, which requires more robust experimental designs.
References
Almeida, L. M., Vieira, C. F, Fernandes, E. T, Silva, G. T.G, Rinaldi, M. L, Pereira, R. B, Antonil, T, Fontes, L. B. A. (2017). Diuréticos: um artigo de revisão. Revista científica fagoc (2). https://revista.unifagoc.edu.br/index.php/saude/article/view/188/233
Barroso, W. K. S, Rodrigues. C. I. S, Bortolloto. L. A, Gomes, M. A. M, Brandão, A. A., Feitosa. A. D. M, Machado, C. A, Figueiredo, C. E. P, Amoedo, C, Junior. D. M, Barbosa, E. C. D, Nobre, F, Guimarães, I. C. B, Martin, J. F. V, Toledo, J. C. Y, Magalhães, M. E.C, Neves, M. F. T, Jardim, P. C. B. V, Miranda, R. D. M., Póvoa, R. M. S (...), Nadruz, W (2021). Definição, Epidemiologia e Prevenção Primária. Diretrizes Brasileiras de Hipertensão Arterial – 2020. Arquivos Brasileiros Cardiologia. 2021; 116(3). https://doi.org/10.36660/abc.20201238
Brito, L. C, Azevêdo, L, Peçanha, T, Fecchio, R. Y, Rezende, R. A, da Silva, G. V, Pio-Abreu, A, Mion, D, Halliwill, J. R, & Forjaz, C. L. M. (2020). Effects of ACEi and ARB on post-exercise hypotension induced by exercises conducted at different times of day in hypertensive men. Clinical and Experimental Hypertension, 42(8), 722–727. https://doi.org/10.1080/10641963.2020.1783546
Costa, A. J. R, Ghidetti, C. A, Macedo, R. F, Godoy, J. S. R, & Teixeira, C. A. B. (2021). Tratamento não farmacológico da hipertensão na atenção primária: Uma revisão integrativa. Research, Society and Development, 10(7), e46110716644. https://doi.org/10.33448/rsd-v10i7.16644.
Costa, K, K, S, A, Gonçalves, A, Sobreira, V, Júnior, R, F. (2012). Hipotensão pós-exercício: considerações sobre intensidade, duração e método do exercício aeróbico. Brasília Med,49(1),49-54. https://rbm.org.br/details/157/pt-BR/hipotensao-pos-exercicio--consideracoes-sobre-intensidade--duracao-e-metodo-do-exercicio aerobico#:~:text=Investiga%C3%A7%C3%A3o%20recente%20verificou%20diferen%C3%A7as%20significativas,da%20hipotens%C3%A3o%20arterial%20p%C3%B3s%2Dexerc%C3%ADcio.
Ferreira, J. S, Diettrich, S. H. C., Pedro, D. A. (2015). Influência da prática de atividade física sobre a qualidade de vida de usuários do SUS. Saúde em Debate, 39(106), 792–801. https://doi.org/10.1590/0103-1104201510600030019
Filho, I.B, Jesus. L.L, Pagani. M.M (2015) Atividade física e seus benefícios à saúde. https://repositorio.faema.edu.br/bitstream/123456789/2715/1/ATIVIDADE%20F%c3%8dSICA%20E%20SEUS%20BENEF%c3%8dCIOS%20%c3%80%20SA%c3%9aDE.pdf
Jimenez, M, R, Palomo, F, M, Ortega, J. F, Rodriguez, R, M (2019). Post-exercise Hypotension Produced by Supramaximal Interval Exercise is Potentiated by Angiotensin Receptor Blockers. International Journal of Sports Medicine, 40(12), 756–761. https://doi.org/10.1055/a-0927-6957
Jimenez, R. M, Palomo,F, M., Cabañas, A, M., Jimenez, L.A, Ortega, J. F., Rodriguez, R, M. (2021). Effects of antihypertensive medication and high‐intensity interval training in hypertensive metabolic syndrome individuals. Scandinavian Journal of Medicine & Science in Sports, 31(7), 1411–1419. https://doi.org/10.1111/sms.13949
Jimenez,R, M, Palomo, F, M., Ortega, J. F, Rodriguez, R .M (2018). Effects of intense aerobic exercise and/or antihypertensive medication in individuals with metabolic syndrome. Scandinavian Journal of Medicine & Science in Sports, 28(9), 2042–2051. https://doi.org/10.1111/sms.13218
Kubotani, K. P.S, Fernandes, D. R (2019). Utilização de fármacos vasodilatadores de ação direta e indireta no tratamento de hipertensão arterial: artigo de revisão. Revista Científica FAEMA, 10(1), 148–156. https://repositorio.faema.edu.br/bitstream/123456789/2448/1/Artigo.pdf
Longo, M. A. T, Martelli, A, & Zimmermann, A. (2011). Hipertensão arterial sistêmica: Aspectos clínicos e análise farmacológica no tratamento dos pacientes de um setor de psicogeriatria do Instituto Bairral de Psiquiatria, no município de Itapira, SP. Revista Brasileira de Geriatria e Gerontologia, 14(2), 271–284. https://doi.org/10.1590/S1809-98232011000200008
Maruf, F. A, Akinpelu, A. O, Salako, B. L, Akinyemi, J. O. (2016). Effects of aerobic dance training on blood pressure in individuals with uncontrolled hypertension on two antihypertensive drugs: A randomized clinical trial. Journal of the American Society of Hypertension, 10(4), 336–345. https://doi.org/10.1016/j.jash.2016.02.002
Maruf, F, Akinpelu, A, & Salako, B. (2013). Effects of aerobic exercise and drug therapy on blood pressure and antihypertensive drugs: A randomized controlled trial. African Health Sciences, 13(1), 1–9. https://doi.org/10.4314/ahs.v13i1.1
Nilson, E. A. F, Andrade, R. C. S, Brito, D. A, Lessa, M, O. (2020). Custos atribuíveis à obesidade, hipertensão e diabetes no Sistema Único de Saúde, Brasil, 2018. Revista Panamericana de Salud Pública, 44, 1. https://doi.org/10.26633/RPSP.2020.32
Oigman, W, Fritsch, M. T. (1998). Drogas que intervêm no sistema renina-angiotensina. Hiper Ativo 5(2), 7. http://departamentos.cardiol.br/dha/revista/5-2/drogas.pdf
Queiroz, A, Sousa, J, Silva, N, Tobaldini, E, Ortega, K, de Oliveira, E, Brum, P, Montano, N, Mion, D, Tinucci, T, Moraes, F, C. (2017). Captopril does not Potentiate Post-Exercise Hypotension: A Randomized Crossover Study. International Journal of Sports Medicine, 38(04), 270–277. https://doi.org/10.1055/s-0042-123044
Ribeiro, A, B, Viana, D, Coelho, E.B, Barbosa, E, Almeida, F, A, Feitosa, G, Moreno, H, Guimarães, J, I, Ribeiro, J, P, Ramirez, J, A, F, Martins, J, F, Santos, R, A, S (2010) Tratamento medicamentoso. VI Diretrizes Brasileiras de Hipertensão (17) 1. Revista brasileira hipertensão- Brazilian Journal of Hypertension. http://www.rio.rj.gov.br/dlstatic/10112/4446958/4111920/diretriz.pdf
Souza, M, T, Silva, M, D, Carvalho, R. (2010). Integrative review: What is it? How to do it? Einstein (São Paulo), 8(1), 102–106. https://doi.org/10.1590/s1679-45082010rw1134.
Toledo, M. T. T, Abreu, M. N, Lopes, A. C. S. (2013). Adesão a modos saudáveis de vida mediante aconselhamento por profissionais de saúde. Revista de Saúde Pública, 47(3), 540–548. https://doi.org/10.1590/S0034-8910.2013047003936
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 Wadson Souza da Silva; Cláudio Luiz Ferreira Júnior; Marco Fabrício Dias Peixoto
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
