Benefits of virtual reality in the treatment of patients with Parkinson's disease: literature review




Physiotherapy; Virtual reality exposure therapy; Parkinson’s disease; Health teaching.


Introduction: Parkinson’a disease (PD) is a neurodegenerative disease of the central nervous system, with a chronic and progressive character, the diagnosis of PD is clinical, having as main characteristic the combination of motor symptoms that include bradykinesia, rigidity, tremor and postural instability. Objectives: The objective of is study was to review literature data on the benefits of virtual reality treatment in PD. Methodology: This is qualitative literature review, carried out between January and April 2022, using original articles, case studies and experience reports, published in journals indexed in online databases. Line: Virtual Health Library (VHL), Pubmed and SciELO. Results: The analyzed Studies found varied results regarding the use of virtual reality assistive technologies(ART) and its benefits in the treatment of PD, which were related to topics such as prospective memory, brain activation and, more frequently, gait and balance training. Thus, the most significant results regarding the use of ART were related to gait and balance training. Conclusion: The use of ART can bring benefits in the treatment of Parkinson’s disease as it has shown significant results in gait training, improving balance and reducing the risk of falls.


Arufe-Giráldez, V. et al. (2021). Music Therapy and Parkinson’s Disease: A Systematic Review from 2015–2020. International Journal of Environmental Research and Public Health. 18(21)

Ayele, B.A., Zewde, Y. Z., Tafesse A., Sultan, A., Friedman. J. H., & Bower. J, H. (2021). Non-Motor Symptoms and Associated Factors in Parkinson's Disease Patients in Addis Ababa, Ethiopia: A Multicenter Cross-Sectional Study. Ethiop J Health Sci. 31(4):837-846. d10.4314/ejhs.v31i4.19.

Brandín-de la Cruz. N., Secorro. N., Calvo. S., Benyoucef. Y., Herrero. P., Bellosta-López. P. (2020). Immersive virtual reality and antigravity treadmill training for gait rehabilitation in Parkinson's disease: a pilot and feasibility study. Rev Neurol. Dec 16;71(12):447-454. Spanish, English. 10.33588/rn.7112.2020352.

Castro. R, H, A. (2012). Desenvolvimento de Aplicações com uso de Interação Natural: Um Estudo de Caso voltado para Vídeo Colaboração em Saúde. João Pessoa – PB: Universidade Federal da Paraíba.

De Melo, G., Kleiner, A., Lopes, J., Dumont, A., Lazzari, R. D., Galli, M., & Oliveira, C. S. (2018). Effect of virtual reality training on walking distance and physical fitness in individuals with Parkinson's disease. Neurorehabilitation, 42(4), 473–480. Https://

Del Din, S., Galna, B., Lord, S., Nieuwboer, A., Bekkers, E., Pelosin, E., Avanzino, L., Bloem, B. R., Olde Rikkert, M., Nieuwhof, F., Cereatti, A., Della Croce, U., Mirelman, A., Hausdorff, J. M., & Rochester, L. (2020). Falls Risk in Relation to Activity Exposure in High-Risk Older Adults. The journals of gerontology. Series A, Biological sciences and medical sciences, 75(6), 1198–1205.

Dockx, K., Bekkers, E. M., Van den Bergh, V., Ginis, P., Rochester, L., Hausdorff, J. M., Mirelman, A., & Nieuwboer, A. (2016). Virtual reality for rehabilitation in Parkinson's disease. The Cochrane database of systematic reviews, 12(12), CD010760.

Feng, H., Li, C., Liu, J., Wang, L., Ma, J., Li, G., Gan, L., Shang, X., & Wu, Z. (2019). Virtual Reality Rehabilitation Versus Conventional Physical Therapy for Improving Balance and Gait in Parkinson's Disease Patients: A Randomized Controlled Trial. Medical science monitor: international medical journal of experimental and clinical research, 25, 4186–4192.

Foster, E. R., McDaniel, M. A., & Rendell, P. G. (2017). Improving Prospective Memory in Persons With Parkinson Disease: A Randomized Controlled Trial. Neurorehabilitation and neural repair, 31(5), 451–461.

Ferraz, D. D., Trippo, K. V., Duarte, G. P., Neto, M. G., Bernardes Santos, K. O., & Filho, J. O. (2018). The Effects of Functional Training, Bicycle Exercise, and Exergaming on Walking Capacity of Elderly Patients With Parkinson Disease: A Pilot Randomized Controlled Single-blinded Trial. Archives of physical medicine and rehabilitation, 99(5), 826–833.

Gálvez, G., Recuero, M., Canuet, L., & Del-Pozo, F. (2018). Short-Term Effects of Binaural Beats on EEG Power, Functional Connectivity, Cognition, Gait and Anxiety in Parkinson's Disease. International journal of neural systems. 28(5), 1750055.

Lopes J. M. (2018). Is virtual reality really effective in Parkinson's disease? Arquivos de neuro-psiquiatria, 76(9), 642–643.

Maidan, I., Rosenberg-Katz, K., Jacob, Y., Giladi, N., Hausdorff, J. M., & Mirelman, A. (2017). Disparate effects of training on brain activation in Parkinson disease. Neurology, 89(17), 1804–1810.

Medeiros, Anna Carolina Soares. (2012). Interação Natural baseada em Gestos como Interface de Controle para Modelos Tridimensionais. João Pessoa – PB: Universidade Federal da Paraíba.

Nascimento, D. B.; Carvalho, G. F. J.; & Costa, R. M. E. M. (2008). ReabRA: Reabilitação Cognitiva através de uma aplicação de Realidade Aumentada. Rio de Janeiro: UERJ.

Pedroso, P. C. S., Ferreira, J. M. da S., & Sá, M. dos A. F. de. (2022). Analysis of the effectiveness of virtual reality exposure therapy on the balance of Parkinson’s patients: integrative review. Research, Society and Development, 11(3), e55311326987.

Radhakrishnan, D. M., & Goyal, V. (2018). Parkinson's disease: A review. Neurology India, 66(Supplement), S26–S35.

Radder, D., Lígia Silva de Lima, A., Domingos, J., Keus, S., van Nimwegen, M., Bloem, B. R., & de Vries, N. M. (2020). Physiotherapy in Parkinson's Disease: A Meta-Analysis of Present Treatment Modalities. Neurorehabilitation and neural repair, 34(10), 871–880.

Severiano, M., Zeigelboim, B. S., Teive, H., Santos, G., & Fonseca, V. R. (2018). Effect of virtual reality in Parkinson's disease: a prospective observational study. Arquivos de neuro-psiquiatria, 76(2), 78–84.

Steidl, E.M.S., Ziegler, J.R., e Ferreira, F.V., (2007). Doença de Parkinson: Revisão Bibliográfica., Disc. Scientia. Série: Ciências da Saúde, 8(1), 115-129.

Kim, A., Darakjian, N., & Finley, J. M. (2017). Walking in fully immersive virtual environments: an evaluation of potential adverse effects in older adults and individuals with Parkinson's disease. Journal of neuroengineering and rehabilitation, 14(1), 16.



How to Cite

BRITO, S. F. L. de .; SILVA, S. P. da .; SANTOS, M. R. da; TEIXEIRA, M. E. M. .; SALAZAR, A. S. .; FERNANDES, F. E. O. .; TEIXEIRA, F. T. A. .; ARAÚJO, G. A. F. B. .; CUNHA, F. V. M. Benefits of virtual reality in the treatment of patients with Parkinson’s disease: literature review. Research, Society and Development, [S. l.], v. 11, n. 7, p. e9611729709, 2022. DOI: 10.33448/rsd-v11i7.29709. Disponível em: Acesso em: 22 feb. 2024.



Health Sciences