Evaluation of mental health and the use of antidepressants and anxiolytics in young adults during the COVID-19 pandemic in Brazil
DOI:
https://doi.org/10.33448/rsd-v11i7.30095Keywords:
COVID-19; Pandemic; Mental health; Antidepressants; Anxiolytics; Health teaching.Abstract
The objective of the study was to assess the prevalence of anxious, depressive and stress symptoms, as well as the consumption of antidepressants and anxiolytics among young adults during the COVID-19 pandemic in Brazil. This is a cross-sectional study conducted online via social media involving individuals between 18 and 35 years old. Participants answered a sociodemographic questionnaire and were asked about the use of anxiolytics and antidepressants. Mental health was assessed using the DASS-21 scale. The sample was composed of 349 participants of both sexes, and 71 (20.3%) used antidepressants and/or anxiolytics during the pandemic. Of these, 20.5% used anxiolytics, 31.8% used antidepressants, and 28.4% used both concomitantly. The main anxiolytic drug reported was clonazepam, and the antidepressant, fluoxetine. About mental health, a prevalence of 27.5% anxious symptoms, 31.8% depressive symptoms, and 30.7% stress symptoms was found. The results also show that the prevalence of depressive symptoms and stress reached 51.3% and 50.0%, respectively, in the participants who, prior to the pandemic, were already using medication for depression control, while in the participants who reported taking medication for anxiety control prior to the pandemic, the prevalence of anxious symptoms was 61.0%, depressive 56.4%, and stress 57.1%. Thus, high prevalence of mental disorders and use of medications were found, and such findings serve as an alert for the development of specific interventions.
References
Abbing-Karahagopian, V., Huerta, C., Souverein, P. C., de Abajo, F., Leufkens, H. G., Slattery, J., Alvarez, Y., Miret, M., Gil, M., Oliva, B., Hesse, U., Requena, G., de Vries, F., Rottenkolber, M., Schmiedl, S., Reynolds, R., Schlienger, R. G., de Groot, M. C., Klungel, O. H., Staa, T. P. V., Dijk, L. V., Egberts, A. C. G., Gardarsdottir, H., & de Bruin, M. L. (2014). Antidepressant prescribing in five European countries: application of common definitions to assess the prevalence, clinical observations, and methodological implications. European Journal of Clinical Pharmacology, 70(7), 849-857. https://doi.org/10.1007/s00228-014-1676-z
Abdala, A. H. E. H., & Elnadeef, E. A. E. (2019). English language anxiety and stress among saudi students in the first year at college of sciences and arts in Dharan Aljanoob. International Journal of Linguistics, Literature and Translation, 2(1), 270-275. https://doi.org/10.32996/ijllt.2019.2.1.33
Barbosa, L. N. F., Melo, M. C. B. D., & Cunha, M. D. C. V. D., Albuquerque, E. N., Costa, J. M., & Silva, E. F. F. D. (2021). Frequência de sintomas de ansiedade, depressão e estresse em brasileiros na pandemia COVID-19. Revista Brasileira de Saúde Materno Infantil, 21, 413-419. https://doi.org/10.1590/1806-9304202100S200005
Bezerra, D. R. C. (2021). Práticas integrativas e complementares em saúde no isolamento social pela COVID-19 no Brasil. (Dissertação de Mestrado em Enfermagem). Universidade Federal Fluminense, Niterói, Brasil.
Barros, M. B. A., Lima, M. G., Malta, D. C., Szwarcwald, C. L., de Azevedo, R. C. S., Romero, D., Júnior, P. R. B. S., Azevedo, L. O., Machado, I. E., Damacena, G. N., Gomes, C. S., Werneck, A. O., da Silva, D. R. P., de Pina, M. F., & Gracie, R. (2020). Relato de tristeza/depressão, nervosismo/ansiedade e problemas de sono na população adulta brasileira durante a pandemia de COVID-19. Epidemiologia e Serviços de Saúde, 29(4), 1-7. https://doi.org/10.1590/S1679-49742020000400018
Brasil. (2021). COVID-19: Painel de Controle. https://covid.saude.gov.br/.
Brooks, S. K., Webster, R. K., Smith, L. E., Woodland, L., Wessely, S., Greenberg, N., & Rubin, G. J. (2020). The psychological impact of quarantine and how to reduce it: rapid review of the evidence. The Lancet, 395, 912-20. https://doi.org/10.1016/S0140-6736(20)30460-8
Colizzi, M., Sironi, E., Antonini, F., Ciceri, M. L., Bovo, C., & Zoccante, L. (2020). Psychosocial and behavioral impact of COVID-19 in autism spectrum disorder: An online parent survey. Brain Sciences, 10(6), 1-14. https://doi.org/10.3390/brainsci10060341
Conselho Federal de Farmácia - CFF. (2020). Venda de medicamentos psiquiátricos cresce na pandemia. http://covid19.cff.org.br/venda-de-medicamentos-psiquiatricos-cresce-na-pandemia/.
Duarte, M. Q., Santo, M. A. S., Lima, C. P., Giordani, J. P., & Trentini, C. M. (2020). COVID-19 e os impactos na saúde mental: uma amostra do Rio Grande do Sul, Brasil. Ciência & Saúde Coletiva, 25(9), 3401-3411. https://doi.org/10.1590/1413-81232020259.16472020
Dubey, S., Biswas, P., Ghosh, R., Chatterjee, S., Dubey, M. J., Chatterjee, S., Lahiri, D., & Lavie, C. J. (2020). Psychosocial impact of COVID-19. Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 14(5), 779–788. https://doi.org/10.1016/j.dsx.2020.05.035
Faro, A., Silva-Santos, L., Silva, M. C., & Vasconcelos, M. M. (2021). Meta-worry, anxiety and depression in the COVID-19 pandemic. Em SciELO Preprints. https://doi.org/10.1590/SciELOPreprints.2436
Goularte, J. F., Serafim, S. D., Colombo, R., Hogg, B., Caldieraro, M. A., & Rosa, A. R. (2020). COVID-19 and mental health in Brazil: Psychiatric symptoms in the general population. Journal of Psychiatric Research, 132, 32-37. https://doi.org/10.1016/j.jpsychires.2020.09.021
González-Sanguino, C., Ausín, B., Castellanos, M. À., Saiz, J., López-Gómez, A., Ugidos, C., & Muñoz, M. (2020). Mental health consequences during the initial stage of the 2020 coronavirus pandemic (COVID-19) in Spain. Brain, Behavior, and Immunity, 87(2020), 172-176. https://doi.org/10.1016/j.bbi.2020.05.040
Goyal, P., Choi, J. J., Pinheiro, L. C., Schenck, E. J., Chen, R., Jabri, A., Satlin, M. J., Campion, T. R. J., Nahid, M., Ringel, J. B., Hoffman, K. L., Alshak, M. N., Li, H. A., Wehmeyer, G. T., Rajan, M., Reshetnyak, E., Hupert, N., Horn, E. M., Martinez, F. J., Gulick, R. M., & Safford, M. M. (2020). Clinical characteristics of Covid-19 in New York City. The New England Journal of Medicine, 382(24), 2372–2374. https://doi.org/10.1056/NEJMc2010419
Hartmann, P. B. (2020). “Coronofobia”: O impacto da pandemia de Covid-19 na saúde mental. https://pebmed.com.br/coronofobia-o-impacto-da-pandemia-de-covid-19-na-saude-mental/.
Hasan, B., Mahi, M., Sarker, T., & Amin, R. (2021). Spillovers of the COVID-19 pandemic: Impact on global economic activity, the stock market, and the energy sector. Journal of Risk and Financial Management, 14(5), 1-18. https://doi.org/10.3390/jrfm14050200
Herrera-Paz, J. J., Bobadilla-Jacob, P., Igolnikof, D. B., García-Zamora, S., Sandoval, C., Cancer, M., Dávila, E. G., Wolff, S., Wolff, D., & Picco, J. M. (2020). Impacto psicosocial de la pandemia por COVID-19 en adultos de Buenos Aires. Revista Argentina de Cardiologia, 88(5), 454-459. http://dx.doi.org/10.7775/rac.es.v88.i5.18857
Hulley, S. B., Cummings, S. R., Browner, W. S., Grady, D. G., & Newman, T. B. (2015). Delineando a pesquisa clínica-4. Artmed Editora.
Instituto Brasileiro de Geografia e Estatística - IBGE. (2016). Síntese de indicadores sociais: Uma análise das condições de vida da população brasileira. Estudos & Pesquisas.
Karatzias, T., Shevlin, M., Murphy, J., McBride, O., Ben-Ezra, M., Bentall, R. P., Valliéres, F., & Hyland, P. (2020). Posttraumatic stress symptoms and associated comorbidity during the COVID‐19 pandemic in Ireland: A population‐based study. Journal of Traumatic Stress, 33(4), 365-370. https://doi.org/10.1002/jts.22565
Li, Y., Qin, Q., Sun, Q., Sanford, L. D., Vgontzas, A. N., & Tang, X. (2020). Insomnia and psychological reactions during the COVID-19 outbreak in China. Journal of Clinical Sleep Medicine, 16(8), 1417-1418. https://doi.org/10.5664/jcsm.8524
Lima, C. K. T., Carvalho, P. M. M., Lima, I. A. A. S., Nunes, J. V. A. O., Saraiva, J. S., Souza, R. I., Silva, C. G. L., & Neto, M. L. R. (2020). The emotional impact of Coronavirus 2019-nCoV (new coronavirus disease). Psychiatry Research, 287, 1-2. https://doi.org/10.1016/j.psychres.2020.112915
Mamun, M. A., & Griffiths, M. D. (2020). First COVID-19 suicide case in Bangladesh due to fear of COVID-19 and xenophobia: Possible suicide prevention strategies. Asian Journal of Psychiatry, 51, 1-2. https://doi.org/10.1016/j.ajp.2020.102073
Negretto, B. L., Kerber, N., Zoratto, G., Rodrigues, L., Braun, L. E., Kochler, J., Girardi, F. L., Weber, L. P., Picinin, V. D., Maciel, L., Labre, G. S., Costa, F. C. D., Siqueira, G. R., Andrade, E., Cecatto, G., da Costa, L. M. V., Paolini, P. H. H., Rodrigues, B. F., Bertolazi, A. N., Schuch, F. B., Costa, G. M., Hoffmann, M. S., Braga, A. C. S., de Oliveira, C. T., Magon, M. C., Veit, H., Zatt, W. B., Junior, J. D., de Mello, A. F., Marques, C., Zatti, C., Freitas, L. H. M., Both, L. M., Lima, L. F., de Mello, M. F., & Hauck, S. (2020). Monitoramento da evolução da sintomatologia pós-traumática, depressão e ansiedade durante a pandemia de covid-19 em brasileiros. https://www.covidpsiq.org/resultados.
Oliveira, de M. P. (2021). Prevalência de sintomas depressivos e ansiosos e fatores associados na população do Rio Grande do Sul durante a pandemia: Um inquérito telefônico. (Dissertação de Mestrado em Enfermagem). Universidade Católica de Pelotas, Pelotas, Brasil.
Ornell, F., Schuch, J. B., Sordi, A. O., & Kessler, F. H. P. (2020). Pandemia de medo e COVID-19: Impactos na saúde mental e possíveis estratégias. Debates em Psiquiatria, 10(2), 6-12. http://dx.doi.org/10.25118/2236-918X-10-2-2
Ozamiz-Etxebarria, N., Dosil-Santamaria, M., Picaza-Gorrochategui, M., & Idoiaga-Mondragon, N. (2020). Niveles de estrés, ansiedad y depresión en la primera fase del brote del COVID-19 en una muestra recogida en el norte de España. Cadernos de Saúde Pública, 36(4), 1-9. https://doi.org/10.1590/0102-311X00054020
Ponte, N. M., de Sousa, G. V. R., da Silva, F. U., da Costa, G. M. P., Oliveira, M. A. S., & do Val, D. R. (2020). Análise das prescrições e notificações de psicotrópicos dispensadas em uma farmácia da cidade de Sobral, Ceará, Brasil. Revista de Medicina da UFC, 60(4), 5-10. https://doi.org/10.20513/2447-6595.2020v60n4p5-10
Prado, M. A. M. B., Francisco, P. M. S. B., & Barros, M. B. A. (2017). Use of psychotropic medications in adults and elderly living in Campinas, São Paulo, Brazil: cross-sectional population-based study. Epidemiologia e Serviços de Saúde, 26(4), 1-11. https://dx.doi.org/10.5123/s1679-49742017000400007
Qiu, J., Shen, B., Zhao, M., Wang, Z., Xie, B., & Xu, Y. (2020). A nationwide survey of psychological distress among Chinese people in the COVID-19 epidemic: implications and policy recommendations. General Psychiatry, 33(2), 1-3. http://dx.doi.org/10.1136/gpsych-2020-100213
Salari, N., Hosseinian-Far, A., Jalali, R., Vaisi-Raygani, A., Rasoulpoor, S., Mohammadi, M., Rasoulpoor, S., & Khaledi-Paveh, B. (2020). Prevalence of stress, anxiety, depression among the general population during the COVID-19 pandemic: a systematic review and meta-analysis. Globalization and Health, 16(57), 1-11. https://doi.org/10.1186/s12992-020-00589-w
Silva-Costa, A., Griep, R. H., & Rotenberg, L. (2022). Percepção de risco de adoecimento por COVID-19 e depressão, ansiedade e estresse entre trabalhadores de unidades de saúde. Cadernos de Saúde Pública, 38(3), 1-13. https://doi.org/10.1590/0102-311X00198321
Schofield, M. J., & Khan, A. (2014). Predictors of prescribed medication use for depression, anxiety, stress, and sleep problems in mid-aged Australian women. Social Psychiatry and Psychiatric Epidemiology, 49(11), 1835-1847. https://doi.org/10.1007/s00127-014-0896-y
Sher, L. (2020). COVID-19, anxiety, sleep disturbances and suicide. Sleep Medicine, 70, 124. https://doi.org/10.1016/j.sleep.2020.04.019
Shi, Z., Qin, Y., Chair, S. Y., Liu, Y., Tian, Y., Li, X., Hu, W., & Wang, Q. (2021). Anxiety and depression levels of the general population during the rapid progressing stage in the coronavirus disease 2019 outbreak: a cross-sectional online investigation in China. BMJ Open, 11(5), 1-16. https://doi.org/10.1136/bmjopen-2021-050084
Shigemura, J., Ursano, R., Morganstein, J. C., Kurosawa, M., & Benedek, D. M. (2020). Public responses to the novel 2019 coronavirus (2019-nCoV) in Japan: Mental health consequences and target populations. Psychiatry and Clinical Neurosciences, 74(4), 281-282. https://doi.org/10.1111/pcn.12988
Twenge, J. M., & Joiner, T. E. (2020). U.S census bureau-assessed prevalence of anxiety and depressive symptoms in 2019 and during the 2020 COVID-19 pandemic. Depression and Anxiety, 37(10): 954-956. https://doi.org/10.1002/da.23077
Vignola, R. C. B., & Tucci, A. M. (2014). Adaptation and validation of the depression, anxiety and stress scale (DASS) to Brazilian Portuguese. Journal of Affective Disorders, 155, 104-109. https://doi.org/10.1016/j.jad.2013.10.031
Voitsidis, P., Gliatas, I., Bairachtari, V., Papadopoulou, K., Papageorgiou, G., Parlapani, E., Syngelakis, M., Holeva, V., & Diakogiannis, I. (2020). Insomnia during the COVID-19 pandemic in a Greek population. Psychiatry Research, 289(2020): 1-2. https://doi.org/10.1016/j.psychres.2020.113076
Wang, C., Pan, R., Wan, X., Tan, Y., Xu, L., Ho, C. S., & Ho, R. C. (2020). Immediate psychological responses and associated factors during the initial stage of the 2019 coronavirus disease (COVID-19) epidemic among the general population in China. International Journal of Environmental Research and Public Health, 17(5), 1729. https://doi.org/10.3390/ijerph17051729
World Health Organization - WHO. (2017). Depression and other common mental disorders: Global health estimates. Genebra: World Health Organization. https://apps.who.int/iris/handle/10665/254610
Zaami, S., Marinelli, E., & Varì, M. R. (2020). New trends of substance abuse during COVID-19 pandemic: An international perspective. Frontiers in Psychiatry, 11, 1-4. https://doi.org/10.3389/fpsyt.2020.00700
Zhang, J., Yang, Z., Wang, X., Li, J., Dong, L., Wang, F., Li, Y., Wei, R., & Zhang, J. (2020). The relationship between resilience, anxiety and depression among patients with mild symptoms of COVID-19 in China: A cross-sectional study. Journal of Clinical Nursing, 29(21-22): 4020-4029. https://doi.org/10.1111/jocn.15425
Zuanazzi, C. A., & Grazziotin, N. A. (2020). Análise da dispensação de antidepressivos e ansiolíticos em uma farmácia comercial do Noroeste do Rio Grande do Sul. Revista Perspectiva, 44(165): 153-160. https://doi.org/10.31512/persp.v.44.n.165.2020.80.p.153-160
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