Equine asthma in Brazil – a scoping review

Authors

DOI:

https://doi.org/10.33448/rsd-v11i8.30824

Keywords:

Endoscopy; Recurrent airway obstruction; Horses; Neutrophils; Inflammatory airway disease.

Abstract

Asthma is a chronic respiratory disease that can occur in horses of different breeds and ages. While its occurrence has been reported in many countries, its occurrence across Brazil is unclear. This review aimed to gather information about equine asthma from studies performed in Brazil by different groups and investigate a variety of horse populations. Articles published in peer-reviewed scientific journals, as well as information contained in dissertations and theses, were searched on PubMed, SciELO, Google Scholar, and the Brazilian government catalog of dissertations and theses. Fifteen studies were included in this review, and according to the published information, the authors identified equine asthma using clinical signs, endoscopic findings, and/or cytological examination of tracheal wash and/or bronchoalveolar lavage fluid. Studies have investigated horses of different breeds and activities (racehorses, police horses, riding horses, Crioulos horses, and others) and were performed in different regions with diverse climatic conditions. On the previous observed studies, the occurrence varied from 14.0% to 60.0%, with a mean occurrence of 24% for severe asthma. Other studies must be performed to further understand the occurrence of equine asthma in Brazil, according to different climatic regions.

References

Abreu, H.C. (2009). Problemas respiratórios e de claudicação em cavalos crioulos atletas. Thesis, Master of Veterinary Medicine, Universidade Federal de Santa Maria, Brasil.

Allen, K. J., Tennant, K. V., & Frankling, S. H. (2019). Effect of inclusion or exclusion of epithelial cells in equine respiratory cytology analysis. The Veterinary Journal 254, 105405. https://doi.org/10.1016/j.tvjl.2019.105405

Almeida, S.R.P., Rocha, D. C. C., Lopes, A. C. A. M., Villanova Junior, J. A., & Michelotto Junior, P. V. (2015). The use of tracheal wash and bronchoalveolar lavage in the clinical examination of coughing horses. Revista Acadêmica Ciência Animal 13, 81–89. https://doi.org/10.7213/academica.13.FC.AO08

Almeida, S.R.P., Bastos, F. Z., Barussi, F. C. M., Lessa, D. A. B., Alencar, N. X., & Michelotto Junior, P. V. (2018). Airway endoscopy and tracheal cytology of two-year-old Thoroughbred horses during the first year of race training. Comparative Exercise Physiology 14, 143–148. https://doi.org/10.3920/CEP180004

Amaral, P.C., Graça, F. A. S., Vianna, L. F. C. G., Borges, J. R. J., Ferreira, A. M., Pires, N. R., & Voss, C. (1999). Doença pulmonar obstrutiva crônica em eqüinos da Polícia Militar do Estado do Rio de Janeiro. Revista Brasileira de Ciência Veterinária 6, 77–83. https://doi.org/10.4322/rbcv.2015.140

Bedenice, D., Mazan M. R., & Hoffman, A. M. (2008). Association between cough and cytology of bronchoalveolar lavage fluid and pulmonary function in horses diagnosed with inflammatory airway disease. Journal of Veterinary Internal Medicine 22, 1022–1028. https://doi.org/10.1111/j.1939-1676.2008.0109.x

Bond, S., Léguillette, R., Richard, E. A., Couetil, L. L., Lavoie J-P., Martin, J. G., & Pirie, R. S. (2018). Equine asthma: Integrative biologic relevance of a recently proposed nomenclature. Journal of Veterinary Internal Medicine 32, 2088–2098. https://doi.org/10.1111/jvim.15302

Chirstley, R. & Rush, B.R. (2007). Inflammatory airway disease. Equine Respiratory Medicine and Surgery, 591–595.

Couetil, L.L., Hoffman, A. M., Hodgson, J., Buechner-Maxwell, V., Viel, L., Wood, J. L. N., & Lavoie, J-P. (2007). Inflammatory airway disease of horses. Journal of Veterinary Internal Medicine 21, 356–361. https://doi.org/10.1892/0891-6640(2007)21[356:IADOH]2.0.CO;2

Couetil,, L.L., Cardwell, J. M., Gerber, V., Lavoie, J-P., Léguillette, R., & Richard, E. A. (2016). Inflammatory airway disease of horses-revised consensus statement. Journal of Veterinary Internal Medicine 30, 503–515. https://doi.org/10.1111/jvim.13824

Couetil,, L.L., Cardwell, J. M., Léguillette, R., Mazan, M., Richard, E., Bienzle, D., Bullone, M., Gerber, V., Ivester, K., Lavoie, J-P., Martin, J., Moran, G., Niedzwiedz, A., Pusterla, N., & Swiderski, C. (2020). Equine Ashtma: Current Understanding and Future Directions. Frontiers in Veterinary Science 7, 450. https://doi.org/10.3389/fvets.2020.00450

Fernandes, W. R., Mori, E., & Sanches, A. (2000). Avaliação citológica de lavados traqueobrônquico e broncoalveolar em cavalos clinicamente sadios pelo método de coloração de Rosenfeld. Arquivo brasileiro de medicina veterinária e zootecnia 52, 604–609. https://doi.org/10.1590/S0102-09352000000600009

Gouvea, L.V., Bernardes, C., Helayel, M. J. S. A., Alencar, N. X., Costa, M. F. M., & Lessa, D, A, B. (2021). Equine Pasture Asthma in Brazil. Acta Scientiae Veterinarie 49 (suppl 1): 616.

GINA (2018). Global initiative for asthma: 2018. Global Strategy for Asthma Management and Prevention. Retrieved May 6, 2008, from http://www.ginasthma.org

Holcombe, S.J., Robinson, N. E., Derksen, F. J., Bertold, B., Genovese, R., Miller, R., De Feiter Rupp, H., Carr, E. A., Eberhart, S. W., Boruta, D., & Kaneene, J. B. (2006). Effect of tracheal mucus and tracheal cytology on racing performance in Thoroughbred racehorses. Equine Veterinary Journal 38, 300–304. https://doi.org/10.2746/042516406777749191

Hotchkiss, J.W., Reid, S. W. J., & Christley, R. M. (2007). A survey of horse owners in Great Britain regarding horses in their care. Part 2: Risk factors for recurrent airway obstruction. Equine Veterinary Journal 39, 301–308. https://doi.org/10.2746/042516407X180129

Ivester, K.M., Couetil, L. L., & Zimmerman, N. J. (2014). Investigating the link between particulate exposure and airway inflammation in the horse. Journal of Veterinary Internal Medicine 28, 1653–1665. https://doi.org/10.1111/jvim.12458

Kinnison, T. & Carwell, J.M. (2020). Conflict between direct experience and research-based evidence is a key challenge to evidence-based respiratory medicine on British racing yards. Frontiers in Veterinary Science 7, 266. https://doi.org/10.3389/fvets.2020.00266

Lavoie, J.-P. (2015). Is the time primed for equine asthma? Equine Veterinary Education 27, 225–226. https://doi.org/10.1111/eve.12332

Lessa, D.A.B., Machado, C. H., Duarte, C. S., Wachholz, L., Andrade Lima, J. R. P., & Fernandes, W. R. (2005). Enfermidades do trato respiratório posterior em eqüinos de equitação no Rio de Janeiro: Prevalência e aspectos clínico-laboratoriais. Revista Brasileira de Ciência Veterinária 12, 77–83. https://doi.org/10.4322/rbcv.2014.308

Malkides, N., Hughes, K. J., Hodgson, D. R., & Hodgson, J. L. (2003). Comparison of tracheal aspirates and bronchoalveolar lavage in racehorses 2. Evaluation of the diagnostic significance of neutrophil percentage. Australian Veterinary Journal 81, 685–687. https://doi.org/10.1111/j.1751-0813.2003.tb12540.x

Melo, U.P., Ferreira, C., & Palhares, M. S. (2007). Obstrução recorrente das vias aéreas em muares: Relato de três casos. Arquivo brasileiro de medicina veterinária e zootecnia 59, 627–633. https://doi.org/10.1590/S0102-09352007000300012

Michelotto Junior, P.V., Biava, J. S., Gonçalves, R. C., Cassou, F., Bonfá, A. F., & Machado, C. D. (2007). Aspirado traqueal de cavalos clinicamente sadios da raça quarto de milha após prova de três tambores. Archives of Veterinary Science 12, 1–7. https://doi.org/10.5380/avs.v12i2.9899

Michelotto, P.V., Muehlmann, L. A., Zanatta, A. L., Bieberdach, E. W. R., Kryczyk, M., Fernandes, L. C., & Nishiyama, A. (2011). Pulmonary inflammation due to exercise-induced pulmonary haemorrhage in Thoroughbred colts during race training. Veterinary Journal 190, e3–e6. https://doi.org/10.1016/j.tvjl.2010.08.009

Robinson, N. E. (2001). International Workshop on Equine Chronic Airway Disease. Michigan State University 16-18 June 2000. Equine Veterinary Journal. International Workshop on Equine Chronic Airway Disease Michigan State University 16 33, 5–19. https://doi.org/10.2746/042516401776767412

Rocha, J.M., Silva, J. C. F., Ferreira, H. N., Lima, P. F., & Manso Filho, H. C. (2014). Prevalência da obstrução recorrente das vias aéreas (ORVA) nos equinos da polícia militar do Estado do Rio Grande do Norte. Medicina Veterinaria (Brazil) 8, 7–10.

Rossi, H., Virtala, A-M., Raekallio, M., Rahkonen, E., Rajamaki, M. M., & Mykkanen, A. (2018). Comparison of tracheal wash and bronchoalveolar lavage cytology in 154 horses with and without respiratory signs in a referral hospital over 2009–2015. Frontiers in Veterinary Science 5, 61. https://doi.org/10.3389/fvets.2018.00061

Sad, E.P., Viscardi, V., Hess, T. M., Silva, E. G. A., Michelotto Junior, P. V., & Lessa, D. A. B. (2012). Avaliação endoscópica semiquantitativa de exsudato traqueobrônquico em equinos de equitação. Revista Acadêmica Ciencias Agrarias Ambientais 10, 237–241.

Sad, E.P., Alencar, N. X., Viscardi, V., Costa, M. F. M., Hess, T. M., & Lessa, D. A. B. (2013). Cytology profile and age influence in the equine bronchoalveolar lavage in healthy and asymptomatic inflammatory airway disease. Ciência Rural 43, 452–455.

Silva, M.M., Silveira, R. G., Kaiseler, P. H., Pimpão, C. T., & Michelotto Junior, P. V. (2011). Achados de exames endoscópicos em vias aéreas de cavalos de corrida da raça Puro Sangue Inglês e sua relação com a tosse. Ciencia Agrária Ambiental, 403–406.

Ter Woort, F., Caswell, J. L., & Arroyo, L. G. (2018). Histologic investigation of airway inflammation in postmortem lung samples from racehorses. American Journal of Veterinary Research 79, 342–347. https://doi.org/10.2460/ajvr.79.3.342

Tesarowski, D.B., Viel, L., & McDonnel, W. N. (1996). Pulmonary function measurements during repeated environmental challenge of horses with recurrent airway obstruction (heaves). American Journal of Veterinary Research 57, 1214–1219.

Tremblay, G.M., Ferland, C., Lapointe, J-M., Vrins, A., Lavoie, J-P., & Cormier, Y. (1993). Effect of stabling on bronchoalveolar cells obtained from normal and COPD horses. Equine Veterinary Journal 25, 194–197. https://doi.org/10.1111/j.2042-3306.1993.tb02941.x

Viscardi, V., Jorge, M. L L. A., Silva, K. M., Sad, E. P., Fonseca, A. B. M., Alencar, N. X., & Lessa, D. A. B. (2016). Alkaline phosphatase activity in airway fluid obtained by tracheal wash from adult horses. Veterinary Clinical Patholoy 45, 376–380. https://doi.org/10.1111/vcp.12360

Woods, P.S.A., Robinson, N. E., Swanson, M. C., Reed, C. E., Broadstone, R. V., & Derksen, F. J. (1993). Airborne dust and aeroallergen concentration in a horse stable under two different management systems. Equine Veterinary Journal 25, 208–213. https://doi.org/10.1111/j.2042-3306.1993.tb02945.x

Xavier, M.O., Nogueira, C. E. W., Meirelles, M., Fernandes, W. R., Andreolla, H., Severo, L. C., Pasqualotto, A. C., & Meireles, M. C. A. (2014). Fungi in the respiratory tract of horses with recurrent airway obstruction. Arquivo brasileiro de medicina veterinária e zootecnia 66, 1457–1463. https://doi.org/10.1590/1678-6552

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Published

19/06/2022

How to Cite

OLIVEIRA, T. M. .; MICHELOTTO JUNIOR, P. V. .; FERNANDES, W. R. .; CALOMENO, S. S. . Equine asthma in Brazil – a scoping review. Research, Society and Development, [S. l.], v. 11, n. 8, p. e30311830824, 2022. DOI: 10.33448/rsd-v11i8.30824. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/30824. Acesso em: 17 nov. 2024.

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Agrarian and Biological Sciences