Polypharmacy in the health of the elderly: integrative literature review

Authors

DOI:

https://doi.org/10.33448/rsd-v11i8.30968

Keywords:

Polypharmacy; Elderly; Medications; Multimorbidities.

Abstract

Introduction: In the elderly with multimorbidities, the use of polydrug therapy has shown to be a very relevant complication. The elderly who use an average of five drugs may increase the risk of malnutrition, pneumonia, hypoglycemia, reduced mobility, fractures, hospitalizations in general and hospitalizations with long term stay. Objective: To present scientific evidence available to date that shows an association between the use of several drugs and worsening health in the elderly with chronic diseases. Methodology: This is a literature review, conducted in the months of March and April 2022, in the following databases: National Library of Medicine (PubMed MEDLINE), Scientific Electronic Library Online (Scielo), Cochrane Database of Systematic Reviews (CDSR), Google Scholar, Virtual Health Library (VHL) and EBSCO Information Services. Results and discussions: Polymedication has become a habit and a growing challenge in clinical experience, affecting the elderly because they are more susceptible to chronic diseases. Among the diseases found, the most common were: cancer, neuropsychiatric diseases, diabetes mellitus, renal failure, and cardiovascular diseases. Besides advanced age, there are other influential factors in this problem, such as easy access to medication and lack of information. Final considerations: Although the natural aging process brings vulnerabilities to the health of the elderly, the prescription of drugs with harmful effects when used simultaneously, drug iatrogenesis, also generates adverse reactions. However, this can be avoided, based on the dissemination of studies on senescence and senility and responsible use of drugs.

References

Bordin, D. et al. (2021). Sarcopenia e Polifarmácia em idosos de uma comunidade rural. Editora Científica Digital, 1 ed, III vol., 56-79.

Cardoso, V. N. et al. (2020). A prevalência de polifarmácia em idosos e fatores associados: um estudo em unidades básicas de saúde do município de Palhoça- SC. Trabalho de Conclusão de Curso de Medicina - Universidade do Sul de Santa Catarina. Campus Pedra Branca. Palhoça-SC, 1-56.

Carvalho, G. A. O. et al. (2020). Oral manifestations arising from polypharmacy in the elderly of a public shelter in Teresina – Piauí. Research, Society and Development, 9 (7), 1-11.

Córralo, V. S., et al. (2018). Polifarmácia e fatores associados em idosos diabéticos. Revista de Salud Pública, 20 (8), 366-372.

Farias, N. A. S., et al. (2022). The influence of polypharmacy in elderly addressed to a family health unit in Porto Velho –RO. Brazilian Journal of Development, 8 (4), 27459-27488.

Lima, A.B.R. (2021). Polifarmácia em idosos na atenção primária. Trabalho de Conclusão de Curso -Universidade Federal do Paraná. Pós-Graduação em Atenção Básica. Setor de Ciências da Saúde. Curitiba. 1-76.

Marques, G. F. M., et al. (2018). Polifarmácia e medicamentos potencialmente inapropriados para idosos na enfermagem gerontológica. Revista Brasileira de Enfermagem, 71 (8), 2440-2446.

Marques, P. D. P., et al. (2020). Polifarmácia em idosos comunitários: resultados do estudo Fibra. Revista Brasileira de Geriatria e Gerontologia, 22 (8).

Marques, P. P. et al. (2019). Polypharmacy in community-based older adults: results of the Fibra study. Revista Brasileira de Geriatria e Gerontologia, 22 (5), 1-16.

Medeiros, M. G. M. et al. (2020). Implications of polypharmacy in elderly and the important role of pharmaceutical in this process. Brazilian Journal of Development, 6 (5), 23391-24404.

Mercadante, A. C. C. et al. (2021). Fatores determinantes da polifarmácia entre idosos residentes em um grande centro urbano da região sudeste do Brasil. Revista Valore, 6 (4), 167-182.

Oliveira, P. C. et al. (2021). Prevalência e Fatores Associados à Polifarmácia em Idosos Atendidos na Atenção Primária à Saúde em Belo Horizonte-MG, Brasil. Ciência & Saúde Coletiva, 26 (4), 1553-1564.

Romano-Lieber, N. S., et al. (2019). Sobrevida de idosos e exposição à polifarmácia no município de São Paulo: Estudo SABE. Revista Brasileira de Epidemiologia, 21 (3).

Scursel, C. (2021). Multimorbity and polypharmacy in elderly residents in the rural perimeter of the municipality of Seara-SC. Brazilian Journal of Development, 7 (11), 7308-7323.

Tiago, D. C. et al. (2020). A ocorrência de polifarmácia em idosos em hospital dia geriátrico. Revista Científica da FMC, 15 (1), 45-61.

Tinôco, E. E. A. et al. (2021). Polifarmácia em idosos: Consequências de polimorbidades. Braz. J. Surg. Clin. Res., 35 (2), 79-85.

Published

20/06/2022

How to Cite

CASTRO, N. F. de .; FIGUEIREDO, B. Q. de .; VIEIRA, G. G.; NOGUEIRA, J. F.; LIMA, L. R.; QUEIROZ, L. G. de .; TOLENTINO, V. P. Polypharmacy in the health of the elderly: integrative literature review. Research, Society and Development, [S. l.], v. 11, n. 8, p. e31711830968, 2022. DOI: 10.33448/rsd-v11i8.30968. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/30968. Acesso em: 14 nov. 2024.

Issue

Section

Health Sciences