Infant herpes zoster: a 10-year retrospective study

Authors

DOI:

https://doi.org/10.33448/rsd-v11i9.31705

Keywords:

Herpes Zoster; Pediatrics; Varicella-Zoster Virus Infection.

Abstract

Introduction: The Varicella-Zoster Virus (VVZ) produces two clinical forms: Varicella and Herpes Zoster (HZ). Chickenpox is an acute illness associated with systemic symptoms and a rash that progresses to blisters and crusts. It is usually benign in children, but in adults it can lead to pneumonia or encephalitis, permanent sequelae, and death. Objectives: To analyze the prevalence of HZ and the clinical characteristics of cases treated at a referral hospital in the city of Fortaleza - CE during the years 2009-2019. Methods: Retrospective, cross-sectional and descriptive study that aims to analyze the medical records of pediatric patients who were treated at the Hospital São José de Diseases Infectious from 2009 to 2019. Discussion: It is known that HZ is a relatively frequent disease in the population, affecting several individuals at some point in their lives. Of this total, up to 3% require hospitalization. Although most cases are cured in a few weeks, the clinical picture can evolve with severe manifestations and complications, prolonging hospitalization time, generating more morbidities and higher costs to the health system. Conclusion: Given this scenario, it is important to know the profile of patients diagnosed with HZ due to the complications of the disease, which can have a great impact on quality of life, so that health promotion and intervention actions, such as vaccination against zoster, currently only available on the private network, may become increasingly frequent and available to the entire population.

References

Latin America: A systematic review and meta-analysis. PLOS ONE, 16(8), e0255877. https://doi.org/10.1371/journal.pone.0255877

Barros, M. S., Benício, J. A., Costa, L. J. da, Bonan, P. R. F., Silva, D. F., Albuquerque, A. C. L. de, & Soares, M. S. M. (2021). Herpes zoster com complicações em pacientes idosos. Research, Society and Development, 10(10), e208101018654–e208101018654. https://doi.org/10.33448/rsd-v10i10.18654

Cebrián-Cuenca, A. M., Díez-Domingo, J., San-Martín-Rodríguez, M., Puig-Barberá, J., & Navarro-Pérez, J. (2011). Epidemiology and cost of herpes zoster and postherpetic neuralgia among patients treated in primary care centres in the valencian community of Spain. BMC Infectious Diseases, 11(1). https://doi.org/10.1186/1471-2334-11-302

Fontelles, M. J., Simões, M. G., Farias, S. H., & Fontelles, R. G. S. (2009). Metodologia da pesquisa científica: diretrizes para a elaboração de um protocolo de pesquisa. Rev. para. med. https://pesquisa.bvsalud.org/portal/resource/pt/lil-58847

García Cenoz, M., Castilla, J., Montes, Y., Morán, J., Salaberri, A., Elía, F., Floristán, Y., Rodrigo, I., Irisarri, F., Arriazu, M., Zabala, A., & Barricarte, A. (2008). Incidencia de la varicela y el herpes zóster antes de la introducción de la vacunación sistemática infantil en Navarra, 2005-2006. Anales Del Sistema Sanitario de Navarra, 31(1), 71–80. https://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1137-66272008000100006

Herpes Zoster: Practice Essentials, Background, Pathophysiology. (2019, November 9). Medscape.com. https://emedicine.medscape.com/article/1132465-overview

Johnson, R. W., Alvarez-Pasquin, M.-J., Bijl, M., Franco, E., Gaillat, J., Clara, J. G., Labetoulle, M., Michel, J.-P., Naldi, L., Sanmarti, L. S., & Weinke, T. (2015). Herpes zoster epidemiology, management, and disease and economic burden in Europe: a multidisciplinary perspective. Therapeutic Advances in Vaccines, 3(4), 109–120. https://doi.org/10.1177/2051013615599151

Kanamori, K., Shoji, K., Kinoshita, N., Ishiguro, A., & Miyairi, I. (2019). Complications of herpes zoster in children. Pediatrics International, 61(12), 1216–1220. https://doi.org/10.1111/ped.14025

Katakam, B., Kiran, G., & Kumar, U. (2016). A prospective study of herpes zoster in children. Indian Journal of Dermatology, 61(5), 534. https://doi.org/10.4103/0019-5154.190121

Kawai, K., Gebremeskel, B. G., & Acosta, C. J. (2014). Systematic review of incidence and complications of herpes zoster: towards a global perspective. BMJ Open, 4(6), e004833–e004833. https://doi.org/10.1136/bmjopen-2014-004833

Koshy, E. (2018, April 30). Epidemiology, treatment and prevention of herpes zoster: A comprehensive review. Indian Journal of Dermatology, Venereology and Leprology. https://ijdvl.com/epidemiology-treatment-and-prevention-of-herpes-zoster-a-comprehensive-review/

Nair, P., & Patel, B. (2021). Herpes Zoster. StatPearls. https://www.statpearls.com/ArticleLibrary/viewarticle/22841

Pinto, I. C. T., Diniz, L. M. O., Carvalho, L. K. de, Resende, L. S., Silva, H. B. de A. e, Araújo, R. F. de A., Maia, M. M. M., & Ribeiro, J. G. L. (2021). NUMBER OF CASES OF VARICELLA AND HOSPITALIZATION IN A PEDIATRIC REFERENCE HOSPITAL IN BRAZIL AFTER INTRODUCING THE VACCINE. Revista Paulista de Pediatria, 39. https://doi.org/10.1590/1984-0462/2021/39/2019215

Portella, A. V. T., Souza, L. C. de B. de, & Gomes, J. M. A. (2013). Herpes-zóster e neuralgia pós-herpética. Revista Dor, 14(3), 210–215. https://doi.org/10.1590/S1806-00132013000300012

Purwoko, M. I. H., & Darmawan, H. (2020). Herpes Zoster: Clinical Manifestation, Treatment, and Prevention. Bioscientia Medicina: Journal of Biomedicine and Translational Research, 4(3), 34–44. https://doi.org/10.32539/bsm.v4i3.129

Saguil, A., Kane, S., Mercado, M., & Lauters, R. (2017). Herpes Zoster and Postherpetic Neuralgia: Prevention and Management. American Family Physician, 96(10), 656–663. https://www.aafp.org/pubs/afp/issues/2017/1115/p656.html

Shang, B.-S., Hung, C.-J. J., & Lue, K.-H. (2021). Herpes Zoster in an Immunocompetent Child without a History of Varicella. Pediatric Reports, 13(2), 162–167. https://doi.org/10.3390/pediatric13020022

Takayama, N., Takayama, M., & Takita, J. (2000). Herpes zoster in healthy children immunized with varicella vaccine. The Pediatric Infectious Disease Journal, 19(2), 169–170. https://doi.org/10.1097/00006454-200002000-00020

Varella, R. B., Pires, I. L., Saraiva, C. A., Guimarães, A. C. C., & Guimarães, M. A. A. M. (2005). Diagnóstico laboratorial da infecção pelo vírus herpes simples (HSV) em pacientes transplantados e não-transplantados. Jornal Brasileiro de Patologia E Medicina Laboratorial, 41(4). https://doi.org/10.1590/s1676-24442005000400007

Vujacich, C., Poggi, E., Cecchini, D., Luchetti, P., & Stamboulian, D. (2008). Herpes zoster: Epidemiología y clínica. Medicina (Buenos Aires), 68(2), 125–128. http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0025-76802008000200003

Weinmann, S., Naleway, A. L., Koppolu, P., Baxter, R., Belongia, E. A., Hambidge, S. J., Irving, S. A., Jackson, M. L., Klein, N. P., Lewin, B., Liles, E., Marin, M., Smith, N., Weintraub, E., & Chun, C. (2019). Incidence of Herpes Zoster Among Children: 2003–2014. Pediatrics, 144(1), e20182917. https://doi.org/10.1542/peds.2018-2917

Published

02/07/2022

How to Cite

MEDEIROS, L. de O.; MOREIRA, M. A. .; FERNANDES, P. H. P.; LEITE, R. D.; SOLON, F. R. N. Infant herpes zoster: a 10-year retrospective study. Research, Society and Development, [S. l.], v. 11, n. 9, p. e3211931705, 2022. DOI: 10.33448/rsd-v11i9.31705. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/31705. Acesso em: 14 nov. 2024.

Issue

Section

Health Sciences