Ketogenic diet and cancer treatment




Diet; Ketogenic diet; Cancer; Chronic diseases.


Faced with an expressive increase in the last decades in the case of cancer in the world population, the need for a dietary strategy supporting conventional treatment for patients diagnosed with cancer has become evident, with the aim of obtaining positive results in the fight against the disease. This literature review study aimed to present the ketogenic diet (KD) as a nutritional intervention and its proposed mechanisms against cancer cells, as well as to characterize limitations in the literature currently available. The studies were selected from the BIREME, PUBMED, ScienceDirect databases, as well as books, institutional and government websites; using descriptors such as: ketogenic diet; chronic diseases; cancer; cancer treatment and oxidative stress; they were used in the English language. It has been proposed that, in the absence of blood glucose, cancer cells decrease their proliferation and enter a state of oxidative stress, as a consequence of a high-fat, carbohydrate-deficient diet, thus making them more sensitive to standardized treatments. such as radiation and chemotherapy. However, there is a need for further studies in humans in order to obtain better results and conclusions regarding this nutritional intervention.

Author Biographies

Daniel Donato de Sousa, Centro Universitário de Brasília

Discente do Centro Universitário de Brasília

João Gabriel Toledo Pacheco Silva, Centro Universitário de Brasília

Discente do Centro Universitário de Brasília

Dayanne da Costa Maynard, Centro Universitário de Brasília

Departamento de Nutrição


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How to Cite

SOUSA, D. D. de .; SILVA, J. G. T. P. .; MAYNARD, D. da C. Ketogenic diet and cancer treatment. Research, Society and Development, [S. l.], v. 11, n. 9, p. e28211931806, 2022. DOI: 10.33448/rsd-v11i9.31806. Disponível em: Acesso em: 4 oct. 2022.



Health Sciences