Alopecia X in dogs: report of seven cases

Authors

DOI:

https://doi.org/10.33448/rsd-v11i10.32652

Keywords:

Alopecia; Hyperpigmentation; Hair cycle.

Abstract

Alopecia X (AX) is a non-inflammatory and non-pruritic skin disease characterized by progressive hair loss. The most commonly affected dogs are male Pomeranian, Chow-Chow and Poodles. Although there is a similarity with endocrinopathies that course with dermatological changes, AX does not bring systemic harm to affected dogs. The diagnosis is based on the exclusion of other diseases that lead to hair loss, in addition to systemic diseases. As it is a disease rarely reported in the literature, the objective of the present work is to make a retrospective study of seven cases of dogs with AX treated in clinical routine, from diagnosis to therapeutic results. At the time, the dogs received a similar therapeutic approach, which consisted of the orchiectomy process, followed by supplementation with omega-3 and vitamin complex. Only one dog was not neutered, due to constant platelet changes. Two dogs underwent the microneedling technique due to partial response to conventional treatment and only one of them showed complete repilation. From the above, it is considered that AX is a disease present in the dermatological routine of dogs and that the recognition of its lesion pattern is important for a better diagnostic and therapeutic direction. In addition, it was observed that, although all the therapies employed resulted in an improvement in hair growth, the therapeutic response was variable, so that some dogs may not show complete repilation. Further researches involving therapy comparison are encouraged in order to provide a better understading of their efficiency.

References

Adamo, I. D’A. (2008). Alopecia X: uma revisão de literatura. 2018. Trabalho de Conclusão de Curso (Graduação em Medicina Veterinária) – Universidade de Santo Amaro, São Paulo.

Albanese, F., Malerba, E., Abramo, F. Miragliotta, V., & Fracassi, F. (2014). Deslorelin for treatment of hair cycle arrest in intact male dogs. Veterinary Dermatology, 25, 519-e88.

Baptista, A. B. (2018). Avaliação do microagulhamento na terapêutica da alopecia X em cães da raça Spitz Alemão. 2018. 106 f. Dissertação (Mestrado em Medicina Veterinária e Bem-estar Animal) – Programa de Pós-Graduação em Medicina Veterinária e Bem-estar Animal, Universidade Santo Amaro, São Paulo.

Bourguignon, E., Guimarães, L.D., Ferreira, T.S., & Favarato, E.S. (2013). Dermatology in dogs and cats. Insigths from Veterinary Medicine, 1, 1-33.

Brooks, W. (2003). Alopecia X is a pattern of baldness. Veterinary Partner, 1-4.

Carvalho, J.C., Branco, M.C., Guedes, R.F.M., Oliveira, A.T.C., Carvalho, V.M., & Ferreira, T.C. (2020) Técnica de microagulhamento para tratamento de alopecia X em cães. Ciência Animal, 30, 138-144.

Cerundolo, R., Lloyd, D.H., Persechino, A., Evans, H., & Cauvin, A. (2004). Treatment of canine alopecia X with trilostane. Veterinary Dermatology, 15, 285-293.

Cerundolo, R., Bensignor, E., & Guaguére, E. (2008) Sex hormone dermatoses. In: E. Guarguére, E., Prélaud, P. A pratical guide in canine dermatology. Merial.

Cunha, F. K. A. (2015). Alopecia X responsiva à castração em cão da raça Spitz Alemão – relato de caso. Trabalho de Conclusão de Curso (Graduação em Medicina Veterinária) – Centro de Ciências Agrárias, Universidade Federal da Paraíba, 46p.

Ferreira, T. C., Carvalho, V. M., Cunha, M. G. M. C. M., & Nunes-Pinheiro, D. C. S. (2022). Canine Atopic Dermatitis: report of ten cases. Research, Society and Development, 11, e12411427258.

Frank, L. A., Hnilica, K. A., & Oliver, J. W. (2004). Adrenal steroid hormone concentrations in dogs with hair cycle arrest (alopecia x) before and during treatment with melatonin and mitotane. Veterinary Dermatology, 15, 278-284.

Frank, L.A. (2005) Growth hormone-responsive alopecia in dogs. Journal of the American Veterinary Medical Association, 226, 1494-1497.

Frank, L.A., & Watson, J.B. (2013). Treatment of alopecia X with medroxyprogesterone acetate. Veterinary Dermatology, 24, 624-e154.

Frank, L.A. (2017). Alopecia X in a Pomeranian. Clinicians Brief, 26-30.

Gondim, A. L. C. L., & Araujo, A. K. L. (2020). Alopecia X em cães: revisão. Pubvet, 5, 1-8.

Huang, H. P., Little, C. J. L., & McNeil, P. E. (2009). Histological changes in the external ear canal of dogs with otitis externa. Veterinary Dermatology, 20, 422-428.

Hnilica, A. K. (2012). Dermatologia de Pequenos Animais: atlas colorido e guia terapêutico, 3 ed. Rio de Janeiro: Elsevier editora Ltda, 300-303.

Koch, S. N., Torres, S. M. F., & Plumb, D. C. (2012). Canine and feline dermatology drug handbook. IWOA: John Wiley & Sons.

Medleau, L., & Hnilica, K. A. (2009). Dermatologia de pequenos animais: atlas colorido de guia terapêutico. 2 ed. São Paulo: Roca.

Miller, W. H., Griffin, C. E., & Campbell, K. L. (2013). Hair cycle harrest. In: Muller & Kirk`s Small animal dermatology. 7 ed. Missouri: Elsevier Mosby, 501-540.

Patterson, A. P. (2013). Practical approach to canine alopecia. Vetfolio, 1-10.

Rest, J. R., Lloyd, D. H., & Cerundolo, R. (2004). Histopathology of alopecia X. Veterinary Dermatology, 15, 20-40.

Stoll, S., Dietlin, C., & Nett-Metler, C. S. (2015). Microneedling as a successfull treatment for alopecia X in two Pomeranian siblings. Veterinary Dermatology, 26, 387-388.

Talarico, C. P. (2020) Alopecia X: relato de caso. Trabalho de Conclusão de Residência (Residência em Clínica Médica de Animais de Companhia) – Programa de Residência Uniprofissional em Medicina Veterinária, Faculdade de Medicina Veterinária da Universidade Federal de Uberlândia, Uberlândia.

Venâncio, J., Lima, R. K. R., Silva, R. R. F., & Holanda, R. (2016). Alopecia X: a evolução da etiopatogenia. MedVep Dermato – Revista de Educação Continuada em Dermatologia e Alergologia Veterinária, 4, 1-7.

Yu, A. (2015). Bald isn’t always beautiful – thinking outside the box part two – non-inflammatory alopecia – what’s new. In: Canadian Veterinarians.

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Published

26/07/2022

How to Cite

FERREIRA, M. A. de S. .; CARVALHO, V. M. de .; DUTRA, M. da S. .; RODRIGUES, F. R. N. .; VIANA, D. de A. .; FERREIRA, T. C. . Alopecia X in dogs: report of seven cases . Research, Society and Development, [S. l.], v. 11, n. 10, p. e159111032652, 2022. DOI: 10.33448/rsd-v11i10.32652. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/32652. Acesso em: 23 nov. 2024.

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Section

Agrarian and Biological Sciences