Incidence of resistant microorganisms after COVID-19 respiratory syndrome: An integrative review

Authors

DOI:

https://doi.org/10.33448/rsd-v11i10.32966

Keywords:

COVID-19; Bacterial resistance; Coinfection.

Abstract

This study aimed to analyze the incidence of bacterial resistance after COVID-19 infection. To carry out this integrative literature review, the study base was: Incidence of bacterial resistance after COVID infection. A survey of articles in the literature for this review was carried out in the following databases: LILACS, BVS (virtual health library), PubMed and Scielo. The following keywords and their combinations in Portuguese and English were used to search for articles: “COVID-19”, “bacterial resistance” and “coinfection”. All words were previously consulted in the Health Sciences Descriptors (Decs). The survey took place between April and June 2022. The predisposition to the development of bacteria and fungi is being evident in patients who contracted the coronavirus. COVID-19 patients have reported dimensions of complications, including respiratory distress syndrome, case fatality rates or other variables associated with these complications. Among the post-COVID-19 respiratory syndrome diseases, case studies of mitral valve prosthetic infective endocarditis, native valve infective endocarditis, bilateral endophthalmitis, mitral-aortic infective endocarditis complicated by heart failure and hemorrhagic stroke, mucormycoses, inflammatory syndrome were found. pediatric multisystem disease and lymphocytopenia in patients with thalassemia. These are recent reports, and further studies are still needed to correlate the extent of the severity of the influence of COVID-19 with bacterial resistance. We conclude that co-infections with various microorganisms are commonly found in patients infected with SARS-CoV-2 that significantly influence the severity and mortality rates of COVID-19.

Author Biographies

Eduarda Faria Arthur, Universidade Anhembi Morumbi

Graduanda em Biomedicina, Campus São José dos Campos

Marciany Aparecida Fragoso Moizes, Universidade Anhembi Morumbi

Graduanda em Biomedicina, Campus São José dos Campos

Rafaela Rodrigues Gonzaga, Universidade Anhembi Morumbi

Graduanda em Biomedicina, Campus São José dos Campos

Luciana Simi Venckunas, Universidade Anhembi Morumbi

Graduanda em Biomedicina, Campus São José dos Campos

Beatriz Franco e Silva, Universidade Anhembi Morumbi

Graduanda em Biomedicina, Campus São José dos Campos

Ana Luiza do Rosário Palma, Universidade Anhembi Morumbi

Docente no curso de Biomedicina, Campus São José dos Campos

References

Alizadehasl, A., Salehi, P., Roudbari, S., & Peighambari, M. M. (2020). Infectious endocarditis of the prosthetic mitral valve after COVID-19 infection. European Heart Journal, 41(48), 4604. doi: 10.1093/eurheartj/ehaa852.

Arora, N., Gudipati, A., Kundu, R., Prabhakar, N., Suri, V., Malhotra, P., & Jain, A. (2021). Post-COVID-19 mucormycosis presenting as chest wall cellulitis with mediastinitis. The Lancet Infectious Diseases, 21(11), 1611. doi: 10.1016/S1473-3099(21)00582-X.

Arora, U., Priyadarshi, M., Katiyar, V., Soneja, M., Garg, P., Gupta, I., Bharadiya, V., Berry, P., Ghosh, T., Patel, L., Sarda, R., Garg, S., Agarwal, S., Arora, V., Ramprasad, A., Kumar, A., Garg, R. K., Kodan, P., Nischal, N., Singh, G., Jorwal, P., Kumar, A., Baitha, U., Meena, V. P., Ray, A., Sethi, P., Xess, I., Vikram, N.,Sinha, S., Biswas, A., Thakar, A., Bhatnagar, S., Trikha, A., & Wig, N. (2022). Risk factors for Coronavirus disease-associated mucormycosis. Journal of Infection, 84(3), 383-390. doi: 10.1016/j.jinf.2021.12.039.

Balata, D., Mellergård, J., Ekqvist, D., Baranowski, J., Garcia, I. A., Volosyraki, M., & Broqvist, M. (2020). Non-bacterial thrombotic endocarditis: a presentation of COVID-19. European Journal of Case Reports in Internal Medicine, 7(8), 001811. doi: 10.12890/2020_001811.

Balows, A., Hausler Jr, W. J.,, Herrmann, K. L., Isenberg, H. D., & Shadomy, H. J. (1991). Manual of Clinical Microbiology. Revista do Instituto de Medicina Tropical de São Paulo, 33(6), 434-434, doi 10.1590/S0036-46651991000600015.

Becker, K., Heilmann, C., & Peters, G. (2014). Coagulase-negative staphylococci. Clinical Microbiology Reviews, 27(4), 870-926. doi: 10.1128/CMR.00109-13.

Campos, L. R., Almeida, R. G., Goldenzon, A. V., Rodrigues, M. C. F., Sztajnbok, F., Lino, K., Nogueira, K. T., Silva, R. M., & Fonseca, A. R. (2021). Síndrome inflamatória multissistêmica pediátrica (SIM-P) temporalmente associada a COVID-19: atualização. Residência Pediátrica, 11(1), 1-14. doi: 10.25060/residpediatr-2021.v11n1-574.

Cassettari, V. C., Strabelli, T., & Medeiros, E. A. S. (2005). Staphylococcus aureus bacteremia: what is the impact of oxacillin resistance on mortality ? The Brazilian Journal of Infectious Diseases, 9(1), 70-76. doi: 10.1590/S1413-86702005000100012.

Chambers, H. F., & Bayer, A. S. (2020). Native-valve infective endocarditis. New England Journal of Medicine, 383(6), 567–576. doi: 10.1056/NEJMcp2000400.

Chan, K. H., Joseph, O., Ahmed, E., Kommidi, A., Suleiman, A., Szabela, M. E., & Slim, J. (2021). Marantic endocarditis associated with COVID-19: a rare case report of a potentially deadly disease. European Journal of Case Reports in Internal Medicine, 8(3), 002409. doi: 10.12890/2021_002409.

Chen, N., Zhou, M., Dong, X., Qu, J., Gong, F., Han, Y., Qiu, Y., Wang, J., Liu, Y., Wei, Y., Xia, J., Yu, T., Zhang, X., & Zhang, L. (2020). Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. The Lancet, 395(10223), 507-513. doi: 10.1016/S0140-6736(20)30211-7.

Chennamchetty, V. K., Adimulapu, S., Kola, B. P., Padua, M. D., Ambika, C., Verma, M. K., & Rao, M. V. R. (2021). Post-COVID pulmonary mucormycosis - a case report. IP Indian Journal of Immunology and Respiratory Medicine, 6(1), 62-66. doi: 10.18231/j.ijirm.2021.014.

Choudhary, G. R., Aggarwal, A., Jain, V., & Jena, R. (2021). COVID-19 and fatal renal mucormycosis: contributory or coincidental? Indian Journal of Urology, 37(3), 270-273. doi: 10.4103/iju.iju_197_21.

Delpino, F. M., Caputo, E. L., Silva, M. C., Reichert, F. F., Nunes, B. P., Feter, N., Leite, J. S., Cassuriaga, J., Huckembeck, C. M., Alt, R., & Rombaldi, A. J. (2022) Incidence of multimorbidity and associated factors during the COVID-19 pandemic in Brazil: a cohort study. Sao Paulo Medical Journal, 140(3), 447-453. doi: 10.1590/1516-3180.2021.0518.R1.15092021.

Dumitru, I. M., Dumitrascu, M., Vlad, N. D., Cernat, R. C., Ilie-Serban, C., Hangan, A., Slujitoru, R. E., Gherghina, A., Mitroi-Maxim, C., Curtali, L., Carp, D. S., Dumitrescu, A., Mitan, R., Lesanu, R., & Rugina, S. (2021). Carbapenem-resistant klebsiella pneumoniae associated with COVID-19. Antibiotics, 10(5), 561. doi: 10.3390/antibiotics10050561.

Gelman, R., Potruch, A., Oster, Y., Ishay, Y., Gur, C., Beeri, R., & Strahilevitz, J. (2022). Native aortic valve Staphylococcus warneri endocarditis after COVID-19 infection: a case report and a review of literature. APMIS, 130(5), 270-275. doi: 10.1111/apm.13217.

Ginsburg, A. S., & Klugman, K. P. (2020). COVID-19 pneumonia and the appropriate use of antibiotics. The Lancet Glob Health, 8(12), e1453-e1454. doi: 10.1016/S2214-109X(20)30444-7.

Gopal, K., Mary, A., & Kulirankal, K. G. (2022). Multiple mural endocarditis in the setting of COVID-19. European Heart Journal: Cardiovascular Imaging, 23(4), e168. doi: 10.1093/ehjci/jeac007.

Hoque, M. N., Rahman, M. S., Ahmed, R., Hossain, M. S., Islam, M. S., Islam, T., Hossain, M. A., & Siddiki, A. Z. (2021). Diversity and genomic determinants of the microbiomes associated with COVID-19 and non-COVID respiratory diseases. Gene Reports, 23, 101200. doi: 10.1016/j.genrep.2021.101200.

Jain, M., Tyagi, R., Tyagi, R., & Jain, G. (2022). Post-COVID-19 gastrointestinal invasive mucormycosis. Indian Journal of Surgery, 84(3), 545-547. doi: 10.1007/s12262-021-03007-6.

Khalid, S., Siddique, R., Shaheen, S., Shahid, M. N., Shamim, Z., Khan, M. K. A., & Serçe, Ç. U. (2021). Current understanding of an emerging Coronavirus using in silico approach: severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). Brazilian Journal of Biology, 83, e247237. doi: 10.1590/1519-6984.247237.

Khatiwada, S., & Subedi, A.. (2020). Lung microbiome and coronavirus disease 2019 (COVID-19): possible link and implications. Hum Microb J, 17, 100073. doi: 10.1016/j.humic.2020.100073.

Koneman, E. W., Procop, G. W., Church, D. L., Hall, G. S., Janda, W. M., Schreckenberger, P. C., & Woods, G. L. (2001). Diagnóstico microbiológico, 5ed. Guanabara Koogan, cap. 11, parte 1.

Koupenova, M., & Freedman, J. E. (2020). Platelets and COVID-19: inflammation, hyperactivation and additional questions. Circulation Research, 127(11), 1419-1421. doi: 10.1161/CIRCRESAHA.120.318218.

Kumanayaka, D., Mutyala, M., Reddy, D. V., & Slim, J. (2021). Coronavirus disease 2019 infection as a risk factor for infective endocarditis. Cureus Journal of Medical Science, 13(5), e14813. doi: 10.7759/cureus.14813.

Li, Q., Guan ,X., Wu, P., Wang, X., Zhou, L., Tong, Y., Ren, R., Leung, K. S. M., Lau, E. H. Y., Wong, J. Y., & et al. (2020). Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia. The New England Journal of Medicine, 382(13), 1199-1207. doi: 10.1056/NEJMoa2001316.

Liew, Y., Lee, W. H. L., Tan, L., Kwa, A. L. H., Thien, S. Y., Cherng, B. P. Z., & Chung, S. J. (2020). Antimicrobial stewardship program: a vital resource for hospitals during the 2019 global coronavirus disease outbreak. International Journal of Antimicrobial Agents, 56(5), 106145. doi: 10.1016/j.ijantimicag.2020.106145.

Lopez, J. A., Ross, R. S., Fishbein, M. C., & Siegel, R. J. (1987). Nonbacterial thrombotic endocarditis: a review. American Heart Journal, 113(3), 773-84. doi: 10.1016/0002-8703(87)90719-8.

Mahmud, E., Dauerman, H. L., Welt, F. G. P., Messenger, J. C., Rao, S. V., Grines, C., Mattu, A., Kirtane, A. J., Jauhar, R., Meraj, P., Rokos, I. C., Rumsfeld, J. S., & Henry, T. D. (2020). Management of acute myocardial infarction during the COVID-19 pandemic: a consensus statement from the Society for Cardiovascular Angiography and Interventions (SCAI), the American College of Cardiology (ACC) and the American College of Emergency Physicians (ACEP). Catheterization and Cardiovascular Interventions, 96(2), 336-345. doi: 10.1002/ccd.28946.

Metwally, M. I., Mobashir, M., Sweed, A. H., Mahmoud, S. M., Hassan, A. G., ElKashishy, K., Eesa, M., Elnashar, I., Elmalt, A., Elsayed, A. I., Idris, S. K., & Elshetry, A. S. F. (2022). Post COVID-19 head and neck mucormycosis: MR imaging spectrum and staging. Academic Radiology, 29(5), 674-684. doi: 10.1016/j.acra.2021.12.007.

Mirzaei, R., Goodarzi, P., Asadi, M., Soltani, A., Aljanabi, H. A. A., Jeda, A. S., Dashtbin, S., Jalalifar, S., Mohammadzadeh, R., Teimoori, A., Tari, K., Salari, M., Ghiasvand, S., Kazemi, S., Yousefimashouf, R., Keyvani, H., & Karampoor, S. (2020). Bacterial co-infections with SARS-CoV-2. IUBMB Life, 72(10), 2097-2111. doi: 10.1002/iub.2356.

Montrucchio, G., Corcione, S., Sales, G., Curtoni, A., De Rosa, F. G, & Brazzi, L. (2020). Carbapenem-resistant klebsiella pneumoniae in ICU-admitted COVID-19 patients: keep an eye on the ball. Journal of Global Antimicrobial Resistance, 23, 398-400. doi: 10.1016/j.jgar.2020.11.004.

OPAS/OMS Brasil. (2019). Novo relatório pede ação urgente para evitar crise de resistência antimicrobiana. Disponível em: https://www.paho.org/bra/index.php

O'Toole, R. F. (2021). The interface between COVID-19 and bacterial healthcare-associated infections. Clinical Microbiology and Infection, 27(12), 1772-1776. doi: 10.1016/j.cmi.2021.06.001.

Ouarradi, A. E., Kantri, A., Agrad, K., Bensahi, I., Merzouk, F., Guennoun, Z., Makani, S., Jebbari, Y., Elkettani, C., & Sabry, M. (2021). Infective endocarditis following COVID-19 pneumonia: about two cases. The Pan African Medical Journal, 40(152). doi: 10.11604/pamj.2021.40.152.32071.

Pavlyshyn, H., Slyva, V., Dyvonyak, O., & Horishna, I. (2021). Multisystem inflammatory syndrome in children (MIS-C) temporally associated with SARS-CoV-2: the first clinical case in Ternopil, Ukraine. Germs, 11(1), 120-127. doi: 10.18683/germs.2021.1249.

Petrungaro, A., Quartarone, E., Sciarrone, P., & Rigoli, L. (2022). Post-COVID-19 lymphocytopenia and opportunistic pathogens infection in a thalassemia major patient. Thalassemia Reports, 12(2), 30-33. doi: 10.3390/thalassrep12020006.

Phua, J., Weng, L., Ling, L., Egi, M., Lim, C. M., Divatia, J. V., Shrestha, B. R., Arabi, Y. M., Ng, J., Gomersall, C. D., Nishimura, M., Koh, Y., & Du, B. (2020). Intensive care management of coronavirus disease 2019 (COVID-19): challenges and recommendations. The Lancet Respiratory Medicine, 8(5), 506-517. doi: 10.1016/S2213-2600(20)30161-2.

Rawson, T. M., Moore, L. S. P., Castro-Sanchez, E., Charani, E., Davies, F., Satta, G., Ellington, M. J., & Holmes, A. H. (2020). COVID-19 and the potential long-term impact on antimicrobial resistance. Journal of Antimicrobial Chemotherapy, 75(7), 1681-1684. doi: 10.1093/jac/dkaa194.

Ritchie, A. I., & Singanayagam, A. (2020). Immunosuppression for hyperinflammation in COVID-19: a double-edged sword? The Lancet, 395(10230), 1111. doi: 10.1016/S0140-6736(20)30691-7.

Rodrigues, M. G., Sekiguchi, W. K., Gonçalves, S., Casal, Y. R., Frassetto, F. P., Silva, V. N. G., Santo, M. P. E., & Magri, M. M. C. (2021). Loss of an eye to mucormycosis following corticosteroid therapy for COVID-19. Autopsy and Case Reports, 12, e2021345. doi: 10.4322/acr.2021.345.

Smeglin, A., Ansari, M., Skali, H., Oo, T. H., & Maysky, M. (2008). Marantic endocarditis and disseminated intravascular coagulation with systemic emboli in presentation of pancreatic cancer. Journal of Clinical Oncology, 26(8), 1383– 1385. doi: 10.1200/JCO.2007.12.9148.

Souza, M.T., Silva, M. D., & Carvalho, R. (2010). Revisão integrativa: o que é e como fazer. Einstein, 8(1), 102-106. doi: 10.1590/S1679-45082010RW1134.

Tenforde, M. W., Rose, E. B., Lindsell, C. J., Shapiro, N. I., Files, D. C., Gibbs, K. W., Prekker, M. E., Steingrub, J. S., Smithline, H. A., Gong, M. N., Aboodi, M. S., Exline, M. C., Henning, D. J., Wilson, J. G., Khan, A., Qadir, N., Stubblefield, W. B., Patel, M.M., Self, W. H., Feldstein, L. R., CDC COVID-19, & Response Team. (2020). Characteristics of adult outpatients and inpatients with COVID-19–11 academic medical centers, United States, March-May 2020. Morbidity and Mortality Weekly Report, 69(26), 841-846. doi: 10.15585/mmwr.mm6926e3.

Verma, A., & Rathi, B. (2022). Machine learning based predictive model and systems-level network of host-microbe interactions in post-COVID-19 mucormycosis. Microbial Pathogenesis, 162, 105324. doi: 10.1016/j.micpath.2021.105324.

Wang, D., Hu, B., Hu, C., Zhu, F., Liu, X., Zhang, J., Wang, B., Xiang, H., Cheng, Z., Xiong, Y., Zhao, Y., Li, Y., Wang, X., & Peng, Z. (2020). Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China. The Journal of the American Medical Association, 323(11), 1061-1069. doi: 10.1001/jama.2020.1585.

Wu, C., Chen, X., Cai, Y., Xia, J., Zhou, X., Xu, S., Huang, H., Zhang, L., Zhou, X., Du, C., Zhang, Y., Song, J., Wang, S., Chao, Y., Yang, Z., Xu, J., Zhou, X., Chen, D., Xiong, W., Xu, L., Zhou, F., Jiang, J., Bai, C., Zheng, J., & Song, Y. (2020). Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China. JAMA Internal Medicine, 180(7), 934-943. doi: 10.1001/jamainternmed.2020.0994.

Wu, Z., & McGoogan, J. M. (2020). Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the chinese center for disease control and prevention. The Journal of the American Medical Association, 323(13), 1239-1242. doi: 10.1001/jama.2020.2648.

Zhang, G., Hu, C., Luo, L., Fang, F., Chen, Y., Li, J., Peng, Z., & Pan, H. (2020). Clinical features and short-term outcomes of 221 patients with COVID-19 in Wuhan, China. Journal of Clinical Virology, 127, 104364. doi: 10.1016/j.jcv.2020.104364.

Zhang, T., Sun, L. X., & Feng, R. E. (2020). Comparison of clinical and pathological features between severe acute respiratory syndrome and coronavirus disease 2019. Chinese Journal of Tuberculosis and Respiratory Diseases, 43(6), 496–502. doi: 10.3760/cma.j.cn112147-20200311-00312.

Zhu, N., Zhang, D., Wang, W., Li, X., Yang, B., Song, J., Zhao, X., Huang, B., Shi, W., Lu, R., Niu, P., Zhan, F., Ma, X., Wang, D., Xu, W., Wu, G., Gao, GF., Tan, W., China Novel Coronavirus Investigating, & Research Team. (2020). A novel coronavirus from patients with pneumonia in China, 2019. New England Journal of Medicine, 382(8), 727-733. doi: 10.1056/NEJMoa2001017.

Zmaili, M. A., Alzubi, J. M., Kocyigit, D., Bansal, A., Samra, G. S., Grimm, R., Griffin, B. P., & Xu, B. (2021). A contemporary 20 year cleveland clinic experience of nonbacterial thrombotic endocarditis: etiology, echocardiographic imaging, management and outcomes. The American Journal of Medicine, 134(3), 361-369. doi: 10.1016/j.amjmed.2020.06.047.

Published

02/08/2022

How to Cite

ARTHUR, E. F. .; MOIZES, M. A. F. .; GONZAGA, R. R. .; VENCKUNAS, L. S. .; SILVA, B. F. e; PALMA, A. L. do R. . Incidence of resistant microorganisms after COVID-19 respiratory syndrome: An integrative review. Research, Society and Development, [S. l.], v. 11, n. 10, p. e340111032966, 2022. DOI: 10.33448/rsd-v11i10.32966. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/32966. Acesso em: 4 oct. 2022.

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Review Article