Clinicopathological aspects of myxosarcoma in a feline: case report

Authors

DOI:

https://doi.org/10.33448/rsd-v11i13.35042

Keywords:

Feline medicine; Cytology; Histopathology; Diagnosis; Myxoid matrix.

Abstract

Myxosarcomas are malignant mesenchymal neoplasms that commonly affect skin and subcutaneous tissue in the trunk and limbs, and are not common in cats. Therefore, this study aims to report a case of myxosarcoma in the inguinal region of a feline, emphasizing its topographic location, as well as its clinicopathological findings. The patient arrived for care at the Veterinary Hospital of the Passo Fundo University, complaining of intermittent claudication in the right thoracic limb, and the presence of a nodule in the inguinal region – both with rapid evolution. Aspiration cytology of the nodule showed a result suggestive of a soft tissue sarcoma. He also performed laboratory and imaging tests to rule out possible metastases in the lungs and in the limb in which he had claudication and was then referred for surgical excision. The nodule was referred for histopathological examination with a confirmatory result for myxosarcoma. Due to local recurrence after surgery, the non-performance of adjuvant therapies for tumor control due to the tutor's personal issues, and the general health status of the patient with the presence of intense pain, the feline was euthanized. Thus, it is concluded that myxosarcomas can present in any part of the body, commonly presenting local recurrences after removal and a low life expectancy. Furthermore, it is emphasized that the correlation between clinical presentation, cytology, histopathology and imaging tests further emphasize that cytology should be performed in all patients with cutaneous and subcutaneous nodules before undergoing any therapeutic procedure.

References

Burton, A. G. (2018). Integument. In: A. G. Burton. (Ed.). Clinical Atlas of Small Animal Citology. (pp. 63-105). Wiley Blackwell.

Dennis, R. (2008). Imaging features of orbital myxosarcoma in dogs. Veterinary Radiology and Ultrasound. 49(3), 256-263.

Dobromylskyj, M. J., Richards, V., & Smith, K. C. (2021). Prognostic factors and proposed grading system for cutaneous and subcutaneous soft tissue sarcomas in cats, based on a retrospective study. Journal of Feline Medicine and Surgery. 23(2), 168-174.

Eckstein, C., Guscetti, F., Roos, M., Martín de Las Mulas, J., Kaser‐Hotz, B., & Rohrer Bley, C. (2009). A retrospective analysis of radiation therapy for the treatment of feline vaccine‐associated sarcoma. Veterinary and Comparative Oncology. 7(1), 54-68.

Graf, R., Grüntzig, K., Hässig, M., Axhausen, K. W., Fabrikant, S., Welle, M., & Otto, V. (2015). Swiss feline cancer registry: a retrospective study of the occurrence of tumours in cats in Switzerland from 1965 to 2008. Journal of Comparative Pathology. 153(4), 266-277.

Gross, T. L., Ihrke, P. J., & Walder, E. J. (2007). Fibrous tumors. In: Gross, T. L., Ihrke, P. J. & Walder, E. J. (Eds.). Doenças da pele do cão e do gato. Diagnóstico clínico e histopatológico. 2, 750-761. Roca.

Guizelini, C. d. C., Mattei, D. R., Pupin, R. C., Martins, T. B., & Gomes, D. C. (2019). Osteopatia hipertrófica idiopática em um gato. Acta Scientiae Veterinariae. (Online). 373(47), 1-4.

Headley, S., Dos Reis, A. F., & Bracarense, A. F. R. (2011). Cutaneous myxosarcoma with pulmonary metastases in a dog. Journal of Comparative Pathology. 145(1), 31-34.

Ho, N. T., Smith, K. C., & Dobromylskyj, M. J. (2018). Retrospective study of more than 9000 feline cutaneous tumours in the UK: 2006–2013. Journal of Feline Medicine and Surgery. 20(2), 128-134.

Iqbal, W. (2020). A peculiar case of soft tissue sarcoma in a cat. The Canadian Veterinary Journal. 61(1), 79.

Iwaki, Y., Lindley, S., Smith, A., Curran, K. M., & Looper, J. (2019). Canine myxosarcomas, a retrospective analysis of 32 dogs (2003–2018). BMC Veterinary Research. 15(1), 1-7.

Madere, B. C., Dedeaux, A., Negrao Watanabe, T. T., Wakamatsu, N., Gaschen, L., Bennett, R., & Boudreaux, B. (2020). Myxosarcoma Associated with the Kidney in a Cat: Case Report. Journal of the American Animal Hospital Association. 56(2).

Martano, M., Morello, E., & Buracco, P. (2011). Feline injection-site sarcoma: past, present and future perspectives. The Veterinary Journal. 188(2), 136-141.

Mayer, M. N., Treuil, P. L., & LaRue, S. M. (2009). Radiotherapy and surgery for feline soft tissue sarcoma. Veterinary Radiology and Ultrasound. 50(6), 669-672.

Millanta, F., Asproni, P., Aquino, G., & Poli, A. (2020). Cytologic grading of canine and feline spindle-cell sarcomas of soft tissues and its correlation with histologic grading. Topics in Companion Animal Medicine. 41, 100458.

Murphy, S. (2006). Skin neoplasia in small animals 3. Common canine tumours. In Practice. 28(7), 398-402.

Phelps, H. A., Kuntz, C. A., Milner, R. J., Powers, B. E., & Bacon, N. J. (2011). Radical excision with five-centimeter margins for treatment of feline injection-site sarcomas: 91 cases (1998–2002). Journal of the American Veterinary Medical Association. 239(1), 97-106.

Sampaio, R. A. G., de Souza, A. A., Silva, T. d. S. L., Alves, A. P., dos Santos Ângelo, D. F., da Silva, C. P., & Lucena, R. B. (2019). Caracterização radiográfica, citomorfológica e histoquímica do mixossarcoma cutâneo em uma cadela. Acta Scientiae Veterinariae. 47(1), 355.

Silveira, M. F., Bonel, J., Pereira, S. M., & Fernandes, C. G. (2014). Sarcomas de tecidos moles em caninos e felinos: aspectos epidemiológicos e patológicos. Revista Acadêmica Ciência Animal. 12(3), 157-172.

Sykes, J. E., & Hartmann, K. (2014). Feline leukemia virus infection. Canine and feline infectious diseases. 224.

Wada, A., & Nagata, K. (2021). Huge myxosarcoma arising from the greater omentum in a dog. Journal of Veterinary Medical Science. 83(3), 461-468.

Zimmermann, K., Hossann, M., Hirschberger, J., Troedson, K., Peller, M., Schneider, M, & Wergin, M. (2017). A pilot trial of doxorubicin containing phosphatidyldiglycerol based thermosensitive liposomes in spontaneous feline soft tissue sarcoma. International Journal of Hyperthermia. 33(2), 178-190.

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Published

04/10/2022

How to Cite

SILVA, R. S. da .; SCHERER, I. F. .; COSTA , M. M. .; SANTOS , E. D. dos .; KLASER, B. W. .; SPLENGER, A.; GARCIA, C.; CARNEVALI, T. R. .; DUDA , N. C. B. . Clinicopathological aspects of myxosarcoma in a feline: case report. Research, Society and Development, [S. l.], v. 11, n. 13, p. e179111335042, 2022. DOI: 10.33448/rsd-v11i13.35042. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/35042. Acesso em: 22 nov. 2024.

Issue

Vol. 11 No. 13

Section

Agrarian and Biological Sciences

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Copyright (c) 2022 Rúbia Schallenberger da Silva; Isadora Fappi Scherer; Márcio Machado Costa ; Ezequiel Davi dos Santos ; Bruno Webber Klaser; Andressa Splenger; Cinthia Garcia; Taiane Rita Carnevali; Naila Cristina Blatt Duda

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