Quality of life, health and exercise in Parkinson's Disease during pre and post pandemic isolation





Parkinson's; Physical activity; Health; Pandemic; Covid-19.


Objective: To verify changes in health profile, quality of life and functionality, along with 2 years in individuals with Parkinson's diseases involved in a present and online exercise program. Methods: This is a longitudinal study with a quantitative data approach which was carried out in the city of Dracena, located in the interior of the state of São Paulo. Functionality and the general health profile were measured using Timed Up and Go test, blood pressure and PDQ-39 and, in addition to analysis of sociodemographic variables, between 2019 and 2020. The exercise intervention was carried out twice a week, one hour per session and consisted of gait activities, motor coordination, muscle strength, balance, and laterality. All analyses were performed using the SPSS program (version 20.0) and statistical significance was established at 5%. Results: In total, data from 9 people were monitored in person in 2019 and remotely in 2020. Changes were observed in hospital admission parameters, mean values of systolic and diastolic blood pressure, quality of life, mobility, assessment of daily life, communication, and body discomfort. Conclusion: The main result observed was the improvement in the biannual evaluations carried out with the participants in the observed period, covering physical, mental, and social improvement. The non-pharmacological approach showed positive results collaborating with the hypothesis that it is possible to delay or minimize the worsening of the disease and the development of future complications with the regular practice of physical exercises, resulting in improved quality of life.


Balsanelli, J. D. & Arroyo, C. T. (2015). Benefits of exercise in parkinson's disease. Revista Educação Física UNIFAFIBE, (3), 118-130.

Brasil, (2010). Atenção à Saúde da Pessoa Idosa e Envelhecimento. Ministério da saúde Série Pactos pela Saúde, 12.

Brod, L. S., Aldred, J. L. & Nutt, J. G. (2012). Are high doses of carbidopa a concern? A randomized clinical trial in Parkinson’s disease. Mov Disord, 750–753.

Burlá, C., Camarano, A. A., Kanso, S., Fernandes, D. & Nunes, R. (2013). Panorama prospectivo das demências no Brasil: um enfoque demográfico. Ciênc. Saúde coletiva.

Garcia, S., Albaghdadi, M. S., Meraj, P. M., Schmidt, C., Garberich, R., Jaffer, F. A., Dixon, S., Rade, J. J., Tannenbaum, M., Chambers, J., Huang, P. & Henry, T. (2020). Reduction in ST-Segment Elevation Cardiac Catheterization Laboratory Activations in the United States During COVID-19 Pandemic. Journal of the American College of Cardiology, 75(22), 2871–2872.

Guimarães, A. (2011). Atividade física habitual e desempenho motor de indivíduos com e sem a doença de Parkinson. Dissertação apresentada ao Programa de Pós-Graduação em Educação Física da Universidade Federal de Santa Catarina para obtenção do grau de Mestre em Educação Física; Área de concentração: Cineantropometria e Desempenho Humano. Florianópolis.

Hauser, R. A., Heritier, S., Rowse, G. J., Rewitt, L. A. & Isaacson, S. H. (2016). Droxidopa and Reduced Falls in a Trial of Parkinson Disease Patients With Neurogenic Orthostatic Hypotension. Clinical Neuropharmacology, 39(5).

Little, S. L., Pogosyan, A. & Neal, S. (2013). Adaptive Deep Brain Stimulation in Advanced Parkinson Disease. ANNALS of Neurology, 74(3).

Mak, M. K., Wong-Yu, I. S., Shen, X. & Chung, C. L. (2017). Long-term effects of exercise and physical therapy in people with Parkinson disease. Nature Reviews Neurology, 689–703.

Mao, Z. L. & Modi, N. B. (2016). Dose-Response Analysis of the Effect of Carbidopa-Levodopa Extended-Release Capsules (IPX066) in Levodopa-Naive Patients With Parkinson Disease. The Journal of Clinical Pharmacology, 974–982.

Melo, D. O., Ribeiro, T. B., Grezzana, G. B. & Stein, A. T. (2020). COVID-19 e doença hipertensiva no Brasil: possibilidade de uma tempestade perfeita. Revista Brasileira de Epidemiologia.

Mizuno, Y., Hattori, N., Kondo, T., Nomoto, M., Origasa, H., Takahashi, R., Yamamoto, M. & Yanagisawa, N. (2017). A Randomized Double-Blind Placebo-Controlled Phase III Trial of Selegiline Monotherapy for Early Parkinson Disease. Clinical Neuropharmacology, 40(5).

Paula, F. R., Lima, L. O., Salmela, L. F. T. & Cardoso, F. (2022). Aerobic exercise and muscular strengthening improve functional performance in Parkinson's disease. Fisioter. Mov.

Reuter, I. M., Engelhardt, K., Stecker, K. & Baas, H. (1999). Therapeutic value of exercise training in Parkinson’s disease. Med. Sci. Sports Exerc, 31(11), 1544–1549.

Richard, H., Mcdermott, M. & Kurlan, R. (2012). A randomized, double-blind, placebo-controlled trial of antidepressants in Parkinson disease. Neurology.

Rieder, C. R. D. M., Tumas, V., Borges, V., Krug, B. C. & Amaral, K. M. (2022). Doença de Parkinson. Protocolo Clínico e Diretrizes Terapêuticas, 211-233.

Silva, M. E., Silva, W. M. D., Silva, C. A. D. O., Silva, J. M. M., Silva, G. C. D. S., Silva, E. R. B. & Silva, N. A. M. (2020). Parkinson's disease, exercise and quality of life: a review. Brazilian Journal of Development, 6(9), 71478-71488.

Silva, W. B. H., Côrtes, E. M. P., Lima, T. A., Gouvêa, A. D. N., Marta, C. B., Ferreira, M. A., Machado, P. R. F., Silva, W. G. R., Paulo, A. O. D. S. & Oliveira, D. A. E. (2021). What did the COVID-19 pandemic do to systemic blood pressure? Glob Acad Nurs.

Soares, G. D. S. & Tartaruga, L. A. P. (2011). Parkinson’s disease and physical exercise: a literature review. Ciência em Movimento, (24).

Souza, C. F. M., Almeida, H. C. P., Sousa, J. B., Costa, P. H., Silveira, Y. S. S. & Bezerra, J. C. L. (2011). Parkinson’s disease and the Process of Aging Motor: Literature Review. Rev Neurocienc, 718-723.



How to Cite

BUENO, D. R. .; PEDRO, C. F. .; GUTIERRE, B. B. . Quality of life, health and exercise in Parkinson’s Disease during pre and post pandemic isolation. Research, Society and Development, [S. l.], v. 11, n. 14, p. e36111436043, 2022. DOI: 10.33448/rsd-v11i14.36043. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/36043. Acesso em: 4 dec. 2023.



Health Sciences