Comparative study between salicylic acid and mandelic acid superficial chemical peelings in the treatment of acne vulgar: a bibliographic review

Authors

DOI:

https://doi.org/10.33448/rsd-v11i14.36589

Keywords:

Acne vulgaris; Chemexfoliation; Salicylic acid; Mandelic acids; Therapeutics.

Abstract

Introduction: Acne is a common skin problem that occurs through inflammation in the hair follicles. It is a chronic disease that can generate inflammatory, non-inflammatory or a mixture of both. It can appear in different regions of the body, but it usually affects the face more, thus having different reasons for its appearance. Objective: To better understand how the use of these two acids through treatment with chemical peels acts on the lesions caused by acne and what are the benefits presented on the skin. Methodology: The study was based on the methodology of integrative literature review, being of an exploratory nature, which is the analysis of information addressed previously, in a systematic and orderly manner. Result: All peels were well tolerated at the end of the study. Regarding adverse effects, there were not many complications and they were easily reversed. Furthermore, it was found that in summer the lesions worsened to the detriment of sweat, causing an increase in sebum in the hair follicles, resulting in a greater growth of Cutibacterium acnes. Final considerations: With all the analyzes carried out, it is deduced that the effectiveness between salicylic acid and mandelic acid peels is proportional to being used to treat acne vulgaris.

References

Alagić, A., Alihodžić, S., Alispahić, N., Bečić, E., Smajović, A., Bečić, F., Spahić, L., Bećirović, L. Pokvić, G., & Badnjević, A. (2022). Application of artificial intelligence in the analysis of the facial skin health condition. IFAC-PapersOnLine, 55(4), 31-37.

Bernardes, N.B., Andrade, P.H.S., Santos, T.G., Lélis, B.D.B., de Sá, O.R., Araújo, L.M.S., & da Silva, P.G. (2021). O peeling químico associado à acne vulgar ativa: uma revisão integrativa / chemical peeling associated with acne vulgar acne: an integrative review. Brazilian Journal Of Development, 7(7), 75438-75466.

Cunha, B., & Ferreira, L. (2018). Peeling de Ácido Salicílico no Tratamento da Acne: Revisão Baseada em Evidências Clínicas. Id on Line. Revista de psicologia, 12(42), 383-398.

Dayal, S., Dudeja, K., & Sahu, P. (2019). Comparative study of efficacy and safety of 45% mandelic acid versus 30% salicylic acid peels in mild‐to‐moderate acne vulgaris. Journal Of Cosmetic Dermatology, 19(2), 393-399.

de Oliveira, A.Z, Torquetti, C.B., & do Nascimento, L.P.R. (2020). O tratamento da acne associado à limpeza de pele / Acne treatment associated with skin cleaning. Revista Brasileira Interdisciplinar de Saúde, 2(3):60-6

de Souza, C.R., Ramos, E.V., Torres, K.U.F., de Souza, L.M.N., & de Araújo, M.M.M. (2020). Microagulhamento nas cicatrizes de Acne/ Microneedling in Acne Scars. Revista Brasileira Interdisciplinar de Saúde, 2(3): 77-79.

Dréno, B. (2017). What is new in the pathophysiology of acne, an overview. Journal Of The European Academy Of Dermatology And Venereology, 31, 8-12.

Ercole, F.F, Melo, L.S.D, Alcoforado, C.L.G.C. (2014). Revisão integrativa versus revisão sistemática. Revista Mineira de Enfermagem, 18(1), 9-12.

Fasih, S., & Arif, A. B. (2016). Salicylic Acid Peel in the Treatment of Facial Acne Vulgaris. Pakistan Journal of Physiology, 12(4), 7-8.

Jartarkar, S., Gangadhar, B., Mallikarjun, M., & Manjunath, P. (2017). A randomized, single-blind, active controlled study to compare the efficacy of salicylic acid and mandelic acid chemical peel in the treatment of mild to moderately severe acne vulgaris. Clinical Dermatology, 1(1), 15-18.

Kanwar, I.L., Haider, T., Kumari, A., Dubey, S., Jain, P., & Soni, V. (2018). Models for acne: A comprehensive study. Drug Discoveries & Therapeutics, 12(6), 329-340.

Lee, K. C., Wambier, C. G., Soon, S. L., Sterling, J. B., Landau, M., Rullan, P., Brody, H. J., & Society, I. P. (2018). Basic chemical peeling: superficial and medium-depth peels. Journal of the American Academy of Dermatology, 81(2), 313-324.

Martire, A.C., & Guanaes, L.D. (2021). Avaliação da Eficácia e Segurança do Ácido Mandélico em Pacientes com Acne: Uma Revisão. Cadernos da Escola de Saúde, 21(1), 57-72.

Merck & Co. (2022). Tabelas - Classificação da gravidade da acne. MANUAL MSD Versão para Profissionais de Saúde. https://www.msdmanuals.com/pt-br/profissional/pages-with-widgets/tabelas?mode=list&order=bysection&keyword=acne

Nofal, E., Nofal, A., Gharib, K., Nasr, M., Abdelshafy, A., & Elsaid, E. (2018). Combination chemical peels are more effective than single chemical peel in treatment of mild-to-moderate acne vulgaris: A split face comparative clinical trial. Journal of Cosmetic Dermatology, 17(5), 802-810.

Nolasco, I. M. M., & Resende, J. R. (2020). Uso do ácido mandélico no tratamento de hipercromias pós-inflamatória: uma revisão de literatura. Scire Salutis, 10(2), 35-42.

O'connor, A. A., Lowe, P. M., Shumack, S., & Lim, A. C. (2017). Chemical peels: A review of current practice. Australasian Journal of Dermatology, 59(3), 171-181.

Orbe, M.C. (2017). Eficacia de los peeling químicos en el tratamiento del acné vulgar (Dissertação de Mestrado). Universitat de Barcelona, Espanha.

Ravikumar, B. & Devi, I. (2021). Role of Glycolic and Salicylic Acid Chemical Peel in the Management of Post-acne Pigmentation: a literature review. Annals Of Sbv, 10(1), 8-11.

Sarkar, R., Ghunawat, S., & Garg V. K. (2019). Comparative Study of 35% Glycolic Acid, 20% Salicylic–10% Mandelic Acid, and Phytic Acid Combination Peels in the Treatment of Active Acne and Postacne Pigmentation. Journal of Cutaneous and Aesthetic Surgery, 12(3), 158-163.

Sidiq, M., Vellaisamy, S.G., Gopalan, K., & Kandasamy, M. (2019). A comparative study of efficacy & tolerability of 30% salicylic acid versus 20% salicylic acid + 10% mandelic acid peel for acne vulgaris. Journal of Pakistan Association of Dermatologists, 29(2), 188-195

Soleymani, T., Lanoue, J., & Rahman, Z. (2018). A Practical Approach to Chemical Peels: A Review of Fundamentals and Step-by-step Algorithmic Protocol for Treatment. The Journal of clinical and aesthetic dermatology, 11(8), 21-28.

Sutaria A.H, Masood, S., & Schlessinger, J. (2022). Acne Vulgaris. StatPearls [Internet].

Truchuelo, M., Cerdá, P., & Fernández, L.F. (2017). Chemical Peeling: A Useful Tool in the Office. Actas DermoSifiliográficas, 108(4), 315-322.

UNIFAL-MG. (2022). Histologia dos sistemas - Pele e Anexos. Histologia Interativa – Universidade Federal de Alfenas. https://www.unifal-mg.edu.br/histologiainterativa/pele-e-anexos/

Published

02/11/2022

How to Cite

LEANDRO, N. S. de O.; SILVA, T. F. dos S.; RAMOS, R. P. Comparative study between salicylic acid and mandelic acid superficial chemical peelings in the treatment of acne vulgar: a bibliographic review. Research, Society and Development, [S. l.], v. 11, n. 14, p. e448111436589, 2022. DOI: 10.33448/rsd-v11i14.36589. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/36589. Acesso em: 16 nov. 2024.

Issue

Section

Health Sciences