Natural products from the Brazilian Caatinga as a sustainable source of phytocosmetics: a review

Authors

DOI:

https://doi.org/10.33448/rsd-v11i17.36940

Keywords:

Caatinga; Plant extracts; Phytocosmetics; Skincare.

Abstract

Natural extracts are described in the literature as biomolecules that have, among others, antioxidant and photoprotective properties. In addition, other advantages allow its use, such as low toxicity and high biodegradability. The skin is an organ that is constantly exposed to oxidative stress, including ultraviolet (UV) radiation, air pollutants and chemicals. These factors directly lead to premature skin aging. The interest in active substances from Brazilian biodiversity, especially the Caatinga Biome, highlighting the attention and research of the pharmaceutical sector and cosmetic industries, to study the insertion of natural biomolecules of plant origin, to demonstrate to consumers the safety and efficacy of these products. However, the objective of this review is to present plants from the Brazilian Caatinga that have biological activities that act in the preventive process of skin care and that have potential for the production of phytocosmetics. This integrative review was produced through a search carried out from January to April 2022. This bibliographic search was carried out in specialized databases (PubMed, Scopus and Science Direct), the manuscript selection was based on the inclusion criteria: articles with studies of plants collected in the region of the Caatinga Biome for the development or tests for skincare in the cosmetic area (in vivo and/or in vitro) with natural extracts that contain keywords in the title, abstract or full text, in the years between 2010 and 2022. Presenting results for the antioxidant, photoprotective and cytotoxicity assays of plants of the Arecaceae family.

References

Aline, M. S., Cludio, H. de A. O., Csar, C. L. F., Marcos, V. de O. C., Francisco, F. M. da S., Maria, I. F. G., & Davide, R. (2017). Bromatological analysis, phytochemical and antioxidant potential of carnauba (Copernicia prunifera (Mill.) HE Moore) fruit. African Journal of Food Science, 11(11), 353–361.

Almeida, J. (2019). Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME): um breve histórico, principais avanços e perspectivas. Revista Virtual de Qu’imica, 11(2).

Almeida, M. R., Martinez, S. T., & Pinto, A. C. (2017). Chemistry of natural products: Plants that witness histories. Revista Virtual de Quimica, 9(3), 1117–1153.

Alves, P. v, Querino, C. A. S., Rizzuti, B. F., Vaz, M. A. B., Querino, J. K. A. da S., & Pinho, J. A. do N. (2021). The importance of the concept of solar radiation in basic education: the perception of high school students about the theme. Revista Brasileira de Ensino de F’isica, 43.

Amendoeira, F. C., Frutuoso, V. S., Chedier, L. M., Pearman, A. T., Figueiredo, M. R., Kaplan, M. A. C., Prescott, S. M., Bozza, P. T., & Castro-Faria-Neto, H. C. (2005). Antinociceptive effect of Nidularium procerum: a Bromeliaceae from the Brazilian coastal rain forest. Phytomedicine, 12(1–2), 78–87.

Andrade, J. C., da Silva, A. R. P., dos Santos, A. T. L., Freitas, M. A., de Matos, Y. M. L. S., Braga, M. F. B. M., Bezerra, C. F., Gonçalo, M. I. P., Gomez, M. C. V., Rolóm, M., & others. (2019). Chemical composition, antiparasitic and cytotoxic activities of aqueous extracts of Ziziphus joazeiro Mart. Asian Pacific Journal of Tropical Biomedicine, 9(5), 222.

Aziz, F. M., Darweesh, M. J., Rahi, F. A., & Saeed, R. T. (2014). In vivo and in vitro studies of a polar extract of Helianthus annuus (Sunflower) seeds in treatment of Napkin Dermatitis. International Journal of Pharmaceutical Sciences Review and Research, 24(2), 1–3.

Barbosa, H. M., NASCIMENTO, J. N., Araujo, T. A. S., Duarte, F. S., Albuquerque, U. P., Vieira, J. R. C., Santana, E. R. B. D. E., Yara, R., Lima, C. S. A., Gomes, D. A., & others. (2016). Acute toxicity and cytotoxicity effect of ethanolic extract of Spondias tuberosa Arruda bark: hematological, biochemical and histopathological evaluation. Anais Da Academia Brasileira de Ciências, 88, 1993–2004.

Barman, K., Asrey, R., & Pal, R. K. (2011). Putrescine and carnauba wax pretreatments alleviate chilling injury, enhance shelf life and preserve pomegranate fruit quality during cold storage. Scientia Horticulturae, 130(4), 795–800.

Bendaoud, H., Romdhane, M., Souchard, J. P., Cazaux, S., & Bouajila, J. (2010). Chemical composition and anticancer and antioxidant activities of Schinus molle L. and Schinus terebinthifolius Raddi berries essential oils. Journal of Food Science, 75(6), C466–C472.

Benzidia, B., Barbouchi, M., Hammouch, H., Belahbib, N., Zouarhi, M., Erramli, H., Daoud, N. A., Badrane, N., & Hajjaji, N. (2019). Chemical composition and antioxidant activity of tannins extract from green rind of Aloe vera (L.) Burm. F. Journal of King Saud University-Science, 31(4), 1175–1181.

Berlinck, R. G. S., Borges, W. de S., Scotti, M. T., & Vieira, P. C. (2017). A qu’imica de produtos naturais do Brasil do século XXI. Qu’imica Nova, 40, 706–710.

Bhattacharya, U., Mukhopadhyay, S., & Giri, A. K. (2011). Comparative antimutagenic and anticancer activity of three fractions of black tea polyphenols thearubigins. Nutrition and Cancer, 63(7), 1122–1132.

Bochner, R., Fiszon, J. T., Assis, M. A., & Avelar, K. E. S. (2012). Problemas associados ao uso de plantas medicinais comercializadas no Mercadão de Madureira, munic’ipio do Rio de Janeiro, Brasil. Revista Brasileira de Plantas Medicinais, 14, 537–547.

Brasil, C. F. do B. (2010). Ministério da Saúde. Agência Nacional de Vigilância Sanitária (ANVISA). In Brazilian Pharmacopeia, 5a ed. Atheneu.

Brito, S. M. O., AOBPB, M., de Oliveira, M. R. C., Vidal, C. S., de Lacerda Neto, L. J., Ramos, A. G. B., da Cruz, L. P., Nascimento, E. A., da Costa, J. G. M., Coutinho, H. D. M., & others. (2020). Gastroprotective and cicatrizing activity of the Ziziphus joazeiro Mart. leaf hydroalcoholic extract. Journal of Physiology and Pharmacology: An Official Journal of the Polish Physiological Society, 71(3).

Câmara, A. C. L., Gadelha, I. C. N., Castro, M. B., Medeiros, R. M. T., Riet-Correa, F., & Soto-Blanco, B. (2017). Embryotoxic effects of Poincianella (Caesalpinia) pyramidalis leaves on pregnant rats. Journal of Veterinary Diagnostic Investigation, 29(2), 137–142.

Campos, S. C., Silva, C. G., Campana, P. R. v, & Almeida, V. L. (2016). Toxicidade de espécies vegetais. Revista Brasileira de Plantas Medicinais, 18, 373–382.

Carlini, E. A., Duarte-Almeida, J. M., & Tabach, R. (2013). Assessment of the Toxicity of the Brazilian Pepper Trees Schinus terebinthifolius Raddi (Aroeira-da-praia) and Myracrodruon urundeuva Allemão (Aroeira-do-sertão). Phytotherapy Research, 27(5), 692–698.

Cartaxo, S. L., de Almeida Souza, M. M., & de Albuquerque, U. P. (2010). Medicinal plants with bioprospecting potential used in semi-arid northeastern Brazil. Journal of Ethnopharmacology, 131(2), 326–342.

Cefali, L. C., Vazquez, C., Ataide, J. A., Figueiredo, M. C., Ruiz, A. L. T. G., Foglio, M. A., Lancellotti, M., & Mazzola, P. G. (2021). In vitro activity and formulation of a flavonoid-containing cashew pulp extract for the topical treatment of acne and the protection of skin against premature aging. Natural Product Research, 35(23), 5243–5249.

da Silva Andrade, L. B., da Silva Julião, M. S., Cruz, R. C. V., Rodrigues, T. H. S., dos Santos Fontenelle, R. O., & da Silva, A. L. C. (2018). Antioxidant and antifungal activity of carnauba wax powder extracts. Industrial Crops and Products, 125, 220–227.

da Silva Lima, A. D., de Sousa, R. G., & Lima, E. N. (2020). Incremento da atividade fotoprotetora e antioxidante de cosméticos contendo extratos vegetais da Caatinga.

Dalastra, V., Southier, N., Anaissi, F. J., Dalastra, J., & Yamazaky, R. K. (2019). Flavonoides presentes nos extratos da campomanesia xanthocarpa Berg. Brazilian Journal of Development, 5(7), 8983–8991.

Damascena, N. P., Souza, M. T. S., Almeida, A. F., Cunha, R. S., Damascena, N. P., Curvello, R. L., Lima, A. C. B., Almeida, E. C. v, Santos, C. C. S., Dias, A. S., & others. (2014). Antioxidant and orofacial anti-nociceptive activities of the stem bark aqueous extract of Anadenanthera colubrina (Velloso) Brenan (Fabaceae). Natural Product Research, 28(10), 753–756.

Dantas, L. V. B., da Silva Lopes, F. F., Alves, D. R., Frota, L. S., Cardoso, A. L. H., & de Morais, S. M. (2020). Avaliação Fitoqu’imica, quantificação de Fenóis e Flavonóides totais, Atividade antioxidante e antiacetilcolinesterase do extrato etanólico Da Tal’isia esculenta (Pitomba). Brazilian Journal of Development, 6(8), 60597–60602.

de Albuquerque, U. P., de Medeiros, P. M., de Almeida, A. L. S., Monteiro, J. M., Neto, E. M. de F. L., de Melo, J. G., & dos Santos, J. P. (2007). Medicinal plants of the caatinga (semi-arid) vegetation of NE Brazil: a quantitative approach. Journal of Ethnopharmacology, 114(3), 325–354.

de Almeida Andrade, B., Corrêa, A. J. C., Gomes, A. K. S., da Silva Neri, P. M., Sobrinho, T. J. da S. P., de Sousa Araújo, T. A., de Amorim, E. L. C., & others. (2019). Photoprotective activity of medicinal plants from the caatinga used as anti-inflammatories. Pharmacognosy Magazine, 15(61), 356.

de Almeida, B. C., Araújo, B. Q., Carvalho, A. A., Freitas, S. D. L., Maciel, D. da S. A., Ferreira, A. J. S., Tempone, A. G., Martins, L. F., Alexandre, T. R., Chaves, M. H., & others. (2016). Antiprotozoal activity of extracts and isolated triterpenoids of ‘carnauba’(Copernicia prunifera) wax from Brazil. Pharmaceutical Biology, 54(12), 3280–3284.

de Almeida, C., e Silva, T. C. de L., de Amorim, E. L. C., Maia, M. B. de S., & de Albuquerque, U. P. (2005). Life strategy and chemical composition as predictors of the selection of medicinal plants from the caatinga (Northeast Brazil). Journal of Arid Environments, 62(1), 127–142.

de Araújo, A. D., da Silva Oliveira, F. G., Lacerda, F. F., da Silva, C. E. S., dos Santos, B. S., Bezerra-Filho, C. M., de Azevedo Ramos, B., Harand, W., da Silva, N. H., Paiva, P. M. G., & others. (2021). Phytochemical screening, in vitro antioxidant, photoprotective and hemolytic activities of ethyl acetate extracts of the fruits and branches from Spondias tuberosa (umbu). Research, Society and Development, 10(1), e38610111825–e38610111825.

de Assis, L. V. M., Tonolli, P. N., Moraes, M. N., Baptista, M. S., & de Lauro Castrucci, A. M. (2021). How does the skin sense sun light? An integrative view of light sensing molecules. Journal of Photochemistry and Photobiology C: Photochemistry Reviews, 47, 100403.

de Freitas Lins Neto, E. M., Peroni, N., & de Albuquerque, U. P. (2010). Traditional knowledge and management of Umbu (Spondias tuberosa, Anacardiaceae): an endemic species from the semi–arid region of Northeastern Brazil. Economic Botany, 64(1), 11–21.

de Lima-Saraiva, S. R. G., Saraiva, H. C. C., Silva, J. C., Neves, L. F., Damasceno, P. K. F., Branco, C. R. C., Branco, A., Amorim, E. L. C., & Almeida, J. R. G. S. (2014). Antinociceptive properties and acute toxicity of ethanol extract of Bromelia laciniosa Mart. ex Schult. f.(Bromeliaceae). Tropical Journal of Pharmaceutical Research, 13(10), 1659–1666.

de Oliveira Almeida, J. I., Costa, F., Paulino, C. G., de Oliveira Almeida, M. J., Damaceno, M. N., dos Santos, S. M. L., & de Farias, V. L. (2020). Efeito da pasteurização sobre os compostos bioativos e a atividade antioxidante de polpa de frutos de Ziziphus joazeiro Mart. Research, Society and Development, 9(5), e135953245–e135953245.

de Oliveira Araújo, M. S., das Dores Bezerra, T. M., da Silva, T. P., Silva, T. A., & Evangelista, G. B. B. (2020). USO DE FITOCOSMÉTICOS NO TRATAMENTO DA ACNE. Revista Brasileira Interdisciplinar de Saúde.

de Oliveira, J. C. G., Linhares, M. G., Linhares, L. G., Câmara, L. M. A., Bertini, L. M., & Alves, L. A. (2020). Capacidade antioxidante e caracterização fitoqu’imica de Mimosa caesalpiniaefolia. Research, Society and Development, 9(8), e915986555–e915986555.

de Queiroz, A. C., de Lira, D. P., Dias, T. de L. M. F., de Souza, É. T., da Matta, C. B. B., de Aquino, A. B., Silva, L. H. A. C., da Silva, D. J. C., Mella, E. A. C., de Fátima Agra, M., & others. (2010). The antinociceptive and anti-inflammatory activities of Piptadenia stipulacea Benth.(Fabaceae). Journal of Ethnopharmacology, 128(2), 377–383.

de Sousa Araújo, T. A., Alencar, N. L., de Amorim, E. L. C., & de Albuquerque, U. P. (2008). A new approach to study medicinal plants with tannins and flavonoids contents from the local knowledge. Journal of Ethnopharmacology, 120(1), 72–80.

de Souza, T. de F. G., Pierdoná, T. M., Macedo, F. S., de Aquino, P. E. A., Rangel, G. de F. P., Duarte, R. S., de Barros Viana, G. S., Alves, A. P. N. N., Montenegro, R. C., Wilke, D. V., & others. (2020). Human keratinocyte (HaCaT) stimulation and healing effect of the methanol fraction from the decoction from leaf from Sideroxylon obtusifolium (Roem. & Schult.) TD Penn on experimental burn wound model. BioRxiv.

dos Santos, L. de O., Reis, M. R., Ogava, L. E., Leão, K. V., Machado, L. L., & de Lira, S. P. (2016). Avaliação da Atividade Antioxidante dos Compostos Fenólicos Presentes na Amburana cearensis. Orbital: The Electronic Journal of Chemistry, 1(1), 44–49.

dos Santos Silva, E. L. G., Aguiar, H. T. V., & Freitas, R. F. (2020). Estudo fitoqu’imico, atividade antioxidante e tóxica da casca da Anadenanthera colubrina (Vell.) Brenan. Biodiversidade, 19(2).

Figueiredo, F. J., & Lima, V. (2015). Antioxidant activity of anthocyanins from quixabeira (Sideroxylon obtusifolium) fruits. Revista Brasileira de Plantas Medicinais, 17, 473–479.

Fonseca, C. R., Antongiovanni, M., Matsumoto, M., Bernard, E., & Venticinque, E. M. (2018). Oportunidades de conservação na Caatinga. Ciência e Cultura, 70(4), 44–51.

Granato, D., Shahidi, F., Wrolstad, R., Kilmartin, P., Melton, L. D., Hidalgo, F. J., Miyashita, K., van Camp, J., Alasalvar, C., Ismail, A. B., & others. (2018). Antioxidant activity, total phenolics and flavonoids contents: Should we ban in vitro screening methods? Food Chemistry, 264, 471–475.

Gunathilake, K., Ranaweera, K., & Rupasinghe, H. P. v. (2018). Change of phenolics, carotenoids, and antioxidant capacity following simulated gastrointestinal digestion and dialysis of selected edible green leaves. Food Chemistry, 245, 371–379.

Guo, H., Guo, S., & Liu, H. (2020). Antioxidant activity and inhibition of ultraviolet radiation-induced skin damage of Selenium-rich peptide fraction from selenium-rich yeast protein hydrolysate. Bioorganic Chemistry, 105, 104431.

Harhaun, R., Kunik, O., Saribekova, D., & Lazzara, G. (2020). Biologically active properties of plant extracts in cosmetic emulsions. Microchemical Journal, 154, 104543.

Hughes, M. C. B., Williams, G. M., Pageon, H., Fourtanier, A., & Green, A. C. (2021). Dietary antioxidant capacity and skin photoaging: a 15-year longitudinal study. Journal of Investigative Dermatology, 141(4), 1111–1118.

Isaac, V. L. B., Cefali, L. C., Chiari, B. G., Oliveira, C., Salgado, H. R. N., & Correa, M. A. (2008). Protocolo para ensaios f’isico-qu’imicos de estabilidade de fitocosméticos. Revista de Ciências Farmacêuticas Básica e Aplicada, 29(1).

Júnior, W. S. F., Ladio, A. H., & de Albuquerque, U. P. (2011). Resilience and adaptation in the use of medicinal plants with suspected anti-inflammatory activity in the Brazilian Northeast. Journal of Ethnopharmacology, 138(1), 238–252.

Lataliza, A. A. B., Cavalli, J., Amarante, C. B., Barbosa, D. B., Brandão, M. A. F., Dutra, R. C., & Rapozo, N. R. B. (2019). Antioxidant, cytotoxic, antiproliferative and acetylcholinesterase inhibition properties of the extract from Amburana cearensis. Journal of Multidisciplinary Engineering Science and Technology, 6, 9336–9343.

Leal, L., Ferreira, A. A. G., Bezerra, G. A., Matos, F. J. A., & Viana, G. S. B. (2000). Antinociceptive, anti-inflammatory and bronchodilator activities of Brazilian medicinal plants containing coumarin: a comparative study. Journal of Ethnopharmacology, 70(2), 151–159.

Leite, E. J. (2005). State-of-knowledge on Amburana cearensis (Fr. Allem.) AC Smith (Leguminosae: Papilionoideae) for genetic conservation in Brazil. Journal for Nature Conservation, 13(1), 49–65.

Lima, L. B., Vasconcelos, C. F. B., Maranhão, H. M. L., Leite, V. R., Ferreira, P. A., Andrade, B. A., Araújo, E. L., Xavier, H. S., Lafayette, S. S. L., & Wanderley, A. G. (2009). Acute and subacute toxicity of Schinus terebinthifolius bark extract. Journal of Ethnopharmacology, 126(3), 468–473.

Luna, E. M., Lopes, H. T. O., Rodrigues, F. A. Á., Coutinho, H. D. M., & de Oliveira, L. C. C. (2022). Antioxidant potential of the Caatinga flora. Phytomedicine Plus, 100240.

Martins, F. J., Caneschi, C. A., Vieira, J. L. F., Barbosa, W., & Raposo, N. R. B. (2016). Antioxidant activity and potential photoprotective from amazon native flora extracts. Journal of Photochemistry and Photobiology B: Biology, 161, 34–39.

Melo, P. S., Bergamaschi, K. B., Tiveron, A. P., Massarioli, A. P., Oldoni, T. L. C., Zanus, M. C., Pereira, G. E., & Alencar, S. M. de. (2011). Composição fenólica e atividade antioxidante de res’iduos agroindustriais. Ciência Rural, 41, 1088–1093.

Merecz-Sadowska, A., Sitarek, P., Kucharska, E., Kowalczyk, T., Zajdel, K., Cegliński, T., & Zajdel, R. (2021). Antioxidant properties of plant-derived phenolic compounds and their effect on skin fibroblast cells. Antioxidants, 10(5), 726.

Monção, N. B. N., Costa, L. M., Arcanjo, D. D. R., Araújo, B. Q., Lustosa, M. do C. G., da França Rodrigues, K. A., de Amorim Carvalho, F. A., Costa, A. P. R., & Citó, A. M. das G. L. (2014). Chemical constituents and toxicological studies of leaves from Mimosa caesalpiniifolia Benth., a Brazilian honey plant. Pharmacognosy Magazine, 10(Suppl 3), S456.

Montagner, S., & Costa, A. (2009). Bases biomoleculares do fotoenvelhecimento. Anais Brasileiros de Dermatologia, 84, 263–269.

Nadeeshani Dilhara Gamage, D. G., Dharmadasa, R. M., Chandana Abeysinghe, D., Saman Wijesekara, R. G., Prathapasinghe, G. A., & Someya, T. (2022). Global Perspective of Plant-Based Cosmetic Industry and Possible Contribution of Sri Lanka to the Development of Herbal Cosmetics. Evidence-Based Complementary and Alternative Medicine, 2022.

Ndhlovu, P. T., Mooki, O., Mbeng, W. O., & Aremu, A. O. (2019). Plant species used for cosmetic and cosmeceutical purposes by the Vhavenda women in Vhembe District Municipality, Limpopo, South Africa. South African Journal of Botany, 122, 422–431.

Nunes, A. R., Rodrigues, A. L. M., de Queiróz, D. B., Vieira, I. G. P., Neto, J. F. C., Junior, J. T. C., Tintino, S. R., de Morais, S. M., & Coutinho, H. D. M. (2018). Photoprotective potential of medicinal plants from Cerrado biome (Brazil) in relation to phenolic content and antioxidant activity. Journal of Photochemistry and Photobiology B: Biology, 189, 119–123.

Oliveira, C., Costa, S., Ribeiro, P. R., de Castro, R. D., & Fernandez, L. G. (2013). Avaliação da atividade antioxidante em amostras comerciais de Schinus terebinthifolius (aroeira vermelha). Revista de Ciências Médicas e Biológicas, 12(3), 312–317.

OLIVEIRA, G. L. da S. (2015). Determinação da capacidade antioxidante de produtos naturais in vitro pelo método do DPPH•: estudo de revisão. Revista Brasileira de Plantas Medicinais, 17, 36–44.

Oliveira, M. B. S., Valentim, I. B., Rocha, T. S., Santos, J. C., Pires, K. S. N., Tanabe, E. L. L., Borbely, K. S. C., Borbely, A. U., & Goulart, M. O. F. (2020). Schinus terebenthifolius Raddi extracts: From sunscreen activity toward protection of the placenta to Zika virus infection, new uses for a well-known medicinal plant. Industrial Crops and Products, 152, 112503.

Pessoa, W. S., Estevão, L. R. de M., Sim~oes, R. S., Mendonça, F. de S., Evêncio-Luz, L., Baratella-Evêncio, L., Florencio-Silva, R., Sá, F. B. de, & Evêncio-Neto, J. (2015). Fibrogenesis and epithelial coating of skin wounds in rats treated with angico extract (Anadenanthera colubrina var. cebil). Acta Cirurgica Brasileira, 30, 353–358.

Petchidurai, G., Nagoth, J. A., John, M. S., Sahayaraj, K., Murugesan, N., & Pucciarelli, S. (2019). Standardization and quantification of total tannins, condensed tannin and soluble phlorotannins extracted from thirty-two drifted coastal macroalgae using high performance liquid chromatography. Bioresource Technology Reports, 7, 100273.

Pinto, E. G., Cavalcante, F. S., & Lima, R. A. (2020). A fitoterapia no tratamento de pele: um estudo bibliográfico. Biodiversidade, 19(3).

Sandra Liliana, P.-D., Manasés, G.-C., Enrique, J.-F., Rubén, R.-R., Cinthya, B.-P., Belen, M.-H. G., Alejandro, Z., & Maribel, H.-R. (2021). Isolation, chemical characterization, and anti-inflammatory activity of coumarins, flavonoids, and terpenes from Tagetes lucida. Natural Product Research, 1–6.

Saraiva, M. E., de Alencar Ulisses, A. V. R., Ribeiro, D. A., de Oliveira, L. G. S., de Macedo, D. G., de Sousa, F. de F. S., de Menezes, I. R. A., Sampaio, E. V. de S. B., & de Almeida Souza, M. M. (2015). Plant species as a therapeutic resource in areas of the savanna in the state of Pernambuco, Northeast Brazil. Journal of Ethnopharmacology, 171, 141–153.

Senigalia, R. L. C., de Souza Ferreira, A. L., Kratz, D., Coelho, M. de F. B., dos Santos, A. S. R. M., & Castro, D. A. (2020). Toxicidade de extratos vegetais de plantas do cerrado de uso medicinal. Brazilian Journal of Development, 6(8), 55308–55317.

Shen, N., Wang, T., Gan, Q., Liu, S., Wang, L., & Jin, B. (2022). Plant flavonoids: Classification, distribution, biosynthesis, and antioxidant activity. Food Chemistry, 132531.

Tavares De Souza, M., Dias Da Silva, M., & de Carvalho, R. (2010). Revisão integrativa: o que é e como fazer Integrative review: what is it? How to do it? (Vol. 8, Issue 1).

Zeppelini, D., Queiroz, G. C., Abrantes, E. A., Bellini, B. C., Medeiros, E. S. F., Oliveira, E. P., Silveira, T. C., Neves, A. C. R., Soares, A. F., Godeiro, N. N., & others. (2013). Diversity of Collembola (Arthropoda: Hexapoda) across different types of vegetation in Brazil. International Journal of Biodiversity and Conservation, 5(3), 176–184.

Published

24/12/2022

How to Cite

SILVA, P. M. da .; ROCHA, L. P. B. da .; ARRUDA, L. G. de .; SILVA, B. V. S. da .; SILVA, T. F. da .; COSTA, W. K.; OLIVEIRA, W. F. de .; SILVA, V. B. G. .; SILVA, M. V. da .; CORREIA, M. T. dos S. . Natural products from the Brazilian Caatinga as a sustainable source of phytocosmetics: a review. Research, Society and Development, [S. l.], v. 11, n. 17, p. e167111736940, 2022. DOI: 10.33448/rsd-v11i17.36940. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/36940. Acesso em: 23 nov. 2024.

Issue

Section

Review Article