Clinical and Epidemiological Profile of patients with Chronic Obstructive Pulmonary Disease from a Reference Center in Alagoas: a cross-sectional study

Authors

DOI:

https://doi.org/10.33448/rsd-v11i15.36975

Keywords:

Chronic Obstructive Pulmonary Disease; GOLD; Spirometry; Lung.

Abstract

Objective: To characterize the clinical-epidemiological profile – based on parameters of functional respiratory capacity, dyspnea, gravity and sociodemographic characteristics – two patients with COPD monitored at a pneumology reference center in Alagoas. Methodology: This is an observational and cross-sectional study, based on the application of a standardized questionnaire - Modified British Medical Research Council (mMRc), assessment of medical records and spirometry of patients previously diagnosed with COPD in the Pulmonology sector of the Hospital Universitário Professor Alberto Antunes (HUPAA). Results: A total of 46 patients were analyzed, obtaining a profile of female elderly (63%) who had or have smoking habits (78.3%) and other comorbidities, predominantly of cardiovascular origin. To assess the Global Initiative for Chronic Obstructive Lung Disease (GOLD) scale of patients, the mMRC was applied together with the number of annual exacerbations of the disease and classified as A (52%), B (19.5%), C (2.1%) or D (26%). As for the severity of the disease, the Forced Expiratory Value in the First Second (FEV1) was less than 50% of the predicted value in more than 70% of the patients, therefore, considered severe or very severe. Conclusion: The epidemiological profile of patients is consistent with world studies, with the exception of the prevalence of women to the detriment of men. Patients have a relatively average quality of life based on the mMRC. On the other hand, in terms of disease severity, patients with severe and very severe COPD stand out.

References

Adeloye, D. G., Chua, S., Lee, C., Basquill, C., Papana, A., Theodoratou, E., & Rudan, I. (2015). Global Health Epidemiology Reference Group (GHERG). Global and regional estimates of COPD prevalence: Systematic review and meta-analysis. J Glob Health. 5(2).

American Academy of Family Physicians, American Dietetic Association (2002). A physician's guide to nutrition in chronic disease management for older adults. Washington, DC: Nutrition Screening Initiative.

BRASIL, Ministério da Saúde. Banco de dados do Sistema Único de Saúde DATASUS. Sistema de Informações Hospitalares (SIH) (2021). Disponível em: http://www.datasus.gov.br.

Caram, L. M. O., Ferrari, R., Naves, C. R., Coelho, L. S., Vale, S. A., Tanni, S. E., & Godoy, I. (2016). Risk factors for cardiovascular disease in patients with COPD: mild-to-moderate COPD versus severe-to-very severe COPD. Jornal Brasileiro de Pneumologia. 42(3), 179-184.

Celi, A., Latorre, M., Paggiaro, P., & Pistelli R. (2021). Chronic obstructive pulmonary disease: moving from symptom relief to mortality reduction. Therapeutic Advences in Chronic Disease. 12.

Celli, B. R., & Wedzicha, J. A. (2019). Update on Clinical Aspects of Chronic Obstructive Pulmonary Disease. N Engl J Med. 381(13), 1257-1266.

Cheng, S-L., Lin, C-H., Wang, C-C., Chan, M-C., Hsu, J-Y., Hang, L-W. & Wang, H-C. (2019). Taiwan Clinical Trial Consortium for Respiratory Disease (TCORE). Comparison between COPD Assessment Test (CAT) and modified Medical Research Council (mMRC) dyspnea scores for evaluation of clinical symptoms, comorbidities and medical resources utilization in COPD patients. J Formos Med Assoc. 118, 429-435.

Cruz, M. M., & Pereira, M. (2020). Epidemiology of Chronic Obstructive Pulmonary Disease in Brazil: a systematic review and meta-analysis. Ciênc. Saúde Coletiva. 25(11).

Gedebjerg, A., Szepligeti, S. K., Wackerhausen, L. H., Horváth-Puhó, E., Dahl, R., Hansen, J. G. … & Thomsen, R. W. (2018). Prediction of mortality in patients with chronic obstructive pulmonary disease with the new Global Initiative for Chronic Obstructive Lung Disease 2017 classification: a cohort study. Lancet Respir Med. 6, 204–212.

Global Initiative for Chronic Obstructive Lung Disease (GOLD) (2020). Global Strategy for The Diagnosis, Management, And Prevention of Chronic Obstructive Lung Disease Report. Fontana: GOLD.

Gonçalves-Macedo, L., Lacerda, E. M., Markman-Filho, B., Lundgren, F. L. C., & Luna, C. F. (2019). Tendências da morbidade e mortalidade da DPOC no Brasil, de 2000 a 2016. J Bras Pneumol. 45(6).

Han, M. K. (2020). Chronic obstructive pulmonary disease in women: a biologically focused review with a systematic search strategy. Int J Chron Obstruct Pulmon Dis. 15, 711-721.

Harmon-Weiss, S. (2002). Chronic obstructive pulmonary disease: nutrition management for older adults. Washington, DC: Nutrition Screening Initiative.

Kovelis, D., Segretti, N. O., Probst, V. S., Lareau, S. C., Brunetto, A. F., & Pitta, F. (2008). Validation of the Modified Pulmonary Functional Status and Dyspnea Questionnaire and the Medical Research Council scale for use in Brazilian patients with chronic obstructive pulmonary disease. J Bras Pneumol. 34(12):1008-18.

Labaki, W. W., & Rosenberg, S. R. (2020). Chronic Obstructive Pulmonary Disease. Ann Intern Med. 173(3).

Lopes, A. J., & Melo, P. L. (2016). Brazilian studies on pulmonar function in COPD patients: what are the gaps? Int J Chron Obstruct Pulmon Dis. 11, 1553-1567.

Miravitlles, M., Menezes, A., López Varela, M. V., Casas, A., Ugalde, L., Ramirez-Venegas, A. ... & Oca, M. M. (2018). Prevalence and impact of respiratory symptoms in a population of patients with COPD in Latin America: the LASSYC observational study. Respir Med. 134, 62-9.

Mouronte-Roibás, C., Leiro-Fernández, V., Fernández-Villar, A., Botana-Rial, M., Ramos-Hernández, C., & Ruano-Ravina, A. (2016). COPD, emphysema and the onset of lung cancer. A systematic review. Cancer Lett. 382(2), 240-244.

Oca, M. M., Varela, M. V. P., Menezes, A. M. B., Wehrmeister, F. C., Ramirez, L., & Miravitlles, M. (2021). Respiratory symptoms (COPD Assessment Test and modified Medical Research Council dyspnea scores) and GOLD-ABCD COPD classification: the LASSYC study. Jornal Brasileiro de Pneumologia. 47(5).

Ruvuna, L., & Sood, A. (2020). Epidemiology of Chronic Obstructive Pulmonary Disease. Clin Chest Med. 41(3), 315-327.

Sandelowsky, H., Weinreich, U. M., Aarli, B. B., Sundh, J., Høines, K., Stratelis, G. & Larsson, K. (2021). COPD - do the right thing. BMC Fam Pract. 22(1), 244.

Universidade Federal de Alagoas (2019). Hospital Universitário tem o maior serviço de função pulmonar para o SUS-AL. https://ufal.br/ufal/noticias/2019/9/hospital-universitario-da-ufal-dispoe-do-maior-servico-de-funcao-pulmonar-para-o-sus

Varmaghani, M., Dehghani, M., Heidari, E., Sharif, F., Moghaddam, S. S., & Farzadfar, F. (2019). Global prevalence of chronic obstructive pulmonary disease: systematic review and meta-analysis. East Mediterr Health J. 25(1), 47-57.

Vogelmeier, C. F., Criner, G. J., Martinez, F. J., Anzueto, A., Barnes, P. J., Bourbeau, J. & Agustí, A. (2017). Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report. GOLD Executive Summary. Am J Respir Crit Care Med. 95(5), 557-582.

Zhu, B., Wang, Y., Ming, J., Chen, W., & Zhang, L. (2018). Disease burden of COPD in China: a systematic review. Int J Chron Obstruct Pulmon Dis. 13, 1353-1364.

Published

14/11/2022

How to Cite

PASCOAL, D. B.; ARAUJO, I. M. de; PAIVA, K. V. de L.; ANJOS, T. M. dos; TAVARES, M. M. de A.; PEREIRA, E. B. C.; ROCHA, T. M. da C.; CARVALHO, C. N. de; LOPES, T. P.; ANDRADE, K. C. L. de. Clinical and Epidemiological Profile of patients with Chronic Obstructive Pulmonary Disease from a Reference Center in Alagoas: a cross-sectional study. Research, Society and Development, [S. l.], v. 11, n. 15, p. e198111536975, 2022. DOI: 10.33448/rsd-v11i15.36975. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/36975. Acesso em: 19 apr. 2024.

Issue

Section

Health Sciences