Innovations in chronic pain treatment
DOI:
https://doi.org/10.33448/rsd-v11i16.38205Keywords:
Pain; Chronic; Updates; Management.Abstract
Objective: Chronic pain occurs when the painful sensation persists for more than three months. It affects about 30% of patients and is the main reason for seeking medical attention and using drugs. Drug therapy is an important tool that aims to increase the individual's quality of life, as well as non-drug therapy in a multidisciplinary approach. Thus, this study aimed to evaluate new treatment options to address chronic pain. Methodology: A literature review was carried out using the descriptors “updates”, “management”, “chronic pain” in the following databases: PubMed; Scientific Electronic Library Online (SCIELO); Latin American and Caribbean Literature in Health Sciences (LILACS), in addition to the books “Miller Anestesia” 9th ed and Treaty of Musculoskeletal Pain, from the Brazilian Society of Orthopedics and Traumatology. Results and Discussion: Currently, there are several drugs available, the main ones being: opioids, nonsteroidal anti-inflammatory drugs, antidepressants, antiepileptics and serotonergic compounds. Studies on the use of cannabinoids have grown in recent years, but there is still no evidence for its use as a first-line treatment in this pathology. Opioids are effective for pain of oncological origin, while those derived from other pathophysiological processes respond better to other available options, such as dual antidepressants or antiepileptics. It is important to include physical activity, psychotherapy and physiotherapy when necessary. In addition, botulinum toxin has gained prominence for its effectiveness in the intervention. Conclusion: Chronic pain is a complex disease that involves organic and emotional processes and requires pharmacological and non-pharmacological management.
References
Barret, W., Buxhoeveden, M., & Dhillon, S. (2020). Ketamine: a versatile tool for anesthesia and analgesia. Current Opinion in Anaesthesiology, 33(5), 633–638.
Bicego A, Monseur J, Collinet A, Donneau A-F, Fontaine R, Libbrecht D, et al. (2021) Complementary treatment comparison for chronic pain management: A randomized longitudinal study. PLOS ONE 16(8): e0256001.
Caregnato, R.C & Mutti, R. Pesquisa qualitativa: análise de discurso versus análise de conteúdo. Texto Contexto Enfermagem, 15(4).
Cohen, S. P., Vase, L., & Hooten, W. M. (2021). Chronic pain: an update on burden, best practices, and new advances. The Lancet, 397(10289), 2082–2097.
Cooper, T. E., & et al. (2017). Opioids for chronic non-cancer pain in children and adolescentes. Cochrane Database of Systematic Review, 7(CD012538).
Derry, S., & et al. (2019). Pregabalin for neuropathic pain in adults. Cochrane Database of Systematic Review, 1(CD007076).
Ercole, F. F; Melo, L.S & Alcoforado, C.L.G.C. (2014). Revisão Integrativa versus Revisão Sistemática. Revista Mineira de Enfermagem, 18(1).
Grooper, M. A., & et al. (2019). Miller Anestesia (9a ed.). Elsevier.
Kobayashi, R., & et al. (2018). Tratado de dor musculoesquelética da Sociedade Brasileira de Ortopedia e Traumatologia (SBOT) (2a ed.). Atheneu.
Low, M. Y., & et al. (2020). Vocal music therapy for chronic pain: a mixed methods feasibility study. The Journal of Alternative and Complementary Medicine, 26(2), 113–122.
LV, Z.-T., & et al. (2019). Effects of intensity of electroacupuncture on chronic pain in patients with knee osteoarthritis: a randomized controlled trial. Arthritis Research & Therapy, 21(120).
Maharajan, M. K., & et al. (2019). Medical cannabis for chronic pain: can it make a diference in pain management? Journal of Anesthesia, 34(1), 95–103.
Mücke, M., & et al. (2018). Cannabis‐based medicines for chronic neuropathic pain in adults. Cochrane database of systematic reviews, 3(CD012182).
Nambi, G. (2019). Spinal manipulation combined with Laser therapy is more beneficial than Laser therapy alone in chronic non-specific low back pain – A Randomized controlled study. European Journal of Physical and Rehabilitation Medicine, 54(6), Artigo 10.23736/S1973-9087.18.05005-0.
Oliveira, C. B., & et al. (2018). Clinical practice guidelines for the management of non specifc low back pain in primary care: an updated overview. European Spine Journal, 21(11), 2791–2803.
Pak, D. J., & et al. (2018). Chronification of pain: mechanisms, current understanding, and clinical implications. Current pain and headache reports, 22(2), 1–6.
Schmid, A. A., & et al. (2019). Yoga improves occupational performance, depression, and daily activities for people with chronic pain. Work, 63(2), 181–189.
Siracusa, R. (2021). Fibromyalgia: pathogenesis, mechanisms, diagnosis and treatment options update. International journal of molecular sciences, 22(8), 3891.
Sousa, E., & et al. (2019). Botulinum toxin type A in chronic neuropathic pain in refractory leprosy. Arquivos de Neuro-Psiquiatria, 77, 346–351.
Souza, M. T. d., Silva, M. D. d., & Carvalhp, R. d. (2010). Revisão integrativa: o que é e como fazer. Einstein, 8(1), 102–106.
Urits, I., & et al. (2020). Use of cannabidiol (CBD) for the treatment of chronic pain. Best practice & research clinical anesthesiology, 34(3), 463–477.
Weizman, L. (2018). Cannabis analgesia in chronic neuropathic pain is associated with altered brain connectivity. Neurology, (10.1212).
Welsch, P., & et al. (2018). Serotonin and noradrenaline reuptake inhibitors (SNRIs) for fibromyalgia. Cochrane Database of Systematic Reviews, 2.
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