Evaluation of the prevalence of hepatitis C virus through rapid test in public health services users in Campina Grande-PB
DOI:
https://doi.org/10.33448/rsd-v12i1.39499Keywords:
Hepatitis C; Point-of-Care Systems; Prevalence; Epidemiology.Abstract
Chronic hepatitis C is a silent evolution disease that can lead to outcomes such as liver cirrhosis and hepatocellular carcinoma (HCC), a public health problem due to high universal morbidity. It is transmitted by single-stranded ribonucleic acid (RNA) virus, discovered in 1989 through studies of contaminated chimpanzees. Unsafe health practices, use of illegal intravenous drugs and tattoos are among the major risk factors for the transmission of this virus. Currently, it is estimated that 71 million people are infected worldwide, in Brazil, the prevalence of 0.7% indicates that 1.032.000 individuals are contaminated. With quick execution and rapid results availability, Rapid Tests (RT) facilitate epidemiological studies and early diagnosis of hepatic impairment, allowing the modification of the natural history of the disease. To evaluate the presence of Anti-HCV antibodies and epidemiological characteristics of hepatitis C in users of health services in Campina Grande-PB. A prospective cross-sectional observational study, from February 2015 to July 2018. Individuals born between 1945 and 1970 who sought health services voluntarily underwent structured questionnaires and the Bioeasy® Rapid Anti-HCV Test. A total of 385 individuals were studied, with a prevalence of Anti-HCV antibodies of 1.84% (n = 7). Of the interviewees, the majority (29.7%) were in the age group between 45 and 50 years and 67.7% were female. Intravenous illicit drug use, tattooing and male sex presented the highest statistical relevance as a risk factor in the study population. A prevalence higher than that estimated for the country was found, which highlights the need to implement strategies aimed at the early detection of virus carriers.
References
Barbosa, A. R. (2015). Prevalence of hepatitis c in passers-by at the Alcides Carneiro University Hospital. Monography (Specialization) - Universidade Federal de Campina Grande. Campina Grande, 2015.
Bonfim, R. O.. Andrade, R. L. de P., Reis, R. K.., Ferreira, M. R. L., Orfão, N. H., Villa, T. C. S., & Monroe, A. A. (2021). Quality of life of people with HIV/hepatitis C coinfection: a systematic review. Research, Society and Development, 10(10), e256101018162, 2021.
Brasil. (2015). Ministry of Health. Health Surveillance Secretary. Department of STD, AIDS and Viral Hepatitis. The technical manual for the diagnosis of viral hepatitis. Brasília: Ministry of Health, 2015.
Brasil. (2017). Ministry of Health. Health Surveillance Secretary. Epidemiological Bulletin. Viral hepatitis. Brasilia: Ministry of Health, 2017.
Brasil. (2018). Ministry of Health. Health Surveillance Department. Department of Surveillance, Prevention and Control of STIs, HIV/AIDS and Viral Hepatitis. Clinical protocol and therapeutic guidelines for hepatitis C and co-infections. Brasília, 2018. 89 p.
Brasil. (2019). Ministério da Saúde. Boletim Epidemiológico de Hepatites Virais. Boletim Epidemiológico. Brasília: Ministério da Saúde, 2021.
Brasil. (2020). Ministério da Saúde. Secretaria de Vigilância em Saúde. Boletim Epidemiológico, 51(29). Brasília: Ministério da Saúde, 2020.
Brasil. (2021). Ministério da Saúde. Secretaria de Vigilância em Saúde. Departamento de Vigilância, Prevenção e Controle das IST, do HIV/Aids e das Hepatites Virais. Boletim Epidemiológico de Hepatites Virais. Brasília: Ministério da Saúde, 2021.
Carvalho, F. H. P de, Silva, A. N. M. R da, Melo, H. R. L., & Coêlho, M. R. C. D. (2006). Prevalence of anti-HCV in HIV-seropositive patients. Revista Paraense de Medicina, 20(3), 11-13.
Choo, Q. L., Kuo, G., Weiner, A. J., Overby, L. R., Bradley, D. W., & Houghton, M. (1989). Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome. Science. 21(24), 359-362.
Ciorlia, L. A. S., & Zaneta, D. M. T. (2007). Hepatitis C in healthcare professionals: prevalence and association with risk factors. Revista de Saúde Pública., 41(2), 229-235.
Gomes, D. T. Epidemiological profile of hepatitis c carriers and the vulnerability of the population: potentials for nursing. (2010). Dissertation (Master's in Nursing) - Universidade Federal do Estado do Rio de Janeiro. Rio de Janeiro, 2010.
Maertens, G., Mizokami, M., Murphy, D. G., Okamoto, H., Pawlotsky, J. M., Penin, F., Sablon, E., Shin-I, T., Stuyver, LJ, Thiel, H. J., Viazov, S., Weiner, A. J., & Widell, A. (2005). Consensus proposals for a unified system of nomenclature of hepatitis C virus genotypes. Hepatology, 42(4), 962-73.
Melo, T. R. de., Sá, G., Cordeiro, L. V., Figueiredo, P. T., Ferreira, S. B., & Sousa, A. P. (2022).Perfil Epidemiológico da Hepatite C no Brasil no período de 2013 a 2018. Revista Interdisciplinar em Saúde, 7(1); 1358-1370.
Nogueira, W. P. Prevalência e fatores associados à infecção por sífilis, hiv, hepatite b e c em população ribeirinha. Dissertation (Master’s in Nursing). Universidade Federal da Paraiba. João Pessoa, 2020.
Oliveira, T. J. B., Reis, L. A. P., Barreto, L. S. L. O., Gomes, J. G., & Manrique, E. J. C. (2018). Perfil epidemiológico dos casos de hepatite C em um hospital de referência em doenças infectocontagiosas no estado de Goiás, Brasil. Rev Pan-Amazônica Saúde, 9(1), 2018.
Pereira, L. M., Martelli, C. M., Moreira, R. C., Merchan-Hamman, E., Stein, A. T., Cardoso, M. R., Figueiredo, G. M., Montarroyos, U. R., Braga, C., Turchi, M. D., Coral, G., Crespo, D., Lima, M. L., Alencar, L. C., Costa, M., Santos, A. A., & Ximenes, R. A. (2013). Prevalence and risk factors of Hepatitis C virus infection in Brazil, 2005 through 2009: a cross-sectional study. BMC Infect Dis, 1(13), 60.
Simmonds, P., Bukh, J., Combet, C., Deléage, G., Enomoto, N., Feinstone, S., Halfon, P., Inchauspé, G., Kuiken,, C., Smith, D. B., Bukh, J., Kuiken, C., Muerhoff, A. S., Rice, C. M., Stapleton, J. T., & Simmonds, P. (2014). Expanded classification of hepatitis C virus into 7 genotypes and 67 subtypes: updated criteria and genotype assignment web resource. Hepatology, 59 (1),318-27.
Westbrook, R.H., & Dusheiko, G. (2014). Natural history of hepatitis C. J Hepatology., 61(1 Suppl); 58-68, 2014.
World Health Organization (WHO) (2017). WHO guidelines on hepatitis B and C testing. Geneva, 2017.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Priscila Werton Alves; Maria de Lourdes Albuquerque de Queiroga; Ingrácin Lima Diniz Basílio; Marília Marques Pereira Lira; Damião Flávio dos Santos
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
