Prevalence of the sexual transmission route in the Monkeypox disease
DOI:
https://doi.org/10.33448/rsd-v12i4.40993Keywords:
Monkeypox; Sexual transmitted disease; Sexual and gender minorities.Abstract
This work analyzes whether the hypothesis of sexual transmission by fluids, of the Monkeypox disease, is true and if it can be considered the prevalent one among the other forms of transmission. This is an integrative literature review that consulted the PubMed, Virtual Health Library and Scielo databases in October 2022, comparing articles published between 2018 and October 2022. After the screening steps, 12 articles were included. The main results were grouped into two categories: a) they suggested the hypothesis of sexual transmission as a highly relevant route in contact with Monkeypox Virus (MPXV) and b) they demonstrated the numerical prevalence of sexual transmission in confirmed cases of MPXV. Seven studies suggested the hypothesis of sexual transmission as a highly relevant route in contact with MPXV, while five studies demonstrated the numerical prevalence of sexual transmission in confirmed cases of MPXV. There is an association between MPXV and Sexually Transmitted Infections (STIs), such as HIV, and it is pertinent to recognize the sexual transmission route, by fluids, of monkeypox, as one of the main routes of contamination.
References
Antinori, A., Mazzotta, V., Vita, S., Carletti, F., Tacconi, D., Lapini, L. E., D’Abramo, A., Cicalini, S., Lapa, D., Pittalis, S., Puro, V., Rivano Capparuccia, M., Giombini, E., Gruber, C. E. M., Garbuglia, A. R., Marani, A., Vairo, F., Girardi, E., Vaia, F., & Nicastri, E. (2022). Epidemiological, clinical and virological characteristics of four cases of monkeypox support transmission through sexual contact, Italy, May 2022. Eurosurveillance, 27(22). https://doi.org/10.2807/1560-7917.es.2022.27.22.2200421
Bragazzi, N. L., Kong, J. D., Mahroum, N., Tsigalou, C., Khamisy-Farah, R., Converti, M., & Wu, J. (2022). Epidemiological trends and clinical features of the ongoing monkeypox epidemic: a preliminary pooled data analysis and literature review. Journal of Medical Virology. https://doi.org/10.1002/jmv.27931
Breman, J. G., Kalisa-Ruti, Steniowski, M. V., Zanotto, E., Gromyko, A. I., & Arita, I. (1980). Human monkeypox, 1970-79. Bulletin of the World Health Organization, 58(2), 165–182. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2395797/
Brundu, M., Marinello, S., Scaglione, V., Ferrari, A., Franchin, E., Mazzitelli, M., & Cattelan, A. M. (2022). The first case of monkeypox virus and acute HIV infection: Should we consider monkeypox a new possible sexually transmitted infection? The Journal of Dermatology. https://doi.org/10.1111/1346-8138.16556
Bunge, E. M., Hoet, B., Chen, L., Lienert, F., Weidenthaler, H., Baer, L. R., & Steffen, R. (2022). The changing epidemiology of human monkeypox—A potential threat? A systematic review. PLOS Neglected Tropical Diseases, 16(2), e0010141. https://doi.org/10.1371/journal.pntd.0010141
Cassir, N., Cardona, F., Tissot-Dupont, H., Bruel, C., Doudier, B., Lahouel, S., Bendamardji, K., Boschi, C., Aherfi, S., Edouard, S., Lagier, J.-C., Colson, P., Gautret, P., Fournier, P.-E., Parola, P., Brouqui, P., La-Scola, B., & Million, M. (2022). Observational Cohort Study of Evolving Epidemiologic, Clinical, and Virologic Features of Monkeypox in Southern France. Emerging Infectious Diseases, 28(12). https://doi.org/10.3201/eid2812.221440
Català, A., Clavo Escribano, P., Riera, J., Martín‐Ezquerra, G., Fernandez‐Gonzalez, P., Revelles Peñas, L., Simón Gozalbo, A., Rodríguez‐Cuadrado, F. J., Guilera Castells, V., De la Torre Gomar, F. J., Comunión Artieda, A., Fuertes de Vega, L., Blanco, J. L., Puig, S., García Miñarro, Á. M., Fiz Benito, E., Muñoz‐Santos, C., Repiso‐Jiménez, J. B., Ceballos‐Rodriguez, C., & García Rodríguez, V. (2022). Monkeypox outbreak in Spain: clinical and epidemiological findings in a prospective cross‐sectional study of 185 cases. British Journal of Dermatology. https://doi.org/10.1111/bjd.21790
Cutoiu, A., & Boda, D. (2022). Monkeypox 2022: Dermatologists in the frontline on the edge of a new pandemic: A case report. Experimental and Therapeutic Medicine, 24(5). https://doi.org/10.3892/etm.2022.11613
Duarte, M.G., Amaral, L.J.S., Lyra, Z.M.S., Germano, D.A.F., Rêgo, A.C.B.; Lima, L.A.G., Dantas, F.O., Santiago, G.E.P., Silva, L.B., Cunha, R.S.C. (2022). Monkeypox and its Global Relevance. Research, Society and Development, vol. 11, no. 16, Dec.2022, http://dx.doi.org/10.33448/rsd-v11i16.38483.
El Eid, R., Allaw, F., Haddad, S. F., & Kanj, S. S. (2022). Human monkeypox: A review of the literature. PLOS Pathogens, 18(9), e1010768. https://doi.org/10.1371/journal.ppat.1010768
Girometti, N., Byrne, R., Bracchi, M., Heskin, J., McOwan, A., Tittle, V., Gedela, K., Scott, C., Patel, S., Gohil, J., Nugent, D., Suchak, T., Dickinson, M., Feeney, M., Mora-Peris, B., Stegmann, K., Plaha, K., Davies, G., Moore, L. S. P., & Mughal, N. (2022). Demographic and clinical characteristics of confirmed human monkeypox virus cases in individuals attending a sexual health centre in London, UK: an observational analysis. The Lancet Infectious Diseases, 22(9). https://doi.org/10.1016/s1473-3099(22)00411-x
Harapan, H., Setiawan, A. M., Yufika, A., Anwar, S., Wahyuni, S., Asrizal, F. W., Sufri, M. R., Putra, R. P., Wijayanti, N. P., Salwiyadi, S., Maulana, R., Khusna, A., Nusrina, I., Shidiq, M., Fitriani, D., Muharrir, M., Husna, C. A., Yusri, F., Maulana, R., & Utomo, P. S. (2020). Confidence in managing human monkeypox cases in Asia: A cross-sectional survey among general practitioners in Indonesia. Acta Tropica, 206, 105450. https://doi.org/10.1016/j.actatropica.2020.105450
Lima, E. L. de, Barra, L. A. C., Borges, L. M. S., Medeiros, L. A., Tomishige, M. Y. S., Santos, L. de S. L. A., Silva, A. J. D. da, Rodrigues, C. C. M., Azevedo, L. C. F. de, Villas-Boas, L. S., Silva, C. A. M. da, Coletti, T. M., Manuli, E. R., Claro, I. M., Romano, C. M., Ramundo, M. S., Moutinho, T., Sabino, E. C., Lindoso, J. A. L., & Figueiredo-Mello, C. (2022). First case report of monkeypox in Brazil: clinical manifestations and differential diagnosis with sexually transmitted infections. Revista Do Instituto de Medicina Tropical de São Paulo. https://doi.org/10.1590/s1678-9946202264054
Liu, X., Zhu, Z., He, Y., Lim, J. W., Lane, B., Wang, H., Peng, Q., Sun, L., & Lu, H. (2022). Monkeypox claims new victims: the outbreak in men who have sex with men. Infectious Diseases of Poverty, 11(1). https://doi.org/10.1186/s40249-022-01007-6
Lopes, P. S., Haddad, G. R., & Miot, H. A. (2022). Sexually-transmitted monkeypox: report of two cases. Anais Brasileiros de Dermatologia. https://doi.org/10.1016/j.abd.2022.08.002
McCollum, A. M., & Damon, I. K. (2013). Human Monkeypox. Clinical Infectious Diseases, 58(2), 260–267. https://doi.org/10.1093/cid/cit703
Mendes, K. D. S., Silveira, R. C. de C. P., & Galvão, C. M. (2008). Revisão integrativa: método de pesquisa para a incorporação de evidências na saúde e na enfermagem. Texto & Contexto - Enfermagem, 17(4), 758–764. https://doi.org/10.1590/s0104-07072008000400018
Nakazawa, Y., Mauldin, M., Emerson, G., Reynolds, M., Lash, R., Gao, J., Zhao, H., Li, Y., Muyembe, J.-J., Kingebeni, P., Wemakoy, O., Malekani, J., Karem, K., Damon, I., & Carroll, D. (2015). A Phylogeographic Investigation of African Monkeypox. Viruses, 7(4), 2168–2184. https://doi.org/10.3390/v7042168
Otu, A., Ebenso, B., Walley, J., Barceló, J. M., & Ochu, C. L. (2022). Global human monkeypox outbreak: atypical presentation demanding urgent public health action. The Lancet Microbe, 3(8), e554–e555. https://doi.org/10.1016/s2666-5247(22)00153-7
Page, M. J., McKenzie, J. E., Bossuyt, P. M., Boutron, I., Hoffmann, T. C., Mulrow, C. D., Shamseer, L., Tetzlaff, J. M., Akl, E. A., Brennan, S. E., Chou, R., Glanville, J., Grimshaw, J. M., Hróbjartsson, A., Lalu, M. M., Li, T., Loder, E. W., Mayo-Wilson, E., McDonald, S., & McGuinness, L. A. (2021). The PRISMA 2020 statement: An updated guideline for reporting systematic reviews. British Medical Journal, 372(71). https://doi.org/10.1136/bmj.n71
Patel, A., Bilinska, J., Tam, J. C. H., Fontoura, D. D. S., Mason, C. Y., Daunt, A., Snell, L. B., Murphy, J., Potter, J., Tuudah, C., Sundramoorthi, R., Abeywickrema, M., Pley, C., Naidu, V., Nebbia, G., Aarons, E., Botgros, A., Douthwaite, S. T., Pannerden, C. van N. tot, & Winslow, H. (2022). Clinical features and novel presentations of human monkeypox in a central London centre during the 2022 outbreak: descriptive case series. BMJ, 378, e072410. https://doi.org/10.1136/bmj-2022-072410
Perez Duque, M., Ribeiro, S., Martins, J. V., Casaca, P., Leite, P. P., Tavares, M., Mansinho, K., Duque, L. M., Fernandes, C., Cordeiro, R., Borrego, M. J., Pelerito, A., de Carvalho, I. L., Núncio, S., Manageiro, V., Minetti, C., Machado, J., Haussig, J. M., Croci, R., & Spiteri, G. (2022). Ongoing monkeypox virus outbreak, Portugal, 29 April to 23 May 2022. Eurosurveillance, 27(22). https://doi.org/10.2807/1560-7917.es.2022.27.22.2200424
Petersen, E., Kantele, A., Koopmans, M., Asogun, D., Yinka-Ogunleye, A., Ihekweazu, C., & Zumla, A. (2019). Human Monkeypox. Infectious Disease Clinics of North America, 33(4), 1027–1043. https://doi.org/10.1016/j.idc.2019.03.001
Sah, R., Abdelaal, A., Reda, A., Katamesh, B. E., Manirambona, E., Abdelmonem, H., Mehta, R., Rabaan, A. A., Alhumaid, S., Alfouzan, W. A., Alomar, A. I., Khamis, F., Alofi, F. S., Aljohani, M. H., Alfaraj, A. H., Alfaresi, M., Al-Jishi, J. M., Alsalman, J., Alynbiawi, A., & Almogbel, M. S. (2022). Monkeypox and Its Possible Sexual Transmission: Where Are We Now with Its Evidence? Pathogens, 11(8), 924. https://doi.org/10.3390/pathogens11080924
Shchelkunov, S. N., Totmenin, A. V., Babkin, I. V., Safronov, P. F., Ryazankina, O. I., Petrov, N. A., Gutorov, V. V., Uvarova, E. A., Mikheev, M. V., Sisler, J. R., Esposito, J. J., Jahrling, P. B., Moss, B., & Sandakhchiev, L. S. (2001). Human monkeypox and smallpox viruses: genomic comparison. FEBS Letters, 509(1), 66–70. https://doi.org/10.1016/s0014-5793(01)03144-1
Sklenovská, N., & Van Ranst, M. (2018). Emergence of Monkeypox as the Most Important Orthopoxvirus Infection in Humans. Frontiers in Public Health, 6. https://doi.org/10.3389/fpubh.2018.00241
Souza, M. T. de, Silva, M. D. da, & Carvalho, R. de. (2010). Revisão integrativa: o que é e como fazer. Einstein (São Paulo), 8(1), 102–106. https://doi.org/10.1590/s1679-45082010rw1134
Tarín-Vicente, E. J., Alemany, A., Agud-Dios, M., Ubals, M., Suñer, C., Antón, A., Arando, M., Arroyo-Andrés, J., Calderón-Lozano, L., Casañ, C., Cabrera, J. M., Coll, P., Descalzo, V., Folgueira, M. D., García-Pérez, J. N., Gil-Cruz, E., González-Rodríguez, B., Gutiérrez-Collar, C., Hernández-Rodríguez, Á., & López-Roa, P. (2022). Clinical presentation and virological assessment of confirmed human monkeypox virus cases in Spain: a prospective observational cohort study. The Lancet, 0(0). https://doi.org/10.1016/S0140-6736(22)01436-2
Thornhill, J. P., Barkati, S., Walmsley, S., Rockstroh, J., Antinori, A., Harrison, L. B., Palich, R., Nori, A., Reeves, I., Habibi, M. S., Apea, V., Boesecke, C., Vandekerckhove, L., Yakubovsky, M., Sendagorta, E., Blanco, J. L., Florence, E., Moschese, D., Maltez, F. M., & Goorhuis, A. (2022). Monkeypox Virus Infection in Humans across 16 Countries — April–June 2022. New England Journal of Medicine, 387(8). https://doi.org/10.1056/nejmoa2207323
Vallée, A., Farfour, E., & Zucman, D. (2022). Monkeypox virus: A novel sexually transmitted disease? A case report from France. Travel Medicine and Infectious Disease, 49, 102394. https://doi.org/10.1016/j.tmaid.2022.102394
Vivancos, R., Anderson, C., Blomquist, P., Balasegaram, S., Bell, A., Bishop, L., Brown, C. S., Chow, Y., Edeghere, O., Florence, I., Logan, S., Manley, P., Crowe, W., McAuley, A., Shankar, A. G., Mora-Peris, B., Paranthaman, K., Prochazka, M., Ryan, C., & Simons, D. (2022). Community transmission of monkeypox in the United Kingdom, April to May 2022. Eurosurveillance, 27(22). https://doi.org/10.2807/1560-7917.es.2022.27.22.2200422
Zumla, A., Valdoleiros, S. R., Haider, N., Asogun, D., Ntoumi, F., Petersen, E., & Kock, R. (2022). Monkeypox outbreaks outside endemic regions: scientific and social priorities. The Lancet Infectious Diseases, 22(7)(929-931). https://doi.org/10.1016/s1473-3099(22)00354-1
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Letícia de Queiroz Cunha; Larissa Galvão Rosado; Fernando Marinho Filho; Gabriela Martins Silva ; Gustavo Fernandes do Vale ; Daniele Maria Lopes Pinheiro; Beatriz Cunha Lisboa De Medeiros Nunes
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.