Lymph node metastasis from atypical meningioma: case report

Authors

DOI:

https://doi.org/10.33448/rsd-v12i4.41303

Keywords:

Meningioma; Lymph node; Metastasis.

Abstract

The meninges are connective tissue structures that surround the central nervous system (CNS) and their functions include mechanical protection and formation of the blood-brain barrier. In turn, meningiomas are CNS tumors, mostly benign, which originate from non-epithelial precursor cells of the meninges. The aim of this paper is to describe an uncommon case in the medical literature: the incidence of metastasis from a grade II cranial meningioma to a lymph node in the cervical chain. Thus, we report the case of an elderly man who underwent a computed tomography of the skull after a mild domestic incident, which showed the existence of an intracranial tumor, the patient being asymptomatic. From then on, the investigation began, leading to the diagnosis of post-biopsy meningioma. Months later, an abnormal bulge in the cervical region was observed, leading to a new investigation and a new diagnosis: grade II meningioma associated with lymph node metastasis. The surgical approach seems to be preferred in progressively growing, recurrent and symptomatic meningiomas; the association with biological therapies, such as somatostatin analogues, can delay its growth.

References

Bir, S. C., Patra, D. P., Maiti, T. K., Bollam, P., Minagar, A., Nanda, A. (2017). Comparação direta de radiocirurgia com faca gama e microcirurgia para meningiomas de tamanho pequeno. Neurocirurgia Mundial, 101, 170–179.

Figueiredo, E. G., Aguiar, P. H., Córdoba, B. F., Fujimoto, Y., Rotta, J. M., & Marino JR., R. (1998). Meningiomas supratentoriais: diagnóstico, resultados cirúrgicos e complicações. Arquivos De Neuro-psiquiatria, 56(3A), 429–435.

Buerki, R. A., Horbinski, C. M., Kruser, T., Horowitz, P. M., James, C. D., & Lukas, R. V. (2018). An overview of meningiomas. Future oncology (London, England), 14(21), 2161–2177.

Colli, B. O., Machado, H. R., Carlotti, C. G., Jr, Assirati, J. A., Jr, Oliveira, R. S., Gondim, G. G. P., Santos, A. C. D., & Neder, L. (2021). Epidemiological features of meningiomas: a single Brazilian center's experience with 993 cases. Arquivos de neuro-psiquiatria, 79(8), 705–715.

Chew, S. J. Y., Rajesvaran, C., Woo, X., & Goh, C. H. (2021). Atypical meningioma with nodal metastasis: A case report. The Malaysian journal of pathology, 43(3), 453–456.

Dalle Ore, C. L., Magill, S. T., Yen, A. J., Shahin, M. N., Lee, D. S., Lucas, C. G., Chen, W. C., Viner, J. A., Aghi, M. K., Theodosopoulos, P. V., Raleigh, D. R., Villanueva-Meyer, J. E., & McDermott, M. W. (2019). Meningioma metastases: incidence and proposed screening paradigm. Journal of neurosurgery, 132(5), 1447–1455.

Goldbrunner, R., Stavrinou, P., Jenkinson, M. D., Sahm, F., Mawrin, C., Weber, D. C., Preusser, M., Minniti, G., Lund-Johansen, M., Lefranc, F., Houdart, E., Sallabanda, K., Le Rhun, E., Nieuwenhuizen, D., Tabatabai, G., Soffietti, R., & Weller, M. (2021). EANO guideline on the diagnosis and management of meningiomas. Neuro-oncology, 23(11), 1821–1834.

Graillon, T., Sanson, M., Campello, C., Idbaih, A., Peyre, M., Peyrière, H., Basset, N., Autran, D., Roche, C., Kalamarides, M., Roche, P. H., Fuentes, S., Tabouret, E., Barrie, M., Cohen, A., Honoré, S., Boucekine, M., Baumstarck, K., Figarella-Branger, D., Barlier, A., … Chinot, O. L. (2020). Everolimus and Octreotide for Patients with Recurrent Meningioma: Results from the Phase II CEVOREM Trial. Clinical cancer research: an official journal of the American Association for Cancer Research, 26(3), 552–557.

Jung, J. W., & Park, C. (2021). Delayed solitary mediastinal lymph node metastasis from a benign meningothelial meningioma six years after surgical resection of an intracranial tumor. Thoracic cancer, 12(12), 1931–1934.

Kessler, R. A., Garzon-Muvdi, T., Yang, W., Weingart, J., Olivi, A., Huang, J., Brem, H., & Lim, M. (2017). Metastatic Atypical and Anaplastic Meningioma: A Case Series and Review of the Literature. World neurosurgery, 101, 47–56.

Liu, Y., Li, J., Duan, Y., Ye, Y., Xiao, L., & Mao, R. (2020). Subcutaneous Metastasis of Atypical Meningioma: Case Report and Literature Review. World neurosurgery, 138, 182–186.

Maggio, I., Franceschi, E., Tosoni, A., Nunno, V. D., Gatto, L., Lodi, R., & Brandes, A. A. (2021). Meningioma: not always a benign tumor. A review of advances in the treatment of meningiomas. CNS oncology, 10(2), CNS72.

Marosi, C., Hassler, M., Roessler, K., Reni, M., Sant, M., Mazza, E., & Vecht, C. (2008). Meningioma. Critical reviews in oncology/hematology, 67(2), 153–171.

Nguyen, H. C. B., Mady, L. J., Panara, K., Andrianus, S., Cooper, K., Chen, I. H., Chalian, A. A., & Brody, R. M. (2022). Metastatic Meningioma of the Neck: A Case Report and Systematic Review. ORL; journal for oto-rhino-laryngology and its related specialties, 84(5), 361–369.

Nowosielski, M., Galldiks, N., Iglseder, S., Kickingereder, P., von Deimling, A., Bendszus, M., Wick, W., & Sahm, F. (2017). Diagnostic challenges in meningioma. Neuro-oncology, 19(12), 1588–1598.

Patel, N., & Kirmi, O. (2009). Anatomy and imaging of the normal meninges. Seminars in ultrasound, CT, and MR, 30(6), 559–564.

Pereira, A. S., Shitsuka, D. M., Parreira, F. J., Shitsuka, R. (2018). Metodologia da pesquisa científica. UFSM.

Puchner, M. J. A., Hans, V. H., Harati, A., Lohmann, F., Glas, M., & Herrlinger, U. (2010). Bevacizumab-induced regression of anaplastic meningioma. Annals of oncology: official journal of the European Society for Medical Oncology, 21(12), 2445–2446.

Sheng, B., Liu, Y., & Liu, C. (2021). Liver Metastasis from Typical Meningioma. World neurosurgery, 145, 334–337.

Vogelbaum, M. A., Leland Rogers, C., Linskey, M. A., & Mehta, M. P. (2010). Opportunities for clinical research in meningioma. Journal of neuro-oncology, 99(3), 417–422.

Published

18/04/2023

How to Cite

AMARAL, H. S. G. do .; MORAES, M. de S. .; SANTOS, J. F. M. dos .; VALENTE , C. L. .; BRAGA, R. T. de F. .; MAGRANI , G. C. . Lymph node metastasis from atypical meningioma: case report. Research, Society and Development, [S. l.], v. 12, n. 4, p. e26112441303, 2023. DOI: 10.33448/rsd-v12i4.41303. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/41303. Acesso em: 29 may. 2024.

Issue

Section

Health Sciences