Oral manifestations of diabetes mellitus: an integrative review
DOI:
https://doi.org/10.33448/rsd-v12i5.41373Keywords:
Diabetes mellitus; Diabetes complications; Oral manifestations; Dentistry; Oral health.Abstract
Diabetes Mellitus (DM) is a chronic disease characterized by insufficient insulin not produced by the pancreas or by the body's inability to use it, which can lead to hyperglycemia. The metabolic alterations resulting from decompensated DM generate consequences throughout the body, consequently affecting oral health as well. Therefore, it is imperative that dentists are aware of these manifestations in order to provide better dental treatment. In this sense, the aim of this study was to describe the main oral manifestations associated with diabetes mellitus through an integrative literature review. Thus, a search was carried out in the PubMed/Medline, Lilacs and SciELO databases, reaching the final selection of 12 articles for this work. The results revealed a high prevalence of oral alterations such as xerostomia, dental caries, periodontal disease and stomatitis in patients with DM. Thus, it was found that DM is associated with oral manifestations such as salivary, dental, periodontal and soft tissue alterations. Therefore, the importance of the dentist in the early diagnosis and/or control of possible complications associated with DM is clear.
References
Alves, B. /. O. /. (n.d.). Diabetes. Gov.br. Retrieved May 1, 2023, from https://bvsms.saude.gov.br/diabetes/
Andrade, E. D. (2013). Terapêutica Medicamentosa em Odontologia. 3a. Artes Médicas.
Bajaj, S., Prasad, S., Gupta, A., & Singh, V. B. (2012). Oral manifestations in type-2 diabetes and related complications. Indian Journal of Endocrinology and Metabolism, 16(5), 777–779. https://doi.org/10.4103/2230-8210.100673
Busato, I. M. S., Ignácio, S. A., Brancher, J. A., Moysés, S. T., & Azevedo-Alanis, L. R. (2012). Impact of clinical status and salivary conditions on xerostomia and oral health-related quality of life of adolescents with type 1 diabetes mellitus: OHQoL of adolescents with type 1 diabetes mellitus. Community Dentistry and Oral Epidemiology, 40(1), 62–69. https://doi.org/10.1111/j.1600-0528.2011.00635.x
De Carli, J. P., Lima, I. F. P., Verardi, G., Ferreira, M. D. C., da Silva, S. O., & Paranhos, L. R. (2017). Most Frequent Oral Lesions in patients with Type 2 Diabetes Mellitus. The Journal of Contemporary Dental Practice, 18(2), 107–111. https://doi.org/10.5005/jp-journals-10024-1999
Díaz Rosas, C. Y., Cárdenas Vargas, E., Castañeda-Delgado, J. E., Aguilera-Galaviz, L. A., & Aceves Medina, M. C. (2018). Dental, periodontal and salivary conditions in diabetic children associated with metabolic control variables and nutritional plan adherence. European Journal of Paediatric Dentistry: Official Journal of European Academy of Paediatric Dentistry, 19(2), 119–126. https://doi.org/10.23804/ejpd.2018.19.02.05
Ferreira, A. B. D., Melo, C. M., Barbosa, O. L. C., & Barbosa, C. C. N. (2021). Manifestações bucais no paciente diabético. Brazilian Journal of Surgery and Clinical Research, 10–13.
Kakoei, S., Hosseini, B., Haghdoost, A.-A., Sanjari, M., Gholamhosseinian, A., & Afshar, V. F. N. (2015). Evaluation of salivary secretory immunoglobulin A levels in diabetic patients and association with oral and dental manifestations. Sultan Qaboos University Medical Journal, 15(4), e507-11. https://doi.org/10.18295/squmj.2015.15.04.011
Keays, R. (2007). Diabetes. Current Anaesthesia and Critical Care, 18(2), 69–75. https://doi.org/10.1016/j.cacc.2007.03.007
Kheirmand Parizi, M., Akbari, H., Malek-Mohamadi, M., Kheirmand Parizi, M., & Kakoei, S. (2019). Association of salivary levels of immunoglobulin-a and amylase with oral-dental manifestations in patients with controlled and non-controlled type 2 diabetes. BMC Oral Health, 19(1), 175. https://doi.org/10.1186/s12903-019-0868-4
Madi, M., Babu, S., Kumari, S., Shetty, S., Achalli, S., Madiyal, A., & Bhat, M. (2016). Status of serum and salivary levels of Superoxide dismutase in Type 2 Diabetes Mellitus with oral manifestations: A case control study. Ethiopian Journal of Health Sciences, 26(6), 523–532. https://doi.org/10.4314/ejhs.v26i6.4
Majbauddin, A., Tanimura, C., Aoto, H., Otani, S., Parrenas, M. C. E., Kobayashi, N., Morita, T., Inoue, K., Masumoto, T., & Kurozawa, Y. (2019). Association between dental caries indicators and serum glycated hemoglobin-levels among patients with type 2 diabetes mellitus. Journal of Oral Science, 61(2), 335–342. https://doi.org/10.2334/josnusd.18-0156
Mattos, P. C. (2015). Tipos de revisão de literatura. Faculdade de Ciências Agronômicas.
Plessas, A., Robertson, D. P., & Hodge, P. J. (2018). Radiographic bone loss in a Scottish non‐smoking type 1 diabetes mellitus population: A bitewing radiographic study. Journal of Periodontology, 89(9), 1043–1051. https://doi.org/10.1002/jper.16-0788
Sanjeeta, N., Sivapathasundharam, B., & Nandini, D. B. (2022). Oral lesions and periodontal status in diabetics and non-diabetics: A hospital based study. Journal of Oral and Maxillofacial Pathology: JOMFP, 26(3), 419. https://doi.org/10.4103/jomfp.jomfp_37_21
Sociedade Brasileira de Diabetes (2019). Diretrizes da sociedade brasileira de diabetes 2019-2020. Editora Clannad. https://www.saude.ba.gov.br/wp-content/uploads/2020/02/Diretrizes-Sociedade-Brasileira-de-Diabetes-2019-2020.pdf
Sousa, G. L. do C., Leite, L. O. S., & Yamashita, R. K. (2022). Atendimento de pacientes diabéticos na Odontologia. Research, Society and Development, 11(13), e434111335801. https://doi.org/10.33448/rsd-v11i13.35801
Sousa, M. G. de M., Costa, A. de L. L., & Roncalli, A. G. (2011). Clinical study of the oral manifestations and related factors in type 2 diabetics patients. Brazilian Journal of Otorhinolaryngology, 77(2), 145–152. https://doi.org/10.1590/s1808-86942011000200002
Sousa, R., Castro, R., Monteiro, C. H., Silva, S., & Nunes, A. B. (2003). O paciente odontológico portador de Diabetes Mellitus: uma revisão da literatura. Pesq Bras Odontoped Clin Integr.
Contreras-Aguilar, M. D., & Gómez-García, F. (2020). Salivary Glands’ Anatomy and Physiology. In Tvarijonaviciute, A., Martínez-Subiela, S., & López-Jornet, P. (Ed.), Saliva in Health and Disease: The Present and Future of a Unique Sample of Diagnosis (pp. 3–21). Springer International Publishing.
Vieira, L. de P., Cabral, C. W. L. F., Silva, B. A. K. da, & Filgueiras, M. de C. (2022). Prevalência e impacto das manifestações bucais na qualidade de vida de indivíduos com Diabetes Mellitus tipo 2. Research, Society and Development, 11(8), e11711829621. https://doi.org/10.33448/rsd-v11i8.29621
Yamunadevi, A., Basandi, P. S., Madhushankari, G. S., Donoghue, M., Manjunath, A., Selvamani, M., & Puneeth, H. K. (2014). Morphological alterations in the dentition of type I diabetes mellitus patients. Journal of Pharmacy & Bioallied Sciences, 6(Suppl 1), S122-6. https://doi.org/10.4103/0975-7406.137415
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Copyright (c) 2023 Pedro Paullo Alves Gonçalves; Joana D’arc da Silva Sampaio; Núria Irina Gomes dos Reis Freitas; Rebeca Carvalho Raposo; Samira Fonseca de Arruda; Marilia Leal Ferreira Lago; Luana Martins Cantanhede
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